Version: 8.0.0Date: Tue Jan 28 2025
Category
Disease
Source: DOID:0080530
Definition: A granular corneal dystrophy that is characterized by recurrent erosions and gray crumb-like opacification located_in the cornea, proteinaceous rock candy-like deposits in the anterior stroma and subepithelium, and progressive vision loss later in life as deposits move into the central vision, and has_material_basis_in autosomal dominant inheritance of heterozygous mutation of transforming growth factor beta-induced gene located in chromosome 5q31.1, which encodes keratoepithelin. Abnormalities lead to increased protein deposition and disruption of the corneal surface.
Symbol: granular corneal dystrophy 1
Source: DOID:5047
Definition: A posterior pituitary gland neoplasm that arises from the neurohypophysis or infundibulum. It is composed of nests of large cells with granular, eosinophilic cytoplasm due to abundant intracytoplasmic lysosomes.
Symbol: granular cell tumor of the sellar region
Disease
Source: DOID:0060444
Definition: An corneal granular dystrophy that is characterized by recurrent erosions and stellate or thorn-like opacification located_in the cornea, hyaline and amyloid deposits in the stroma, and progressive vision loss later in life, and has_material_basis_in autosomal dominant inheritance of mutation of transforming growth factor beta-induced gene on chromosome 5q31.1, which encodes keratoepithelin. Abnormalities lead to increased hyaline and amyloid protein deposition and disruption of the corneal surface.
Symbol: granular corneal dystrophy 2
Source: GO:0038158
Synonyms:
- CSF3 signaling pathway
- G-CSF receptor signaling pathway
Branch: biological process
Symbol: granulocyte colony-stimulating factor signaling pathway
Gene Ontology
Source: GO:0090391
Synonyms:
- grana formation
Branch: biological process
Symbol: granum assembly
Gene Ontology
Source: GO:0060015
Synonyms: Not Available
Branch: biological process
Symbol: granulosa cell fate commitment
Source: GO:0140507
Synonyms:
- granzyme-mediated cell death signaling pathway
Branch: biological process
Symbol: granzyme-mediated programmed cell death signaling pathway
Source: GO:0042021
Synonyms:
- GM-CSF complex binding
- GMC-SF complex binding
Branch: molecular function
Symbol: granulocyte macrophage colony-stimulating factor complex binding
Disease
Source: DOID:4903
Definition: A carcinoma that derives_from epithelial cells, with polygonal accumulation of secondary lysosomes in the cytoplasm.
Symbol: granular cell carcinoma
Disease
Source: DOID:4038
Definition: Not Available
Symbol: granulomatous gastritis
Disease
Source: DOID:5258
Definition: A leiomyosarcoma that is characterized by a proliferation of cells containing abundant granular eosinophilic cytoplasm.
Symbol: granular cell leiomyosarcoma
Disease
Source: DOID:2999
Definition: A sex cord-gonadal stromal tumor that has_material_basis_in granulosa cells and arises from the sex cord stroma.
Symbol: granulosa cell tumor
Disease
Source: DOID:2555
Definition: Not Available
Symbol: granulomatous angiitis
Disease
Source: DOID:2239
Definition: Not Available
Symbol: granulomatous hepatitis
Disease
Source: DOID:4561
Definition: An endometritis that is characterized by the presence of granulomas in the uterus.
Symbol: granulomatous endometritis
Gene Ontology
Source: GO:0097530
Synonyms: Not Available
Branch: biological process
Symbol: granulocyte migration
Source: GO:0038157
Synonyms:
- CSF2 signaling pathway
- GM-CSF receptor signaling pathway
Branch: biological process
Symbol: granulocyte-macrophage colony-stimulating factor signaling pathway
Gene Ontology
Source: GO:0071621
Synonyms: Not Available
Branch: biological process
Symbol: granulocyte chemotaxis
Disease
Source: DOID:12318
Definition: An epithelial-stromal TGFBI dystrophy that is characterized by progressive accumulation of deposits within the layers of the cornea.
Symbol: granular corneal dystrophy
Disease
Source: DOID:3428
Definition: Not Available
Symbol: granulomatous myositis
Gene Ontology
Source: GO:1990739
Synonyms: Not Available
Branch: biological process
Symbol: granulosa cell proliferation
Gene Ontology
Source: GO:0001652
Synonyms:
- pars granulosa
Branch: cellular component
Symbol: granular component
Gene Ontology
Source: GO:0060016
Synonyms: Not Available
Branch: biological process
Symbol: granulosa cell development
Gene Ontology
Source: GO:0033380
Synonyms:
- granzyme B localisation in T cell secretory granule
- granzyme B localization in T cell secretory granule
Branch: biological process
Symbol: granzyme B localization to T cell secretory granule
Source: GO:0032604
Synonyms:
- GM-CSF production
- granulocyte macrophage colony stimulating factor production
Branch: biological process
Symbol: granulocyte macrophage colony-stimulating factor production
Gene Ontology
Source: GO:0030851
Synonyms:
- granulocyte cell differentiation
Branch: biological process
Symbol: granulocyte differentiation
Source: GO:0005130
Synonyms:
- G-CSF receptor ligand
- GC-SF receptor ligand
Branch: molecular function
Symbol: granulocyte colony-stimulating factor receptor binding
Gene Ontology
Source: GO:1901108
Synonyms:
- granaticin breakdown
- granaticin catabolism
Branch: biological process
Symbol: granaticin catabolic process
Source: DOID:0050246
Definition: A parasitic protozoa infectious disease that results in infection of the brain caused by Acanthamoeba or Balamuthia mandrillaris. The symptoms include headaches, altered mental status, and focal neurologic deficit, which progresses over several weeks to death.
Symbol: granulomatous amebic encephalitis
Disease
Source: DOID:4397
Definition: Not Available
Symbol: granulomatous dermatitis
Disease
Source: DOID:3089
Definition: Not Available
Symbol: granulomatous orchitis
Disease
Source: DOID:9113
Definition: A primary bacterial infectious disease that results_in infection located_in skin or located_in mucosa of genital tract, has_material_basis_in Klebsiella granulomatis, transmitted by sexual contact or transmitted_by contact with the open sores. The infection has_symptom painless genital ulcers.
Symbol: granuloma inguinale
Source: DOID:12132
Definition: An autoimmune disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.
Symbol: granulomatosis with polyangiitis
Gene Ontology
Source: GO:1901109
Synonyms:
- granaticin anabolism
- granaticin biosynthesis
Branch: biological process
Symbol: granaticin biosynthetic process
Gene Ontology
Source: GO:0036262
Synonyms: Not Available
Branch: biological process
Symbol: granulysin production
Gene Ontology
Source: GO:0051916
Synonyms:
- G-CSF binding
- granulocyte colony stimulating factor binding
Branch: molecular function
Symbol: granulocyte colony-stimulating factor binding
Gene Ontology
Source: GO:0060014
Synonyms: Not Available
Branch: biological process
Symbol: granulosa cell differentiation
Gene Ontology
Source: GO:0071613
Synonyms: Not Available
Branch: biological process
Symbol: granzyme B production
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by RGD
ID: GEO:GSE7697
Tags: unclassified
Summary: Keywords: Dose response
Symbol: Granulosa cell gene expression associated with oocyte developmental competence
Gene Ontology
Source: GO:0036230
Synonyms: Not Available
Branch: biological process
Symbol: granulocyte activation
Gene Ontology
Source: GO:1901107
Synonyms:
- granaticin metabolism
Branch: biological process
Symbol: granaticin metabolic process
Gene Ontology
Source: GO:0002432
Synonyms: Not Available
Branch: biological process
Symbol: granuloma formation
Gene Ontology
Source: GO:1990005
Synonyms: Not Available
Branch: cellular component
Symbol: granular vesicle
Gene Ontology
Source: GO:0009542
Synonyms: Not Available
Branch: cellular component
Symbol: granum
Gene Ontology
Source: GO:0009515
Synonyms:
- chloroplast stacked thylakoid
Branch: cellular component
Symbol: granal stacked thylakoid
Source: GO:0004901
Synonyms:
- CSF-2 receptor activity
- CSF2R
Branch: molecular function
Symbol: granulocyte macrophage colony-stimulating factor receptor activity
Gene Ontology
Source: GO:0071611
Synonyms:
- CSF3 production
- G-CSF production
Branch: biological process
Symbol: granulocyte colony-stimulating factor production
Source: GO:0005129
Synonyms:
- GM-CSF receptor binding
- GM-CSF receptor ligand
Branch: molecular function
Symbol: granulocyte macrophage colony-stimulating factor receptor binding