[object Object]

Category

4,110 results for hdac8

Page 1 of 83

HDAC8

(Homo sapiens)

Gene

Name: histone deacetylase 8

Synonyms: MRXS6, WTS, CDA07, HDACL1, histone deacetylase-like 1, RPD3, Wilson-Turner X-linked mental retardation syndrome, HD8, CDLS5, KDAC8, Wilson-Turner syndrome (mental retardation, X-linked, syndromic-6, with gynecomastia and obesity)

Source: HGNC:13315

Biotype: protein coding gene

Symbol: HDAC8 (Hsa)

Symbol: HDAC8

Strict Orthology Symbols: hdac8

Hdac8

(Rattus norvegicus)

Gene

Name: histone deacetylase 8

Synonyms: similar to Histone deacetylase 8 (HD8), uncharacterized LOC103690124, RGD1562895, LOC363481, LOC103690124, HD8

Source: RGD:1562895

Biotype: protein coding gene

Symbol: Hdac8 (Rno)

Symbol: Hdac8

Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8); PARTICIPATES IN histone modification pathway; INTERACTS

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Strict Orthology Symbols: hdac8

Hdac8

(Mus musculus)

Gene

Name: histone deacetylase 8

Synonyms: RIKEN cDNA 2610007D20 gene, RGD1562895, 2610007D20Rik, HD8

Source: MGI:1917565

Biotype: protein coding gene

Symbol: Hdac8 (Mmu)

Symbol: Hdac8

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Strict Orthology Symbols: hdac8

Alleles: Hdac8 (Mmu)...Hdac8 (Mmu)...Hdac8 (Mmu)...Hdac8 (Mmu)...Hdac8 (Mmu)

hdac8

(Danio rerio)

Gene

Name: histone deacetylase 8

Synonyms: zgc:66196, wu:fd19a02

Source: ZFIN:ZDB-GENE-040426-2772

Biotype: protein coding gene

Symbol: hdac8 (Dre)

Symbol: hdac8

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Strict Orthology Symbols: hdac8

hdac8

(Xenopus tropicalis)

Gene

Name: histone deacetylase 8

Synonyms: hdac8, histone deacetylase 8

Source: Xenbase:XB-GENE-5863426

Biotype: gene

Symbol: hdac8

Symbol: hdac8 (Xtr)

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Synonyms: hdac8...hdac8...hdac8

Strict Orthology Symbols: hdac8

Disease (8)

hdac8.L

(Xenopus laevis)

Gene

Name: histone deacetylase 8

Synonyms: histone deacetylase 8, hdac8.L

Source: Xenbase:XB-GENE-5863488

Biotype: gene

Symbol: hdac8.L (Xla)

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Strict Orthology Symbols: hdac8

Symbol: hdac8.L

Disease (4)

Hdac8^em1Lutzy

(Mus musculus)

Allele/Variant

Source: MGI:7783542

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^em1Lutzy

Gene (1)

Hdac8^em1Gpt

(Mus musculus)

Allele/Variant

Source: MGI:7300184

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^em1Gpt

Gene (1)

Hdac8^tm1.1Mrl

(Mus musculus)

Allele/Variant

Source: MGI:6433082

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^tm1.1Mrl

Gene (1)

Hdac8^tm1.1Eno

(Mus musculus)

Allele/Variant

Source: MGI:3851814

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^tm1.1Eno

Hdac8^{tm1c(EUCOMM)Wtsi}

(Mus musculus)

Allele/Variant

Source: MGI:7408099

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^{tm1c(EUCOMM)Wtsi}

Gene (1)

Hdac8^{tm1a(EUCOMM)Wtsi}

(Mus musculus)

Allele/Variant

Source: MGI:4432268

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^{tm1a(EUCOMM)Wtsi}

Hdac8^{tm1d(EUCOMM)Wtsi}

(Mus musculus)

Allele/Variant

Source: MGI:7408100

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^{tm1d(EUCOMM)Wtsi}

Gene (1)

Hdac8^tm1.2Eno

(Mus musculus)

Allele/Variant

Source: MGI:3851815

Genes: Hdac8 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Cornelia de Lange syndrome 5

Variant Name: Not Available

Symbol: Hdac8 (Mmu)

Genes: Hdac8 (Mmu)

Symbol: Hdac8^tm1.2Eno

Hdac8^{tm1a(EUCOMM)Wtsi}/Hdac8^{tm1a(EUCOMM)Wtsi} [background:] C57BL/6N-Hdac8^{tm1a(EUCOMM)Wtsi}/Wtsi

(Mus musculus)

Model

Id: MGI:5781638

Synonyms: Not Available

Symbol: Hdac8/Hdac8 [background:] C57BL/6N-Hdac8/Wtsi

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8 [background:] C57BL/6N-Hdac8/Wtsi

Gene (1)

Hdac8^tm1.1Eno/Y Tg(Col1a1-cre)1Kry/0 [background:] involves: 129 * C57BL/6 * CD-1 * FVB/N

(Mus musculus)

Model

Id: MGI:3851915

Synonyms: Not Available

Symbol: Hdac8/Y Tg(Col1a1-cre)1Kry/0 [background:] involves: 129 * C57BL/6 * CD-1 * FVB/N (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y Tg(Col1a1-cre)1Kry/0 [background:] involves: 129 * C57BL/6 * CD-1 * FVB/N

Gene (1)

Hdac8^tm1.2Eno/Hdac8⁺ [background:] involves: 129 * C57BL/6 * CD-1

(Mus musculus)

Model

Id: MGI:3851912

Synonyms: Not Available

Symbol: Hdac8/Hdac8<+> [background:] involves: 129 * C57BL/6 * CD-1 (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8<+> [background:] involves: 129 * C57BL/6 * CD-1

Gene (1)

Hdac8^tm1.1Eno/Y Twist2^tm1(cre)Dor/Twist2⁺ [background:] involves: 129 * C57BL/6 * CD-1 * SJL

(Mus musculus)

Model

Id: MGI:3851917

Synonyms: Not Available

Symbol: Hdac8/Y Twist2/Twist2<+> [background:] involves: 129 * C57BL/6 * CD-1 * SJL (

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y Twist2/Twist2<+> [background:] involves: 129 * C57BL/6 * CD-1 * SJL

Gene (2)

Hdac8^tm1.2Eno/Y [background:] involves: 129S6/SvEvTac * C57BL/6J

(Mus musculus)

Model

Id: MGI:7491951

Synonyms: Not Available

Symbol: Hdac8/Y [background:] involves: 129S6/SvEvTac * C57BL/6J (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y [background:] involves: 129S6/SvEvTac * C57BL/6J

Hdac8^tm1.1Eno/Hdac8^tm1.2Eno Tg(Ddx4-cre)1Dcas/0 [background:] involves: 129S6/SvEvTac * C57BL/6J * FVB

(Mus musculus)

Model

Id: MGI:6835645

Synonyms: Not Available

Symbol: Hdac8/Hdac8 Tg(Ddx4-cre)1Dcas/0 [background:] involves: 129S6/SvEvTac * C57BL/6J

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8 Tg(Ddx4-cre)1Dcas/0 [background:] involves: 129S6/SvEvTac * C57BL/6J

Gene (1)

Hdac8^{tm1a(EUCOMM)Wtsi}/Y [background:] C57BL/6N-Hdac8^{tm1a(EUCOMM)Wtsi}/Wtsi

(Mus musculus)

Model

Id: MGI:5781637

Synonyms: Not Available

Symbol: Hdac8/Y [background:] C57BL/6N-Hdac8/Wtsi (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y [background:] C57BL/6N-Hdac8/Wtsi

Gene (1)

Hdac8^tm1.1Eno/Hdac8^tm1.1Eno Tg(Zp3-cre)93Knw/0 [background:] involves: 129S6/SvEvTac * C57BL/6J

(Mus musculus)

Model

Id: MGI:6835643

Synonyms: Not Available

Symbol: Hdac8/Hdac8 Tg(Zp3-cre)93Knw/0 [background:] involves: 129S6/SvEvTac * C57BL/6J

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8 Tg(Zp3-cre)93Knw/0 [background:] involves: 129S6/SvEvTac * C57BL/6J

Gene (1)

Hdac8^tm1.1Eno/Y Tg(Col2a1-cre)1Bhr/0 [background:] involves: 129 * C57BL/6 * CD-1 * SJL

(Mus musculus)

Model

Id: MGI:3851916

Synonyms: Not Available

Symbol: Hdac8/Y Tg(Col2a1-cre)1Bhr/0 [background:] involves: 129 * C57BL/6 * CD-1 * SJL (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y Tg(Col2a1-cre)1Bhr/0 [background:] involves: 129 * C57BL/6 * CD-1 * SJL

Gene (1)

Hdac8^tm1.2Eno/Hdac8^tm1.2Eno [background:] involves: 129 * C57BL/6 * CD-1

(Mus musculus)

Model

Id: MGI:3851911

Synonyms: Not Available

Symbol: Hdac8/Hdac8 [background:] involves: 129 * C57BL/6 * CD-1 (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8 [background:] involves: 129 * C57BL/6 * CD-1

Gene (1)

Hdac8^tm1.1Eno/Y H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ [background:] involves: 129 * C57BL/6 * CBA * CD-1

(Mus musculus)

Model

Id: MGI:3851920

Synonyms: Not Available

Symbol: Hdac8/Y H2az2/H2az2<+> [background:] involves: 129 * C57BL/6 * CBA * CD

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y H2az2/H2az2<+> [background:] involves: 129 * C57BL/6 * CBA * CD

Gene (2)

Hdac8^tm1.2Eno/Hdac8⁺ Tg(CAG-Hdac8,-EGFP)1Eno/0 [background:] involves: 129 * C57BL/6 * C3H * CD-1

(Mus musculus)

Model

Id: MGI:3851913

Synonyms: Not Available

Symbol: Hdac8/Hdac8<+> Tg(CAG-Hdac8,-EGFP)1Eno/0 [background:] involves: 129 * C57BL/6 * C3H * CD-

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Hdac8<+> Tg(CAG-Hdac8,-EGFP)1Eno/0 [background:] involves: 129 * C57BL/6 * C3H * CD-

Gene (1)

Hdac8^tm1.2Eno/Y [background:] involves: 129 * C57BL/6 * CD-1

(Mus musculus)

Model

Id: MGI:3851910

Synonyms: Not Available

Symbol: Hdac8/Y [background:] involves: 129 * C57BL/6 * CD-1 (Mmu)

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Hdac8/Y [background:] involves: 129 * C57BL/6 * CD-1

Gene (1)

HOS1

(Saccharomyces cerevisiae)

Gene

Name: Hda One Similar

Synonyms: CST3, YPR068C

Source: SGD:S000006272

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human HDAC8 (histone deacetylase 8).

Strict Orthology Symbols: hdac8

Cornelia de Lange syndrome 5

Disease

Source: DOID:0080509

Definition: A Cornelia de Lange syndrome that has_material_basis_in by mutation in the HDAC8 gene on chromosome Xq13.

Genes: hdac8.L (Xla)...Hdac8 (Mmu)...hdac8 (Dre)...HDAC8 (Hsa)...hdac8 (Xtr)

Alleles: Hdac8 (Mmu)

Wilson-Turner syndrome

Disease

Source: DOID:0060814

Definition: A syndromic X-linked intellectual disability characterized by intellectual disability, truncal obesity, gynecomastia, hypogonadism, dysmorphic facial features, and short stature that has_material_basis_in hemizygous mutation in the LAS1L gene on chromosome Xq12.

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...hdac8 (Xtr)...Hdac8 (Rno)...hdac8 (Dre)

Gene (17)

histone decrotonylase activity

Gene Ontology

Source: GO:0160009

Synonyms: Not Available

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)...hdac8 (Dre)

Genes Annotated with this GO Term (17)

tubulin deacetylase activity

Gene Ontology

Source: GO:0042903

Synonyms: Not Available

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...hdac8 (Dre)...Hdac8 (Rno)

Genes Annotated with this GO Term (25)

negative regulation of protein modification process

Gene Ontology

Source: GO:0031400

Synonyms:

down regulation of protein modification
down-regulation of protein modification

Branch: biological process

Genes: Hdac8 (Mmu)...Hdac8 (Rno)

Genes Annotated with this GO Term (1310)

Cornelia de Lange syndrome

Disease

Source: DOID:11725

Definition: A syndrome that is characterized by slow growth before and after birth, intellectual disability that is usually severe to profound, skeletal abnormalities involving the arms and hands, and distinctive facial features.

Genes: Hdac8 (Mmu)...hdac8 (Xtr)...hdac8 (Dre)...HDAC8 (Hsa)...Hdac8 (Rno)

histone H3K4 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:1990162

Synonyms:

histone H3-K4 deacetylase activity
histone H3K14 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...hdac8 (Dre)...Hdac8 (Rno)

Genes Annotated with this GO Term (43)

histone H4K8 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0180033

Synonyms:

histone H4K48 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)

Genes Annotated with this GO Term (33)

Eif2ak2^tm1Cwe/Eif2ak2^tm1Cwe Hdac8^tm1.2Eno/Y [background:] involves: 129/Sv * 129S6/SvEvTac * C57BL/6J

(Mus musculus)

Model

Id: MGI:7491953

Synonyms: Not Available

Genes: Hdac8 (Mmu)

Alleles: Hdac8 (Mmu)

Name: Eif2ak2/Eif2ak2 Hdac8/Y [background:] involves: 129/Sv * 129S6/SvEvTac * C57BL

Symbol: Eif2ak2/Eif2ak2 Hdac8/Y [background:] involves: 129/Sv * 129S6/SvEvTac * C57BL

Gene (2)

cellular response to trichostatin A

Gene Ontology

Source: GO:0035984

Synonyms: Not Available

Branch: biological process

Genes: Hdac8 (Mmu)...Hdac8 (Rno)

Genes Annotated with this GO Term (17)

histone H4K5 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0180032

Synonyms:

histone H4K5 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)

Genes Annotated with this GO Term (33)

response to 11-deoxycorticosterone

Gene Ontology

Source: GO:1903496

Synonyms: Not Available

Branch: biological process

Genes: Hdac8 (Mmu)...Hdac8 (Rno)

Genes Annotated with this GO Term (5)

AB + MO2-hdac8

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-200630-1

Synonyms: Not Available

Genes: hdac8 (Dre)

Name: AB + MO2-hdac8

histone H4K12 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0140937

Synonyms:

histone H4-K12 deacetylase activity
histone H4-K12 deacetylation

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...hdac8 (Dre)...Hdac8 (Rno)

Genes Annotated with this GO Term (46)

histone H4K16 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0034739

Synonyms:

histone H4-K16 deacetylase activity
histone H4K12 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)

Genes Annotated with this GO Term (34)

histone H3K14 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0031078

Synonyms:

histone H3-K14 deacetylase activity
histone H3K14 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)

Genes Annotated with this GO Term (34)

sa44675

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-190123-321

Genes: hdac8 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: hdac8 (Dre)

Gene (1)

histone H3K9 deacetylase activity, hydrolytic mechanism

Gene Ontology

Source: GO:0032129

Synonyms:

histone H3-K9 deacetylase activity
histone H3K9 deacetylase activity

Branch: molecular function

Genes: Hdac8 (Mmu)...HDAC8 (Hsa)...Hdac8 (Rno)

Genes Annotated with this GO Term (36)

WT + MO1-hdac8 + MO1-tp53

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-240516-9

Synonyms: Not Available

Genes: hdac8 (Dre)

Name: WT + MO1-hdac8 + MO1-tp53

Gene (2)

mtm1^zf711/zf711 + MO1-hdac8 + MO1-tp53

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-240516-14

Synonyms: Not Available

Genes: hdac8 (Dre)

Name: mtm1 + MO1-hdac8 + MO1-tp53

Gene (3)

la026136Tg

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-120806-9534

Genes: hdac8 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: hdac8 (Dre)

Gene (1)

li1Tg; uf1Tg + MO1-hdac8

(Danio rerio)

Model

Id: ZFIN:ZDB-FISH-230327-13

Synonyms: Not Available

Genes: hdac8 (Dre)

Name: li1Tg; uf1Tg + MO1-hdac8

Gene (1)

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