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321 results for hsd17b10

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HSD17B10

(Homo sapiens)

Gene

Name: hydroxysteroid 17-beta dehydrogenase 10

Synonyms: HADH2, endoplasmic reticulum-associated amyloid beta-peptide-binding protein, 3-hydroxyacyl-CoA dehydrogenase type-2, hydroxysteroid dehydrogenase 10, SDR5C1, short chain dehydrogenase/reductase family 5C, member 1, HCD2, short chain dehydrogenase/reductase family 5C member 1, MRPP2, short chain type dehydrogenase/reductase XH98G2, short chain L-3-hydroxyacyl-CoA dehydrogenase type 2, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, DUPXp11.22, MRX31, MRX17, ABAD, amyloid-beta peptide binding alcohol dehydrogenase, CAMR, AB-binding alcohol dehydrogenase, 17b-HSD10, mitochondrial ribonuclease P protein 2, SCHAD, ERAB, MRXS10, hydroxysteroid (17-beta) dehydrogenase 10, mitochondrial RNase P subunit 2, HSD10MD, mental retardation, X-linked 31, MHBD, mental retardation, X-linked, syndromic 10, mental retardation, X-linked 17

Source: HGNC:4800

Biotype: protein coding gene

Symbol: HSD17B10 (Hsa)

Symbol: HSD17B10

Strict Orthology Symbols: hsd17b10

hsd17b10

(Danio rerio)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: wu:fj61f03, zgc:101605, hadh2, hydroxyacyl-coenzyme A dehydrogenase type II, im:6899159

Source: ZFIN:ZDB-GENE-041010-201

Biotype: protein coding gene

Symbol: hsd17b10 (Dre)

Symbol: hsd17b10

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

Hsd17b10

(Mus musculus)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: Hadh2, HSD10, Ads9, MHBD, ABAD, ERAB, hydroxyacyl-Coenzyme A dehydrogenase type II

Source: MGI:1333871

Biotype: protein coding gene

Symbol: Hsd17b10 (Mmu)

Symbol: Hsd17b10

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

Hsd17b10

(Rattus norvegicus)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: mitochondrial RNase P protein 2, endoplasmic reticulum-associated amyloid beta-peptide-binding protein, 3-hydroxyacyl-CoA dehydrogenase type-2, hydroxyacyl-Coenzyme A dehydrogenase, type II, short chain dehydrogenase/reductase family 5C member 1, 17-beta-estradiol 17-dehydrogenase, Hadh2, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, amyloid beta-peptide binding protein, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, short-chain type dehydrogenase/reductase XH98G2, ABAD, amyloid-beta peptide binding alcohol dehydrogenase, short chain L-3-hydroxyacyl-CoA dehydrogenase, mitochondrial ribonuclease P protein 2, HSD10, 17-beta-HSD 10, 7-alpha-hydroxysteroid dehydrogenase, 17-beta-hydroxysteroid dehydrogenase 10, type II HADH, ERAB, 17I(2)-hydroxysteroid dehydrogenase type 10, 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)), MHBD, 3-hydroxyacyl-CoA dehydrogenase type II, 3alpha(or 20beta)-hydroxysteroid dehydrogenase, hydroxyacyl-Coenzyme A dehydrogenase type II

Source: RGD:69231

Biotype: protein coding gene

Symbol: Hsd17b10 (Rno)

Symbol: Hsd17b10

Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10); PARTICIPATES IN 3-hydroxy-3-

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

hsd17b10

(Xenopus tropicalis)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: erab, mrxs10, mrx31, abad, mrx17, camr, mhbd, hydroxysteroid (17-beta) dehydrogenase 10, sdr5c1, hadh2, hsd10, schad, mrpp2, hcd2, hsd17b10

Source: Xenbase:XB-GENE-986902

Biotype: gene

Symbol: hsd17b10

Symbol: hsd17b10 (Xtr)

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Synonyms: hsd17b10...hsd17b10...hsd17b10

Strict Orthology Symbols: hsd17b10

Disease (4)

hsd17b10.L

(Xenopus laevis)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: erab, mrxs10, mrx31, abad, mrx17, camr, mhbd, hydroxysteroid (17-beta) dehydrogenase 10, sdr5c1, hsd17b10.L, hadh2, hsd10, mrpp2, schad, hcd2

Source: Xenbase:XB-GENE-986908

Biotype: gene

Symbol: hsd17b10.L (Xla)

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

Symbol: hsd17b10.L

Disease (4)

hsd17b10.S

(Xenopus laevis)

Gene

Name: hydroxysteroid (17-beta) dehydrogenase 10

Synonyms: erab, mrxs10, mrx31, abad, mrx17, camr, mhbd, hydroxysteroid (17-beta) dehydrogenase 10, sdr5c1, hadh2, hsd17b10.S, hsd10, schad, mrpp2, hcd2

Source: Xenbase:XB-GENE-17343939

Biotype: gene

Symbol: hsd17b10.S (Xla)

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

Symbol: hsd17b10.S

Disease (4)

ard-1

(Caenorhabditis elegans)

Gene

Name: Alcohol/Ribitol Dehydrogenase family 1

Synonyms: CELE_F01G4.2, F01G4.2

Source: WB:WBGene00000181

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Strict Orthology Symbols: hsd17b10

scu

(Drosophila melanogaster)

Gene

Name: scully

Synonyms: lethal(1)17Ad, Scu, 3-hydroxyacyl-CoA dehydrogenase, HLII, haplo-lethal region II, 17beta-HSD10, HSD17B10, HL-X, MRPP2, scully, l(1)17Ad, CG7113, Scully, l(1)16Fd, 17-beta-hydroxysteroid dehydrogenase 10 ortholog

Source: FB:FBgn0021765

Biotype: protein coding gene

Automated Gene Synopsis: Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).

Synonyms: HSD17B10...HSD17B10

Strict Orthology Symbols: hsd17b10

ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

Gene Ontology

Source: GO:0106283

Synonyms: Not Available

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (3)

brexanolone metabolic process

Gene Ontology

Source: GO:0062173

Synonyms:

allopregnanolone metabolic process
allopregnanolone metabolism

Branch: biological process

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (6)

syndromic X-linked intellectual disability type 10

Disease

Source: DOID:0060810

Definition: A syndromic X-linked intellectual disability characterized by mild intellectual deficit associated with choreoathetosis and abnormal behaviour that has_material_basis_in mutation in the HSD17B10 gene on chromosome Xp11.22.

Genes: hsd17b10 (Dre)...Hsd17b10 (Mmu)...hsd17b10 (Xtr)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

cholate 7-alpha-dehydrogenase activity

Gene Ontology

Source: GO:0008709

Synonyms:

7-alpha-hydroxysteroid dehydrogenase activity
7alpha-HSDH

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (3)

chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity

Gene Ontology

Source: GO:0106281

Synonyms: Not Available

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (3)

acetoacetyl-CoA reductase activity

Gene Ontology

Source: GO:0018454

Synonyms:

(R)-3-hydroxyacyl-CoA dehydrogenase activity
(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (3)

isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity

Gene Ontology

Source: GO:0106282

Synonyms: Not Available

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (3)

3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity

Gene Ontology

Source: GO:0047015

Synonyms:

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity
2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (3)

17-beta-hydroxysteroid dehydrogenase (NAD+) activity

Gene Ontology

Source: GO:0044594

Synonyms: Not Available

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)...HSD17B10 (Hsa)

Genes Annotated with this GO Term (9)

testosterone dehydrogenase [NAD(P)+] activity

Gene Ontology

Source: GO:0030283

Synonyms:

17beta-hydroxy steroid dehydrogenase
3(or 17)beta-hydroxysteroid dehydrogenase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (43)

isoleucine catabolic process

Gene Ontology

Source: GO:0006550

Synonyms:

isoleucine breakdown
isoleucine catabolism

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (18)

mitochondrial tRNA 3'-end processing

Gene Ontology

Source: GO:1990180

Synonyms:

tRNA 3' processing in mitochondria
tRNA 3' processing in mitochondrion

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (20)

mitochondrial tRNA methylation

Gene Ontology

Source: GO:0070901

Synonyms: Not Available

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (13)

mitochondrial ribonuclease P complex

Gene Ontology

Source: GO:0030678

Synonyms:

mitochondrial RNase P complex

Branch: cellular component

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (15)

mitochondrial tRNA 5'-end processing

Gene Ontology

Source: GO:0097745

Synonyms: Not Available

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (20)

tRNA methyltransferase complex

Gene Ontology

Source: GO:0043527

Synonyms: Not Available

Branch: cellular component

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (44)

androstan-3-alpha,17-beta-diol dehydrogenase activity

Gene Ontology

Source: GO:0047044

Synonyms:

(R)-20-hydroxysteroid dehydrogenase activity
20beta-HSD

Branch: molecular function

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (25)

testosterone dehydrogenase (NAD+) activity

Gene Ontology

Source: GO:0047035

Synonyms:

17-beta-HSD activity
17-ketoreductase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (28)

C21-steroid hormone metabolic process

Gene Ontology

Source: GO:0008207

Synonyms:

C21-steroid hormone metabolism

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (105)

pheochromocytoma

Disease

Source: DOID:0050771

Definition: An endocrine organ benign neoplasm that arises within the adrenal medulla, releasing epinephrines and norepinephrines hormones that cause either episodic or persistent high blood pressure.

Genes: hsd17b10.S (Xla)...Hsd17b10 (Mmu)...Hsd17b10 (Rno)...hsd17b10 (Dre)...HSD17B10 (Hsa)

estrogen metabolic process

Gene Ontology

Source: GO:0008210

Synonyms:

estrogen metabolism
oestrogen metabolic process

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)...hsd17b10 (Dre)

Genes Annotated with this GO Term (126)

androgen metabolic process

Gene Ontology

Source: GO:0008209

Synonyms:

androgen metabolism

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)...hsd17b10 (Dre)

Genes Annotated with this GO Term (103)

3-hydroxyacyl-CoA dehydrogenase activity

Gene Ontology

Source: GO:0003857

Synonyms:

3-oxoacyl-thioester reductase activity
L-3-hydroxyacyl CoA dehydrogenase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (33)

bile acid biosynthetic process

Gene Ontology

Source: GO:0006699

Synonyms:

bile acid anabolism
bile acid biosynthesis

Branch: biological process

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (67)

ml72

(Danio rerio)

Allele/Variant

Source: ZFIN:ZDB-ALT-210527-14

Genes: hsd17b10 (Dre)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Genes: hsd17b10 (Dre)

Gene (1)

estradiol 17-beta-dehydrogenase [NAD(P)+] activity

Gene Ontology

Source: GO:0004303

Synonyms:

17-beta-HSD activity
17-beta-estradiol dehydrogenase activity

Branch: molecular function

Genes: Hsd17b10 (Mmu)...HSD17B10 (Hsa)...Hsd17b10 (Rno)...hsd17b10 (Dre)

Genes Annotated with this GO Term (81)

osteosarcoma

Disease

Source: DOID:3347

Definition: A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus).

Genes: Hsd17b10 (Rno)...HSD17B10 (Hsa)...Hsd17b10 (Mmu)...hsd17b10 (Dre)...hsd17b10 (Xtr)

Hsap\HSD17B10^UAS.Exel

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0256670

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Hsap\HSD17B10

Construct Expressed Component: HSD17B10 (Hsa)

mitochondrial nucleoid

Gene Ontology

Source: GO:0042645

Synonyms: Not Available

Branch: cellular component

Genes: Hsd17b10 (Rno)...HSD17B10 (Hsa)...Hsd17b10 (Mmu)

Genes Annotated with this GO Term (200)

protein homotetramerization

Gene Ontology

Source: GO:0051289

Synonyms:

protein homotetramer assembly
protein homotetramer biosynthesis

Branch: biological process

Genes: Hsd17b10 (Rno)...HSD17B10 (Hsa)...Hsd17b10 (Mmu)

Genes Annotated with this GO Term (218)

Leydig cell differentiation

Gene Ontology

Source: GO:0033327

Synonyms: Not Available

Branch: biological process

Genes: Hsd17b10 (Rno)

Genes Annotated with this GO Term (45)

steroid binding

Gene Ontology

Source: GO:0005496

Synonyms: Not Available

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (477)

scu^PG115

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0129092

Genes: scu (Dme)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Gene Synonyms: HSD17B10

Gene (1)

nuclear estrogen receptor binding

Gene Ontology

Source: GO:0030331

Synonyms:

estrogen receptor binding

Branch: molecular function

Genes: Hsd17b10 (Mmu)...Hsd17b10 (Rno)

Genes Annotated with this GO Term (146)

fatty acid beta-oxidation

Gene Ontology

Source: GO:0006635

Synonyms: Not Available

Branch: biological process

Genes: Hsd17b10 (Rno)...HSD17B10 (Hsa)...Hsd17b10 (Mmu)

Genes Annotated with this GO Term (302)

chromosome Xp11.22 duplication syndrome

Disease

Source: DOID:0112037

Definition: A non-syndromic X-linked intellectual disability characterized by moderate intellectual disability and slow speech development that has_material_basis_in duplication of a small region within chromosome Xp11.22 involving both the HSD17B10 and HUWE1 genes.