Version: 8.1.0Date: Fri Apr 18 2025
Category
asp-3
(Caenorhabditis elegans)Gene
Name: ASpartyl Protease 3
Synonyms: H22K11.1, CELE_H22K11.1
Source: WB:WBGene00000216
Biotype: protein coding gene
Symbol: asp-3 (Cel)
Symbol: asp-3
Gene Synopsis: asp-3 encodes an aspartyl protease homolog that is required, in parallel with ASP-4 but downstream of
Cross References: WB:asp-3...asp-3...asp-3
REN
(Homo sapiens)Gene
Name: renin
Synonyms: RTD, HNFJ2, renin precursor, renal, FLJ10761, angiotensinogenase, angiotensin-forming enzyme, ADTKD4, renin 1
Source: HGNC:9958
Biotype: protein coding gene
Strict Orthology Symbols: asp-3
NAPSA
(Homo sapiens)Gene
Name: napsin A aspartic peptidase
Synonyms: NAPA, SNAPA, ASP4, Kdap, kidney-derived aspartic protease-like protein, napsin-A, NAP1, CTB-191K22.6, TA01/TA02, pronapsin A, KAP, napsin-1, aspartyl protease 4, asp 4
Source: HGNC:13395
Biotype: protein coding gene
Strict Orthology Symbols: asp-3
PEP4
(Saccharomyces cerevisiae)Gene
Name: carboxyPEPtidase Y-deficient
Synonyms: yscA, PHO9, PRA1, YPL154C
Source: SGD:S000006075
Biotype: protein coding gene
Strict Orthology Symbols: asp-3
Bace
(Drosophila melanogaster)Gene
Name: beta-site APP-cleaving enzyme
Synonyms: CG13095, dBACE, dBace, dBAce, DASP2, BACE-1, anon-WO0140519.142, beta-site APP-cleaving enzyme, BACE
Source: FB:FBgn0032049
Biotype: protein coding gene
Strict Orthology Symbols: asp-3
tm4559
(Caenorhabditis elegans)Allele/Variant
Source: WB:WBVar01474049
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: asp-3 (Cel)
asp-4
(Caenorhabditis elegans)Gene
Name: ASpartyl Protease 4
Synonyms: CELE_R12H7.2, R12H7.2
Source: WB:WBGene00000217
Biotype: protein coding gene
Gene Synopsis: asp-4 encodes an aspartyl protease homolog that is required, in parallel with ASP-3 but downstream of
Source: DOID:0080827
Definition: A viral infectious disease that has_material_basis_in Human betaherpesvirus 5.
Genes: asp-3 (Cel)
Gene Ontology
Source: GO:0097300
Synonyms:
- programmed cell death by necrosis
- regulated necrosis
Branch: biological process
Genes: asp-3 (Cel)
Disease
Source: DOID:10881
Definition: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Enterovirus A (Enterovirus alphacoxsackie), which are transmitted_by contaminated fomites, and transmitted_by contact with nose and throat secretions, saliva, blister fluid and stool of infected persons. The infection has_symptom fever, has_symptom poor appetite, has_symptom malaise, has_symptom sore throat, has_symptom painful sores in the mouth, and has_symptom skin rash on the palms of the hands and soles of the feet.
Genes: asp-3 (Cel)
clp-1
(Caenorhabditis elegans)Gene
Name: CaLPain family 1
Synonyms: CELE_C06G4.2, C06G4.2
Source: WB:WBGene00000542
Biotype: protein coding gene
Gene Synopsis: active site and a Ca[2+]-binding domain; CLP-1 is required, in parallel with TRA-3 but in series with ASP
Source: DOID:0060062
Definition: A kidney disease that is characterized by normal urinalysis and slowly progressive chronic kidney disease, usually first noted in the teen years and progressing to end-stage renal disease between the third and seventh decades.
Genes: asp-3 (Cel)
Source: DOID:0050811
Definition: A steroid inherited metabolic disorder that is characterized by adrenal insufficiency and variable degrees of hyper or hypo androgyny manifestations resulting from steroidogenic enzyme deficiency.
Genes: asp-3 (Cel)
Disease
Source: DOID:446
Definition: An adrenal gland hyperfunction disease that results in the overproduction of aldosterone by the adrenal glands.
Genes: asp-3 (Cel)
Disease
Source: DOID:8544
Definition: A syndrome that involves prolonged and severe tiredness or weariness that is unrelated to exertion, is not relieved by rest and for a minimum of six months and is not directly caused by other conditions.
Genes: asp-3 (Cel)
Gene Ontology
Source: GO:0012501
Synonyms:
- PCD
- RCD
Branch: biological process
Genes: asp-3 (Cel)
Gene Ontology
Source: GO:0004190
Synonyms:
- aspartate protease activity
- aspartic endopeptidase activity
Branch: molecular function
Genes: asp-3 (Cel)
Disease
Source: DOID:10825
Definition: A hypertension with no known cause. It is the most common type of hypertension.
Genes: asp-3 (Cel)
Disease
Source: DOID:14115
Definition: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities.
Genes: asp-3 (Cel)
Disease
Source: DOID:0060224
Definition: A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain.
Genes: asp-3 (Cel)
Disease
Source: DOID:1596
Definition: A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function.
Genes: asp-3 (Cel)
Gene Ontology
Source: GO:0005764
Synonyms: Not Available
Branch: cellular component
Genes: asp-3 (Cel)
Disease
Source: DOID:6000
Definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.
Genes: asp-3 (Cel)
Gene Ontology
Source: GO:0006915
Synonyms:
- activation of apoptosis
- apoptosis
Branch: biological process
Genes: asp-3 (Cel)
(WBcel235)X:6791258C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791258C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791258C>T
Gene Cross References: asp-3
(WBcel235)X:6792431T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792431T>C
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792431T>C
Gene Cross References: asp-3
(WBcel235)X:6792562C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792562C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792562C>T
Gene Cross References: asp-3
(WBcel235)X:6792353G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792353G>A
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792353G>A
Gene Cross References: asp-3
(WBcel235)X:6792426G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792426G>A
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792426G>A
Gene Cross References: asp-3
(WBcel235)X:6791320C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791320C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791320C>T
Gene Cross References: asp-3
(WBcel235)X:6792398A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792398A>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792398A>T
Gene Cross References: asp-3
(WBcel235)X:6792611C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792611C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792611C>T
Gene Cross References: asp-3
(WBcel235)X:6791836C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791836C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791836C>T
Gene Cross References: asp-3
(WBcel235)X:6791958C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791958C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791958C>T
Gene Cross References: asp-3
(WBcel235)X:6792572G>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792572G>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792572G>T
Gene Cross References: asp-3
(WBcel235)X:6791281A>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791281A>G
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791281A>G
Gene Cross References: asp-3
(WBcel235)X:6792665T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792665T>C
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792665T>C
Gene Cross References: asp-3
(WBcel235)X:6792455C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792455C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792455C>T
Gene Cross References: asp-3
(WBcel235)X:6792691A>G
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792691A>G
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792691A>G
Gene Cross References: asp-3
(WBcel235)X:6791221C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791221C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791221C>T
Gene Cross References: asp-3
(WBcel235)X:6792258T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792258T>C
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792258T>C
Gene Cross References: asp-3
(WBcel235)X:6791313G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791313G>A
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791313G>A
Gene Cross References: asp-3
(WBcel235)X:6791378A>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791378A>C
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791378A>C
Gene Cross References: asp-3
(WBcel235)X:6792313C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792313C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792313C>T
Gene Cross References: asp-3
(WBcel235)X:6791190C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791190C>T
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791190C>T
Gene Cross References: asp-3
(WBcel235)X:6791695G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791695G>A
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791695G>A
Gene Cross References: asp-3
(WBcel235)X:6791798T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6791798T>C
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6791798T>C
Gene Cross References: asp-3
(WBcel235)X:6792413G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.6792413G>A
Genes: asp-3 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:6792413G>A
Gene Cross References: asp-3