Version: 8.1.0
Date: Fri Apr 18 2025
832 results for echs1

echs1

(Danio rerio)
Gene
Name: enoyl CoA hydratase, short chain, 1, mitochondrial
Synonyms: fj55e05, si:zc217g15.1, wu:fj55e05
Source: ZFIN:ZDB-GENE-030616-617
Biotype: protein coding gene
Symbol: echs1 (Dre)
Symbol: echs1
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: Echs1...ECHS1

Echs1

(Mus musculus)
Gene
Name: enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Synonyms: C80529, mECH1, expressed sequence C80529, mECH
Source: MGI:2136460
Biotype: protein coding gene
Symbol: Echs1 (Mmu)
Symbol: Echs1
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: echs1
Alleles: Echs1 (Mmu)...Echs1 (Mmu)...Echs1 (Mmu)...Echs1 (Mmu)...Echs1 (Mmu)

Echs1

(Drosophila melanogaster)
Gene
Name: Enoyl-CoA hydratase, short chain 1
Synonyms: Echs1, CG6543, CG18645
Source: FB:FBgn0033879
Biotype: protein coding gene
Symbol: Echs1 (Dme)
Symbol: Echs1
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Synonyms: Echs1...Echs1
Strict Orthology Symbols: echs1
Alleles: Echs1 (Dme)...Echs1 (Dme)...Echs1 (Dme)...Echs1 (Dme)

Echs1

(Rattus norvegicus)
Gene
Name: enoyl-CoA hydratase, short chain 1
Synonyms: short chain enoyl-CoA hydratase, enoyl-CoA hydratase 1, enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, enoyl CoA hydratase, short chain, 1, mitochondrial, enoyl-CoA hydratase, mitochondrial, Enoyl-CoA hydratase short chain 1 mitochondrial, mECH, enoyl Coenzyme A hydratase, short chain 1, LOC100911186, mECH1, SCEH, mitochondrial short-chain enoyl-coenzyme A hydratase 1, short-chain enoyl-CoA hydratase, Enoyl-CoA hydratase, short chain 1, mitochondrial, enoyl-CoA hydratase, mitochondrial-like
Source: RGD:69330
Biotype: protein coding gene
Symbol: Echs1 (Rno)
Symbol: Echs1
Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1); PARTICIPATES IN fatty acid beta degradation
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: echs1

ECHS1

(Homo sapiens)
Gene
Name: enoyl-CoA hydratase, short chain 1
Synonyms: short chain enoyl-CoA hydratase, enoyl-CoA hydratase 1, mECH1, SCEH, enoyl-CoA hydratase, short chain, 1, mitochondrial, enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, enoyl CoA hydratase, short chain, 1, mitochondrial, short-chain enoyl-CoA hydratase, ECHS1D, enoyl-CoA hydratase, mitochondrial, mECH
Source: HGNC:3151
Biotype: protein coding gene
Symbol: ECHS1 (Hsa)
Symbol: ECHS1
Strict Orthology Symbols: echs1

echs1

(Xenopus tropicalis)
Gene
Name: enoyl-CoA hydratase, short chain, 1, mitochondrial
Synonyms: echs1, enoyl-CoA hydratase, short chain, 1, mitochondrial
Source: Xenbase:XB-GENE-5945792
Biotype: gene
Symbol: echs1 (Xtr)
Symbol: echs1
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Synonyms: echs1...echs1...echs1
Strict Orthology Symbols: Echs1...ECHS1...echs1.L

echs1.L

(Xenopus laevis)
Gene
Name: enoyl-CoA hydratase, short chain, 1, mitochondrial
Synonyms: echs1.L, enoyl-CoA hydratase, short chain, 1, mitochondrial
Source: Xenbase:XB-GENE-5945929
Biotype: gene
Symbol: echs1.L (Xla)
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: echs1
Symbol: echs1.L

Echs1GD11954

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0205120
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1GD11954

Echs1em1Cya

(Mus musculus)
Allele/Variant
Source: MGI:7793156
Genes: Echs1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Mmu)
Genes: Echs1 (Mmu)
Symbol: Echs1em1Cya

Echs1GL01031

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0266353
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1GL01031

Echs1SH1959

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0225563
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Gene Synonyms: Echs1
Genes: Echs1 (Dme)
Symbol: Echs1SH1959

Echs1TKO.GS04304

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0349441
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1TKO.GS04304

Echs1HMC05228

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0315039
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1HMC05228

Echs1em1Jynz

(Mus musculus)
Allele/Variant
Source: MGI:6458749
Genes: Echs1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Mmu)
Genes: Echs1 (Mmu)
Symbol: Echs1em1Jynz

Echs1Gt(OST282061)Lex

(Mus musculus)
Allele/Variant
Source: MGI:3529802
Genes: Echs1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Mmu)
Genes: Echs1 (Mmu)
Symbol: Echs1Gt(OST282061)Lex

Echs1GLC01380

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0291853
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1GLC01380

Echs1CR00484-TG4.1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0340954
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: amino acid metabolic disorder
Variant Name: Not Available
Symbol: Echs1 (Dme)
Gene Synonyms: Echs1
Genes: Echs1 (Dme)
Symbol: Echs1CR00484-TG4.1

Echs1em2Cya

(Mus musculus)
Allele/Variant
Source: MGI:7793157
Genes: Echs1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Mmu)
Genes: Echs1 (Mmu)
Symbol: Echs1em2Cya

Echs1em1(IMPC)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:6361232
Genes: Echs1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Mmu)
Genes: Echs1 (Mmu)
Symbol: Echs1em1(IMPC)Hmgu

Echs1U6.NIG.sgRNA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0380782
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Construct Knockdown Component: Echs1 (Dme)
Symbol: Echs1U6.NIG.sgRNA

Echs1em1(IMPC)Hmgu/Echs1+ [background:] C57BL/6NCrl-Echs1em1(IMPC)Hmgu/Ieg

(Mus musculus)
Model
Id: MGI:7628970
Synonyms: Not Available
Symbol: Echs1/Echs1<+> [background:] C57BL/6NCrl-Echs1/Ieg (Mmu)
Genes: Echs1 (Mmu)
Alleles: Echs1 (Mmu)
Name: Echs1/Echs1<+> [background:] C57BL/6NCrl-Echs1/Ieg

Echs1em1Jynz/Echs1+ [background:] C57BL/6-Echs1em1Jynz

(Mus musculus)
Model
Id: MGI:6458755
Synonyms: Not Available
Symbol: Echs1/Echs1<+> [background:] C57BL/6-Echs1 (Mmu)
Genes: Echs1 (Mmu)
Alleles: Echs1 (Mmu)
Name: Echs1/Echs1<+> [background:] C57BL/6-Echs1

Echs1em1Jynz/Echs1em1Jynz [background:] C57BL/6-Echs1em1Jynz

(Mus musculus)
Model
Id: MGI:6458754
Synonyms: Not Available
Symbol: Echs1/Echs1 [background:] C57BL/6-Echs1 (Mmu)
Genes: Echs1 (Mmu)
Alleles: Echs1 (Mmu)
Name: Echs1/Echs1 [background:] C57BL/6-Echs1

Echs1NP1180

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0225562
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Gene Synonyms: Echs1
Genes: Echs1 (Dme)
Symbol: Echs1NP1180

Echs1EY08499

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0161144
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Echs1 (Dme)
Gene Synonyms: Echs1
Genes: Echs1 (Dme)
Symbol: Echs1EY08499

ech-6

(Caenorhabditis elegans)
Gene
Name: Enoyl-CoA Hydratase 6
Synonyms: T05G5.6, CELE_T05G5.6
Source: WB:WBGene00001155
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human ECHS1 (enoyl-CoA hydratase, short chain 1).
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: echs1

ech-7

(Caenorhabditis elegans)
Gene
Name: Enoyl-CoA Hydratase 7
Synonyms: Y105E8A.4, CELE_Y105E8A.4, Y105E8E.b
Source: WB:WBGene00001156
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human ECHS1 (enoyl-CoA hydratase, short chain 1).
Automated Gene Synopsis: Orthologous to human ECHS1 (enoyl-CoA hydratase, short chain 1).
Strict Orthology Symbols: echs1

mitochondrial short-chain enoyl-CoA hydratase 1 deficiency

Disease
Source: DOID:0070540
Definition: A mitochondrial metabolism disease characterized by a spectrum of phenotypes including delayed psychomotor development, neurodegeneration, increased lactic acid, brain lesions in the basal ganglia, and dystonia that has material basis in homozygous or compound heterozygous mutation in the ECHS1 gene on chromosome 10q26.3.
Genes: Echs1 (Rno)...Echs1 (Dme)...ECHS1 (Hsa)...echs1 (Dre)...Echs1 (Mmu)

3-hydroxypropionyl-CoA dehydratase activity

Gene Ontology
Source: GO:0043956
Synonyms:
  • 3-hydroxy propionyl-CoA dehydratase activity
  • AMP-dependent synthetase and ligase
Branch: molecular function
Genes: Echs1 (Rno)...Echs1 (Dme)...ECHS1 (Hsa)...Echs1 (Mmu)

crotonyl-CoA hydratase activity

Gene Ontology
Source: GO:0120092
Synonyms: Not Available
Branch: molecular function
Genes: Echs1 (Rno)...ECHS1 (Hsa)...Echs1 (Mmu)

enoyl-CoA hydratase activity

Gene Ontology
Source: GO:0004300
Synonyms:
  • (3S)-3-hydroxyacyl-CoA hydro-lyase activity
  • 2-enoyl-CoA hydratase activity
Branch: molecular function
Genes: Echs1 (Rno)...echs1 (Dre)...Echs1 (Dme)...ECHS1 (Hsa)...Echs1 (Mmu)

delta(3)-delta(2)-enoyl-CoA isomerase activity

Gene Ontology
Source: GO:0004165
Synonyms:
  • 3,2-trans-enoyl-CoA isomerase activity
  • acetylene-allene isomerase activity
Branch: molecular function
Genes: Echs1 (Rno)...echs1 (Dre)...ECHS1 (Hsa)...Echs1 (Mmu)

valine metabolic process

Gene Ontology
Source: GO:0006573
Synonyms:
  • valine metabolism
Branch: biological process
Genes: Echs1 (Dme)

Bulk RNA-seq analysis of the effects of ECHS1 knockdown on cardiomyocyte transcriptome

(Rattus norvegicus)
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by RGD
ID: GEO:GSE159039
Tags: unclassified
Summary: Short-Chain Enoyl-CoA Hydratase Mediates Histone Crotonylation and Contributes to Cardiac Homeostasis
Symbol: Bulk RNA-seq analysis of the effects of ECHS1 knockdown on cardiomyocyte transcriptome
Name: Bulk RNA-seq analysis of the effects of ECHS1 knockdown on cardiomyocyte transcriptome

amino acid metabolic disorder

Disease
Source: DOID:9252
Definition: An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids.
Genes: Echs1 (Mmu)...ECHS1 (Hsa)...echs1 (Xtr)...Echs1 (Rno)...Echs1 (Dme)
Alleles: Echs1 (Dme)

fatty acid beta-oxidation

Gene Ontology
Source: GO:0006635
Synonyms: Not Available
Branch: biological process
Genes: Echs1 (Mmu)...ECHS1 (Hsa)...Echs1 (Rno)...Echs1 (Dme)...echs1 (Dre)

branched-chain amino acid catabolic process

Gene Ontology
Source: GO:0009083
Synonyms:
  • branched chain family amino acid breakdown
  • branched chain family amino acid catabolic process
Branch: biological process
Genes: ECHS1 (Hsa)

Hsap\ECHS1UAS.cMa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0406763
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\ECHS1
Construct Expressed Component: ECHS1 (Hsa)

Scer\GAL4Echs1-CR00484-TG4.1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0341106
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Scer\GAL4<Echs1-CR00484-TG4.1>

lyase activity

Gene Ontology
Source: GO:0016829
Synonyms: Not Available
Branch: molecular function
Genes: ECHS1 (Hsa)...Echs1 (Rno)...echs1 (Dre)

catalytic activity

Gene Ontology
Source: GO:0003824
Synonyms:
  • enzyme activity
Branch: molecular function
Genes: ECHS1 (Hsa)...Echs1 (Dme)...echs1 (Dre)

isomerase activity

Gene Ontology
Source: GO:0016853
Synonyms:
  • other isomerase activity
Branch: molecular function
Genes: ECHS1 (Hsa)

fatty acid metabolic process

Gene Ontology
Source: GO:0006631
Synonyms:
  • fatty acid metabolism
Branch: biological process
Genes: ECHS1 (Hsa)

mitochondrial matrix

Gene Ontology
Source: GO:0005759
Synonyms:
  • mitochondrial lumen
  • mitochondrial stroma
Branch: cellular component
Genes: ECHS1 (Hsa)...Echs1 (Mmu)...Echs1 (Rno)

(R6)2R:13853154T>A

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13853154T>A
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)2R:13853154T>A
Gene Synonyms: Echs1

(R6)2R:13853259C>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13853259C>G
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)2R:13853259C>G
Gene Synonyms: Echs1

(R6)2R:13853634G>A

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13853634G>A
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)2R:13853634G>A
Gene Synonyms: Echs1

(R6)2R:13854127C>T

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13854127C>T
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)2R:13854127C>T
Gene Synonyms: Echs1

(R6)2R:13853532T>G

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13853532T>G
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)2R:13853532T>G
Gene Synonyms: Echs1

(R6)2R:13853739G>A

(Drosophila melanogaster)
Allele/Variant
Source: NT_033778.4:g.13853739G>A
Genes: Echs1 (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)2R:13853739G>A
Gene Synonyms: Echs1