Version: 8.0.0
Date: Tue Jan 28 2025
545 results for brk1

Brk1

(Rattus norvegicus)
Gene
Name: BRICK1 subunit of SCAR/WAVE actin nucleating complex
Synonyms: similar to chromosome 3 open reading frame 10, LOC679934, BRICK1, SCAR/WAVE actin-nucleating complex subunit, probable protein BRICK1, hypothetical protein LOC679934
Source: RGD:1598136
Biotype: protein coding gene
Symbol: Brk1 (Rno)
Symbol: Brk1
Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex); PARTICIPATES IN platelet-derived
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1

brk1

(Danio rerio)
Gene
Name: BRICK1 subunit of SCAR/WAVE actin nucleating complex
Synonyms: zgc:86903
Source: ZFIN:ZDB-GENE-040625-77
Biotype: protein coding gene
Symbol: brk1 (Dre)
Symbol: brk1
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1

Brk1

(Mus musculus)
Gene
Name: BRICK1, SCAR/WAVE actin-nucleating complex subunit
Synonyms: 6720456B07Rik, AW011779, expressed sequence AW011779, RIKEN cDNA 6720456B07 gene
Source: MGI:1915406
Biotype: protein coding gene
Symbol: Brk1 (Mmu)
Symbol: Brk1
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1
Alleles: Brk1 (Mmu)

BRK1

(Homo sapiens)
Gene
Name: BRICK1 subunit of SCAR/WAVE actin nucleating complex
Synonyms: MDS027, Brk1-like, haematopoietic stem/progenitor cell protein 300, BRICK1, SCAR/WAVE actin-nucleating complex subunit, homolog, C3orf10, hHBrk1, BRICK1, SCAR/WAVE actin nucleating complex subunit, HSPC300, BRICK1, SCAR/WAVE actin-nucleating complex subunit, probable protein BRICK1, protein BRICK1
Source: HGNC:23057
Biotype: protein coding gene
Symbol: BRK1 (Hsa)
Symbol: BRK1
Strict Orthology Symbols: brk1

brk1

(Xenopus tropicalis)
Gene
Name: BRICK1, SCAR/WAVE actin-nucleating complex subunit
Synonyms: brick1, brk1-a, brk1, brk1-b, BRICK1, SCAR/WAVE actin-nucleating complex subunit
Source: Xenbase:XB-GENE-1009798
Biotype: gene
Symbol: brk1
Symbol: brk1 (Xtr)
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Synonyms: brk1...brk1...brk1
Strict Orthology Symbols: brk1

brk1.S

(Xenopus laevis)
Gene
Name: BRICK1, SCAR/WAVE actin-nucleating complex subunit
Synonyms: brick1, brk1-a, brk1-b, brk1.S, BRICK1, SCAR/WAVE actin-nucleating complex subunit
Source: Xenbase:XB-GENE-1009803
Biotype: gene
Symbol: brk1.S (Xla)
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1
Symbol: brk1.S

brk1.L

(Xenopus laevis)
Gene
Name: BRICK1, SCAR/WAVE actin-nucleating complex subunit
Synonyms: brick1, brk1.L, brk1-a, brk1-b, BRICK1, SCAR/WAVE actin-nucleating complex subunit
Source: Xenbase:XB-GENE-6254645
Biotype: gene
Symbol: brk1.L (Xla)
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1
Symbol: brk1.L

Brk1Gt(DC0002)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:3872157
Genes: Brk1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Brk1 (Mmu)
Genes: Brk1 (Mmu)
Symbol: Brk1Gt(DC0002)Wtsi

BRK1P2

(Homo sapiens)
Gene
Name: BRK1 pseudogene 2
Synonyms: BRICK1, SCAR/WAVE actin-nucleating complex subunit pseudogene 2
Source: HGNC:42021
Biotype: pseudogene
Symbol: BRK1P2 (Hsa)
Symbol: BRK1P2

BRK1P1

(Homo sapiens)
Gene
Name: BRICK1 pseudogene 1
Synonyms: Not Available
Source: HGNC:42020
Biotype: pseudogene
Symbol: BRK1P1 (Hsa)
Symbol: BRK1P1

Brk1Gt(DC0002)Wtsi/Brk1Gt(DC0002)Wtsi [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:4840234
Synonyms: Not Available
Symbol: Brk1/Brk1 [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Brk1 (Mmu)
Alleles: Brk1 (Mmu)
Name: Brk1/Brk1 [background:] involves: 129P2/OlaHsd

Y57G11C.1147

(Caenorhabditis elegans)
Gene
Name: Protein BRICK1
Synonyms: CELE_Y57G11C.1147
Source: WB:WBGene00303007
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Strict Orthology Symbols: brk1

HSPC300

(Drosophila melanogaster)
Gene
Name: Haematopoietic stem/progenitor cell protein 300
Synonyms: dHSPC, SIP1, CG30173, hspc300, Brk1, Syntaxin Interacting Protein 1, HSPC300, dHSPC300
Source: FB:FBgn0061198
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Synonyms: Brk1...Brk1
Strict Orthology Symbols: brk1

regulation of actin polymerization or depolymerization

Gene Ontology
Source: GO:0008064
Synonyms: Not Available
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...brk1 (Dre)...Brk1 (Mmu)

AB + CRISPR1-brk1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210615-9
Synonyms: Not Available
Genes: brk1 (Dre)
Name: AB + CRISPR1-brk1

la027276Tg

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-130129-2188
Genes: brk1 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: brk1 (Dre)

twu34Tg + CRISPR1-brk1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210615-5
Synonyms: Tg(cmlc2:GFP)
Genes: brk1 (Dre)
Name: twu34Tg + CRISPR1-brk1

SCAR complex

Gene Ontology
Source: GO:0031209
Synonyms:
  • WAVE complex
  • WAVE regulatory complex
Branch: cellular component
Genes: Brk1 (Rno)...BRK1 (Hsa)...brk1 (Dre)...Brk1 (Mmu)

positive regulation of Arp2/3 complex-mediated actin nucleation

Gene Ontology
Source: GO:2000601
Synonyms:
  • positive regulation of actin filament branch nucleation
  • positive regulation of branched actin filament nucleation
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

Ecol\lacZdpp.APr(brk1)D

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0362096
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Ecol\lacZbrk1)D>
Constructs: P{dpp-lacZ.APr(brk1)D}...APr(brk1)D

positive regulation of lamellipodium assembly

Gene Ontology
Source: GO:0010592
Synonyms:
  • positive regulation of lamellipodium biogenesis
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

cell motility

Gene Ontology
Source: GO:0048870
Synonyms:
  • cell locomotion
  • cell movement
Branch: biological process
Genes: brk1 (Dre)...Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

Rac protein signal transduction

Gene Ontology
Source: GO:0016601
Synonyms:
  • Rac mediated signal transduction
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

positive regulation of protein-containing complex assembly

Gene Ontology
Source: GO:0031334
Synonyms:
  • activation of protein complex assembly
  • positive regulation of protein complex assembly
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

HSPC30086.1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0220486
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: Brk1

HSPC300SH1905

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0227062
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: Brk1

Hsap\BRK1UAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0366445
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\BRK1
Construct Expressed Component: BRK1 (Hsa)

HSPC300CR00795-TG4.1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0342591
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: Brk1

HSPC300e00059

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0227060
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: Brk1

fibroblast proliferation

Gene Ontology
Source: GO:0048144
Synonyms: Not Available
Branch: biological process
Genes: Brk1 (Rno)...BRK1 (Hsa)...Brk1 (Mmu)

positive regulation of fibroblast proliferation

Gene Ontology
Source: GO:0048146
Synonyms:
  • activation of fibroblast proliferation
  • stimulation of fibroblast proliferation
Branch: biological process
Genes: Brk1 (Mmu)...Brk1 (Rno)...BRK1 (Hsa)

actin filament organization

Gene Ontology
Source: GO:0007015
Synonyms:
  • actin filament organisation
  • regulation of actin filament localization
Branch: biological process
Genes: brk1 (Dre)...Brk1 (Mmu)...Brk1 (Rno)...BRK1 (Hsa)

lamellipodium

Gene Ontology
Source: GO:0030027
Synonyms: Not Available
Branch: cellular component
Genes: Brk1 (Mmu)...Brk1 (Rno)...BRK1 (Hsa)

actin cytoskeleton organization

Gene Ontology
Source: GO:0030036
Synonyms:
  • actin cytoskeleton organisation
  • actin cytoskeleton organization and biogenesis
Branch: biological process
Genes: BRK1 (Hsa)...Brk1 (Mmu)...Brk1 (Rno)

in utero embryonic development

Gene Ontology
Source: GO:0001701
Synonyms: Not Available
Branch: biological process
Genes: BRK1 (Hsa)...Brk1 (Mmu)...Brk1 (Rno)

small GTPase binding

Gene Ontology
Source: GO:0031267
Synonyms:
  • ADP-ribosylation factor binding
  • ARF binding
Branch: molecular function
Genes: BRK1 (Hsa)...Brk1 (Mmu)...Brk1 (Rno)

protein-containing complex binding

Gene Ontology
Source: GO:0044877
Synonyms:
  • macromolecular complex binding
  • protein complex binding
Branch: molecular function
Genes: Brk1 (Rno)...brk1 (Dre)...BRK1 (Hsa)...Brk1 (Mmu)

extracellular exosome

Gene Ontology
Source: GO:0070062
Synonyms:
  • exosome
  • extracellular vesicular exosome
Branch: cellular component
Genes: BRK1 (Hsa)

(R6)2R:24028548A>T

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028548A>T
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028548A>T
Gene Synonyms: Brk1

(R6)2R:24028549T>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028549T>G
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028549T>G
Gene Synonyms: Brk1

(R6)2R:24028669A>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028669A>G
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)2R:24028669A>G
Gene Synonyms: Brk1

(R6)2R:24027930T>C

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24027930T>C
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)2R:24027930T>C
Gene Synonyms: Brk1

(R6)2R:24028132G>A

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028132G>A
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028132G>A
Gene Synonyms: Brk1

(R6)2R:24028291A>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028291A>G
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028291A>G
Gene Synonyms: Brk1

cytoskeleton

Gene Ontology
Source: GO:0005856
Synonyms: Not Available
Branch: cellular component
Genes: Brk1 (Rno)...BRK1 (Hsa)...brk1 (Dre)...Brk1 (Mmu)

(R6)2R:24028280G>T

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028280G>T
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028280G>T
Gene Synonyms: Brk1

(R6)2R:24028008G>C

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028008G>C
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)2R:24028008G>C
Gene Synonyms: Brk1

(R6)2R:24028395G>A

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028395G>A
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028395G>A
Gene Synonyms: Brk1

(R6)2R:24028402C>T

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028402C>T
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028402C>T
Gene Synonyms: Brk1

(R6)2R:24028403A>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.24028403A>G
Genes: HSPC300 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:24028403A>G
Gene Synonyms: Brk1