Version: 8.1.0Date: Fri Apr 18 2025
Category
lgl-1
(Caenorhabditis elegans)Gene
Name: Lethal Giant Larva (Drosophila Lgl) homolog 1
Synonyms: F56F10.4, CELE_F56F10.4
Source: WB:WBGene00018987
Biotype: protein coding gene
Symbol: lgl-1 (Cel)
Symbol: lgl-1
Gene Synopsis: lgl-1 encodes a protein that is related to the Drosophila tumor suppressor Lethal giant larvae (Lgl),...functions redundantly with par-2 to generate and maintain cell polarity in the early elegans embryo; lgl...PAR (PAR-3/PAR-6/PKC-3) complex most likely by associating with PAR-6 and PKC-3; the association of lgl...-1 with the PAR complex is dependent on phosphorylation of lgl-1 by PKC-3; lgl-1 is also required for...the proper localization of myosin NMY-2; lgl-1 localizes asymmetrically to the posterior cortex in a
Cross References: lgl-1...WB:lgl-1...lgl-1
LLGL2
(Homo sapiens)Gene
Name: LLGL scribble cell polarity complex component 2
Synonyms: LLGL2, scribble cell polarity complex component, LGL2, lethal giant larvae homolog 2, lethal(2) giant larvae protein homolog 2, lethal giant larvae homolog 2, scribble cell polarity complex component, Hugl-2, HGL, human giant larvae homolog
Source: HGNC:6629
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
LLGL1
(Homo sapiens)Gene
Name: LLGL scribble cell polarity complex component 1
Synonyms: HUGL, HUGL1, lethal giant larvae homolog 1, scribble cell polarity complex component, lethal(2) giant larvae protein homolog 1, Lgl1, lethal giant larvae homolog 1, DLG4, LLGL, LLGL1, scribble cell polarity complex component, HUGL-1, human homolog to the D-lgl gene protein, Mgl1
Source: HGNC:6628
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
Llgl1
(Mus musculus)Gene
Name: LLGL1 scribble cell polarity complex component
Synonyms: AI325176, expressed sequence AI325176, Llglh, Lgl1, LLGL, Rgl-1, Mgl1, Rgl1
Source: MGI:102682
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
Klra7
(Mus musculus)Gene
Name: killer cell lectin-like receptor, subfamily A, member 7
Synonyms: Ly49s2, Klra1, Ly49g, lymphocyte antigen complex, locus G, LGL-1, Ly49, Ly-49G.1, Ly-49G.3, lymphocyte antigen 49 complex, locus G, Ly-49G.2, Ly49g2, Ly49g1
Source: MGI:101901
Biotype: protein coding gene
Synonyms: LGL-1...LGL-1...LGL-1
l(2)gl
(Drosophila melanogaster)Gene
Name: lethal (2) giant larvae
Synonyms: MENE (2L)-B, l(2)giant larvae, l(2), dlgl, L(2)GL, lethal(2)-giant larvae, L(2)gl, lethal giant larvae, Lethal Giant Larvae, lgl, lethal giant larva, CG2671, l-gl, lethal giant larve, p127l(2)gl, p127[l(2)gl], Lethal giant larvae, Lethal(2)giant larvae, lethal(2)giant larvae, l[[2]]gl, gl, lethal(2) giant larvae, Suppressor of NA9 2-5, SN2-5, Lethal-giant-larvae, Lgl, LGL, Lethal giant larva, Lethal (2) giant larva, l(2) giant larva, p127, Lethal (2) giant larvae, lethal- giant-larvae, l(2) giant larvae, lethal-giant-larvae, D-LGL, lethal-2-giant larvae, Complementation group 2.1, Lethal-2-giant larvae
Source: FB:FBgn0002121
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
SRO7
(Saccharomyces cerevisiae)Gene
Name: Suppressor of rho3
Synonyms: SNI1, YPR032W, SOP1
Source: SGD:S000006236
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
Llgl2
(Mus musculus)Gene
Name: LLGL2 scribble cell polarity complex component
Synonyms: MGC:27928, RIKEN cDNA 9130006H11 gene, 9130006H11Rik, RGD1560307
Source: MGI:1918843
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
llgl2
(Danio rerio)Gene
Name: LLGL scribble cell polarity complex component 2
Synonyms: penner, lgl2, cb521, pen, wu:fl37c09, wu:fc06g08, sb:cb521, zgc:55895
Source: ZFIN:ZDB-GENE-030131-9877
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
Llgl2
(Rattus norvegicus)Gene
Name: LLGL scribble cell polarity complex component 2
Synonyms: LLGL2, scribble cell polarity complex component, LOC360661, lethal giant larvae homolog 2, lethal(2) giant larvae protein homolog 2, lethal giant larvae homolog 2, scribble cell polarity complex component, similar to Lethal giant larvae homolog 2, lethal giant larvae homolog 2 (Drosophila), RGD1560307
Source: RGD:1560307
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
Llgl1
(Rattus norvegicus)Gene
Name: LLGL scribble cell polarity complex component 1
Synonyms: Lethal giant larvae (Drosophila) homolog 1, lethal giant larvae homolog 1, scribble cell polarity complex component, Llglh, lethal(2) giant larvae protein homolog 1, LLGL, LLGL1, scribble cell polarity complex component, lethal giant larvae homolog 1 (Drosophila), Mgl1, Rgl1, rgl-1
Source: RGD:3012
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
llgl1
(Danio rerio)Gene
Name: LLGL scribble cell polarity complex component 1
Synonyms: zgc:153337
Source: ZFIN:ZDB-GENE-060825-69
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
SRO77
(Saccharomyces cerevisiae)Gene
Name: Suppressor of rho3
Synonyms: SNI2, SOP2, YBL106C
Source: SGD:S000000202
Biotype: protein coding gene
Strict Orthology Symbols: lgl-1
tm2616
(Caenorhabditis elegans)Allele/Variant
Source: WB:WBVar00251470
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: lgl-1 (Cel)
KK1105
(Caenorhabditis elegans)Model
Id: WB:WBStrain00023580
Synonyms: Not Available
Genes: lgl-1 (Cel)
llgl2
(Xenopus tropicalis)Gene
Name: LLGL2, scribble cell polarity complex component
Synonyms: LLGL2, scribble cell polarity complex component, lethal giant larvae 2, lgl2, lgl-2, llgl2
Source: Xenbase:XB-GENE-868478
Biotype: gene
Strict Orthology Symbols: lgl-1
llgl1
(Xenopus tropicalis)Gene
Name: LLGL1, scribble cell polarity complex component
Synonyms: lgl, LOC733426, LLGL1, scribble cell polarity complex component, llgl1, lethal giant larvae
Source: Xenbase:XB-GENE-868457
Biotype: gene
Strict Orthology Symbols: lgl-1
Source: GO:0032878
Synonyms: Not Available
Branch: biological process
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0051294
Synonyms:
- orienting of spindle
- spindle orientation
Branch: biological process
Genes: lgl-1 (Cel)
itIs256
(Caenorhabditis elegans)Allele/Variant
Source: WB:WBTransgene00007893
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Construct Expressed Component: lgl-1 (Cel)
Construct Regulatory Region: lgl-1 (Cel)
Constructs: [Plgl-1::lgl-1::gfp; unc-119(+)]
Gene Ontology
Source: GO:0045159
Synonyms: Not Available
Branch: molecular function
Genes: lgl-1 (Cel)
Klra7em1(IMPC)J
(Mus musculus)Allele/Variant
Source: MGI:5644523
Genes: Klra7 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: LGL-1
Klra7em1Wyok
(Mus musculus)Allele/Variant
Source: MGI:6460361
Genes: Klra7 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Gene Synonyms: LGL-1
Disease
Source: DOID:263
Definition: A urinary system cancer that is located_in the kidney.
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0006893
Synonyms:
- Golgi to plasma membrane vesicle-mediated transport
Branch: biological process
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0008593
Synonyms:
- regulation of N signaling pathway
- regulation of N signalling pathway
Branch: biological process
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0030866
Synonyms:
- actin cortex stabilization
- cortical actin cytoskeleton organisation
Branch: biological process
Genes: lgl-1 (Cel)
Disease
Source: DOID:769
Definition: An autonomic nervous system neoplasm that derives_from immature nerve cells.
Genes: lgl-1 (Cel)
Disease
Source: DOID:1319
Definition: A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain.
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0030010
Synonyms:
- bud site selection/establishment of cell polarity
- cell polarization
Branch: biological process
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0030864
Synonyms: Not Available
Branch: cellular component
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0019905
Synonyms:
- syntaxin-13 binding
- syntaxin-2 binding
Branch: molecular function
Genes: lgl-1 (Cel)
Disease
Source: DOID:305
Definition: A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0005938
Synonyms:
- cell periphery
- ectoplasm
Branch: cellular component
Genes: lgl-1 (Cel)
Gene Ontology
Source: GO:0044877
Synonyms:
- macromolecular complex binding
- protein complex binding
Branch: molecular function
Genes: lgl-1 (Cel)
(WBcel235)X:869997C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.869997C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:869997C>T
Gene Cross References: lgl-1
(WBcel235)X:868079G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.868079G>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:868079G>A
Gene Cross References: lgl-1
(WBcel235)X:868395C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.868395C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:868395C>T
Gene Cross References: lgl-1
(WBcel235)X:870691G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.870691G>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:870691G>A
Gene Cross References: lgl-1
(WBcel235)X:865063T>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.865063T>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:865063T>A
Gene Cross References: lgl-1
(WBcel235)X:867619C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.867619C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:867619C>T
Gene Cross References: lgl-1
(WBcel235)X:867786C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.867786C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:867786C>T
Gene Cross References: lgl-1
(WBcel235)X:868196C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.868196C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:868196C>T
Gene Cross References: lgl-1
(WBcel235)X:868073T>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.868073T>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:868073T>A
Gene Cross References: lgl-1
(WBcel235)X:869386C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.869386C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:869386C>T
Gene Cross References: lgl-1
(WBcel235)X:864443G>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.864443G>C
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)X:864443G>C
Gene Cross References: lgl-1
(WBcel235)X:868425C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.868425C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:868425C>T
Gene Cross References: lgl-1
(WBcel235)X:865245G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.865245G>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:865245G>A
Gene Cross References: lgl-1
(WBcel235)X:865487G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.865487G>A
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)X:865487G>A
Gene Cross References: lgl-1
(WBcel235)X:866155C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003284.9:g.866155C>T
Genes: lgl-1 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)X:866155C>T
Gene Cross References: lgl-1