Version: 8.2.0Date: Wed Aug 27 2025
Category
RT1-Db2
(Rattus norvegicus)Gene
Name: RT1 class II, locus Db2
Synonyms: RT1 class II, locus Db2 (mapped), MHC class II beta chain, Db2, RT1-Db2_mapped
Source: RGD:1595922
Biotype: protein coding gene
Symbol: RT1-Db2 (Rno)
Symbol: RT1-Db2
HLA-DRB3
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 3
Synonyms: MHC class II HLA-DR beta 3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, MHC Class II antigen, HLA-DRB3*, HLA class II histocompatibility antigen, DR beta 3 chain, DR7, HLA-DR52, MHC class II antigen DRB3, DRw10, SS1, MHC class II antigen DR beta 3 chain, major histocompatibility complex, class II, DRB3, MGC117330, HLA-DPB1, human leucocyte antigen DRB3, HLA-DR1B, DRB1, MHC class II DR beta chain, HLA DRB3, HLA-DR3B, HLA-DRB1, HLA-DRB, DRB3
Source: HGNC:4951
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
HLA-DRB5
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 5
Synonyms: MHC HLA-DR-beta cell surface glycoprotein, DRB5, MHC HLA-DR-beta chain, HLA-DRB5*, FLJ76359, MHC class II antigen DRB1*9, DR9, HLA class II histocompatibility antigen, DR-5 beta chain, MHC class II antigen DRB5, HLA class II histocompatibility antigen, DRB1-9 beta chain, human leucocyte antigen DRB5, MHC class II HLA beta chain, MHC class I antigen, HLA class II histocompatibility antigen, DR beta 5 chain, DR-9, dw2, leukocyte antigen class II, HLA-DRB, DR beta-5, DR2-beta-2
Source: HGNC:4953
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
HLA-DRB4
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 4
Synonyms: MHC class2 antigen, MHC class II HLA-DR-beta-7, MHC class II antigen DRB1*4, leucocyte antigen DRB1, MHC class II antigen HLA-DR-beta, leukocyte antigen, DR12, DR13, DR14, HLA class II histocompatibility antigen, DRB1-4 beta chain, MHC HLA DR-beta chain, DR-4, DRB1 transplantation antigen, HLA class II histocompatibility antigen, DR beta 4 chain, HLA class II histocompatibility antigen, DRB1-12 beta chain, HLA-DR4B, DRB4, class II histocompatibility antigen HLA DR alpha, beta1-0307, DR-12, DR-13, HLA-DRB4*, DR-14, DR4, MHC class I antigen DRB1*4, MHC class I antigen DRB1*12, major histocompatibility complex, class II, DR beta 1, MHC class II antigen HLA-DRB1, MHC class II antigen DRB4, MHC class II antigen DRB1*12, MHC class II antigen DRB1*13, MHC class II antigen DRB1*14, human leucocyte antigen DRB4, HLA-DRB
Source: HGNC:4952
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
HLA-DRB1
(Homo sapiens)Gene
Name: major histocompatibility complex, class II, DR beta 1
Synonyms: MHC class II HLA-DRw10-beta, HLA-DRB1*, leucocyte antigen DRB1, DW2.2/DR2.2, FLJ76359, HLA-DR-beta 1, leucocyte antigen DR beta 1 chain, MHC class II antigen, major histocompatibility complex, class II, DR beta 1 precursor, DRw8, SS1, DR16, DR-8, MHC class II HLA-DR beta 1 chain, lymphocyte antigen DRB1, DRB1, DR-16, HLA class II histocompatibility antigen, DR-1 beta chain, DR1, MHC class II antigen HLA-DR13, DR5, FLJ75017, HLA class II antigen beta chain, DR8, DRw11, DRw10, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1, HLA-DR1B, HLA-DRB
Source: HGNC:4948
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
H2-Eb2
(Mus musculus)Gene
Name: histocompatibility 2, class II antigen E beta2
Synonyms: Ia-5, RIKEN cDNA A130038H09 gene, Db2, H-2Eb2, I region-associated antigen 5, Ia5, A130038H09Rik
Source: MGI:95902
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
mhc2dbb
(Danio rerio)Gene
Name: major histocompatibility complex class II DBB gene
Synonyms: zgc:153067, si:dz241h12.1, DBB, mhc2d18b, si:busm1-241h12.1
Source: ZFIN:ZDB-GENE-010112-2
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
mhc2dab
(Danio rerio)Gene
Name: major histocompatibility complex class II DAB gene
Synonyms: zgc:152682, Brre-DAB1*04, mhc2d8.37b3, DAB, dab101, dab201, dab301, zgc:158870, si:dkeyp-2h4.1, MHC Brre-DAB4, mhciidab, dab401, dab402, zgc:123077
Source: ZFIN:ZDB-GENE-980526-200
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
mhc2d8.45b1
(Danio rerio)Gene
Name: major histocompatibility complex class II d8.45b1
Synonyms: si:dz228j01.6, zgc:123114, si:busm1-228j01.6, MHC class II
Source: ZFIN:ZDB-GENE-030616-396
Biotype: protein coding gene
Strict Orthology Symbols: RT1-Db2
mhc2-dab
(Xenopus tropicalis)Gene
Name: major histocompatibility complex, class II, DA beta
Synonyms: dab, LOC100145508, major histocompatibility complex, class II, DA beta, LOC100133583, XB5827395, mhc2-dab
Source: Xenbase:XB-GENE-5827396
Biotype: gene
Strict Orthology Symbols: RT1-Db2
Disease
Source: DOID:0060532
Definition: An allergic disease that is triggered by latex.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12029
Definition: A panuveitis that is characterized by bilateral diffuse intraocular inflammation following penetrating trauma to an eye, has_symptom blurry vision, watering, pain, and photophobia.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:13404
Definition: A sarcoidosis that is characterized by unilateral facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever, and develops_from a type IV hypersensitivity reaction with noncaseating granulomatous infiltration of especially the parotid glands which compresses the facial nerve.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1395
Definition: A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria.
Genes: RT1-Db2 (Rno)
Source: DOID:0050168
Definition: An autoimmune polyendocrine syndrome that is characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs. It is more heterogeneous and has not been linked to one gene.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12148
Definition: An echinococcosis that is caused by the larvae of Echinococcus multilocularis affecting the liver as a slow growing, destructive tumor, with abdominal pain, biliary obstruction, and occasionally metastatic lesions into the lungs and brain.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1495
Definition: An echinococcosis that is caused by the larvae of Echinococcus granulosus. Hepatic involvement can result in abdominal pain, a mass in the hepatic area, and biliary duct obstruction. Pulmonary involvement can produce chest pain, cough, and hemoptysis. Rupture of the cysts produce fever, urticaria, eosinophilia, and anaphylactic shock, as well as cyst dissemination. Brain, bone, heart can also be infected.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1340
Definition: A congenital hypoplastic anemia that is characterized by a normocytic normochromic anemia with severe reticulocytopenia and marked reduction or absence of erythroid precursors from the bone marrow.
Genes: RT1-Db2 (Rno)
Source: DOID:401
Definition: A tuberculosis that is resistant to isoniazid and rifampicin, the two most powerful first-line anti-TB drugs.
Genes: RT1-Db2 (Rno)
Source: DOID:13166
Definition: An aspergillosis that involves an allergic reaction due to the spores of Aspergillus moulds (A. fumigatus), which colonizes the mucus in the airways causing inflammation. The disease has symptom cough, has symptom wheezing and has symptom fever.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:11656
Definition: A pemphigoid that is characterized by skin lesions and scaring and located_in mucous membranes and located_in skin.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1586
Definition: A connective tissue disease that develops from an antecedent Group A Streptococcal pharyngeal infection and has_symptom carditis, has_symptom polyarthritis, has_symptom chorea, has_symptom erythema marginatum, has_symptom subcutaneous nodules, has_symptom arthralgia, has_symptom prolonged PR interval, and/or has_symptom fever.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:10983
Definition: A syndrome disease that is characterized by glomerulonephritis, endstage kidney disease, and hearing loss.
Genes: RT1-Db2 (Rno)
Source: DOID:14040
Definition: An autoimmune disease of endocrine system characterized by abnormal functioning of the immune system that causes auto-reactivity against endocrine organs.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12859
Definition: A movement disease characterized by brief, semi-directed, irregular movements that not repetitive or rhythmic, but appear to flow from one muscle to the next.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:13258
Definition: A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia.
Genes: RT1-Db2 (Rno)
Source: DOID:639
Definition: An encephalomyelitis characterized by inflammation located in brain and located in spinal cord that damages myelin. It usually occurs after viral infection, but also following vaccination, bacterial or parasitic infection.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12297
Definition: An autoimmune disease that is caused by T helper cell mediated autoimmune attack of melanocytes resulting in inflammation of the inside of the eye, whitening of hair, skin pigment loss, and meningitis.
Genes: RT1-Db2 (Rno)
Source: DOID:3492
Definition: A collagen disease that is considered an overlap of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis with very high titers of circulating antinuclear antibody to a ribonucleoprotein antigen.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:13774
Definition: An adrenal cortical hypofunction that is characterized by insufficient steroid hormone production by the adrenal glands.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12662
Definition: A primary systemic mycosis that results_in systemic fungal infection located_in mucosa, located_in lymph nodes, located_in bone, located_in skin or located_in lungs, has_material_basis_in Paracoccidioides brasiliensis.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:8986
Definition: A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work.
Genes: RT1-Db2 (Rno)
Source: DOID:11266
Definition: A viral infectious disease that is a hemorrhagic fever, located in kidney, has_material_basis_in Orthohantavirus dobravaense, Orthohantavirus hantanense, Orthohantavirus puumalaense, or Orthohantavirus seoulense, which are carried and transmitted by rodents. The infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom proteinuria, and has symptom renal failure.
Genes: RT1-Db2 (Rno)
Gene Ontology
Source: GO:0002504
Synonyms:
- peptide or polysaccharide antigen processing and presentation of via MHC class II
Branch: biological process
Genes: RT1-Db2 (Rno)
Gene Ontology
Source: GO:0023026
Synonyms: Not Available
Branch: molecular function
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:9415
Definition: An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:9182
Definition: An autoimmune disease of skin and connective tissue that is characterized by blistering of the outer layer of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals), causing lesions and blisters that are easily ruptured.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:8869
Definition: A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis).
Genes: RT1-Db2 (Rno)
Source: GO:0002503
Synonyms: Not Available
Branch: biological process
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:8568
Definition: A viral infectious disease that results in inflammation, located in pharynx, has_material_basis_in Human herpesvirus 4 (Lymphocryptovirus humangamma4) and has symptom fever, has symptom fatigue, has symptom lymphadenopathy, and has symptom splenomegaly.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1389
Definition: A peripheral system disease that is characterized by damage affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, pins-and-needles, and burning pain.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:2988
Definition: An autoimmune disease that is characterized by recurrent venous or arterial thrombosis and/or fetal losses associated with characteristic elevated levels of antibodies directed against membrane anionic phospholipids (anticardiolipin).
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1024
Definition: A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has_symptom skin lesions, has_symptom sensory loss, has_symptom motor loss and has_symptom eye damage.
Genes: RT1-Db2 (Rno)
Gene Ontology
Source: GO:0042613
Synonyms: Not Available
Branch: cellular component
Genes: RT1-Db2 (Rno)
Source: DOID:0050784
Definition: A multiple sclerosis that is characterized by steady worsening of neurologic functioning, without any distinct relapses or periods of remission. The rate of progression may vary over time, with occasional plateaus or temporary improvements, but the progression is continuous.
Genes: RT1-Db2 (Rno)
Source: DOID:0080822
Definition: An intrinsic asthma that is characterized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs.
Genes: RT1-Db2 (Rno)
Gene Ontology
Source: GO:0050778
Synonyms:
- stimulation of immune response
- up regulation of immune response
Branch: biological process
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:12140
Definition: A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Genes: RT1-Db2 (Rno)
Disease
Source: DOID:1245
Definition: A female reproductive organ cancer that is located_in the vulva.
Genes: RT1-Db2 (Rno)