Version: 8.1.0Date: Fri Apr 18 2025
Category
arx-7
(Caenorhabditis elegans)Gene
Name: ARp2/3 compleX component 7
Synonyms: CELE_M01B12.3, M01B12.3, M01B12.d
Source: WB:WBGene00000205
Biotype: protein coding gene
Symbol: arx-7 (Cel)
Symbol: arx-7
Gene Synopsis: arx-7 also called as p16Arc encodes a subunit of the actin related protein of the conserved Arp2/3 complex..., with 60% amino acid similarity with the homologous genes from human (OMIM: 604227); arx-7 is an essential...Mutations in arx-7 cause PDE axon guidance defects; arx-7 mutants affect PQR growth cone morphology and...filopodia formation; arx-7 acts cell-autonomously in PQR filopodia regulation.
Cross References: WB:arx-7...arx-7...arx-7
ARPC5
(Homo sapiens)Gene
Name: actin related protein 2/3 complex subunit 5
Synonyms: actin related protein 2/3 complex subunit 5, 16kDa, MGC88523, dJ127C7.3, actin related protein 2/3 complex, subunit 5, 16kDa, Arp2/3 protein complex subunit p16, arp2/3 complex 16 kDa subunit, ARC16, IMD113, actin-related protein 2/3 complex subunit 5, p16-Arc
Source: HGNC:708
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
ARPC5L
(Homo sapiens)Gene
Name: actin related protein 2/3 complex subunit 5 like
Synonyms: actin-related protein 2/3 complex subunit 5-like protein, MGC3038, ARC16-2, actin related protein 2/3 complex, subunit 5-like, arp2/3 complex 16 kDa subunit 2, actin related protein 2/3 complex subunit 5-like
Source: HGNC:23366
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
arpc5lb
(Danio rerio)Gene
Name: actin related protein 2/3 complex, subunit 5-like, b
Synonyms: si:dkeyp-15f12.2
Source: ZFIN:ZDB-GENE-060531-161
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
ARC15
(Saccharomyces cerevisiae)Gene
Name: ARp2/3 Complex subunit
Synonyms: YIL062C
Source: SGD:S000001324
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Arpc5
(Drosophila melanogaster)Gene
Name: Actin-related protein 2/3 complex, subunit 5
Synonyms: p16, P16-ARC, ArpC5, Arpc5, CG9881, ARPC5, p16-arc, p16-ARC
Source: FB:FBgn0031437
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Arpc5l
(Mus musculus)Gene
Name: actin related protein 2/3 complex, subunit 5-like
Synonyms: RGD1560362, AW555592, expressed sequence AW555592, Arpc5l2, AW742746, Arpc5l1, RIKEN cDNA 2010015J01 gene, ARC16-2, AI852867, expressed sequence AI852867, 2010015J01Rik, expressed sequence AW742746
Source: MGI:1921442
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Arpc5
(Rattus norvegicus)Gene
Name: actin related protein 2/3 complex, subunit 5
Synonyms: MGC116419, LOC360854, arp2/3 complex 16 kDa subunit, actin-related protein 2/3 complex subunit 5, p16-ARC
Source: RGD:1311791
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Arpc5l
(Rattus norvegicus)Gene
Name: actin related protein 2/3 complex, subunit 5-like
Synonyms: actin-related protein 2/3 complex subunit 5-like protein, Arpc5l1, ARC16-2, actin related protein 2/3 complex, subunit 5-like 1, LOC296710, arp2/3 complex 16 kDa subunit 2, MGC112865
Source: RGD:1308867
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
arpc5b
(Danio rerio)Gene
Name: actin related protein 2/3 complex, subunit 5B
Synonyms: Not Available
Source: ZFIN:ZDB-GENE-040120-7
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
arpc5a
(Danio rerio)Gene
Name: actin related protein 2/3 complex, subunit 5A
Synonyms: wu:fb12b05, fb09c07, fb12b05, fc56c07, arpc5, wu:fb09c07, wu:fc56c07
Source: ZFIN:ZDB-GENE-030131-8448
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Arpc5
(Mus musculus)Gene
Name: actin related protein 2/3 complex, subunit 5
Synonyms: RIKEN cDNA 5830443F10 gene, 5830443F10Rik, p16-Arc
Source: MGI:1915021
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
arpc5la
(Danio rerio)Gene
Name: actin related protein 2/3 complex, subunit 5-like, a
Synonyms: zgc:77408, zgc:65881, arpc5l
Source: ZFIN:ZDB-GENE-040426-1453
Biotype: protein coding gene
Strict Orthology Symbols: arx-7
Disease
Source: DOID:0061096
Definition: A primary immunodeficiency disease that is characterized recurrent infections and features of autoimmunity and autoinflammation, such as hemolytic anemia, thrombocytopenia, hepatosplenomegaly, leukocytosis, neutrophilia, and elevated acute phase reactants and that has_material_basis_in homozygous mutation in the ARPC5 gene on chromosome 1q25. The disorder results from dysregulation of the actin cytoskeleton that affects certain cell lineages.
Genes: arx-7 (Cel)
arpc5
(Xenopus tropicalis)Gene
Name: actin related protein 2/3 complex subunit 5
Synonyms: actin related protein 2/3 complex subunit 5, arpc5
Source: Xenbase:XB-GENE-494089
Biotype: gene
Strict Orthology Symbols: arx-7
arpc5l
(Xenopus tropicalis)Gene
Name: actin related protein 2/3 complex subunit 5-like
Synonyms: arpc5l, MGC80296, actin related protein 2/3 complex subunit 5-like
Source: Xenbase:XB-GENE-490524
Biotype: gene
Strict Orthology Symbols: arx-7
Gene Ontology
Source: GO:0010631
Synonyms: Not Available
Branch: biological process
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0016331
Synonyms: Not Available
Branch: biological process
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0005885
Synonyms: Not Available
Branch: cellular component
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0034314
Synonyms:
- actin filament branch nucleation
- branched actin filament nucleation
Branch: biological process
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0030833
Synonyms:
- regulation of actin polymerization
Branch: biological process
Genes: arx-7 (Cel)
Disease
Source: DOID:0050328
Definition: A hypothyroidism that is present at birth.
Genes: arx-7 (Cel)
Disease
Source: DOID:1508
Definition: An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons.
Genes: arx-7 (Cel)
Disease
Source: DOID:3907
Definition: A non-small cell lung carcinoma that has_material_basis_in the squamous cell.
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0015629
Synonyms: Not Available
Branch: cellular component
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0051015
Synonyms:
- F-actin binding
- actin cross-linking activity
Branch: molecular function
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0016477
Synonyms: Not Available
Branch: biological process
Genes: arx-7 (Cel)
Source: DOID:3908
Definition: A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
Genes: arx-7 (Cel)
(WBcel235)I:3069332G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069332G>A
Genes: arx-7 (Cel), pign-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069332G>A
Gene Cross References: arx-7
(WBcel235)I:3069687C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069687C>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069687C>T
Gene Cross References: arx-7
(WBcel235)I:3069586A>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069586A>G
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069586A>G
Gene Cross References: arx-7
(WBcel235)I:3069554A>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069554A>G
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069554A>G
Gene Cross References: arx-7
(WBcel235)I:3069445A>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069445A>G
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069445A>G
Gene Cross References: arx-7
(WBcel235)I:3069509C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069509C>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069509C>T
Gene Cross References: arx-7
(WBcel235)I:3070034C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3070034C>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3070034C>T
Gene Cross References: arx-7
(WBcel235)I:3069780C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069780C>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069780C>T
Gene Cross References: arx-7
(WBcel235)I:3070052T>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3070052T>A
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3070052T>A
Gene Cross References: arx-7
(WBcel235)I:3069882G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069882G>A
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069882G>A
Gene Cross References: arx-7
(WBcel235)I:3069392C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069392C>T
Genes: arx-7 (Cel), pign-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069392C>T
Gene Cross References: arx-7
(WBcel235)I:3069638A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069638A>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069638A>T
Gene Cross References: arx-7
(WBcel235)I:3069830A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003279.8:g.3069830A>T
Genes: arx-7 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)I:3069830A>T
Gene Cross References: arx-7
Gene Ontology
Source: GO:0005856
Synonyms: Not Available
Branch: cellular component
Genes: arx-7 (Cel)
Gene Ontology
Source: GO:0005737
Synonyms: Not Available
Branch: cellular component
Genes: arx-7 (Cel)