Version: 8.1.0Date: Fri Apr 18 2025
Category
Gramd4
(Rattus norvegicus)Gene
Name: GRAM domain containing 4
Synonyms: RGD1309983, GRAM domain-containing protein 4, similar to hypothetical protein 9930016O13, death-inducing-protein, Dip, LOC315203
Source: RGD:1309983
Biotype: protein coding gene
Symbol: Gramd4 (Rno)
Symbol: Gramd4
Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: Gramd4
GRAMD4
(Homo sapiens)Gene
Name: GRAM domain containing 4
Synonyms: MGC149847, MGC90497, KIAA0767, dA59H18.1, GRAM domain-containing protein 4, dJ439F8.1, death-inducing-protein, DIP, death-inducing protein
Source: HGNC:29113
Biotype: protein coding gene
Symbol: GRAMD4 (Hsa)
Symbol: GRAMD4
Gene Synopsis: GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed
Strict Orthology Symbols: Gramd4
Gramd4
(Mus musculus)Gene
Name: GRAM domain containing 4
Synonyms: RGD1309983, BC021523, Dip, cDNA sequence BC021523
Source: MGI:2676308
Biotype: protein coding gene
Symbol: Gramd4 (Mmu)
Symbol: Gramd4
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: Gramd4
Alleles: Gramd4
gramd4
(Xenopus tropicalis)Gene
Name: GRAM domain containing 4
Synonyms: gramd4, GRAM domain containing 4
Source: Xenbase:XB-GENE-999025
Biotype: gene
Symbol: gramd4 (Xtr)
Symbol: gramd4
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Synonyms: gramd4...gramd4
Strict Orthology Symbols: Gramd4
gramd4a
(Danio rerio)Gene
Name: GRAM domain containing 4a
Synonyms: gramd4, si:bz6l08.2, si:rp71-6l08.2, si:ch211-162i19.2
Source: ZFIN:ZDB-GENE-041210-211
Biotype: protein coding gene
Symbol: gramd4a (Dre)
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Synonyms: gramd4...gramd4
Strict Orthology Symbols: Gramd4
Symbol: gramd4a
gramd4b
(Danio rerio)Gene
Name: GRAM domain containing 4b
Synonyms: fd60a08, wu:fd60a08, si:ch73-230f23.1
Source: ZFIN:ZDB-GENE-030131-4780
Biotype: protein coding gene
Symbol: gramd4b (Dre)
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: Gramd4
Symbol: gramd4b
gramd4.L
(Xenopus laevis)Gene
Name: GRAM domain containing 4
Synonyms: GRAM domain containing 4, gramd4.L
Source: Xenbase:XB-GENE-17340919
Biotype: gene
Symbol: gramd4.L (Xla)
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: gramd4...GRAMD4
Symbol: gramd4.L
gramd4.S
(Xenopus laevis)Gene
Name: GRAM domain containing 4
Synonyms: GRAM domain containing 4, gramd4.S
Source: Xenbase:XB-GENE-999029
Biotype: gene
Symbol: gramd4.S (Xla)
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: gramd4...GRAMD4
Symbol: gramd4.S
Gramd4em1(IMPC)Mbp
(Mus musculus)Allele/Variant
Source: MGI:7616791
Genes: Gramd4 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gramd4
Genes: Gramd4 (Mmu)
Symbol: Gramd4em1(IMPC)Mbp
GRAMD4P5
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 5
Synonyms: Not Available
Source: HGNC:49140
Biotype: pseudogene
Symbol: GRAMD4P5 (Hsa)
Symbol: GRAMD4P5
GRAMD4P2
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 2
Synonyms: Not Available
Source: HGNC:39654
Biotype: pseudogene
Symbol: GRAMD4P2 (Hsa)
Symbol: GRAMD4P2
GRAMD4P8
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 8
Synonyms: Not Available
Source: HGNC:49143
Biotype: pseudogene
Symbol: GRAMD4P8 (Hsa)
Symbol: GRAMD4P8
GRAMD4P4
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 4
Synonyms: Not Available
Source: HGNC:49139
Biotype: pseudogene
Symbol: GRAMD4P4 (Hsa)
Symbol: GRAMD4P4
GRAMD4P6
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 6
Synonyms: Not Available
Source: HGNC:49141
Biotype: pseudogene
Symbol: GRAMD4P6 (Hsa)
Symbol: GRAMD4P6
GRAMD4P7
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 7
Synonyms: Not Available
Source: HGNC:49142
Biotype: pseudogene
Symbol: GRAMD4P7 (Hsa)
Symbol: GRAMD4P7
GRAMD4P3
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 3
Synonyms: Not Available
Source: HGNC:49138
Biotype: pseudogene
Symbol: GRAMD4P3 (Hsa)
Symbol: GRAMD4P3
GRAMD4P1
(Homo sapiens)Gene
Name: GRAM domain containing 4 pseudogene 1
Synonyms: Not Available
Source: HGNC:39653
Biotype: pseudogene
Symbol: GRAMD4P1 (Hsa)
Symbol: GRAMD4P1
Y77E11A.12
(Caenorhabditis elegans)Gene
Name: GRAM domain-containing protein
Synonyms: CELE_Y77E11A.12
Source: WB:WBGene00022313
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human GRAMD4 (GRAM domain containing 4).
Automated Gene Synopsis: Orthologous to human GRAMD4 (GRAM domain containing 4).
Strict Orthology Symbols: Gramd4
Source: GO:0034164
Synonyms:
- negative regulation of TLR9 signaling pathway
- negative regulation of toll-like receptor 9 signalling pathway
Branch: biological process
Genes: Gramd4 (Mmu)...GRAMD4 (Hsa)...Gramd4 (Rno)...gramd4a (Dre)...gramd4b (Dre)
Gene Ontology
Source: GO:0031966
Synonyms: Not Available
Branch: cellular component
Genes: Gramd4 (Mmu)...GRAMD4 (Hsa)
Gene Ontology
Source: GO:0006915
Synonyms:
- activation of apoptosis
- apoptosis
Branch: biological process
Genes: Gramd4 (Mmu)...Gramd4 (Rno)...GRAMD4 (Hsa)...gramd4a (Dre)...gramd4b (Dre)
Gene Ontology
Source: GO:0043065
Synonyms:
- activation of apoptosis
- positive regulation of apoptosis
Branch: biological process
Genes: Gramd4 (Mmu)...Gramd4 (Rno)...GRAMD4 (Hsa)
sa18012
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-131217-14074
Genes: gramd4b (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: gramd4b (Dre)
sa40309
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-6553
Genes: gramd4a (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: gramd4
Genes: gramd4a (Dre)
sa2167
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-11242
Genes: gramd4a (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: gramd4
Genes: gramd4a (Dre)
Gene Ontology
Source: GO:0005789
Synonyms:
- ER membrane
Branch: cellular component
Genes: Gramd4 (Mmu)...GRAMD4 (Hsa)
Gene Ontology
Source: GO:0005739
Synonyms:
- mitochondria
Branch: cellular component
Genes: Gramd4 (Mmu)...GRAMD4 (Hsa)...Gramd4 (Rno)
Gene Ontology
Source: GO:0005783
Synonyms:
- ER
Branch: cellular component
Genes: GRAMD4 (Hsa)
Gene Ontology
Source: GO:0016020
Synonyms:
- integral component of membrane
- integral to membrane
Branch: cellular component
Genes: GRAMD4 (Hsa)...gramd4a (Dre)...Gramd4 (Rno)...gramd4b (Dre)
Gene Ontology
Source: GO:0005515
Synonyms:
- glycoprotein binding
- protein amino acid binding
Branch: molecular function
Genes: Gramd4 (Mmu)...GRAMD4 (Hsa)
(GRCh38)22:46677235C>G
(Homo sapiens)Allele/Variant
Source: rs374680937
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46677235C>G
(GRCh38)22:46668698G>A
(Homo sapiens)Allele/Variant
Source: rs377286272
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46668698G>A
(GRCh38)22:46673767A>G
(Homo sapiens)Allele/Variant
Source: rs778055597
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46673767A>G
(GRCh38)22:46676624G>C
(Homo sapiens)Allele/Variant
Source: NC_000022.11:g.46676624G>C
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46676624G>C
(GRCh38)22:46626836C>T
(Homo sapiens)Allele/Variant
Source: rs745637312
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46626836C>T
(GRCh38)22:46626936G>C
(Homo sapiens)Allele/Variant
Source: rs775569904
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46626936G>C
(GRCh38)22:46626932C>A
(Homo sapiens)Allele/Variant
Source: rs2081670498
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46626932C>A
(GRCh38)22:46626857G>C
(Homo sapiens)Allele/Variant
Source: rs142967893
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46626857G>C
(GRCh38)22:46637879G>C
(Homo sapiens)Allele/Variant
Source: NC_000022.11:g.46637879G>C
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46637879G>C
(GRCh38)22:46658259A>G
(Homo sapiens)Allele/Variant
Source: rs376982476
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46658259A>G
(GRCh38)22:46658223C>T
(Homo sapiens)Allele/Variant
Source: rs765841447
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46658223C>T
(GRCh38)22:46663842A>C
(Homo sapiens)Allele/Variant
Source: NC_000022.11:g.46663842A>C
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46663842A>C
(GRCh38)22:46664079G>A
(Homo sapiens)Allele/Variant
Source: rs945231115
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46664079G>A
(GRCh38)22:46673706G>A
(Homo sapiens)Allele/Variant
Source: rs558233933
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46673706G>A
(GRCh38)22:46663156C>G
(Homo sapiens)Allele/Variant
Source: NC_000022.11:g.46663156C>G
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46663156C>G
(GRCh38)22:46663090C>T
(Homo sapiens)Allele/Variant
Source: rs368538880
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46663090C>T
(GRCh38)22:46663096G>A
(Homo sapiens)Allele/Variant
Source: rs61552185
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46663096G>A
(GRCh38)22:46663105G>A
(Homo sapiens)Allele/Variant
Source: rs139348663
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46663105G>A
(GRCh38)22:46664104C>T
(Homo sapiens)Allele/Variant
Source: rs748060245
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46664104C>T
(GRCh38)22:46668899C>T
(Homo sapiens)Allele/Variant
Source: rs771735534
Genes: GRAMD4 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)22:46668899C>T