Version: 8.0.0
Date: Tue Jan 28 2025
17,400 results for large1

LARGE1

(Homo sapiens)
Gene
Name: LARGE xylosyl- and glucuronyltransferase 1
Synonyms: MDC1D, LARGE, like-glycosyltransferase, like-acetylglucosaminyltransferase, KIAA0609, acetylglucosaminyltransferase-like 1A, acetylglucosaminyltransferase-like protein, MDDGA6, MDDGB6, xylosyl- and glucuronyltransferase LARGE1, glycosyltransferase-like protein LARGE1
Source: HGNC:6511
Biotype: protein coding gene
Symbol: LARGE1 (Hsa)
Symbol: LARGE1
Synonyms: xylosyl- and glucuronyltransferase LARGE1...glycosyltransferase-like protein LARGE1
Strict Orthology Symbols: large1

large1

(Danio rerio)
Gene
Name: LARGE xylosyl- and glucuronyltransferase 1
Synonyms: large
Source: ZFIN:ZDB-GENE-061204-1
Biotype: protein coding gene
Symbol: large1 (Dre)
Symbol: large1
Automated Gene Synopsis: Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1).
Strict Orthology Symbols: large1

Large1

(Rattus norvegicus)
Gene
Name: LARGE xylosyl- and glucuronyltransferase 1
Synonyms: LOC361368, Large, like-glycosyltransferase, glycosyltransferase-like protein LARGE1, xylosyl- and glucuronyltransferase LARGE1
Source: RGD:1308895
Biotype: protein coding gene
Symbol: Large1 (Rno)
Symbol: Large1
Gene Synopsis: Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1); INTERACTS WITH (+)-schisandrin
Automated Gene Synopsis: Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1).
Synonyms: glycosyltransferase-like protein LARGE1...xylosyl- and glucuronyltransferase LARGE1
Strict Orthology Symbols: large1

Large1

(Mus musculus)
Gene
Name: LARGE xylosyl- and glucuronyltransferase 1
Synonyms: fg, BPFD#36, Large, enr, like-glycosyltransferase, mKIAA0609, Mbp1, Mbp-1, myelin basic protein transgene, enervated, myd, myodystrophy, froggy
Source: MGI:1342270
Biotype: protein coding gene
Symbol: Large1 (Mmu)
Symbol: Large1
Automated Gene Synopsis: Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1).
Strict Orthology Symbols: large1
Alleles: Large1 (Mmu)...Large1 (Mmu)...Large1 (Mmu)...Large1 (Mmu)...Large1 (Mmu)

large1

(Xenopus tropicalis)
Gene
Name: LARGE xylosyl- and glucuronyltransferase 1
Synonyms: large1, mdc1d, large, LARGE xylosyl- and glucuronyltransferase 1, LOC108712551, LOC108704366
Source: Xenbase:XB-GENE-6250446
Biotype: gene
Symbol: large1
Symbol: large1 (Xtr)
Automated Gene Synopsis: Orthologous to human LARGE1 (LARGE xylosyl- and glucuronyltransferase 1).
Synonyms: large1...large1...large1
Strict Orthology Symbols: large1

LARGE1-AS1

(Homo sapiens)
Gene
Name: LARGE1 antisense RNA 1
Synonyms: Not Available
Source: HGNC:55162
Biotype: ncRNA gene
Symbol: LARGE1-AS1 (Hsa)
Symbol: LARGE1-AS1

Large1enr-Tg(MbpReg)36Pop

(Mus musculus)
Allele/Variant
Source: MGI:1889325
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1enr-Tg(MbpReg)36Pop

Large1em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7376776
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1em1Gpt

Large1myd

(Mus musculus)
Allele/Variant
Source: MGI:1856965
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: muscular dystrophy-dystroglycanopathy type B1, facioscapulohumeral muscular dystrophy
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1myd

Large1em1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7290783
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1em1Smoc

Large1vls

(Mus musculus)
Allele/Variant
Source: MGI:3510641
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: muscular dystrophy-dystroglycanopathy type B1
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1vls

Large1em8Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7301513
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1em8Gpt

Large1myd-3J

(Mus musculus)
Allele/Variant
Source: MGI:3799277
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: muscular dystrophy-dystroglycanopathy type B6
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1myd-3J

Large1myd-3J/Large1myd-3J [background:] STOCK Large1myd-3J/GrsrJ

(Mus musculus)
Model
Id: MGI:4454427
Synonyms: Not Available
Symbol: Large1/Large1 [background:] STOCK Large1/GrsrJ (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] STOCK Large1/GrsrJ

Large1vls/Large1vls [background:] B6.CAST(Cg)-Large1vls/Pjn

(Mus musculus)
Model
Id: MGI:3605225
Synonyms: Not Available
Symbol: Large1/Large1 [background:] B6.CAST(Cg)-Large1/Pjn (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] B6.CAST(Cg)-Large1/Pjn

Large1enr-Tg(MbpReg)36Pop/Large1enr-Tg(MbpReg)36Pop [background:] involves: C57BL/6J * DBA/2J * SJL/J

(Mus musculus)
Model
Id: MGI:4367254
Synonyms: Not Available
Symbol: Large1/Large1 [background:] involves: C57BL/6J * DBA/2J *
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] involves: C57BL/6J * DBA/2J *

Large1enr-Tg(MbpReg)36Pop/Large1+ [background:] involves: C57BL/6J * DBA/2J * SJL/J

(Mus musculus)
Model
Id: MGI:4367347
Synonyms: Not Available
Symbol: Large1/Large1<+> [background:] involves: C57BL/6J * DBA/2J * SJL/J (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1<+> [background:] involves: C57BL/6J * DBA/2J * SJL/J

Large1myd/Large1+ [background:] B6C3Fe a/a-Large1myd/J

(Mus musculus)
Model
Id: MGI:3607261
Synonyms: Not Available
Symbol: Large1/Large1<+> [background:] B6C3Fe a/a-Large1/J (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1<+> [background:] B6C3Fe a/a-Large1/J

Large1myd/Large1myd [background:] MYD/Le-Os +/+ Largemyd/J

(Mus musculus)
Model
Id: MGI:2175098
Synonyms: Not Available
Symbol: Large1/Large1 [background:] MYD/Le-Os +/+ Large/J (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] MYD/Le-Os +/+ Large/J

Large1m1Btlr/Large1m1Btlr [background:] C57BL/6J-Large1m1Btlr

(Mus musculus)
Model
Id: MGI:7264454
Synonyms: Not Available
Symbol: Large1/Large1 [background:] C57BL/6J-Large1 (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] C57BL/6J-Large1

Large1myd/Large1myd [background:] B6C3Fe a/a-Large1myd/J

(Mus musculus)
Model
Id: MGI:3607259
Synonyms: Not Available
Symbol: Large1/Large1 [background:] B6C3Fe a/a-Large1/J (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] B6C3Fe a/a-Large1/J

Large1myd/Large1myd [background:] B6.Cg-Large1myd/Pjn

(Mus musculus)
Model
Id: MGI:3605230
Synonyms: Not Available
Symbol: Large1/Large1 [background:] B6.Cg-Large1/Pjn (Mmu)
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] B6.Cg-Large1/Pjn

Large1enr-Tg(MbpReg)36Pop/Large1enr-Tg(MbpReg)36Pop [background:] involves: C57BL/6J * DBA/2J

(Mus musculus)
Model
Id: MGI:3844908
Synonyms: Not Available
Symbol: Large1/Large1 [background:] involves: C57BL/6J * DBA/2J (Mmu
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Large1/Large1 [background:] involves: C57BL/6J * DBA/2J

Large1m1Btlr

(Mus musculus)
Allele/Variant
Source: MGI:6725092
Genes: Large1 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: muscular dystrophy-dystroglycanopathy type B1
Variant Name: Not Available
Symbol: Large1 (Mmu)
Genes: Large1 (Mmu)
Symbol: Large1m1Btlr

lge-1

(Caenorhabditis elegans)
Gene
Name: LARGE (mouse dystroglycan glycosylation) homolog 1
Synonyms: K09C8.4, CELE_K09C8.4
Source: WB:WBGene00010716
Biotype: protein coding gene
Strict Orthology Symbols: large1

muscular dystrophy-dystroglycanopathy type B6

Disease
Source: DOID:0110637
Definition: A congenital muscular dystrophy characterized by autosomal recessive inheritance of muscular dystrophy with mental retardation and structural brain abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the LARGE gene on chromosome 22q12.
Genes: LARGE1 (Hsa)...large1 (Xtr)...Large1 (Rno)...large1 (Dre)...Large1 (Mmu)
Alleles: Large1 (Mmu)

Dysfim/Dysfim Large1myd/Large1myd [background:] involves: C57BL/6 * SJL/J

(Mus musculus)
Model
Id: MGI:5700216
Synonyms: Not Available
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Dysf/Dysf Large1/Large1 [background:] involves: C57BL/6 * SJL/J
Symbol: Dysf/Dysf Large1/Large1 [background:] involves: C57BL/6 * SJL/J (Mmu)

congenital muscular dystrophy-dystroglycanopathy type A6

Disease
Source: DOID:0111242
Definition: A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in LARGE on 22q12.3.
Genes: LARGE1 (Hsa)...large1 (Xtr)...Large1 (Rno)...large1 (Dre)...Large1 (Mmu)

xylosyltransferase activity

Gene Ontology
Source: GO:0042285
Synonyms: Not Available
Branch: molecular function
Genes: LARGE1 (Hsa)...Large1 (Rno)...large1 (Dre)...Large1 (Mmu)

muscular dystrophy-dystroglycanopathy type B1

Disease
Source: DOID:0050588
Definition: A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase.
Genes: Large1 (Rno)...large1 (Xtr)...LARGE1 (Hsa)...large1 (Dre)...Large1 (Mmu)
Alleles: Large1 (Mmu)...Large1 (Mmu)...Large1 (Mmu)

post-embryonic hindlimb morphogenesis

Gene Ontology
Source: GO:0035129
Synonyms: Not Available
Branch: biological process
Genes: LARGE1 (Hsa)...Large1 (Rno)...Large1 (Mmu)

principal sensory nucleus of trigeminal nerve development

Gene Ontology
Source: GO:0021740
Synonyms:
  • pontine nucleus development
Branch: biological process
Genes: LARGE1 (Hsa)...Large1 (Rno)...Large1 (Mmu)

Dysfim/Dysf+ Large1myd/Large1myd [background:] involves: C57BL/6 * SJL/J

(Mus musculus)
Model
Id: MGI:5700215
Synonyms: Not Available
Genes: Large1 (Mmu)
Alleles: Large1 (Mmu)
Name: Dysf/Dysf<+> Large1/Large1 [background:] involves: C57BL/6 * SJL/J
Symbol: Dysf/Dysf<+> Large1/Large1 [background:] involves: C57BL/6 * SJL/J (Mmu)

regulation of kinase activity

Gene Ontology
Source: GO:0043549
Synonyms: Not Available
Branch: biological process
Genes: Large1 (Rno)...Large1 (Mmu)...LARGE1 (Hsa)

reactive gliosis

Gene Ontology
Source: GO:0150103
Synonyms:
  • gliosis
Branch: biological process
Genes: Large1 (Rno)...Large1 (Mmu)...LARGE1 (Hsa)

LargeTn(sb-T2/Bart3)2.336Mcwi

(Rattus norvegicus)
Allele/Variant
Source: RGD:2313460
Genes: Large1 (Rno)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: glycosyltransferase-like protein LARGE1...xylosyl- and glucuronyltransferase LARGE1
Genes: Large1 (Rno)

walking behavior

Gene Ontology
Source: GO:0090659
Synonyms:
  • locomotor gait pattern
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

facioscapulohumeral muscular dystrophy

Disease
Source: DOID:11727
Definition: Not Available
Genes: large1 (Xtr)...Large1 (Rno)...LARGE1 (Hsa)...large1 (Dre)...Large1 (Mmu)
Alleles: Large1 (Mmu)

protein deglycosylation

Gene Ontology
Source: GO:0006517
Synonyms:
  • glycoprotein deglycosylation
Branch: biological process
Genes: Large1 (Rno)...Large1 (Mmu)...LARGE1 (Hsa)

localization of cell

Gene Ontology
Source: GO:0051674
Synonyms:
  • cell localization
  • establishment and maintenance of cell localization
Branch: biological process
Genes: Large1 (Rno)...Large1 (Mmu)...LARGE1 (Hsa)

skeletal muscle fiber differentiation

Gene Ontology
Source: GO:0098528
Synonyms: Not Available
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

skeletal muscle organ development

Gene Ontology
Source: GO:0060538
Synonyms: Not Available
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...large1 (Dre)...Large1 (Mmu)

connective tissue development

Gene Ontology
Source: GO:0061448
Synonyms: Not Available
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

striated muscle cell development

Gene Ontology
Source: GO:0055002
Synonyms: Not Available
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

neuromuscular process controlling posture

Gene Ontology
Source: GO:0050884
Synonyms:
  • regulation of posture
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

protein O-linked mannosylation

Gene Ontology
Source: GO:0035269
Synonyms:
  • protein amino acid O-linked mannosylation
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...large1 (Dre)...Large1 (Mmu)

glycoprotein metabolic process

Gene Ontology
Source: GO:0009100
Synonyms:
  • glycoprotein metabolism
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

F344-LargeTn(sb-T2/Bart3)2.336Mcwi

(Rattus norvegicus)
Model
Id: RGD:2313464
Synonyms: F344-LargeTn(sb-T2/Bart3)2.336Mcwi
Genes: Large1 (Rno)

glycoprotein biosynthetic process

Gene Ontology
Source: GO:0009101
Synonyms:
  • glycoprotein anabolism
  • glycoprotein biosynthesis
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)

synaptic assembly at neuromuscular junction

Gene Ontology
Source: GO:0051124
Synonyms:
  • cholinergic synaptogenesis
  • synaptic growth at neuromuscular junction
Branch: biological process
Genes: Large1 (Rno)...LARGE1 (Hsa)...Large1 (Mmu)