Version: 8.1.0Date: Fri Apr 18 2025
Category
eif-2Bepsilon
(Caenorhabditis elegans)Gene
Name: Eukaryotic Initiation Factor 2Bepsilon
Synonyms: CELE_D2085.3, D2085.3
Source: WB:WBGene00008428
Biotype: protein coding gene
Symbol: eif-2Bepsilon (Cel)
Symbol: eif-2Bepsilon
Cross References: eif-2Bepsilon...WB:eif-2Bepsilon...eif-2Bepsilon
eIF2Bε
(Drosophila melanogaster)Gene
Name: eukaryotic translation initiation factor 2B subunit epsilon
Synonyms: eIF2B-epsilon, elf2B-epsilon, eIF-2bepsilon, CG3806, eIF2Bepsilon, EG:86E4.1
Source: FB:FBgn0023512
Biotype: protein coding gene
Synonyms: eIF-2bepsilon...eIF-2bepsilon...eIF-2bepsilon
Strict Orthology Symbols: eif-2Bepsilon
EIF2B5
(Homo sapiens)Gene
Name: eukaryotic translation initiation factor 2B subunit epsilon
Synonyms: translation initiation factor eIF2B subunit epsilon, VWM5, eIF-2B GDP-GTP exchange factor subunit epsilon, LVWM, initiation factor eif-2be, eIF2B GDP-GTP exchange factor subunit epsilon, translation initiation factor eIF-2B subunit epsilon, EIF-2B, EIF2Bepsilon, CACH, CLE, eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Source: HGNC:3261
Biotype: protein coding gene
Strict Orthology Symbols: eif-2Bepsilon
Eif2b5
(Rattus norvegicus)Gene
Name: eukaryotic translation initiation factor 2B subunit epsilon
Synonyms: eukaryotic translation initiation factor 2B subunit 5 epsilon, eukaryotic translation initiation factor 2B, subunit 5 epsilon, eukaryotic translation initiation factor 2B subunit 5, translation initiation factor eIF2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon, eIF2B GDP-GTP exchange factor subunit epsilon, initiation factor eIF-2Be, translation initiation factor eIF-2B subunit epsilon, LOC192234
Source: RGD:708380
Biotype: protein coding gene
Strict Orthology Symbols: eif-2Bepsilon
eif2b5
(Danio rerio)Gene
Name: eukaryotic translation initiation factor 2B, subunit 5 epsilon
Synonyms: fd14g07, wu:fd14g07
Source: ZFIN:ZDB-GENE-030131-5364
Biotype: protein coding gene
Strict Orthology Symbols: eif-2Bepsilon
Eif2b5
(Mus musculus)Gene
Name: eukaryotic translation initiation factor 2B, subunit 5 epsilon
Synonyms: expressed sequence C81315, C81315
Source: MGI:2446176
Biotype: protein coding gene
Strict Orthology Symbols: eif-2Bepsilon
GCD6
(Saccharomyces cerevisiae)Gene
Name: General Control Derepressed
Synonyms: YDR211W
Source: SGD:S000002619
Biotype: protein coding gene
Strict Orthology Symbols: eif-2Bepsilon
eif2b5
(Xenopus tropicalis)Gene
Name: eukaryotic translation initiation factor 2B subunit epsilon
Synonyms: eif2b5, eukaryotic translation initiation factor 2B subunit epsilon
Source: Xenbase:XB-GENE-986286
Biotype: gene
Strict Orthology Symbols: eif-2Bepsilon
Source: DOID:0070367
Definition: A leukoencephalopathy with vanishing white matter that has_material_basis_in homozygous or compound heterozygous mutation in the EIF2B5 gene on chromosome 3q27.
Genes: eif-2Bepsilon (Cel)
Gene Ontology
Source: GO:0005851
Synonyms:
- eIF-2B
- eif2B
Branch: cellular component
Genes: eif-2Bepsilon (Cel)
Source: DOID:0060868
Definition: A leukodystrophy characterized by variable neurologic features resulting from deficiency in astrocyte maturation, including progressive cerebellar ataxia, spasticity, and cognitive impairment associated with white matter lesions on brain imaging with onset from early infancy to adulthood.
Genes: eif-2Bepsilon (Cel)
Gene Ontology
Source: GO:0031369
Synonyms: Not Available
Branch: molecular function
Genes: eif-2Bepsilon (Cel)
Gene Ontology
Source: GO:0003743
Synonyms: Not Available
Branch: molecular function
Genes: eif-2Bepsilon (Cel)
Gene Ontology
Source: GO:0006413
Synonyms:
- biopolymerisation
- biopolymerization
Branch: biological process
Genes: eif-2Bepsilon (Cel)
Gene Ontology
Source: GO:0005085
Synonyms:
- ARF guanyl-nucleotide exchange factor activity
- GDP-dissociation stimulator activity
Branch: molecular function
Genes: eif-2Bepsilon (Cel)
(R6)X:1921857A>G
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921857A>G
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921857A>G
Gene Synonyms: eIF-2bepsilon
(R6)X:1920518A>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1920518A>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)X:1920518A>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1920802T>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1920802T>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1920802T>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922617C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922617C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922617C>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922671C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922671C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922671C>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922686T>G
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922686T>G
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922686T>G
Gene Synonyms: eIF-2bepsilon
(R6)X:1921075G>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921075G>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921075G>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922700A>C
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922700A>C
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922700A>C
Gene Synonyms: eIF-2bepsilon
(R6)X:1921623T>C
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921623T>C
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921623T>C
Gene Synonyms: eIF-2bepsilon
(R6)X:1920773G>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1920773G>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (R6)X:1920773G>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1921854C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921854C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921854C>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922665G>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922665G>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, start_lost, synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922665G>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1922049C>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922049C>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922049C>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1922528C>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922528C>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922528C>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1921629G>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921629G>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921629G>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1921727A>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921727A>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)X:1921727A>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1922503A>G
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922503A>G
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922503A>G
Gene Synonyms: eIF-2bepsilon
(R6)X:1922019C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922019C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922019C>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922100A>G
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922100A>G
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922100A>G
Gene Synonyms: eIF-2bepsilon
(R6)X:1922584C>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922584C>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922584C>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1921812T>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921812T>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921812T>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1922797A>C
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922797A>C
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)X:1922797A>C
Gene Synonyms: eIF-2bepsilon
(R6)X:1921947T>C
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921947T>C
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921947T>C
Gene Synonyms: eIF-2bepsilon
(R6)X:1922482C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922482C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (R6)X:1922482C>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1920744T>C
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1920744T>C
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1920744T>C
Gene Synonyms: eIF-2bepsilon
(R6)X:1921210G>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921210G>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)X:1921210G>A
Gene Synonyms: eIF-2bepsilon
(R6)X:1921471T>G
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921471T>G
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (R6)X:1921471T>G
Gene Synonyms: eIF-2bepsilon
(R6)X:1922160C>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922160C>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1922160C>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1920550G>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1920550G>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)X:1920550G>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1921872G>T
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1921872G>T
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (R6)X:1921872G>T
Gene Synonyms: eIF-2bepsilon
(R6)X:1922840C>A
(Drosophila melanogaster)Allele/Variant
Source: NC_004354.4:g.1922840C>A
Genes: eIF2Bε (Dme)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (R6)X:1922840C>A
Gene Synonyms: eIF-2bepsilon
(WBcel235)II:8662345G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003280.10:g.8662345G>A
Genes: eif-2Bepsilon (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:8662345G>A
Gene Cross References: eif-2Bepsilon
(WBcel235)II:8664619C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003280.10:g.8664619C>T
Genes: eif-2Bepsilon (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)II:8664619C>T
Gene Cross References: eif-2Bepsilon
(WBcel235)II:8663298C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003280.10:g.8663298C>T
Genes: eif-2Bepsilon (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:8663298C>T
Gene Cross References: eif-2Bepsilon
(WBcel235)II:8663849T>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003280.10:g.8663849T>C
Genes: eif-2Bepsilon (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:8663849T>C
Gene Cross References: eif-2Bepsilon