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652 results for grk1

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Grk1

(Rattus norvegicus)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: G protein-coupled receptpr kinase 1, Rhok, rhodopsin kinase, RK, rhodopsin kinase GRK1

Source: RGD:619712

Biotype: protein coding gene

Symbol: Grk1 (Rno)

Symbol: Grk1

Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1); PARTICIPATES IN visual phototransduction

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Synonyms: rhodopsin kinase GRK1

Strict Orthology Symbols: grk1

Alleles: Grk1 (Rno)

Grk1

(Mus musculus)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: Rhok, rhodopsin kinase, RK

Source: MGI:1345146

Biotype: protein coding gene

Symbol: Grk1 (Mmu)

Symbol: Grk1

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Strict Orthology Symbols: grk1

Alleles: Grk1 (Mmu)...Grk1 (Mmu)...Grk1 (Mmu)...Grk1 (Mmu)

GRK1

(Homo sapiens)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: GPRK1, RHOK, rhodopsin kinase, RK, rhodopsin kinase GRK1

Source: HGNC:10013

Biotype: protein coding gene

Symbol: GRK1 (Hsa)

Symbol: GRK1

Gene Synopsis: Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi

Synonyms: rhodopsin kinase GRK1

Strict Orthology Symbols: grk1

grk1

(Xenopus tropicalis)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: grk1, G protein-coupled receptor kinase 1

Source: Xenbase:XB-GENE-1012638

Biotype: gene

Symbol: grk1 (Xtr)

Symbol: grk1

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Synonyms: grk1...grk1...grk1

Strict Orthology Symbols: grk1a...GRK1...Grk1...grk1.L...grk1.S

Disease (5)

grk1a

(Danio rerio)

Gene

Name: G protein-coupled receptor kinase 1 a

Synonyms: Not Available

Source: ZFIN:ZDB-GENE-050823-1

Biotype: protein coding gene

Symbol: grk1a (Dre)

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Strict Orthology Symbols: grk1

Symbol: grk1a

grk1.L

(Xenopus laevis)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: grk1.L, G protein-coupled receptor kinase 1

Source: Xenbase:XB-GENE-17340986

Biotype: gene

Symbol: grk1.L (Xla)

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Strict Orthology Symbols: grk1

Symbol: grk1.L

Disease (2)

grk1.S

(Xenopus laevis)

Gene

Name: G protein-coupled receptor kinase 1

Synonyms: G protein-coupled receptor kinase 1, grk1.S

Source: Xenbase:XB-GENE-1012639

Biotype: gene

Symbol: grk1.S (Xla)

Automated Gene Synopsis: Orthologous to human GRK1 (G protein-coupled receptor kinase 1).

Strict Orthology Symbols: grk1

Symbol: grk1.S

Disease (2)

grk1b

(Danio rerio)

Gene

Name: G protein-coupled receptor kinase 1 b

Synonyms: zgc:112194

Source: ZFIN:ZDB-GENE-050417-211

Biotype: protein coding gene

Symbol: grk1b (Dre)

Symbol: grk1b

Grk1^tm1Citb

(Mus musculus)

Allele/Variant

Source: MGI:2668595

Genes: Grk1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Oguchi disease-2

Variant Name: Not Available

Symbol: Grk1 (Mmu)

Genes: Grk1 (Mmu)

Symbol: Grk1^tm1Citb

Grk1^em1Smoc

(Mus musculus)

Allele/Variant

Source: MGI:7290022

Genes: Grk1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Grk1 (Mmu)

Genes: Grk1 (Mmu)

Symbol: Grk1^em1Smoc

Gene (1)

Grk1^tm1.1Elrw

(Mus musculus)

Allele/Variant

Source: MGI:7550399

Genes: Grk1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Grk1 (Mmu)

Genes: Grk1 (Mmu)

Symbol: Grk1^tm1.1Elrw

Gene (1)

Grk1^tvrm207

(Mus musculus)

Allele/Variant

Source: MGI:5902745

Genes: Grk1 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Grk1 (Mmu)

Genes: Grk1 (Mmu)

Symbol: Grk1^tvrm207

Grk1^{Tn(sb-T2/Bart3)2.234Mcwi}

(Rattus norvegicus)

Allele/Variant

Source: RGD:2299115

Genes: Grk1 (Rno)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Grk1 (Rno)

Gene Synonyms: rhodopsin kinase GRK1

Genes: Grk1 (Rno)

Symbol: Grk1^{Tn(sb-T2/Bart3)2.234Mcwi}

Grk1^tvrm207/Grk1^tvrm207 [background:] B6.Cg-Grk1^tvrm207/Pjn

(Mus musculus)

Model

Id: MGI:5903251

Synonyms: Not Available

Symbol: Grk1/Grk1 [background:] B6.Cg-Grk1/Pjn (Mmu)

Genes: Grk1 (Mmu)

Alleles: Grk1 (Mmu)

Name: Grk1/Grk1 [background:] B6.Cg-Grk1/Pjn

Gene (1)

Grk1^tm1Citb/Grk1^tm1Citb Nrl^tm1Asw/Nrl^tm1Asw [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

(Mus musculus)

Model

Id: MGI:3041984

Synonyms: Not Available

Symbol: Grk1/Grk1 Nrl/Nrl [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL

Genes: Grk1 (Mmu)

Alleles: Grk1 (Mmu)

Name: Grk1/Grk1 Nrl/Nrl [background:] involves: 129S1/Sv * 129X1/SvJ * C57BL

Gene (2)

grk1b^nc201/nc201

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-190627-17

Synonyms: Not Available

Symbol: grk1b (Dre)

Genes: grk1b (Dre)

Gene (1)

Grk1^tm1Citb/Grk1^tm1Citb [background:] involves: 129X1/SvJ * C57BL/6

(Mus musculus)

Model

Id: MGI:2668598

Synonyms: Not Available

Symbol: Grk1/Grk1 [background:] involves: 129X1/SvJ * C57BL/6 (Mmu)

Genes: Grk1 (Mmu)

Alleles: Grk1 (Mmu)

Name: Grk1/Grk1 [background:] involves: 129X1/SvJ * C57BL/6

grk-1

(Caenorhabditis elegans)

Gene

Name: G-protein-coupled Receptor Kinase 1

Synonyms: F19C6.1, CELE_F19C6.1

Source: WB:WBGene00001708

Biotype: protein coding gene

Strict Orthology Symbols: grk1

Gprk2

(Drosophila melanogaster)

Gene

Name: G protein-coupled receptor kinase 2

Synonyms: Gprk-2, gprk2, Gprk 2, nosh, 154978_at, CG17998, GPRK2

Source: FB:FBgn0261988

Biotype: protein coding gene

Strict Orthology Symbols: grk1

Definition: A congenital stationary night blindness characterized by congenital static night blindness, a golden or gray-white discoloration of the fundus that disappears in the dark-adapted state and typically normal function of all other visual functions that has_material_basis_in homozygous mutation in the GRK1 gene on chromosome 13q34.

Genes: grk1 (Xtr)...grk1a (Dre)...Grk1 (Rno)...Grk1 (Mmu)...GRK1 (Hsa)

Alleles: Grk1 (Mmu)

retinal rod cell apoptotic process

Gene Ontology

Source: GO:0097473

Synonyms:

rod photoreceptor apoptotic process

Branch: biological process

Genes: Grk1 (Rno)...Grk1 (Mmu)...GRK1 (Hsa)

Genes Annotated with this GO Term (9)

rhodopsin kinase activity

Gene Ontology

Source: GO:0050254

Synonyms:

GPCR kinase 1 activity
cone opsin kinase activity

Branch: molecular function

Genes: grk1a (Dre)...Grk1 (Rno)...grk1b (Dre)...Grk1 (Mmu)...GRK1 (Hsa)

Genes Annotated with this GO Term (12)

regulation of opsin-mediated signaling pathway

Gene Ontology

Source: GO:0022400

Synonyms:

regulation of rhodopsin mediated signaling pathway
regulation of rhodopsin mediated signalling

Branch: biological process

Genes: GRK1 (Hsa)...grk1a (Dre)...Grk1 (Rno)...Grk1 (Mmu)

Genes Annotated with this GO Term (31)

post-embryonic retina morphogenesis in camera-type eye

Gene Ontology

Source: GO:0060060

Synonyms: Not Available

Branch: biological process

Genes: Grk1 (Rno)...Grk1 (Mmu)...GRK1 (Hsa)

Genes Annotated with this GO Term (9)

night blindness

Disease

Source: DOID:8499

Definition: A retinal disease that is characterized by difficulty or the inability to see in relatively low light.

Genes: grk1 (Xtr)...Grk1 (Mmu)...GRK1 (Hsa)...grk1a (Dre)...Grk1 (Rno)

F344-Grk1^{Tn(sb-T2/Bart3)2.234Mcwi}

(Rattus norvegicus)

Model

Id: RGD:2299131

Synonyms: F344-Grk1Tn(sb-T2/Bart3)2.234Mcwi

Genes: Grk1 (Rno)

Alleles: Grk1 (Rno)

Name: F344-<Grk1

Gene (1)

photoreceptor cell morphogenesis

Gene Ontology

Source: GO:0008594

Synonyms:

photoreceptor development

Branch: biological process

Genes: GRK1 (Hsa)...Grk1 (Rno)...Grk1 (Mmu)

Genes Annotated with this GO Term (43)

G protein-coupled receptor kinase activity

Gene Ontology

Source: GO:0004703

Synonyms:

ATP:G-protein-coupled receptor phosphotransferase activity
G protein coupled receptor phosphorylating protein kinase activity

Branch: molecular function

Genes: GRK1 (Hsa)...grk1a (Dre)...grk1b (Dre)

Genes Annotated with this GO Term (32)

WT + MO1-grk1b

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-220818-5

Synonyms: Not Available

Genes: grk1b (Dre)

Gene (1)

zko12a

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-171115-132

Genes: grk1a (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: grk1a (Dre)

Gene (1)

G protein-coupled opsin signaling pathway

Gene Ontology

Source: GO:0016056

Synonyms:

G protein-mediated opsin signaling pathway
rhodopsin mediated phototransduction

Branch: biological process

Genes: GRK1 (Hsa)...Grk1 (Rno)

Genes Annotated with this GO Term (26)

nc201

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-190509-6

Genes: grk1b (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: grk1b (Dre)

maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling

Gene Ontology

Source: GO:0016058

Synonyms:

maintenance of rhodopsin mediated signaling
maintenance of rhodopsin mediated signalling

Branch: biological process

Genes: GRK1 (Hsa)

Genes Annotated with this GO Term (1)

nc202

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-240222-5

Genes: grk1a (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: grk1a (Dre)

Gene (1)

regulation of membrane potential in photoreceptor cell

Gene Ontology

Source: GO:0016057

Synonyms:

changes in polarization state of photoreceptor cell membrane

Branch: biological process

Genes: GRK1 (Hsa)

Genes Annotated with this GO Term (8)

cone photoresponse recovery

Gene Ontology

Source: GO:0036368

Synonyms:

cone phototransduction termination
cone response recovery

Branch: biological process

Genes: grk1b (Dre)

Genes Annotated with this GO Term (9)

positive regulation of phosphorylation

Gene Ontology

Source: GO:0042327

Synonyms:

activation of phosphorylation
stimulation of phosphorylation

Branch: biological process

Genes: Grk1 (Mmu)...GRK1 (Hsa)...Grk1 (Rno)

Genes Annotated with this GO Term (1890)

retinal disease

Disease

Source: DOID:5679

Definition: An eye disease that is located_in the retina.

Genes: Grk1 (Mmu)...GRK1 (Hsa)...grk1a (Dre)...Grk1 (Rno)...grk1 (Xtr)

Tg(Grk1)1Shak

(Mus musculus)

Allele/Variant

Source: MGI:5567992

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Tg(Grk1)1Shak

Construct Expressed Component: Grk1 (Mmu)

Constructs: Tg(Grk1)1Shak construct

Tg(Rho-GRK1)1Cjch

(Mus musculus)

Allele/Variant

Source: MGI:6160441

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Tg(Rho-GRK1)1Cjch

Construct Expressed Component: GRK1

Model (1)

photoreceptor disc membrane

Gene Ontology

Source: GO:0097381

Synonyms: Not Available

Branch: cellular component

Genes: GRK1 (Hsa)

Genes Annotated with this GO Term (34)

response to light stimulus

Gene Ontology

Source: GO:0009416

Synonyms: Not Available

Branch: biological process

Genes: Grk1 (Mmu)...GRK1 (Hsa)...Grk1 (Rno)

Genes Annotated with this GO Term (1440)

Tg(Rho-GRK1)1Cjch/? [background:] involves: C57BL/6 * SJL

(Mus musculus)

Model

Id: MGI:6160443

Synonyms: Not Available

Name: Tg(Rho-GRK1)1Cjch/? [background:] involves: C57BL/6 * SJL

regulation of signal transduction

Gene Ontology

Source: GO:0009966

Synonyms:

regulation of signaling pathway
regulation of signalling pathway

Branch: biological process

Genes: Grk1 (Mmu)...grk1b (Dre)...GRK1 (Hsa)...grk1a (Dre)...Grk1 (Rno)

Genes Annotated with this GO Term (10000)

G protein-coupled photoreceptor activity

Gene Ontology

Source: GO:0008020

Synonyms:

G protein coupled photoreceptor activity
G-protein coupled photoreceptor activity

Branch: molecular function

Genes: GRK1 (Hsa)

Genes Annotated with this GO Term (90)

photoreceptor outer segment

Gene Ontology

Source: GO:0001750

Synonyms: Not Available

Branch: cellular component

Genes: Grk1 (Mmu)...GRK1 (Hsa)...Grk1 (Rno)

Genes Annotated with this GO Term (357)

grk::yl^{grk1-275.yl1826-1984}

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0193435

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: grk::yl<grk1-275.yl1826-1984>

visual perception

Gene Ontology

Source: GO:0007601

Synonyms:

sense of sight
sensory visual perception

Branch: biological process

Genes: Grk1 (Mmu)...Grk1 (Rno)...GRK1 (Hsa)...grk1a (Dre)

Genes Annotated with this GO Term (725)

protein autophosphorylation

Gene Ontology

Source: GO:0046777

Synonyms:

protein amino acid autophosphorylation

Branch: biological process

Genes: Grk1 (Mmu)...Grk1 (Rno)...GRK1 (Hsa)

Genes Annotated with this GO Term (561)

phosphorylation

Gene Ontology

Source: GO:0016310

Synonyms: Not Available

Branch: biological process

Genes: grk1a (Dre)...Grk1 (Mmu)...grk1b (Dre)...Grk1 (Rno)...GRK1 (Hsa)

Genes Annotated with this GO Term (3423)

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