Version: 8.2.0
Date: Wed Aug 27 2025
1,059 results for Col8a2

col8a2

(Danio rerio)
Gene
Name: collagen, type VIII, alpha 2
Synonyms: si:ch211-197n10.4
Source: ZFIN:ZDB-GENE-060503-488
Biotype: protein coding gene
Symbol: col8a2 (Dre)
Symbol: col8a2
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Strict Orthology Symbols: Col8a2

Col8a2

(Mus musculus)
Gene
Name: collagen, type VIII, alpha 2
Synonyms: expressed sequence AI429819, AI429819
Source: MGI:88464
Biotype: protein coding gene
Symbol: Col8a2 (Mmu)
Symbol: Col8a2
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Strict Orthology Symbols: Col8a2
Alleles: Col8a2 (Mmu)...Col8a2 (Mmu)...Col8a2 (Mmu)...Col8a2 (Mmu)

Col8a2

(Rattus norvegicus)
Gene
Name: collagen type VIII alpha 2 chain
Synonyms: collagen, type VIII, alpha 2, LOC313592, collagen alpha-2(VIII) chain, procollagen, type VIII, alpha 2
Source: RGD:1305182
Biotype: protein coding gene
Symbol: Col8a2 (Rno)
Symbol: Col8a2
Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain); PARTICIPATES IN syndecan signaling pathway
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Strict Orthology Symbols: Col8a2

COL8A2

(Homo sapiens)
Gene
Name: collagen type VIII alpha 2 chain
Synonyms: FECD, endothelial collagen, FLJ00201, collagen, type VIII, alpha 2, PPCD, FECD1, MGC116972, MGC116970, collagen VIII, alpha-2 polypeptide, collagen type VIII alpha 2, PPCD2, dJ665N4.1 (collagen type VIII alpha 2), collagen alpha-2(VIII) chain
Source: HGNC:2216
Biotype: protein coding gene
Symbol: COL8A2 (Hsa)
Symbol: COL8A2
Strict Orthology Symbols: Col8a2

col8a2

(Xenopus tropicalis)
Gene
Name: collagen, type VIII, alpha 2
Synonyms: collagen, type VIII, alpha 2, col8a2
Source: Xenbase:XB-GENE-961197
Biotype: gene
Symbol: col8a2 (Xtr)
Symbol: col8a2
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Synonyms: col8a2...col8a2
Strict Orthology Symbols: Col8a2

col8a2.L

(Xenopus laevis)
Gene
Name: collagen, type VIII, alpha 2
Synonyms: col8a2.L, collagen, type VIII, alpha 2
Source: Xenbase:XB-GENE-17330241
Biotype: gene
Symbol: col8a2.L (Xla)
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Strict Orthology Symbols: col8a2...COL8A2
Symbol: col8a2.L

col8a2.S

(Xenopus laevis)
Gene
Name: collagen, type VIII, alpha 2
Synonyms: collagen, type VIII, alpha 2, col8a2.S
Source: Xenbase:XB-GENE-6488345
Biotype: gene
Symbol: col8a2.S (Xla)
Automated Gene Synopsis: Orthologous to human COL8A2 (collagen type VIII alpha 2 chain).
Strict Orthology Symbols: col8a2...COL8A2
Symbol: col8a2.S

Col8a2tm1Bjro

(Mus musculus)
Allele/Variant
Source: MGI:3587617
Genes: Col8a2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Symbol: Col8a2tm1Bjro

Col8a2Aca23/Col8a2Aca23 [background:] C57BL/6J-Col8a2Aca23

(Mus musculus)
Model
Id: MGI:4438460
Synonyms: Not Available
Symbol: Col8a2/Col8a2 [background:] C57BL/6J-Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2 [background:] C57BL/6J-Col8a2

Col8a2tm2.1Asj/Col8a2tm2.1Asj [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA

(Mus musculus)
Model
Id: MGI:5796114
Synonyms: Not Available
Symbol: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA

Col8a2tm1Bjro/Col8a2tm1Bjro [background:] B6.129S4-Col8a2tm1Bjro

(Mus musculus)
Model
Id: MGI:3589471
Synonyms: Not Available
Symbol: Col8a2/Col8a2 [background:] B6.129S4-Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2 [background:] B6.129S4-Col8a2

Col8a2tm1.1Asj/Col8a2tm1.1Asj [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA

(Mus musculus)
Model
Id: MGI:5305276
Synonyms: Not Available
Symbol: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac * C57BL/6 * CBA

Col8a2Aca23/Col8a2+ [background:] C57BL/6J-Col8a2Aca23

(Mus musculus)
Model
Id: MGI:4438459
Synonyms: Not Available
Symbol: Col8a2/Col8a2<+> [background:] C57BL/6J-Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2<+> [background:] C57BL/6J-Col8a2

Col8a2tm1.1Asj/Col8a2tm1.1Asj [background:] involves: 129S6/SvEvTac

(Mus musculus)
Model
Id: MGI:5796117
Synonyms: Not Available
Symbol: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac (Mmu)
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a2/Col8a2 [background:] involves: 129S6/SvEvTac

Col8a2tm2.1Asj

(Mus musculus)
Allele/Variant
Source: MGI:5774727
Genes: Col8a2 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Fuchs' endothelial dystrophy
Variant Name: Not Available
Symbol: Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Symbol: Col8a2tm2.1Asj

Col8a2Aca23

(Mus musculus)
Allele/Variant
Source: MGI:4438451
Genes: Col8a2 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Symbol: Col8a2Aca23

Col8a2tm1.1Asj

(Mus musculus)
Allele/Variant
Source: MGI:5305275
Genes: Col8a2 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Fuchs' endothelial dystrophy
Variant Name: Not Available
Symbol: Col8a2 (Mmu)
Genes: Col8a2 (Mmu)
Symbol: Col8a2tm1.1Asj

col8a1b

(Danio rerio)
Gene
Name: collagen, type VIII, alpha 1b
Synonyms: si:ch73-162i18.4, col8a2
Source: ZFIN:ZDB-GENE-060503-140
Biotype: protein coding gene
Synonyms: col8a2...col8a2

posterior polymorphous corneal dystrophy 2

Disease
Source: DOID:0110856
Definition: A posterior polymorphous corneal dystrophy that has_material_basis_in heterozygous mutation in the COL8A2 gene on chromosome 1p34.3.
Genes: col8a2.S (Xla)...col8a2 (Xtr)...COL8A2 (Hsa)...col8a2 (Dre)...Col8a2 (Rno)

Fuchs' endothelial dystrophy

Disease
Source: DOID:11555
Definition: A corneal dystrophy characterized by accumulation of focal outgrowths (guttae) and thickening of Descemet's membrane, leading to corneal edema and loss of vision.
Genes: col8a2.S (Xla)...col8a2 (Dre)...col8a2.L (Xla)...col8a2 (Xtr)...Col8a2 (Rno)
Alleles: Col8a2 (Mmu)...Col8a2 (Mmu)

collagen type VIII trimer

Gene Ontology
Source: GO:0005591
Synonyms: Not Available
Branch: cellular component
Genes: COL8A2 (Hsa)

Col8a1tm1Bjro/Col8a1tm1Bjro Col8a2tm1Bjro/Col8a2tm1Bjro [background:] B6.129S4-Col8a2tm1Bjro Col8a1tm1Bjro

(Mus musculus)
Model
Id: MGI:3589472
Synonyms: Not Available
Genes: Col8a2 (Mmu)
Alleles: Col8a2 (Mmu)
Name: Col8a1/Col8a1 Col8a2/Col8a2 [background:] B6.129S4-Col8a2
Symbol: Col8a1/Col8a1 Col8a2/Col8a2 [background:] B6.129S4-Col8a2

endothelial cell proliferation

Gene Ontology
Source: GO:0001935
Synonyms: Not Available
Branch: biological process
Genes: COL8A2 (Hsa)...Col8a2 (Rno)...Col8a2 (Mmu)

camera-type eye morphogenesis

Gene Ontology
Source: GO:0048593
Synonyms:
  • camera-style eye morphogenesis
Branch: biological process
Genes: COL8A2 (Hsa)...Col8a2 (Rno)...Col8a2 (Mmu)

extracellular matrix structural constituent conferring tensile strength

Gene Ontology
Source: GO:0030020
Synonyms:
  • core extracellular matrix
  • core matrisome
Branch: molecular function
Genes: COL8A2 (Hsa)...col8a2 (Dre)...Col8a2 (Rno)...Col8a2 (Mmu)

collagen trimer

Gene Ontology
Source: GO:0005581
Synonyms: Not Available
Branch: cellular component
Genes: COL8A2 (Hsa)...Col8a2 (Mmu)...Col8a2 (Rno)...col8a2 (Dre)

basement membrane

Gene Ontology
Source: GO:0005604
Synonyms:
  • basal lamina
  • basement lamina
Branch: cellular component
Genes: COL8A2 (Hsa)...Col8a2 (Mmu)

extracellular matrix

Gene Ontology
Source: GO:0031012
Synonyms:
  • matrisome
  • proteinaceous extracellular matrix
Branch: cellular component
Genes: col8a2 (Dre)...COL8A2 (Hsa)...Col8a2 (Mmu)...Col8a2 (Rno)

angiogenesis

Gene Ontology
Source: GO:0001525
Synonyms:
  • blood vessel formation from pre-existing blood vessels
Branch: biological process
Genes: COL8A2 (Hsa)...Col8a2 (Mmu)

extracellular matrix structural constituent

Gene Ontology
Source: GO:0005201
Synonyms:
  • core extracellular matrix
  • core matrisome
Branch: molecular function
Genes: COL8A2 (Hsa)

extracellular matrix organization

Gene Ontology
Source: GO:0030198
Synonyms:
  • extracellular matrix organisation
  • extracellular matrix organization and biogenesis
Branch: biological process
Genes: COL8A2 (Hsa)

protein-macromolecule adaptor activity

Gene Ontology
Source: GO:0030674
Synonyms:
  • protein binding, bridging
  • protein complex scaffold activity
Branch: molecular function
Genes: COL8A2 (Hsa)

cell-cell adhesion

Gene Ontology
Source: GO:0098609
Synonyms:
  • single organismal cell-cell adhesion
Branch: biological process
Genes: COL8A2 (Hsa)

endoplasmic reticulum lumen

Gene Ontology
Source: GO:0005788
Synonyms:
  • ER cisterna
  • ER lumen
Branch: cellular component
Genes: COL8A2 (Hsa)

cell adhesion

Gene Ontology
Source: GO:0007155
Synonyms:
  • cell adhesion molecule activity
  • single organism cell adhesion
Branch: biological process
Genes: COL8A2 (Hsa)...Col8a2 (Mmu)

sa29815

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-13905
Genes: col8a1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: col8a2

sa14358

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-12724
Genes: col8a1b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: col8a2

sa23569

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-131217-17204
Genes: col8a2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: col8a2 (Dre)

sa23570

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-11719
Genes: col8a2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: col8a2 (Dre)

extracellular space

Gene Ontology
Source: GO:0005615
Synonyms:
  • intercellular space
Branch: cellular component
Genes: COL8A2 (Hsa)

(GRCh38)1:36097799C>T

(Homo sapiens)
Allele/Variant
Source: rs200185433
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36097799C>T

(GRCh38)1:36097872G>A

(Homo sapiens)
Allele/Variant
Source: rs139081156
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36097872G>A

(GRCh38)1:36098021C>T

(Homo sapiens)
Allele/Variant
Source: NC_000001.11:g.36098021C>T
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36098021C>T

(GRCh38)1:36098101G>T

(Homo sapiens)
Allele/Variant
Source: NC_000001.11:g.36098101G>T
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36098101G>T

(GRCh38)1:36098318G>T

(Homo sapiens)
Allele/Variant
Source: rs80358191
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36098318G>T

(GRCh38)1:36098358T>C

(Homo sapiens)
Allele/Variant
Source: rs182708720
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36098358T>C

(GRCh38)1:36100398A>G

(Homo sapiens)
Allele/Variant
Source: rs4652900
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36100398A>G

(GRCh38)1:36100113T>C

(Homo sapiens)
Allele/Variant
Source: rs77354921
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36100113T>C

(GRCh38)1:36098194C>T

(Homo sapiens)
Allele/Variant
Source: rs763868014
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36098194C>T

(GRCh38)1:36097679G>A

(Homo sapiens)
Allele/Variant
Source: rs201587529
Genes: COL8A2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)1:36097679G>A