Version: 8.0.0Date: Tue Jan 28 2025
Category
Gdf5
(Mus musculus)Gene
Name: growth differentiation factor 5
Synonyms: brp, cartilage-derived morphogenetic protein-1, Cdmp1, brachypodism, bp, brachypod Japan, CDMP-1
Source: MGI:95688
Biotype: protein coding gene
Symbol: Gdf5 (Mmu)
Symbol: Gdf5
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Strict Orthology Symbols: gdf5
Alleles: Gdf5
gdf5
(Danio rerio)Gene
Name: growth differentiation factor 5
Synonyms: bmp14, ctc, e1gdf5, contact
Source: ZFIN:ZDB-GENE-990415-39
Biotype: protein coding gene
Symbol: gdf5 (Dre)
Symbol: gdf5
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Strict Orthology Symbols: gdf5
Gdf5
(Rattus norvegicus)Gene
Name: growth differentiation factor 5
Synonyms: Cdmp1, cartilage-derived morphogenetic protein 1, growth/differentiation factor 5
Source: RGD:620102
Biotype: protein coding gene
Symbol: Gdf5 (Rno)
Symbol: Gdf5
Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5); PARTICIPATES IN transforming growth factor-beta
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Strict Orthology Symbols: gdf5
GDF5
(Homo sapiens)Gene
Name: growth differentiation factor 5
Synonyms: SYM1B, cartilage-derived morphogenetic protein 1, lipopolysaccharide-associated protein 4, radotermin, growth/differentiation factor 5, BMP-14, BMP14, LAP-4, BDA1C, OS5, cartilage-derived morphogenetic protein-1, GDF-5, LAP4, DUPANS, bone morphogenetic protein 14, LPS-associated protein 4, SYNS2, CDMP1, CDMP-1
Source: HGNC:4220
Biotype: protein coding gene
Symbol: GDF5 (Hsa)
Symbol: GDF5
Strict Orthology Symbols: gdf5
gdf5
(Xenopus tropicalis)Gene
Name: growth differentiation factor 5
Synonyms: growth differentiation factor 5, gdf, gdf-5, gdf5, CDMP1
Source: Xenbase:XB-GENE-481784
Biotype: gene
Symbol: gdf5
Symbol: gdf5 (Xtr)
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Synonyms: gdf5...gdf5...gdf5
Strict Orthology Symbols: gdf5
GDF5-AS1
(Homo sapiens)Gene
Name: GDF5 antisense RNA 1
Synonyms: GDF5OS, growth differentiation factor 5 opposite strand
Source: HGNC:33435
Biotype: ncRNA gene
Symbol: GDF5-AS1 (Hsa)
Symbol: GDF5-AS1
gdf5.L
(Xenopus laevis)Gene
Name: growth differentiation factor 5
Synonyms: growth differentiation factor 5, gdf, gdf5.L, gdf-5, CDMP1
Source: Xenbase:XB-GENE-481788
Biotype: gene
Symbol: gdf5.L (Xla)
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Strict Orthology Symbols: gdf5
Symbol: gdf5.L
gdf5.S
(Xenopus laevis)Gene
Name: growth differentiation factor 5
Synonyms: growth differentiation factor 5, gdf5.S, gdf, gdf-5, CDMP1
Source: Xenbase:XB-GENE-17335085
Biotype: gene
Symbol: gdf5.S (Xla)
Automated Gene Synopsis: Orthologous to human GDF5 (growth differentiation factor 5).
Strict Orthology Symbols: gdf5
Symbol: gdf5.S
Gdf5bp-4J
(Mus musculus)Allele/Variant
Source: MGI:4847635
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp-4J
Gdf5png
(Mus musculus)Allele/Variant
Source: MGI:3847115
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5png
Gdf5em2Cya
(Mus musculus)Allele/Variant
Source: MGI:7583978
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5em2Cya
Gdf5bp-J
(Mus musculus)Allele/Variant
Source: MGI:1855974
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp-J
Gdf5em2(IMPC)H
(Mus musculus)Allele/Variant
Source: MGI:6414523
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5em2(IMPC)H
Gdf5em1(IMPC)Bay
(Mus musculus)Allele/Variant
Source: MGI:7425707
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5em1(IMPC)Bay
Gdf5tm1a(EUCOMM)Hmgu
(Mus musculus)Allele/Variant
Source: MGI:5555125
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5tm1a(EUCOMM)Hmgu
Gdf5em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7376610
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5em1Gpt
Gdf5tm1.1(cre/ERT2)Eze
(Mus musculus)Allele/Variant
Source: MGI:5789619
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5tm1.1(cre/ERT2)Eze
Construct Regulatory Region: Gdf5 (Mmu)
Constructs: Gdf5< construct
Gdf5tm1c(EUCOMM)Hmgu
(Mus musculus)Allele/Variant
Source: MGI:7779631
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5tm1c(EUCOMM)Hmgu
Gdf5em1(IMPC)H
(Mus musculus)Allele/Variant
Source: MGI:6414491
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5em1(IMPC)H
Gdf5brp
(Mus musculus)Allele/Variant
Source: MGI:1856810
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5brp
Gdf5bp-3J
(Mus musculus)Allele/Variant
Source: MGI:1856340
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp-3J
Gdf5bp-H
(Mus musculus)Allele/Variant
Source: MGI:1855973
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp-H
Gdf5bp
(Mus musculus)Allele/Variant
Source: MGI:1855972
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp
Gdf5bp-6J
(Mus musculus)Allele/Variant
Source: MGI:5695012
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5bp-6J
Model
Id: MGI:3758631
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] C57BL/6JJcl-Gdf5 (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] C57BL/6JJcl-Gdf5
Gdf5bp-J/Gdf5bp-J Gdf6tm1Kng/Gdf6tm1Kng [background:] involves: 129S1/Sv * 129X1/SvJ * A/J * C57BL/6J
(Mus musculus)Model
Id: MGI:2661079
Synonyms: Not Available
Symbol: Gdf5/Gdf5 Gdf6/Gdf6 [background:] involves: 129S1/Sv * 129X1/SvJ * A/J *
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 Gdf6/Gdf6 [background:] involves: 129S1/Sv * 129X1/SvJ * A/J *
Gdf5Rgsc451/Gdf5+ [background:] C57BL/6JJcl-Gdf5Rgsc451
(Mus musculus)Model
Id: MGI:3758632
Synonyms: Not Available
Symbol: Gdf5/Gdf5<+> [background:] C57BL/6JJcl-Gdf5 (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5<+> [background:] C57BL/6JJcl-Gdf5
Gdf5Bp-5J/Gdf5+ [background:] C57BL/6J-Gdf5Bp-5J/GrsrJ
(Mus musculus)Model
Id: MGI:5509382
Synonyms: Not Available
Symbol: Gdf5/Gdf5<+> [background:] C57BL/6J-Gdf5/GrsrJ (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5<+> [background:] C57BL/6J-Gdf5/GrsrJ
Gdf5png/Gdf5png [background:] C57BL/6Apb-Gdf5png/AnuApb
(Mus musculus)Model
Id: MGI:3847116
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] C57BL/6Apb-Gdf5/AnuApb (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] C57BL/6Apb-Gdf5/AnuApb
Model
Id: MGI:4847654
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] involves: PCT stock * Swiss albino (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] involves: PCT stock * Swiss albino
Gdf5bp-J/Gdf5+ [background:] A/J-Gdf5bp-J/J
(Mus musculus)Model
Id: MGI:3789179
Synonyms: Not Available
Symbol: Gdf5/Gdf5<+> [background:] A/J-Gdf5/J (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5<+> [background:] A/J-Gdf5/J
Gdf5bp-J/Gdf5bp-J [background:] A/J-Gdf5bp-J/J
(Mus musculus)Model
Id: MGI:3702968
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] A/J-Gdf5/J (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] A/J-Gdf5/J
Gdf5bp-3J/Gdf5bp-3J [background:] involves: BALB/cJ
(Mus musculus)Model
Id: MGI:2168885
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] involves: BALB/cJ (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] involves: BALB/cJ
Gdf5bp-4J/Gdf5bp-4J [background:] B6.Cg-Gdf5bp-4J/GrsrJ
(Mus musculus)Model
Id: MGI:5450849
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] B6.Cg-Gdf5/GrsrJ (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] B6.Cg-Gdf5/GrsrJ
gdf5uu3703/uu3703 (AB)
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-221024-1
Synonyms: Not Available
Symbol: gdf5
Genes: gdf5 (Dre)
Name: gdf5 (AB)
Gdf5brp/Gdf5brp [background:] involves: NC
(Mus musculus)Model
Id: MGI:2658810
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] involves: NC (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] involves: NC
Model
Id: MGI:7414904
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] C57BL/6NTac-Gdf5/H (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] C57BL/6NTac-Gdf5/H
Gdf5bp-H/Gdf5bp-H [background:] involves: PCT
(Mus musculus)Model
Id: MGI:5003466
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] involves: PCT (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] involves: PCT
Gdf5bp-6J/Gdf5bp-6J [background:] DBA/2J-Gdf5bp-6J/GrsrJ
(Mus musculus)Model
Id: MGI:5695866
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] DBA/2J-Gdf5/GrsrJ (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] DBA/2J-Gdf5/GrsrJ
Model
Id: MGI:7472016
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] C57BL/6N-Gdf5/BayMmucd (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] C57BL/6N-Gdf5/BayMmucd
Gdf5bp/Gdf5bp [background:] Swiss albino stock
(Mus musculus)Model
Id: MGI:3693971
Synonyms: Not Available
Symbol: Gdf5/Gdf5 [background:] Swiss albino stock (Mmu)
Genes: Gdf5 (Mmu)
Alleles: Gdf5
Name: Gdf5/Gdf5 [background:] Swiss albino stock
Gdf5Rgsc451
(Mus musculus)Allele/Variant
Source: MGI:3699319
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: osteoarthritis
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5Rgsc451
Gdf5Bp-5J
(Mus musculus)Allele/Variant
Source: MGI:5502183
Genes: Gdf5 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant, 5_prime_UTR_variant
Diseases: brachydactyly type C, multiple synostoses syndrome, brachydactyly type A2, acromesomelic dysplasia, Hunter-Thompson type, brachydactyly type A1C, fibular hypoplasia and complex brachydactyly, acromesomelic dysplasia, Grebe type
Variant Name: Not Available
Symbol: Gdf5
Genes: Gdf5 (Mmu)
Symbol: Gdf5Bp-5J
Source: DOID:0060931
Definition: A developmental dysplasia of the hip that is characterized by a shallow hip socket and that has_material_basis_in variation in the chromosomal region 13q22.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)
Source: DOID:0081318
Definition: A multiple synostoses syndrome that is characterized by progressive joint fusions of the fingers, wrists, ankles, and cervical spine; characteristic facies, including a broad hemicylindrical nose; and progressive conductive hearing loss and that has_material_basis_in heterozygous mutation in the GDF5 gene on chromosome 20q11.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)
Disease
Source: DOID:0110977
Definition: A brachydactyly type A1 has_material_basis_in homozygous or heterozygous mutation in the GDF5 gene on chromosome 20q11.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)
Alleles: Gdf5
Source: DOID:0050790
Definition: An acromesomelic dysplasia that is characterized by severe reduction or absence of the fibula and complex brachydactyly.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)
Alleles: Gdf5
Source: DOID:0080051
Definition: An acromesomelic dysplasia that has_material_basis_in mutation in AMDH gene which results_in normal axial skeleton but fused bones in the located_in hand or located_in foot.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)
Alleles: Gdf5
Disease
Source: DOID:0110964
Definition: A brachydactyly characterized by rudimentary or fused middle phalanges of all the digits and shortened proximal phalanges of the thumbs and big toes.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...gdf5.L (Xla)...Gdf5 (Rno)
Source: DOID:0081317
Definition: A multiple synostoses syndrome is characterized by multiple joint fusions, usually commencing in the hands, conductive deafness, and characteristic facial features, including a broad, tubular-shaped nose and a thin upper vermilion and that has_material_basis_in heterozygous mutation in the NOG gene on chromosome 17q22.
Genes: gdf5.S (Xla)...gdf5 (Xtr)...Gdf5 (Mmu)...Gdf5 (Rno)...GDF5 (Hsa)