Version: 8.0.0Date: Tue Jan 28 2025
Category
Hpse2
(Rattus norvegicus)Gene
Name: heparanase 2 (inactive)
Synonyms: LOC293955, similar to Heparanase-2 (Hpa2), inactive heparanase-2, uncharacterized LOC108349826, LOC368128, LOC108349826, heparanase 2, heparanase-2
Source: RGD:1307959
Biotype: protein coding gene
Symbol: Hpse2 (Rno)
Symbol: Hpse2
Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)); PARTICIPATES IN glycosaminoglycan degradation pathway
Automated Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)).
Strict Orthology Symbols: HPSE2
hpse2
(Danio rerio)Gene
Name: heparanase 2
Synonyms: si:dkeyp-22h2.2
Source: ZFIN:ZDB-GENE-090313-378
Biotype: protein coding gene
Symbol: hpse2 (Dre)
Symbol: hpse2
Automated Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)).
Strict Orthology Symbols: hpse2
Hpse2
(Mus musculus)Gene
Name: heparanase 2
Synonyms: gene model 968, (NCBI), Gm968
Source: MGI:2685814
Biotype: protein coding gene
Symbol: Hpse2 (Mmu)
Symbol: Hpse2
Automated Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)).
Strict Orthology Symbols: hpse2
Alleles: Hpse2
HPSE2
(Homo sapiens)Gene
Name: heparanase 2 (inactive)
Synonyms: UFS, MGC133234, UFS1, HPR2, FLJ44022, heparanase 3, heparanase-like protein, FLJ11684, Ochoa syndrome, inactive heparanase-2, urofacial syndrome, HPA2, heparanase-2
Source: HGNC:18374
Biotype: protein coding gene
Symbol: HPSE2 (Hsa)
Symbol: HPSE2
Strict Orthology Symbols: hpse2
hpse2
(Xenopus tropicalis)Gene
Name: heparanase 2 (inactive)
Synonyms: heparanase 2 (inactive), hpse2
Source: Xenbase:XB-GENE-989584
Biotype: gene
Symbol: hpse2
Symbol: hpse2 (Xtr)
Automated Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)).
Synonyms: hpse2...hpse2...hpse2
Strict Orthology Symbols: hpse2
hpse2.L
(Xenopus laevis)Gene
Name: heparanase 2 (inactive)
Synonyms: heparanase 2 (inactive), hpse2.L
Source: Xenbase:XB-GENE-17335191
Biotype: gene
Symbol: hpse2.L (Xla)
Automated Gene Synopsis: Orthologous to human HPSE2 (heparanase 2 (inactive)).
Strict Orthology Symbols: hpse2
Symbol: hpse2.L
Hpse2em1(IMPC)J
(Mus musculus)Allele/Variant
Source: MGI:5749801
Genes: Hpse2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hpse2
Genes: Hpse2 (Mmu)
Symbol: Hpse2em1(IMPC)J
Hpse2Gt(OST441123)Lex
(Mus musculus)Allele/Variant
Source: MGI:4318356
Genes: Hpse2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hpse2
Genes: Hpse2 (Mmu)
Symbol: Hpse2Gt(OST441123)Lex
Hpse2Gt(OST411605)Lex
(Mus musculus)Allele/Variant
Source: MGI:4308701
Genes: Hpse2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: urofacial syndrome
Variant Name: Not Available
Symbol: Hpse2
Genes: Hpse2 (Mmu)
Symbol: Hpse2Gt(OST411605)Lex
Hpse2em13Gpt
(Mus musculus)Allele/Variant
Source: MGI:7300387
Genes: Hpse2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hpse2
Genes: Hpse2 (Mmu)
Symbol: Hpse2em13Gpt
Hpse2em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7300388
Genes: Hpse2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hpse2
Genes: Hpse2 (Mmu)
Symbol: Hpse2em1Gpt
Model
Id: MGI:6262648
Synonyms: Not Available
Symbol: Hpse2/Hpse2 [background:] C57BL/6NJ-Hpse2/J (Mmu)
Genes: Hpse2 (Mmu)
Alleles: Hpse2
Name: Hpse2/Hpse2 [background:] C57BL/6NJ-Hpse2/J
Hpse2Gt(OST411605)Lex/Hpse2Gt(OST411605)Lex [background:] involves: 129S5/SvEvBrd * C57BL/6
(Mus musculus)Model
Id: MGI:5694081
Synonyms: Not Available
Symbol: Hpse2/Hpse2 [background:] involves: 129S5/SvEvBrd * C57BL/6 (Mmu
Genes: Hpse2 (Mmu)
Alleles: Hpse2
Name: Hpse2/Hpse2 [background:] involves: 129S5/SvEvBrd * C57BL/6
Model
Id: MGI:6262647
Synonyms: Not Available
Symbol: Hpse2/Hpse2<+> [background:] C57BL/6NJ-Hpse2/J (Mmu)
Genes: Hpse2 (Mmu)
Alleles: Hpse2
Name: Hpse2/Hpse2<+> [background:] C57BL/6NJ-Hpse2/J
CG14309
(Drosophila melanogaster)Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0038611
Biotype: protein coding gene
Strict Orthology Symbols: hpse2
Hpse
(Rattus norvegicus)Gene
Name: heparanase
Synonyms: Hep, LOC100362546, endo-glucoronidase, Hpa, heparanase-like
Source: RGD:61969
Biotype: protein coding gene
Strict Orthology Symbols: hpse2
Disease
Source: DOID:0050816
Definition: A syndrome that is characterized by inverted facial expressions in association with a severe and early-onset form of dysfunctional urinary voiding.
Genes: Hpse2 (Rno)...Hpse2 (Mmu)...hpse2 (Dre)...HPSE2 (Hsa)...hpse2 (Xtr)
Alleles: Hpse2
Gene Ontology
Source: GO:0030305
Synonyms:
- heparinase activity
Branch: molecular function
Genes: Hpse2 (Rno)...HPSE2 (Hsa)
la018623Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-120806-11773
Genes: hpse2 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: hpse2 (Dre)
Gene Ontology
Source: GO:0043395
Synonyms:
- heparin proteoglycan binding
Branch: molecular function
Genes: Hpse2 (Rno)...Hpse2 (Mmu)...HPSE2 (Hsa)
Gene Ontology
Source: GO:0016798
Synonyms:
- N-glycosylase
- glycosidase activity
Branch: molecular function
Genes: hpse2 (Dre)...Hpse2 (Mmu)...HPSE2 (Hsa)
Gene Ontology
Source: GO:0030198
Synonyms:
- extracellular matrix organisation
- extracellular matrix organization and biogenesis
Branch: biological process
Genes: Hpse2 (Rno)...hpse2 (Dre)...Hpse2 (Mmu)...HPSE2 (Hsa)
Gene Ontology
Source: GO:0031012
Synonyms:
- matrisome
- proteinaceous extracellular matrix
Branch: cellular component
Genes: hpse2 (Dre)...HPSE2 (Hsa)...Hpse2 (Rno)...Hpse2 (Mmu)
Gene Ontology
Source: GO:0008283
Synonyms:
- cell proliferation
Branch: biological process
Genes: HPSE2 (Hsa)...Hpse2 (Rno)...Hpse2 (Mmu)
Gene Ontology
Source: GO:0008284
Synonyms:
- activation of cell proliferation
- positive regulation of cell proliferation
Branch: biological process
Genes: Hpse2 (Mmu)...HPSE2 (Hsa)...Hpse2 (Rno)
Gene Ontology
Source: GO:0005615
Synonyms:
- intercellular space
Branch: cellular component
Genes: hpse2 (Dre)...HPSE2 (Hsa)...Hpse2 (Mmu)...Hpse2 (Rno)
Gene Ontology
Source: GO:0005576
Synonyms:
- extracellular
Branch: cellular component
Genes: HPSE2 (Hsa)...Hpse2 (Mmu)
Gene Ontology
Source: GO:0016020
Synonyms:
- integral component of membrane
- integral to membrane
Branch: cellular component
Genes: hpse2 (Dre)...Hpse2 (Rno)...HPSE2 (Hsa)...Hpse2 (Mmu)
Gene Ontology
Source: GO:0005886
Synonyms:
- bacterial inner membrane
- cell membrane
Branch: cellular component
Genes: HPSE2 (Hsa)
(GRCh38)10:99235718A>C
(Homo sapiens)Allele/Variant
Source: rs1035371322
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:99235718A>C
(GRCh38)10:98744179T>G
(Homo sapiens)Allele/Variant
Source: rs7074540
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98744179T>G
(GRCh38)10:98641658T>C
(Homo sapiens)Allele/Variant
Source: rs115702469
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98641658T>C
(GRCh38)10:98721690C>T
(Homo sapiens)Allele/Variant
Source: rs761701445
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98721690C>T
(GRCh38)10:98459617T>A
(Homo sapiens)Allele/Variant
Source: rs10883100
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98459617T>A
(GRCh38)10:99235543A>G
(Homo sapiens)Allele/Variant
Source: rs140162468
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:99235543A>G
(GRCh38)10:99030395G>A
(Homo sapiens)Allele/Variant
Source: rs207471303
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:99030395G>A
(GRCh38)10:98459585G>T
(Homo sapiens)Allele/Variant
Source: rs745695570
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98459585G>T
(GRCh38)10:98459689A>C
(Homo sapiens)Allele/Variant
Source: NC_000010.11:g.98459689A>C
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98459689A>C
(GRCh38)10:98459739C>A
(Homo sapiens)Allele/Variant
Source: rs1237549253
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98459739C>A
(GRCh38)10:98693916C>T
(Homo sapiens)Allele/Variant
Source: rs749742654
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98693916C>T
(GRCh38)10:98721707A>G
(Homo sapiens)Allele/Variant
Source: rs890725875
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98721707A>G
(GRCh38)10:98721736T>A
(Homo sapiens)Allele/Variant
Source: rs758852189
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98721736T>A
(GRCh38)10:98721767A>G
(Homo sapiens)Allele/Variant
Source: rs779841448
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98721767A>G
(GRCh38)10:98459762G>A
(Homo sapiens)Allele/Variant
Source: rs11189618
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98459762G>A
(GRCh38)10:98693950G>A
(Homo sapiens)Allele/Variant
Source: NC_000010.11:g.98693950G>A
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98693950G>A
(GRCh38)10:98620625G>A
(Homo sapiens)Allele/Variant
Source: rs372169556
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98620625G>A
(GRCh38)10:98620636T>C
(Homo sapiens)Allele/Variant
Source: rs777003298
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98620636T>C
(GRCh38)10:99232748G>A
(Homo sapiens)Allele/Variant
Source: rs3814144
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:99232748G>A
(GRCh38)10:99235673T>C
(Homo sapiens)Allele/Variant
Source: rs777269780
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:99235673T>C
(GRCh38)10:98743957T>C
(Homo sapiens)Allele/Variant
Source: rs1418363244
Genes: HPSE2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)10:98743957T>C