Version: 8.0.0
Date: Tue Jan 28 2025
1,418 results for KDSR

Kdsr

(Drosophila melanogaster)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: CG10425
Source: FB:FBgn0039304
Biotype: protein coding gene
Symbol: Kdsr (Dme)
Symbol: Kdsr
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR
Alleles: Kdsr (Dme)

KDSR

(Homo sapiens)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: short chain dehydrogenase/reductase family 35C member 1, DHSR, follicular lymphoma variant translocation 1, FVT-1, follicular variant translocation protein 1, FVT1, KDS reductase, short chain dehydrogenase/reductase family 35C, member 1, FLJ36555, SDR35C1, EKVP4, FLJ92680, 3-dehydrosphinganine reductase
Source: HGNC:4021
Biotype: protein coding gene
Symbol: KDSR (Hsa)
Symbol: KDSR
Strict Orthology Symbols: kdsr...kdsr.L...Kdsr

kdsr

(Danio rerio)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: unm_muz106, zgc:55947, 7610, fvt1
Source: ZFIN:ZDB-GENE-040426-853
Biotype: protein coding gene
Symbol: kdsr (Dre)
Symbol: kdsr
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR

Kdsr

(Rattus norvegicus)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: follicular lymphoma variant translocation 1, Fvt1, LOC360833
Source: RGD:1307775
Biotype: protein coding gene
Symbol: Kdsr (Rno)
Symbol: Kdsr
Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase); PARTICIPATES IN Fabry disease pathway
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR

Kdsr

(Mus musculus)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: RIKEN cDNA 9430079B08 gene, follicular lymphoma variant translocation 1, 9430079B08Rik, RIKEN cDNA 6330410P18 gene, Fvt1, 6330410P18Rik
Source: MGI:1918000
Biotype: protein coding gene
Symbol: Kdsr (Mmu)
Symbol: Kdsr
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR
Alleles: Kdsr (Mmu)

kdsr

(Xenopus tropicalis)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: 3-ketodihydrosphingosine reductase, kdsr
Source: Xenbase:XB-GENE-985089
Biotype: gene
Symbol: kdsr (Xtr)
Symbol: kdsr
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Synonyms: kdsr...kdsr
Strict Orthology Symbols: KDSR

KDSR-DT

(Homo sapiens)
Gene
Name: KDSR divergent transcript
Synonyms: Not Available
Source: HGNC:55299
Biotype: ncRNA gene
Symbol: KDSR-DT (Hsa)
Symbol: KDSR-DT

kdsr.L

(Xenopus laevis)
Gene
Name: 3-ketodihydrosphingosine reductase
Synonyms: 3-ketodihydrosphingosine reductase, kdsr.L
Source: Xenbase:XB-GENE-985095
Biotype: gene
Symbol: kdsr.L (Xla)
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR
Symbol: kdsr.L

KdsrHMJ22636

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393637
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrHMJ22636

KdsrTOE.GS01408

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0338407
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrTOE.GS01408

KdsrGD269

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0199024
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrGD269

KdsrGt(OST202531)Lex

(Mus musculus)
Allele/Variant
Source: MGI:4230018
Genes: Kdsr (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Mmu)
Genes: Kdsr (Mmu)
Symbol: KdsrGt(OST202531)Lex

KdsrHMC05512

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0321798
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrHMC05512

KdsrTKO.GS00730

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0335767
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrTKO.GS00730

KdsrKK100720

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0258803
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Construct Knockdown Component: Kdsr (Dme)
Symbol: KdsrKK100720

kdsrmuz106/muz106 (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-2413
Synonyms: Not Available
Symbol: kdsr (AB) (Dre)
Genes: kdsr (Dre)
Name: kdsr (AB)

kdsrmuz106/muz106; sphk2wcm2/wcm2 (AB/TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-191121-8
Synonyms: Not Available
Symbol: kdsr; sphk2 (AB/TU) (Dre)
Genes: kdsr (Dre)
Name: kdsr; sphk2 (AB/TU)

kdsrmuz106/+ (AB/TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-191204-1
Synonyms: Not Available
Symbol: kdsr (AB/TU) (Dre)
Genes: kdsr (Dre)
Name: kdsr (AB/TU)

kdsrmuz106/muz106 (AB/TU)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-191121-7
Synonyms: Not Available
Symbol: kdsr (AB/TU) (Dre)
Genes: kdsr (Dre)
Name: kdsr (AB/TU)

KdsrDG20502

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0218883
Genes: Kdsr (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Kdsr (Dme)
Genes: Kdsr (Dme)
Symbol: KdsrDG20502

TSC10

(Saccharomyces cerevisiae)
Gene
Name: Temperature-sensitive Suppressors of Csg2 mutants
Synonyms: YBR265W
Source: SGD:S000000469
Biotype: protein coding gene
Gene Synopsis: droplets; member of short chain dehydrogenase/reductase protein family; mutations in human homolog KDSR
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR

Y37E11AM.3

(Caenorhabditis elegans)
Gene
Name: 3-dehydrosphinganine reductase
Synonyms: Y37E11AL.a, CELE_Y37E11AM.3
Source: WB:WBGene00021367
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human KDSR (3-ketodihydrosphingosine reductase).
Strict Orthology Symbols: KDSR

zgc:158689

(Danio rerio)
Gene
Name: zgc:158689
Synonyms: Not Available
Source: ZFIN:ZDB-GENE-070112-1902
Biotype: protein coding gene
Strict Orthology Symbols: kdsr

Y37E11AM.4

(Caenorhabditis elegans)
Gene
Name: Ribonuclease P
Synonyms: CELE_Y37E11AM.4
Source: WB:WBGene00302986
Biotype: protein coding gene
Strict Orthology Symbols: kdsr

erythrokeratodermia variabilis et progressiva 4

Disease
Source: DOID:0080250
Definition: An erythrokeratodermia variabilis that is characterized by severe lesions of thick scaly skin on the face and genitals, as well as thickened, red, and scaly skin on the hands and feet and that has_material_basis_in compound heterozygous mutation in the KDSR gene on chromosome 18q21.
Genes: kdsr (Xtr)...KDSR (Hsa)...Kdsr (Dme)...Kdsr (Mmu)...Kdsr (Rno)

3-dehydrosphinganine reductase activity

Gene Ontology
Source: GO:0047560
Synonyms:
  • 3-ketosphinganine reductase activity
  • 3-oxosphinganine reductase activity
Branch: molecular function
Genes: KDSR (Hsa)...Kdsr (Dme)...Kdsr (Mmu)...Kdsr (Rno)...kdsr (Dre)

3-keto-sphinganine metabolic process

Gene Ontology
Source: GO:0006666
Synonyms:
  • 3-keto-dihydrosphingosine metabolic process
  • 3-keto-dihydrosphingosine metabolism
Branch: biological process
Genes: KDSR (Hsa)...Kdsr (Dme)...Kdsr (Mmu)...Kdsr (Rno)...kdsr (Dre)

IRSp53

(Drosophila melanogaster)
Gene
Name: Insulin receptor substrate 53 kDa
Synonyms: CG7624, anon-WO0118547.199, CG32082, IRS
Source: FB:FBgn0052082
Biotype: protein coding gene
Strict Orthology Symbols: kdsr

follicular lymphoma

Disease
Source: DOID:0050873
Definition: A B-cell lymphoma that is characterized as an indolent non-Hodgkin's lymphoma and has_material_basis_in follicle center B-cells (centrocytes and centroblasts).
Genes: kdsr (Xtr)...kdsr.L (Xla)...kdsr (Dre)...KDSR (Hsa)...Kdsr (Dme)

la2Tg + MO1-kdsr

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-200130-33
Synonyms: Not Available
Genes: kdsr (Dre)
Name: la2Tg + MO1-kdsr

NADPH binding

Gene Ontology
Source: GO:0070402
Synonyms:
  • NADP (reduced) binding
  • reduced NADP binding
Branch: molecular function
Genes: kdsr (Dre)...KDSR (Hsa)...Kdsr (Mmu)

sphingolipid mediated signaling pathway

Gene Ontology
Source: GO:0090520
Synonyms:
  • ceramide 1-phosphate signaling pathway
  • ceramide signaling pathway
Branch: biological process
Genes: kdsr (Dre)

sphingolipid biosynthetic process

Gene Ontology
Source: GO:0030148
Synonyms:
  • sphingolipid anabolism
  • sphingolipid biosynthesis
Branch: biological process
Genes: kdsr (Dre)...Kdsr (Mmu)...Kdsr (Rno)...KDSR (Hsa)...Kdsr (Dme)

liver disease

Disease
Source: DOID:409
Definition: Not Available
Genes: kdsr (Dre)...Kdsr (Mmu)...kdsr (Xtr)...Kdsr (Rno)...KDSR (Hsa)

thrombocytopenia

Disease
Source: DOID:1588
Definition: A blood platelet disease that is characterized by low a platelet count in the blood.
Genes: kdsr (Dre)...Kdsr (Mmu)...kdsr (Xtr)...Kdsr (Rno)...KDSR (Hsa)

intracellular sphingolipid homeostasis

Gene Ontology
Source: GO:0090156
Synonyms:
  • cellular sphingolipid homeostasis
Branch: biological process
Genes: kdsr (Dre)

sphingomyelin biosynthetic process

Gene Ontology
Source: GO:0006686
Synonyms:
  • sphingomyelin anabolism
  • sphingomyelin biosynthesis
Branch: biological process
Genes: kdsr (Dre)

platelet formation

Gene Ontology
Source: GO:0030220
Synonyms:
  • platelet extrusion
Branch: biological process
Genes: kdsr (Dre)

sphingolipid metabolic process

Gene Ontology
Source: GO:0006665
Synonyms:
  • sphingolipid metabolism
Branch: biological process
Genes: KDSR (Hsa)

endoplasmic reticulum membrane

Gene Ontology
Source: GO:0005789
Synonyms:
  • ER membrane
Branch: cellular component
Genes: kdsr (Dre)...Kdsr (Rno)...KDSR (Hsa)...Kdsr (Dme)...Kdsr (Mmu)

muz122

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-190730-5
Genes: kdsr (Dre)
Synonyms: Not Available
Variant Type: delins
Molecular Consequence: stop_gained, protein_altering_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kdsr (Dre)

sa25779

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-12640
Genes: kdsr (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: kdsr (Dre)

muz106

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-150723-12
Genes: kdsr (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: liver disease
Variant Name: Not Available
Genes: kdsr (Dre)

(GRCh38)18:63350953C>T

(Homo sapiens)
Allele/Variant
Source: rs751571336
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63350953C>T

(GRCh38)18:63350985A>G

(Homo sapiens)
Allele/Variant
Source: rs201014559
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63350985A>G

(GRCh38)18:63355225A>T

(Homo sapiens)
Allele/Variant
Source: rs761321465
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63355225A>T

(GRCh38)18:63338803G>A

(Homo sapiens)
Allele/Variant
Source: rs749446295
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63338803G>A

(GRCh38)18:63355523T>G

(Homo sapiens)
Allele/Variant
Source: rs143245434
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63355523T>G

(GRCh38)18:63335257C>T

(Homo sapiens)
Allele/Variant
Source: rs752611378
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, non_coding_transcript_exon_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63335257C>T

(GRCh38)18:63338903T>A

(Homo sapiens)
Allele/Variant
Source: rs1568276547
Genes: KDSR (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)18:63338903T>A