Version: 8.0.0
Date: Tue Jan 28 2025
2,537 results for lrsam1

lrsam1

(Danio rerio)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: si:ch211-208h16.3
Source: ZFIN:ZDB-GENE-060526-97
Biotype: protein coding gene
Symbol: lrsam1 (Dre)
Symbol: lrsam1
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Strict Orthology Symbols: lrsam1

Lrsam1

(Mus musculus)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: RGD1564403, MGC:56830
Source: MGI:2684789
Biotype: protein coding gene
Symbol: Lrsam1 (Mmu)
Symbol: Lrsam1
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Strict Orthology Symbols: lrsam1
Alleles: Lrsam1 (Mmu)...Lrsam1 (Mmu)...Lrsam1 (Mmu)...Lrsam1 (Mmu)...Lrsam1 (Mmu)

LRSAM1

(Homo sapiens)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: E3 ubiquitin-protein ligase LRSAM1, RING-type E3 ubiquitin transferase LRSAM1, FLJ31641, CMT2P, RIFLE, TAL, leucine-rich repeat and sterile alpha motif-containing protein 1, Tsg101-associated ligase, RING finger leucine repeat rich
Source: HGNC:25135
Biotype: protein coding gene
Symbol: LRSAM1 (Hsa)
Symbol: LRSAM1
Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1
Strict Orthology Symbols: lrsam1

Lrsam1

(Rattus norvegicus)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: E3 ubiquitin-protein ligase LRSAM1, RGD1564403, LOC311866, similar to Leucine rich repeat and sterile alpha motif containing 1
Source: RGD:1564403
Biotype: protein coding gene
Symbol: Lrsam1 (Rno)
Symbol: Lrsam1
Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1); INTERACTS WITH
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Synonyms: E3 ubiquitin-protein ligase LRSAM1
Strict Orthology Symbols: lrsam1

lrsam1

(Xenopus tropicalis)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: leucine rich repeat and sterile alpha motif containing 1, lrsam1
Source: Xenbase:XB-GENE-994894
Biotype: gene
Symbol: lrsam1
Symbol: lrsam1 (Xtr)
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Synonyms: lrsam1...lrsam1...lrsam1
Strict Orthology Symbols: lrsam1

lrsam1.S

(Xenopus laevis)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: lrsam1.S, leucine rich repeat and sterile alpha motif containing 1
Source: Xenbase:XB-GENE-6486766
Biotype: gene
Symbol: lrsam1.S (Xla)
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Strict Orthology Symbols: lrsam1
Symbol: lrsam1.S

lrsam1.L

(Xenopus laevis)
Gene
Name: leucine rich repeat and sterile alpha motif containing 1
Synonyms: leucine rich repeat and sterile alpha motif containing 1, lrsam1.L
Source: Xenbase:XB-GENE-17334034
Biotype: gene
Symbol: lrsam1.L (Xla)
Automated Gene Synopsis: Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1).
Strict Orthology Symbols: lrsam1
Symbol: lrsam1.L

Lrsam1em1Bhu

(Mus musculus)
Allele/Variant
Source: MGI:7327136
Genes: Lrsam1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Lrsam1 (Mmu)
Genes: Lrsam1 (Mmu)
Symbol: Lrsam1em1Bhu

Lrsam1Gt(RRK461)Byg

(Mus musculus)
Allele/Variant
Source: MGI:4329496
Genes: Lrsam1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Charcot-Marie-Tooth disease axonal type 2P
Variant Name: Not Available
Symbol: Lrsam1 (Mmu)
Genes: Lrsam1 (Mmu)
Symbol: Lrsam1Gt(RRK461)Byg

Lrsam1Gt(RRK239)Byg

(Mus musculus)
Allele/Variant
Source: MGI:4130281
Genes: Lrsam1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Lrsam1 (Mmu)
Genes: Lrsam1 (Mmu)
Symbol: Lrsam1Gt(RRK239)Byg

Lrsam1em1(IMPC)Bay

(Mus musculus)
Allele/Variant
Source: MGI:6860358
Genes: Lrsam1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Lrsam1 (Mmu)
Genes: Lrsam1 (Mmu)
Symbol: Lrsam1em1(IMPC)Bay

Lrsam1Gt(RRK461)Byg/Lrsam1+ [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:5496260
Synonyms: Not Available
Symbol: Lrsam1/Lrsam1<+> [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Lrsam1 (Mmu)
Alleles: Lrsam1 (Mmu)
Name: Lrsam1/Lrsam1<+> [background:] involves: 129P2/OlaHsd

Lrsam1Gt(RRK461)Byg/Lrsam1Gt(RRK461)Byg [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:5496257
Synonyms: Not Available
Symbol: Lrsam1/Lrsam1 [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Lrsam1 (Mmu)
Alleles: Lrsam1 (Mmu)
Name: Lrsam1/Lrsam1 [background:] involves: 129P2/OlaHsd

Lrsam1em1(IMPC)Bay/Lrsam1em1(IMPC)Bay [background:] C57BL/6N-Lrsam1em1(IMPC)Bay/BayMmucd

(Mus musculus)
Model
Id: MGI:7388741
Synonyms: Not Available
Symbol: Lrsam1/Lrsam1 [background:] C57BL/6N-Lrsam1/BayMmucd (Mmu)
Genes: Lrsam1 (Mmu)
Alleles: Lrsam1 (Mmu)
Name: Lrsam1/Lrsam1 [background:] C57BL/6N-Lrsam1/BayMmucd

Lrsam1Gt(RRK239)Byg/Lrsam1Gt(RRK239)Byg [background:] involves: 129P2/OlaHsd

(Mus musculus)
Model
Id: MGI:5496386
Synonyms: Not Available
Symbol: Lrsam1/Lrsam1 [background:] involves: 129P2/OlaHsd (Mmu)
Genes: Lrsam1 (Mmu)
Alleles: Lrsam1 (Mmu)
Name: Lrsam1/Lrsam1 [background:] involves: 129P2/OlaHsd

Lrsam1em1Gebai

(Mus musculus)
Allele/Variant
Source: MGI:7645904
Genes: Lrsam1 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Lrsam1 (Mmu)
Genes: Lrsam1 (Mmu)
Symbol: Lrsam1em1Gebai

Charcot-Marie-Tooth disease axonal type 2P

Disease
Source: DOID:0110169
Definition: A Charcot-Marie-Tooth disease type 2 that has_material_basis_in homozygous or heterozygous mutation in the LRSAM1 gene on chromosome 9q33.
Genes: lrsam1.S (Xla)...Lrsam1 (Mmu)...Lrsam1 (Rno)...lrsam1 (Dre)...LRSAM1 (Hsa)
Alleles: Lrsam1 (Mmu)

viral budding

Gene Ontology
Source: GO:0046755
Synonyms:
  • viral capsid envelopment
  • virion budding
Branch: biological process
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

WT + MO3-lrsam1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-170130-5
Synonyms: Not Available
Genes: lrsam1 (Dre)
Name: WT + MO3-lrsam1

positive regulation of xenophagy

Gene Ontology
Source: GO:1904417
Synonyms:
  • activation of xenophagy
  • up regulation of xenophagy
Branch: biological process
Genes: Lrsam1 (Mmu)...LRSAM1 (Hsa)...Lrsam1 (Rno)

ubiquitin-dependent endocytosis

Gene Ontology
Source: GO:0070086
Synonyms:
  • ubiquitin-mediated endocytosis
Branch: biological process
Genes: Lrsam1 (Mmu)...LRSAM1 (Hsa)...Lrsam1 (Rno)

TL + MO2-lrsam1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-11597
Synonyms: Tübingen long fin, Tuebingen long fin, Tup, TLF
Genes: lrsam1 (Dre)
Name: TL + MO2-lrsam1

TL + MO1-lrsam1

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-23390
Synonyms: Tübingen long fin, Tup, Tuebingen long fin, TLF
Genes: lrsam1 (Dre)
Name: TL + MO1-lrsam1

negative regulation of endocytosis

Gene Ontology
Source: GO:0045806
Synonyms:
  • down regulation of endocytosis
  • down-regulation of endocytosis
Branch: biological process
Genes: Lrsam1 (Mmu)...Lrsam1 (Rno)...LRSAM1 (Hsa)

positive regulation of autophagosome assembly

Gene Ontology
Source: GO:2000786
Synonyms:
  • positive regulation of PAS formation
  • positive regulation of autophagic vacuole assembly
Branch: biological process
Genes: Lrsam1 (Mmu)...Lrsam1 (Rno)...LRSAM1 (Hsa)

Hsap\LRSAM1UAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0320478
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\LRSAM1
Construct Expressed Component: LRSAM1 (Hsa)

protein autoubiquitination

Gene Ontology
Source: GO:0051865
Synonyms:
  • protein auto-ubiquitination
  • protein auto-ubiquitinylation
Branch: biological process
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

hematopoietic stem cell differentiation

Gene Ontology
Source: GO:0060218
Synonyms:
  • haematopoietic stem cell differentiation
  • haemopoietic stem cell differentiation
Branch: biological process
Genes: lrsam1 (Dre)

protein catabolic process

Gene Ontology
Source: GO:0030163
Synonyms:
  • cellular protein breakdown
  • cellular protein catabolic process
Branch: biological process
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

protein polyubiquitination

Gene Ontology
Source: GO:0000209
Synonyms:
  • polyubiquitin
  • protein polyubiquitinylation
Branch: biological process
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

neuron development

Gene Ontology
Source: GO:0048666
Synonyms: Not Available
Branch: biological process
Genes: lrsam1 (Dre)

ubiquitin-protein transferase activity

Gene Ontology
Source: GO:0004842
Synonyms:
  • E2
  • E3
Branch: molecular function
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

ubiquitin protein ligase activity

Gene Ontology
Source: GO:0061630
Synonyms:
  • E3
  • ER-associated E3 ligase
Branch: molecular function
Genes: Lrsam1 (Rno)...Lrsam1 (Mmu)...LRSAM1 (Hsa)

autophagy

Gene Ontology
Source: GO:0006914
Synonyms: Not Available
Branch: biological process
Genes: Lrsam1 (Mmu)...LRSAM1 (Hsa)

(GRCh38)9:127461233C>T

(Homo sapiens)
Allele/Variant
Source: rs1168470052
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: stop_gained, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127461233C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127455594G>C

(Homo sapiens)
Allele/Variant
Source: NC_000009.12:g.127455594G>C
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127455594G>C
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127452135C>T

(Homo sapiens)
Allele/Variant
Source: rs3808831
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127452135C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127454543C>T

(Homo sapiens)
Allele/Variant
Source: rs140467743
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127454543C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127458983C>T

(Homo sapiens)
Allele/Variant
Source: rs764243243
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127458983C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127462362C>T

(Homo sapiens)
Allele/Variant
Source: rs746159728
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, stop_gained, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127462362C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127467789G>A

(Homo sapiens)
Allele/Variant
Source: rs755362254
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127467789G>A
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127473822C>T

(Homo sapiens)
Allele/Variant
Source: NC_000009.12:g.127473822C>T
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127473822C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127473824C>A

(Homo sapiens)
Allele/Variant
Source: rs765389102
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127473824C>A
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127473857G>A

(Homo sapiens)
Allele/Variant
Source: rs1419447675
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127473857G>A
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127503489T>C

(Homo sapiens)
Allele/Variant
Source: rs139260397
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127503489T>C
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127454590G>A

(Homo sapiens)
Allele/Variant
Source: rs1057521344
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127454590G>A
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127455046C>G

(Homo sapiens)
Allele/Variant
Source: rs1834465235
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127455046C>G
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127461219T>C

(Homo sapiens)
Allele/Variant
Source: rs542497718
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127461219T>C
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127455557C>T

(Homo sapiens)
Allele/Variant
Source: rs1564249268
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127455557C>T
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1

(GRCh38)9:127459024C>A

(Homo sapiens)
Allele/Variant
Source: rs1231990557
Genes: LRSAM1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)9:127459024C>A
Gene Synonyms: E3 ubiquitin-protein ligase LRSAM1...RING-type E3 ubiquitin transferase LRSAM1