Version: 8.1.0
Date: Fri Apr 18 2025
96 results for dio3

DIO3

(Homo sapiens)
Gene
Name: iodothyronine deiodinase 3
Synonyms: deiodinase, iodothyronine type III, TXDI3, thyroxine deiodinase type III (selenoprotein), type III iodothyronine deiodinase, type 3 DI, type-III 5'-deiodinase, DIOIII, thyroxine 5-deiodinase, iodothyronine deiodinase, placental type, D3, 5DIII, deiodinase, iodothyronine, type III, selenoprotein DIO3, type 3 iodothyronine selenodeiodinase, type-III 5' deiodinase
Source: HGNC:2885
Biotype: protein coding gene
Symbol: DIO3 (Hsa)
Symbol: DIO3
Synonyms: selenoprotein DIO3
Strict Orthology Symbols: dio3

Dio3

(Mus musculus)
Gene
Name: deiodinase, iodothyronine type III
Synonyms: 5DIII, DIOIII
Source: MGI:1306782
Biotype: protein coding gene
Symbol: Dio3 (Mmu)
Symbol: Dio3
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Strict Orthology Symbols: dio3
Alleles: Dio3 (Mmu)...Dio3 (Mmu)...Dio3 (Mmu)...Dio3 (Mmu)...Dio3 (Mmu)

Dio3

(Rattus norvegicus)
Gene
Name: iodothyronine deiodinase 3
Synonyms: 5DIII, type III iodothyronine deiodinase, deiodinase, iodothyronine, type 3, deiodinase iodothyronine type III, type 3 DI, deiodinase, iodothyronine, type III, type-III 5'-deiodinase, deiodinase iodothyronine type 3, DIOIII, thyroxine 5-deiodinase
Source: RGD:68420
Biotype: protein coding gene
Symbol: Dio3 (Rno)
Symbol: Dio3
Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3); INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Strict Orthology Symbols: dio3

dio3

(Xenopus tropicalis)
Gene
Name: deiodinase, iodothyronine, type 3
Synonyms: 5DIII, iodothyronine 5-deiodinase type III, deiodinase, iodothyronine, type 3, dio3, type 3 deiodinase, DI-3, D3
Source: Xenbase:XB-GENE-487490
Biotype: gene
Symbol: dio3 (Xtr)
Symbol: dio3
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Synonyms: dio3...dio3...dio3
Strict Orthology Symbols: dio3.S...dio3.L...DIO3...Dio3...dio3a

dio3b

(Danio rerio)
Gene
Name: iodothyronine deiodinase 3b
Synonyms: dio3, si:ch211-156m19.1, D3
Source: ZFIN:ZDB-GENE-070705-53
Biotype: protein coding gene
Symbol: dio3b (Dre)
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Synonyms: dio3...dio3...dio3
Strict Orthology Symbols: dio3
Symbol: dio3b

dio3a

(Danio rerio)
Gene
Name: iodothyronine deiodinase 3a
Synonyms: Not Available
Source: ZFIN:ZDB-GENE-120406-7
Biotype: protein coding gene
Symbol: dio3a (Dre)
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Strict Orthology Symbols: dio3
Symbol: dio3a

DIO3OS

(Homo sapiens)
Gene
Name: DIO3 opposite strand upstream RNA
Synonyms: DIO3-AS1, DIO3-OS, C14orf134, NCRNA00041, DIO3 opposite strand/antisense RNA (head to head)
Source: HGNC:20348
Biotype: ncRNA gene
Symbol: DIO3OS (Hsa)
Gene Synopsis: The mouse and human DIO3OS and DIO3 (MIM 601038) genes overlap and are transcribed in opposite directions...The mouse Dio3 gene is imprinted from the paternal allele during fetal development, suggesting that DIO3OS...is a noncoding gene that may have a role in maintaining monoallelic expression of DIO3 (Hernandez et
Synonyms: DIO3 opposite strand/antisense RNA (head to head)
Strict Orthology Symbols: Dio3os
Symbol: DIO3OS

dio3.L

(Xenopus laevis)
Gene
Name: deiodinase, iodothyronine, type 3
Synonyms: 5DIII, iodothyronine 5-deiodinase type III, deiodinase, iodothyronine, type 3, type 3 deiodinase, dio3.L, DI-3, D3
Source: Xenbase:XB-GENE-865707
Biotype: gene
Symbol: dio3.L (Xla)
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Strict Orthology Symbols: dio3
Symbol: dio3.L

dio3.S

(Xenopus laevis)
Gene
Name: deiodinase, iodothyronine, type 3
Synonyms: 5DIII, iodothyronine 5-deiodinase type III, dio3.S, deiodinase, iodothyronine, type 3, type 3 deiodinase, DI-3, D3
Source: Xenbase:XB-GENE-17336015
Biotype: gene
Symbol: dio3.S (Xla)
Automated Gene Synopsis: Orthologous to human DIO3 (iodothyronine deiodinase 3).
Strict Orthology Symbols: dio3
Symbol: dio3.S

Dio3os

(Rattus norvegicus)
Gene
Name: DIO3 opposite strand upstream RNA
Synonyms: LOC102546650, uncharacterized LOC102546650, DIO3 opposite strand/antisense RNA (head to head)
Source: RGD:7653627
Biotype: protein coding gene
Symbol: Dio3os (Rno)
Synonyms: DIO3 opposite strand/antisense RNA (head to head)
Strict Orthology Symbols: DIO3OS
Symbol: Dio3os

Dio3os

(Mus musculus)
Gene
Name: deiodinase, iodothyronine type III, opposite strand
Synonyms: AW556460, expressed sequence AW556460, Dio3as
Source: MGI:2664395
Biotype: bidirectional promoter lncRNA gene
Symbol: Dio3os (Mmu)
Strict Orthology Symbols: DIO3OS
Symbol: Dio3os

Dio3tm1Dmst

(Mus musculus)
Allele/Variant
Source: MGI:5707059
Genes: Dio3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Dio3 (Mmu)
Genes: Dio3 (Mmu)
Symbol: Dio3tm1Dmst

Dio3em2Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7462095
Genes: Dio3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Dio3 (Mmu)
Genes: Dio3 (Mmu)
Symbol: Dio3em2Gpt

Dio3em1(IMPC)Kmpc

(Mus musculus)
Allele/Variant
Source: MGI:7377580
Genes: Dio3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Dio3 (Mmu)
Genes: Dio3 (Mmu)
Symbol: Dio3em1(IMPC)Kmpc

Dio3tm2Stg

(Mus musculus)
Allele/Variant
Source: MGI:7736212
Genes: Dio3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Dio3 (Mmu)
Genes: Dio3 (Mmu)
Symbol: Dio3tm2Stg

Dio3tm1Stg

(Mus musculus)
Allele/Variant
Source: MGI:2664293
Genes: Dio3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Dio3 (Mmu)
Genes: Dio3 (Mmu)
Symbol: Dio3tm1Stg

Dio3tm1Stg/Dio3tm1Stg [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL/6

(Mus musculus)
Model
Id: MGI:3620674
Synonyms: Not Available
Symbol: Dio3/Dio3 [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL/6 (Mmu)
Genes: Dio3 (Mmu)
Alleles: Dio3 (Mmu)
Name: Dio3/Dio3 [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Dio3tm1Dmst/Dio3tm1Dmst Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ [background:] involves: C57BL/6 * DBA

(Mus musculus)
Model
Id: MGI:5770122
Synonyms: Not Available
Symbol: Dio3/Dio3 Speer6-ps1/Speer6-ps1<+> [background:] involves: C57BL
Genes: Dio3 (Mmu)
Alleles: Dio3 (Mmu)
Name: Dio3/Dio3 Speer6-ps1/Speer6-ps1<+> [background:] involves: C57BL

thyroxine 5-deiodinase activity

Gene Ontology
Source: GO:0033798
Synonyms:
  • acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity
  • diiodothyronine 5'-deiodinase activity
Branch: molecular function
Genes: Dio3 (Mmu)...DIO3 (Hsa)...dio3b (Dre)...Dio3 (Rno)

thyroxine 5'-deiodinase activity

Gene Ontology
Source: GO:0004800
Synonyms:
  • L-thyroxine iodohydrolase (reducing) activity
  • acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)
Branch: molecular function
Genes: Dio3 (Mmu)...Dio3 (Rno)...DIO3 (Hsa)...dio3a (Dre)...dio3b (Dre)

thyroid hormone catabolic process

Gene Ontology
Source: GO:0042404
Synonyms:
  • thyroid hormone breakdown
  • thyroid hormone catabolism
Branch: biological process
Genes: Dio3 (Mmu)...DIO3 (Hsa)...Dio3 (Rno)

retinal cone cell apoptotic process

Gene Ontology
Source: GO:0097474
Synonyms:
  • cone photoreceptor apoptotic process
Branch: biological process
Genes: Dio3 (Mmu)...DIO3 (Hsa)...Dio3 (Rno)

brown fat cell proliferation

Gene Ontology
Source: GO:0070342
Synonyms:
  • brown adipocyte proliferation
  • brown adipose cell proliferation
Branch: biological process
Genes: Dio3 (Mmu)...DIO3 (Hsa)...Dio3 (Rno)

thyroid hormone metabolic process

Gene Ontology
Source: GO:0042403
Synonyms:
  • thyroid hormone metabolism
Branch: biological process
Genes: dio3a (Dre)...Dio3 (Rno)...Dio3 (Mmu)...DIO3 (Hsa)...dio3b (Dre)

hormone biosynthetic process

Gene Ontology
Source: GO:0042446
Synonyms:
  • hormone anabolism
  • hormone biosynthesis
Branch: biological process
Genes: Dio3 (Rno)...dio3a (Dre)...Dio3 (Mmu)...DIO3 (Hsa)...dio3b (Dre)

mpv17a9; zf15Tg + MO1-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-5924
Synonyms: Not Available
Genes: dio3b (Dre)

mpv17a9/a9; ba2Tg + MO1-dio3b + MO4-tp53

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-191001-3
Synonyms: Not Available
Genes: dio3b (Dre)

AB + MO2-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-19669
Synonyms: Not Available
Genes: dio3b (Dre)

AB + MO4-dio3a

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-7894
Synonyms: Not Available
Genes: dio3a (Dre)

mpv17a9/a9; ba2Tg + MO1-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-9488
Synonyms: Not Available
Genes: dio3b (Dre)

mpv17a9/a9; zf13Tg + MO1-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-20395
Synonyms: Not Available
Genes: dio3b (Dre)

AB + MO3-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-3349
Synonyms: Not Available
Genes: dio3b (Dre)

AB + MO3-dio3a

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-28762
Synonyms: Not Available
Genes: dio3a (Dre)

WIK + MO1-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-6334
Synonyms: WIK11
Genes: dio3b (Dre)

retinal cone cell development

Gene Ontology
Source: GO:0046549
Synonyms: Not Available
Branch: biological process
Genes: Dio3 (Rno)...Dio3 (Mmu)...DIO3 (Hsa)

WIK + MO1-dio3a

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-26317
Synonyms: WIK11
Genes: dio3a (Dre)

WT + MO1-dio3b

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-19218
Synonyms: Not Available
Genes: dio3b (Dre)

regulation of neural retina development

Gene Ontology
Source: GO:0061074
Synonyms: Not Available
Branch: biological process
Genes: dio3b (Dre)

swim bladder development

Gene Ontology
Source: GO:0048794
Synonyms:
  • gas bladder development
Branch: biological process
Genes: dio3b (Dre)

fetal alcohol spectrum disorder

Disease
Source: DOID:0050696
Definition: A specific developmental disorder and physical disorder that is characterized by physical, behavioral and learning birth defects resulting from maternal ingestion of alcohol during pregnancy.
Genes: Dio3 (Rno)...dio3 (Xtr)...DIO3 (Hsa)...dio3a (Dre)...Dio3 (Mmu)

positive regulation of multicellular organism growth

Gene Ontology
Source: GO:0040018
Synonyms:
  • positive regulation of body growth
  • positive regulation of body size
Branch: biological process
Genes: Dio3 (Rno)...DIO3 (Hsa)...Dio3 (Mmu)

swimming behavior

Gene Ontology
Source: GO:0036269
Synonyms:
  • swimming behaviour
Branch: biological process
Genes: dio3b (Dre)

chordate embryonic development

Gene Ontology
Source: GO:0043009
Synonyms: Not Available
Branch: biological process
Genes: dio3a (Dre)...dio3b (Dre)

pharyngeal system development

Gene Ontology
Source: GO:0060037
Synonyms: Not Available
Branch: biological process
Genes: dio3b (Dre)

congestive heart failure

Disease
Source: DOID:6000
Definition: A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body.
Genes: Dio3 (Rno)...dio3 (Xtr)...dio3a (Dre)...DIO3 (Hsa)...Dio3 (Mmu)

endosome membrane

Gene Ontology
Source: GO:0010008
Synonyms:
  • endosomal membrane
Branch: cellular component
Genes: DIO3 (Hsa)...Dio3 (Rno)...Dio3 (Mmu)

response to hypoxia

Gene Ontology
Source: GO:0001666
Synonyms:
  • response to hypoxic stress
  • response to intermittent hypoxia
Branch: biological process
Genes: DIO3 (Hsa)...Dio3 (Rno)...Dio3 (Mmu)

(GRCh38)14:101552507G>A

(Homo sapiens)
Allele/Variant
Source: rs267603879
Genes: DIO3OS (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:101552507G>A
Gene Synonyms: DIO3 opposite strand/antisense RNA (head to head)

(GRCh38)14:101592473T>C

(Homo sapiens)
Allele/Variant
Source: rs207475202
Genes: DIO3OS (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:101592473T>C
Gene Synonyms: DIO3 opposite strand/antisense RNA (head to head)

liver development

Gene Ontology
Source: GO:0001889
Synonyms: Not Available
Branch: biological process
Genes: dio3b (Dre)