[object Object]

Category

233 results for dph2

Page 1 of 5

DPH2

(Saccharomyces cerevisiae)

Gene

Name: DiPHthamide

Synonyms: YKL191W

Source: SGD:S000001674

Biotype: protein coding gene

Symbol: DPH2 (Sce)

Symbol: DPH2

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

Alleles: dph2-Δ (Sce)

Dph2

(Drosophila melanogaster)

Gene

Name: Diphthamide biosynthesis 2

Synonyms: CG7265

Source: FB:FBgn0038272

Biotype: protein coding gene

Symbol: Dph2 (Dme)

Symbol: Dph2

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

Alleles: Dph2 (Dme)

DPH2

(Homo sapiens)

Gene

Name: diphthamide biosynthesis 2

Synonyms: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, diphthamide biosynthesis-like protein 2, DEDSSH2, DPH2 homolog, DPH2-like 2, diphtheria toxin resistance protein 2, diphthamide biosynthesis protein 2, hsDph2, DPH2L2, dph2-like 2 (s. cerevisiae), diphthamide biosynthesis protein 2 homolog-like 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2, diptheria toxin resistance protein required for diphthamide biosynthesis-like 2

Source: HGNC:3004

Biotype: protein coding gene

Symbol: DPH2 (Hsa)

Symbol: DPH2

Synonyms: DPH2 homolog

Strict Orthology Symbols: dph2

dph2

(Danio rerio)

Gene

Name: diphthamide biosynthesis 2

Synonyms: zgc:162269, id:ibd5058

Source: ZFIN:ZDB-GENE-030219-100

Biotype: protein coding gene

Symbol: dph2 (Dre)

Symbol: dph2

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

Disease (2)

Dph2

(Rattus norvegicus)

Gene

Name: diphthamide biosynthesis 2

Synonyms: 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, MGC109459, diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2, DPH2 homolog (S. cerevisiae), S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2, DPH2 homolog, diphtheria toxin resistance protein 2, diphthamide biosynthesis protein 2, LOC298452, Dph2l2

Source: RGD:1304634

Biotype: protein coding gene

Symbol: Dph2 (Rno)

Symbol: Dph2

Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Synonyms: DPH2 homolog (S. cerevisiae)...DPH2 homolog

Strict Orthology Symbols: dph2

Dph2

(Mus musculus)

Gene

Name: DPH2 homolog

Synonyms: RIKEN cDNA 9130020C19 gene, diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 2, AI467389, expressed sequence AI467389, 9130020C19Rik, Dph2l2

Source: MGI:1914978

Biotype: protein coding gene

Symbol: Dph2 (Mmu)

Symbol: Dph2

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

Alleles: Dph2 (Mmu)...Dph2 (Mmu)...Dph2 (Mmu)

dph2

(Xenopus tropicalis)

Gene

Name: diphthamide biosynthesis 2

Synonyms: diphthamide biosynthesis 2, dph2

Source: Xenbase:XB-GENE-980245

Biotype: gene

Symbol: dph2

Symbol: dph2 (Xtr)

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Synonyms: dph2...dph2...dph2

Strict Orthology Symbols: dph2

Disease (2)

dph2.L

(Xenopus laevis)

Gene

Name: diphthamide biosynthesis 2

Synonyms: diphthamide biosynthesis 2, dph2.L

Source: Xenbase:XB-GENE-980248

Biotype: gene

Symbol: dph2.L (Xla)

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

Symbol: dph2.L

Disease (1)

dph2-Δ

(Saccharomyces cerevisiae)

Allele/Variant

Source: SGD:S000280712

Genes: DPH2 (Sce)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: dph2-Δ (Sce)

Genes: DPH2 (Sce)

Symbol: dph2-Δ

Gene (1)

Dph2^TKO.GS05152

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0349425

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Construct Knockdown Component: Dph2 (Dme)

Symbol: Dph2^TKO.GS05152

Dph2^GD12188

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0205398

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Construct Knockdown Component: Dph2 (Dme)

Symbol: Dph2^GD12188

Dph2^{tm1(KOMP)Vlcg}

(Mus musculus)

Allele/Variant

Source: MGI:3812959

Genes: Dph2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Mmu)

Genes: Dph2 (Mmu)

Symbol: Dph2^{tm1(KOMP)Vlcg}

Gene (1)

Dph2^KK100457

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0230765

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Construct Knockdown Component: Dph2 (Dme)

Symbol: Dph2^KK100457

Dph2^{UAS.ORF.GW.Tag:HA}

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0351031

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Symbol: Dph2^{UAS.ORF.GW.Tag:HA}

Construct Expressed Component: Dph2 (Dme)

Dph2^HMS02783

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0293423

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Construct Knockdown Component: Dph2 (Dme)

Symbol: Dph2^HMS02783

Dph2^{tm2(EUCOMM)Wtsi}

(Mus musculus)

Allele/Variant

Source: MGI:4840638

Genes: Dph2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Mmu)

Genes: Dph2 (Mmu)

Symbol: Dph2^{tm2(EUCOMM)Wtsi}

Dph2^em1Smoc

(Mus musculus)

Allele/Variant

Source: MGI:7626397

Genes: Dph2 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Mmu)

Genes: Dph2 (Mmu)

Symbol: Dph2^em1Smoc

Gene (1)

Dph2^{tm2(EUCOMM)Wtsi}/Dph2^{tm2(EUCOMM)Wtsi} [background:] C57BL/6N-A^tm1Brd Dph2^{tm2(EUCOMM)Wtsi}/WtsiH

(Mus musculus)

Model

Id: MGI:5631073

Synonyms: Not Available

Symbol: Dph2/Dph2 [background:] C57BL/6N-A Dph2/WtsiH

Genes: Dph2 (Mmu)

Alleles: Dph2 (Mmu)

Name: Dph2/Dph2 [background:] C57BL/6N-A Dph2/WtsiH

Gene (1)

Dph2^EP3533

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0131404

Genes: Dph2 (Dme)

Synonyms: Not Available

Variant Type: insertion

Molecular Consequence: 5_prime_UTR_variant

Diseases: Not Available

Variant Name: Not Available

Symbol: Dph2 (Dme)

Genes: Dph2 (Dme)

Symbol: Dph2^EP3533

dph-2

(Caenorhabditis elegans)

Gene

Name: DiPHthamide biosynthesis protein 2

Synonyms: C09G5.2, CELE_C09G5.2

Source: WB:WBGene00007488

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human DPH2 (diphthamide biosynthesis 2).

Strict Orthology Symbols: dph2

diphthamide deficiency syndrome

Disease

Source: DOID:0070476

Definition: An inherited metabolic disorder characterized by global developmental delay, short stature, dysmorphic craniofacial features, and sparse hair that has_material_basis_in deficient diphthamidylation of the eukaryotic translation Elongation Factor 2 protein (gene: EEF2).

Genes: Dph2 (Mmu)...Dph2 (Rno)...dph2 (Dre)...DPH2 (Hsa)...DPH2 (Sce)

diphthamide deficiency syndrome 2

Disease

Source: DOID:0070478

Definition: A diphthamide deficiency syndrome that has_material_basis_in homozygous or compound heterozygous mutations in the DPH2 gene on chromosome 1p34.1.

Genes: dph2 (Dre)...DPH2 (Hsa)...DPH2 (Sce)...Dph2 (Mmu)...Dph2 (Dme)

Gene (9)

2-(3-amino-3-carboxypropyl)histidine synthase complex

Gene Ontology

Source: GO:0120513

Synonyms:

Dph1-Dph2 complex

Branch: cellular component

Genes: Dph2 (Mmu)...Dph2 (Rno)...dph2 (Dre)...DPH2 (Hsa)...Dph2 (Dme)

Definition: The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes....The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.

Genes Annotated with this GO Term (13)

2-(3-amino-3-carboxypropyl)histidine synthase activity

Gene Ontology

Source: GO:0090560

Synonyms: Not Available

Branch: molecular function

Genes: Dph2 (Mmu)...Dph2 (Rno)...dph2 (Dre)...DPH2 (Hsa)...DPH2 (Sce)

Genes Annotated with this GO Term (14)

protein histidyl modification to diphthamide

Gene Ontology

Source: GO:0017183

Synonyms:

peptidyl-diphthamide anabolism from peptidyl-histidine
peptidyl-diphthamide biosynthetic process from peptidyl-histidine

Branch: biological process

Genes: Dph2 (Dme)...Dph2 (Rno)...Dph2 (Mmu)...dph2 (Dre)...DPH2 (Hsa)

Genes Annotated with this GO Term (49)

iron-sulfur cluster binding

Gene Ontology

Source: GO:0051536

Synonyms:

Fe/S binding
iron sulfur cluster binding

Branch: molecular function

Genes: DPH2 (Hsa)...DPH2 (Sce)...dph2 (Dre)

Genes Annotated with this GO Term (458)

4 iron, 4 sulfur cluster binding

Gene Ontology

Source: GO:0051539

Synonyms:

4 Fe 4 S cluster binding
4 iron, 4 sulphur cluster binding

Branch: molecular function

Genes: Dph2 (Rno)...DPH2 (Hsa)...Dph2 (Mmu)...dph2 (Dre)

Genes Annotated with this GO Term (253)

metal ion binding

Gene Ontology

Source: GO:0046872

Synonyms:

heavy metal binding
metal binding

Branch: molecular function

Genes: Dph2 (Mmu)...DPH2 (Sce)...Dph2 (Rno)...DPH2 (Hsa)...dph2 (Dre)

Genes Annotated with this GO Term (10000)

(GRCh38)1:43972245C>A

(Homo sapiens)

Allele/Variant

Source: NC_000001.11:g.43972245C>A

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43972245C>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971689C>T

(Homo sapiens)

Allele/Variant

Source: rs141223334

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971689C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971504G>A

(Homo sapiens)

Allele/Variant

Source: rs148897061

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971504G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971777G>A

(Homo sapiens)

Allele/Variant

Source: rs2085433092

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971777G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971079G>A

(Homo sapiens)

Allele/Variant

Source: rs775660985

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971079G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971608C>T

(Homo sapiens)

Allele/Variant

Source: rs761482007

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971608C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43972463G>T

(Homo sapiens)

Allele/Variant

Source: rs770120491

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43972463G>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971747G>T

(Homo sapiens)

Allele/Variant

Source: rs140036435

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971747G>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971413C>T

(Homo sapiens)

Allele/Variant

Source: rs767303260

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971413C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43972019C>T

(Homo sapiens)

Allele/Variant

Source: NC_000001.11:g.43972019C>T

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43972019C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970973G>C

(Homo sapiens)

Allele/Variant

Source: NC_000001.11:g.43970973G>C

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970973G>C

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970973G>A

(Homo sapiens)

Allele/Variant

Source: rs760762295

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970973G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971503C>T

(Homo sapiens)

Allele/Variant

Source: rs767455462

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971503C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970708G>T

(Homo sapiens)

Allele/Variant

Source: rs1571781453

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: splice_region_variant, missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, stop_gained

Diseases: Not Available

Variant Name: (GRCh38)1:43970708G>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970973G>T

(Homo sapiens)

Allele/Variant

Source: rs760762295

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970973G>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43971398A>C

(Homo sapiens)

Allele/Variant

Source: rs1571783805

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, intron_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43971398A>C

Gene Synonyms: DPH2 homolog

(GRCh38)1:43972469C>T

(Homo sapiens)

Allele/Variant

Source: rs147970330

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43972469C>T

Gene Synonyms: DPH2 homolog

(GRCh38)1:43972499G>A

(Homo sapiens)

Allele/Variant

Source: rs145817429

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43972499G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970239C>G

(Homo sapiens)

Allele/Variant

Source: rs1270961302

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970239C>G

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970672C>G

(Homo sapiens)

Allele/Variant

Source: NC_000001.11:g.43970672C>G

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, stop_gained, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970672C>G

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970704G>A

(Homo sapiens)

Allele/Variant

Source: rs765438963

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant, synonymous_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970704G>A

Gene Synonyms: DPH2 homolog

(GRCh38)1:43970687T>C

(Homo sapiens)

Allele/Variant

Source: rs950242509

Genes: DPH2 (Hsa)

Synonyms: Not Available

Variant Type: SNP

Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant

Diseases: Not Available

Variant Name: (GRCh38)1:43970687T>C

Gene Synonyms: DPH2 homolog

Page 1 of 5