Version: 8.0.0Date: Tue Jan 28 2025
Category
FBXO43
(Homo sapiens)Gene
Name: F-box protein 43
Synonyms: SPGF64, EMI2, endogenous meiotic inhibitor 2, early mitotic inhibitor 2, Fbx43, OOMD12, F-box only protein 43, ERP1, OZEMA12
Source: HGNC:28521
Biotype: protein coding gene
Symbol: FBXO43 (Hsa)
Symbol: FBXO43
Strict Orthology Symbols: fbxo43
fbxo43
(Danio rerio)Gene
Name: F-box protein 43
Synonyms: zgc:66488
Source: ZFIN:ZDB-GENE-040426-1645
Biotype: protein coding gene
Symbol: fbxo43 (Dre)
Symbol: fbxo43
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Strict Orthology Symbols: fbxo43
Fbxo43
(Mus musculus)Gene
Name: F-box protein 43
Synonyms: Emi2, RIKEN cDNA 4930533G20 gene, endogenous meiotic inhibitor 2, early mitotic inhibitor 2, 4930533G20Rik, XErp1 homolog
Source: MGI:1926053
Biotype: protein coding gene
Symbol: Fbxo43 (Mmu)
Symbol: Fbxo43
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Strict Orthology Symbols: fbxo43
Alleles: Fbxo43
Fbxo43
(Rattus norvegicus)Gene
Name: F-box protein 43
Synonyms: endogenous meiotic inhibitor 2, F-box only protein 43, LOC315034
Source: RGD:1310225
Biotype: protein coding gene
Symbol: Fbxo43 (Rno)
Symbol: Fbxo43
Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43); INTERACTS WITH acrylamide; bisphenol A; gentamycin.
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Strict Orthology Symbols: fbxo43
fbxo43
(Xenopus tropicalis)Gene
Name: F-box protein 43
Synonyms: erp1, Xerp1, F-box protein 43, fbxo43, fbx26, emi2
Source: Xenbase:XB-GENE-951946
Biotype: gene
Symbol: fbxo43
Symbol: fbxo43 (Xtr)
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Synonyms: fbxo43...fbxo43...fbxo43
Strict Orthology Symbols: fbxo43
fbxo43.S
(Xenopus laevis)Gene
Name: F-box protein 43
Synonyms: Xerp1, erp1, F-box protein 43, fbxo43.S, fbx26, emi2
Source: Xenbase:XB-GENE-17330026
Biotype: gene
Symbol: fbxo43.S (Xla)
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Strict Orthology Symbols: fbxo43
Symbol: fbxo43.S
fbxo43.L
(Xenopus laevis)Gene
Name: F-box protein 43
Synonyms: Xerp1, erp1, F-box protein 43, fbxo43.L, fbx26, emi2
Source: Xenbase:XB-GENE-951950
Biotype: gene
Symbol: fbxo43.L (Xla)
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43).
Strict Orthology Symbols: fbxo43
Symbol: fbxo43.L
Fbxo43tm1.1Kald
(Mus musculus)Allele/Variant
Source: MGI:6201341
Genes: Fbxo43 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Fbxo43
Genes: Fbxo43 (Mmu)
Symbol: Fbxo43tm1.1Kald
Fbxo43tm1.2Kald
(Mus musculus)Allele/Variant
Source: MGI:6201342
Genes: Fbxo43 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Fbxo43
Genes: Fbxo43 (Mmu)
Symbol: Fbxo43tm1.2Kald
Fbxo43em2Gpt
(Mus musculus)Allele/Variant
Source: MGI:7299022
Genes: Fbxo43 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Fbxo43
Genes: Fbxo43 (Mmu)
Symbol: Fbxo43em2Gpt
Fbxo43em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7299021
Genes: Fbxo43 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Fbxo43
Genes: Fbxo43 (Mmu)
Symbol: Fbxo43em1Gpt
Model
Id: MGI:6201521
Synonyms: Not Available
Symbol: Fbxo43/Fbxo43 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> [background:] involves
Genes: Fbxo43 (Mmu)
Alleles: Fbxo43
Name: Fbxo43/Fbxo43 Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> [background:] involves
Fbxo43tm1.1Kald/Fbxo43tm1.1Kald Tg(Stra8-icre)1Reb/0 [background:] involves: 129 * C57BL/6 * FVB/NJ * SJL
(Mus musculus)Model
Id: MGI:6201523
Synonyms: Not Available
Symbol: Fbxo43/Fbxo43 Tg(Stra8-icre)1Reb/0 [background:] involves: 129 * C57BL/6 * FVB
Genes: Fbxo43 (Mmu)
Alleles: Fbxo43
Name: Fbxo43/Fbxo43 Tg(Stra8-icre)1Reb/0 [background:] involves: 129 * C57BL/6 * FVB
Model
Id: MGI:6201524
Synonyms: Not Available
Symbol: Fbxo43/Fbxo43 [background:] involves: 129 * C57BL/6 * FVB/N * SJL (Mmu)
Genes: Fbxo43 (Mmu)
Alleles: Fbxo43
Name: Fbxo43/Fbxo43 [background:] involves: 129 * C57BL/6 * FVB/N * SJL
Rca1
(Drosophila melanogaster)Gene
Name: Regulator of cyclin A1
Synonyms: l(2)03300, CLD4, RCA1, CG10800, P3300, Emi1, S(rux)2A, rca1, Regulator of Cyclin A 1, regulator of cyclin A, FBXO5, Suppressor of rux 2A, 152549_at, regulator of Cyclin A
Source: FB:FBgn0017551
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human FBXO43 (F-box protein 43) and FBXO5 (F-box protein 5).
Strict Orthology Symbols: fbxo43
Disease
Source: DOID:0112353
Definition: A spermatogenic failure characterized by male infertility due to oligoasthenoteratozoospermia or nonobstructive azoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the FBXO43 gene on chromosome 8q22.2.
Genes: Fbxo43 (Mmu)...Fbxo43 (Rno)...fbxo43 (Dre)...fbxo43 (Xtr)...FBXO43 (Hsa)
Gene Ontology
Source: GO:0010948
Synonyms: Not Available
Branch: biological process
Genes: Fbxo43 (Rno)...Fbxo43 (Mmu)...FBXO43 (Hsa)
Gene Ontology
Source: GO:0045835
Synonyms:
- down regulation of meiosis
- down-regulation of meiosis
Branch: biological process
Genes: Fbxo43 (Rno)...Fbxo43 (Mmu)...fbxo43 (Dre)...FBXO43 (Hsa)
Gene Ontology
Source: GO:0140013
Synonyms:
- meiosis
Branch: biological process
Genes: Fbxo43 (Mmu)...Fbxo43 (Rno)...FBXO43 (Hsa)
Gene Ontology
Source: GO:0040020
Synonyms:
- regulation of meiosis
Branch: biological process
Genes: Fbxo43 (Rno)...Fbxo43 (Mmu)...FBXO43 (Hsa)
Model
Id: MGI:6201527
Synonyms: Not Available
Genes: Fbxo43 (Mmu)
Alleles: Fbxo43
Name: Cdk1/Cdk1<+> Fbxo43/Fbxo43 Gt(ROSA)26Sor/Gt(ROSA)26Sor
Symbol: Cdk1/Cdk1<+> Fbxo43/Fbxo43 Gt(ROSA)26Sor/Gt(ROSA)26Sor
Gene Ontology
Source: GO:0001674
Synonyms:
- female germ-cell nucleus
Branch: cellular component
Genes: FBXO43 (Hsa)...Fbxo43 (Rno)...Fbxo43 (Mmu)
Gene Ontology
Source: GO:0007088
Synonyms:
- regulation of mitosis
Branch: biological process
Genes: FBXO43 (Hsa)...fbxo43 (Dre)...Fbxo43 (Rno)...Fbxo43 (Mmu)
Gene Ontology
Source: GO:0042177
Synonyms:
- down regulation of cellular protein breakdown
- down regulation of cellular protein catabolic process
Branch: biological process
Genes: FBXO43 (Hsa)...Fbxo43 (Rno)...Fbxo43 (Mmu)
Gene Ontology
Source: GO:0030163
Synonyms:
- cellular protein breakdown
- cellular protein catabolic process
Branch: biological process
Genes: Fbxo43 (Rno)...FBXO43 (Hsa)...Fbxo43 (Mmu)
Gene Ontology
Source: GO:0016567
Synonyms:
- protein ubiquitinylation
- protein ubiquitylation
Branch: biological process
Genes: Fbxo43 (Mmu)...FBXO43 (Hsa)...Fbxo43 (Rno)...fbxo43 (Dre)
Gene Ontology
Source: GO:0051321
Synonyms:
- meiosis
Branch: biological process
Genes: FBXO43 (Hsa)
Gene Ontology
Source: GO:0008270
Synonyms:
- Zn binding
- zinc binding
Branch: molecular function
Genes: Fbxo43 (Mmu)...FBXO43 (Hsa)...Fbxo43 (Rno)
sa13745
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-131217-12170
Genes: fbxo43 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: fbxo43 (Dre)
Gene Ontology
Source: GO:0046872
Synonyms:
- heavy metal binding
- metal binding
Branch: molecular function
Genes: FBXO43 (Hsa)...fbxo43 (Dre)
Gene Ontology
Source: GO:0005515
Synonyms:
- glycoprotein binding
- protein amino acid binding
Branch: molecular function
Genes: FBXO43 (Hsa)...Fbxo43 (Mmu)
(GRCh38)8:100142126G>A
(Homo sapiens)Allele/Variant
Source: rs754320394
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100142126G>A
(GRCh38)8:100134292G>A
(Homo sapiens)Allele/Variant
Source: rs768989830
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: stop_gained, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100134292G>A
(GRCh38)8:100140700G>C
(Homo sapiens)Allele/Variant
Source: rs199780921
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140700G>C
(GRCh38)8:100140884C>A
(Homo sapiens)Allele/Variant
Source: rs954142586
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140884C>A
(GRCh38)8:100141572A>C
(Homo sapiens)Allele/Variant
Source: rs373258172
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141572A>C
(GRCh38)8:100140700G>A
(Homo sapiens)Allele/Variant
Source: rs199780921
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140700G>A
(GRCh38)8:100134364C>T
(Homo sapiens)Allele/Variant
Source: rs373092371
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100134364C>T
(GRCh38)8:100141395C>T
(Homo sapiens)Allele/Variant
Source: rs1171227939
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141395C>T
(GRCh38)8:100133950C>T
(Homo sapiens)Allele/Variant
Source: rs370561864
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100133950C>T
(GRCh38)8:100137646A>T
(Homo sapiens)Allele/Variant
Source: rs759048586
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100137646A>T
(GRCh38)8:100141337A>G
(Homo sapiens)Allele/Variant
Source: rs376577612
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141337A>G
(GRCh38)8:100141707C>T
(Homo sapiens)Allele/Variant
Source: rs748362105
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141707C>T
(GRCh38)8:100133938C>T
(Homo sapiens)Allele/Variant
Source: rs954702094
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100133938C>T
(GRCh38)8:100140744T>C
(Homo sapiens)Allele/Variant
Source: NC_000008.11:g.100140744T>C
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140744T>C
(GRCh38)8:100140843C>T
(Homo sapiens)Allele/Variant
Source: rs1215477131
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140843C>T
(GRCh38)8:100140915G>A
(Homo sapiens)Allele/Variant
Source: rs373156415
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140915G>A
(GRCh38)8:100140986C>T
(Homo sapiens)Allele/Variant
Source: rs748943275
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100140986C>T
(GRCh38)8:100141205T>C
(Homo sapiens)Allele/Variant
Source: rs530844525
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141205T>C
(GRCh38)8:100141209A>T
(Homo sapiens)Allele/Variant
Source: rs373910464
Genes: FBXO43 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)8:100141209A>T