Version: 8.0.0Date: Tue Jan 28 2025
Category
Aldh6a1
(Mus musculus)Gene
Name: aldehyde dehydrogenase family 6, subfamily A1
Synonyms: 1110038I05Rik, AI314632, RIKEN cDNA 1110038I05 gene, expressed sequence AI314632, Mmsdh, methylmalonate-semialdehyde dehydrogenase, MGC:37325
Source: MGI:1915077
Biotype: protein coding gene
Symbol: Aldh6a1 (Mmu)
Symbol: Aldh6a1
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
Alleles: Aldh6a1
ALDH6A1
(Homo sapiens)Gene
Name: aldehyde dehydrogenase 6 family member A1
Synonyms: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, aldehyde dehydrogenase family 6 member A1, mitochondrial acylating methylmalonate-semialdehyde dehydrogenase, testicular tissue protein Li 122, malonate-semialdehyde dehydrogenase, MMSDH, malonate-semialdehyde dehydrogenase (acetylating), methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSADHA, MGC40271, aldehyde dehydrogenase 6 family, member A1
Source: HGNC:7179
Biotype: protein coding gene
Symbol: ALDH6A1 (Hsa)
Symbol: ALDH6A1
Strict Orthology Symbols: aldh6a1
Aldh6a1
(Rattus norvegicus)Gene
Name: aldehyde dehydrogenase 6 family, member A1
Synonyms: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, aldehyde dehydrogenase family 6 member A1, methylmalonate semialdehyde dehydrogenase gene, malonate-semialdehyde dehydrogenase, Mmsdh, methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial, aldehyde dehydrogenase family 6, subfamily A1, methylmalonate semialdehyde dehydrogenase
Source: RGD:621556
Biotype: protein coding gene
Symbol: Aldh6a1 (Rno)
Symbol: Aldh6a1
Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1); PARTICIPATES IN 3-hydroxy-3
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
aldh6a1
(Danio rerio)Gene
Name: aldehyde dehydrogenase 6 family, member A1
Synonyms: mitochondrial acylating methylmalonate-semialdehyde dehydrogenase, cb850, wu:fb03a04, zgc:92082
Source: ZFIN:ZDB-GENE-030131-9192
Biotype: protein coding gene
Symbol: aldh6a1 (Dre)
Symbol: aldh6a1
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
aldh6a1
(Xenopus tropicalis)Gene
Name: aldehyde dehydrogenase 6 family member A1
Synonyms: aldehyde dehydrogenase 6 family member A1, aldh6a1
Source: Xenbase:XB-GENE-1006692
Biotype: gene
Symbol: aldh6a1
Symbol: aldh6a1 (Xtr)
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Synonyms: aldh6a1...aldh6a1...aldh6a1
Strict Orthology Symbols: aldh6a1
aldh6a1.L
(Xenopus laevis)Gene
Name: aldehyde dehydrogenase 6 family member A1
Synonyms: aldehyde dehydrogenase 6 family member A1, aldh6a1.L
Source: Xenbase:XB-GENE-1006695
Biotype: gene
Symbol: aldh6a1.L (Xla)
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
Symbol: aldh6a1.L
aldh6a1.S
(Xenopus laevis)Gene
Name: aldehyde dehydrogenase 6 family member A1
Synonyms: aldehyde dehydrogenase 6 family member A1, aldh6a1.S
Source: Xenbase:XB-GENE-17343191
Biotype: gene
Symbol: aldh6a1.S (Xla)
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
Symbol: aldh6a1.S
Aldh6a1em1Cya
(Mus musculus)Allele/Variant
Source: MGI:7582298
Genes: Aldh6a1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aldh6a1
Genes: Aldh6a1 (Mmu)
Symbol: Aldh6a1em1Cya
Aldh6a1em1(IMPC)Bay
(Mus musculus)Allele/Variant
Source: MGI:7549279
Genes: Aldh6a1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Aldh6a1
Genes: Aldh6a1 (Mmu)
Symbol: Aldh6a1em1(IMPC)Bay
CG17896
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: EG:171D11.1, 153323_at
Source: FB:FBgn0023537
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
alh-8
(Caenorhabditis elegans)Gene
Name: ALdehyde deHydrogenase 8
Synonyms: F13D12.4, CELE_F13D12.4
Source: WB:WBGene00000114
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human ALDH6A1 (aldehyde dehydrogenase 6 family member A1).
Strict Orthology Symbols: aldh6a1
Source: GO:0018478
Synonyms:
- 3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)
- malonic semialdehyde oxidative decarboxylase activity
Branch: molecular function
Genes: ALDH6A1 (Hsa)...Aldh6a1 (Mmu)...Aldh6a1 (Rno)
Gene Ontology
Source: GO:0006573
Synonyms:
- valine metabolism
Branch: biological process
Genes: ALDH6A1 (Hsa)...Aldh6a1 (Mmu)...Aldh6a1 (Rno)
Source: GO:0004491
Synonyms:
- MMSA dehydrogenase activity
- MSDH activity
Branch: molecular function
Genes: aldh6a1 (Dre)...ALDH6A1 (Hsa)...Aldh6a1 (Mmu)...Aldh6a1 (Rno)
Gene Ontology
Source: GO:0019859
Synonyms:
- thymine metabolism
Branch: biological process
Genes: ALDH6A1 (Hsa)...Aldh6a1 (Mmu)...Aldh6a1 (Rno)
Gene Ontology
Source: GO:0006210
Synonyms:
- thymine breakdown
- thymine catabolism
Branch: biological process
Genes: aldh6a1 (Dre)...ALDH6A1 (Hsa)...Aldh6a1 (Mmu)...Aldh6a1 (Rno)
WT + MO1-aldh6a1
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-20102
Synonyms: Not Available
Genes: aldh6a1 (Dre)
Name: WT + MO1-aldh6a1
Gene Ontology
Source: GO:0019484
Synonyms:
- beta-alanine breakdown
- beta-alanine catabolism
Branch: biological process
Genes: Aldh6a1 (Mmu)...Aldh6a1 (Rno)
Gene Ontology
Source: GO:0006574
Synonyms:
- valine breakdown
- valine catabolism
Branch: biological process
Genes: ALDH6A1 (Hsa)...Aldh6a1 (Rno)...aldh6a1 (Dre)...Aldh6a1 (Mmu)
Gene Ontology
Source: GO:0016790
Synonyms:
- thiolesterase activity
Branch: molecular function
Genes: Aldh6a1 (Rno)...Aldh6a1 (Mmu)
Gene Ontology
Source: GO:0050873
Synonyms:
- brown adipocyte cell differentiation
- brown adipocyte differentiation
Branch: biological process
Genes: Aldh6a1 (Mmu)...ALDH6A1 (Hsa)...Aldh6a1 (Rno)
Gene Ontology
Source: GO:0009083
Synonyms:
- branched chain family amino acid breakdown
- branched chain family amino acid catabolic process
Branch: biological process
Genes: ALDH6A1 (Hsa)
Gene Ontology
Source: GO:0016620
Synonyms: Not Available
Branch: molecular function
Genes: aldh6a1 (Dre)
Gene Ontology
Source: GO:0016491
Synonyms:
- oxidoreductase activity, acting on other substrates
- redox activity
Branch: molecular function
Genes: aldh6a1 (Dre)...ALDH6A1 (Hsa)
Gene Ontology
Source: GO:0005759
Synonyms:
- mitochondrial lumen
- mitochondrial stroma
Branch: cellular component
Genes: ALDH6A1 (Hsa)
Gene Ontology
Source: GO:0005739
Synonyms:
- mitochondria
Branch: cellular component
Genes: Aldh6a1 (Rno)...aldh6a1 (Dre)...Aldh6a1 (Mmu)...ALDH6A1 (Hsa)
sa36509
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-4677
Genes: aldh6a1 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: aldh6a1 (Dre)
Gene Ontology
Source: GO:0005654
Synonyms: Not Available
Branch: cellular component
Genes: Aldh6a1 (Rno)...Aldh6a1 (Mmu)...ALDH6A1 (Hsa)
Gene Ontology
Source: GO:0003723
Synonyms:
- base pairing with RNA
- poly(A) RNA binding
Branch: molecular function
Genes: ALDH6A1 (Hsa)
(GRCh38)14:74084453T>G
(Homo sapiens)Allele/Variant
Source: rs886050733
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084453T>G
(GRCh38)14:74084401C>T
(Homo sapiens)Allele/Variant
Source: rs749971767
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084401C>T
(GRCh38)14:74084356C>T
(Homo sapiens)Allele/Variant
Source: rs768586669
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084356C>T
(GRCh38)14:74084389C>A
(Homo sapiens)Allele/Variant
Source: rs948820344
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084389C>A
(GRCh38)14:74084355T>G
(Homo sapiens)Allele/Variant
Source: rs147854047
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084355T>G
(GRCh38)14:74084351A>T
(Homo sapiens)Allele/Variant
Source: rs552026685
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74084351A>T
(GRCh38)14:74084394T>C
(Homo sapiens)Allele/Variant
Source: rs74062580
Genes: ALDH6A1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, start_lost
Diseases: Not Available
Variant Name: (GRCh38)14:74084394T>C
(GRCh38)14:74058281C>T
(Homo sapiens)Allele/Variant
Source: rs112689182
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74058281C>T
(GRCh38)14:74058344C>T
(Homo sapiens)Allele/Variant
Source: rs76665287
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74058344C>T
(GRCh38)14:74060545A>G
(Homo sapiens)Allele/Variant
Source: rs2060316331
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74060545A>G
(GRCh38)14:74068964C>T
(Homo sapiens)Allele/Variant
Source: rs761850051
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74068964C>T
(GRCh38)14:74071235G>T
(Homo sapiens)Allele/Variant
Source: rs145024996
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74071235G>T
(GRCh38)14:74071244A>C
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.74071244A>C
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74071244A>C
(GRCh38)14:74064931A>G
(Homo sapiens)Allele/Variant
Source: rs781755957
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74064931A>G
(GRCh38)14:74064938C>T
(Homo sapiens)Allele/Variant
Source: rs376470740
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74064938C>T
(GRCh38)14:74067372T>C
(Homo sapiens)Allele/Variant
Source: NC_000014.9:g.74067372T>C
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74067372T>C
(GRCh38)14:74067400T>C
(Homo sapiens)Allele/Variant
Source: rs1280262132
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74067400T>C
(GRCh38)14:74067425G>A
(Homo sapiens)Allele/Variant
Source: rs1595118923
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74067425G>A
(GRCh38)14:74067474G>A
(Homo sapiens)Allele/Variant
Source: rs764477811
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74067474G>A
(GRCh38)14:74067566C>A
(Homo sapiens)Allele/Variant
Source: rs1328953759
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74067566C>A
(GRCh38)14:74071182T>G
(Homo sapiens)Allele/Variant
Source: rs2072293
Genes: ALDH6A1 (Hsa), BBOF1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:74071182T>G