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292 results for lsm3

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LSm3

(Drosophila melanogaster)

Gene

Name: Like Sm 3

Synonyms: CG31184, Lsm3, CG5926, BcDNA:RE11655, LSm3

Source: FB:FBgn0051184

Biotype: protein coding gene

Symbol: LSm3 (Dme)

Symbol: LSm3

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Synonyms: Lsm3...LSm3...Lsm3...LSm3

Strict Orthology Symbols: lsm3

Alleles: LSm3 (Dme)

Allele/Variant (33)

lsm3

(Danio rerio)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: Not Available

Source: ZFIN:ZDB-GENE-161207-2

Biotype: protein coding gene

Symbol: lsm3 (Dre)

Symbol: lsm3

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Strict Orthology Symbols: Lsm3...LSM3...LSm3

Lsm3

(Mus musculus)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: SMX4, 1010001J12Rik, 2610005D18Rik, RIKEN cDNA 2610005D18 gene, RIKEN cDNA 1010001J12 gene, RIKEN cDNA 6030401D18 gene, 6030401D18Rik, USS2

Source: MGI:1914928

Biotype: protein coding gene

Symbol: Lsm3 (Mmu)

Symbol: Lsm3

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Strict Orthology Symbols: lsm3

Alleles: Lsm3 (Mmu)

LSM3

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: SMX4, LSM3 U6 small nuclear RNA and mRNA degradation associated, LSM3 homolog, U6 small nuclear RNA associated, USS2, U6 snRNA-associated Sm-like protein LSm3, YLR438C

Source: HGNC:17874

Biotype: protein coding gene

Symbol: LSM3 (Hsa)

Symbol: LSM3

Synonyms: LSM3 U6 small nuclear RNA and mRNA degradation associated...LSM3 homolog, U6 small nuclear RNA associated...U6 snRNA-associated Sm-like protein LSm3

Strict Orthology Symbols: lsm3

Allele/Variant (6)

Lsm3

(Rattus norvegicus)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae), LSM3 U6 small nuclear RNA and mRNA degradation associated, U6 snRNA-associated Sm-like protein LSm3, LOC297455, LSM3 homolog, U6 small nuclear RNA associated

Source: RGD:1305971

Biotype: protein coding gene

Symbol: Lsm3 (Rno)

Symbol: Lsm3

Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated); PARTICIPATES

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Synonyms: LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)...LSM3 U6 small nuclear RNA and mRNA degradation associated...U6 snRNA-associated Sm-like protein LSm3...LSM3 homolog, U6 small nuclear RNA associated

Strict Orthology Symbols: lsm3

Allele/Variant (15)

LSM3

(Saccharomyces cerevisiae)

Gene

Name: Like SM

Synonyms: SMX4, YLR438C-A, USS2

Source: SGD:S000006434

Biotype: protein coding gene

Symbol: LSM3 (Sce)

Symbol: LSM3

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Strict Orthology Symbols: lsm3

Alleles: lsm3-5004 (Sce)...lsm3-5002 (Sce)...lsm3-Δ (Sce)

Allele/Variant (24)

lsm3.S

(Xenopus laevis)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: lsm3.S, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Source: Xenbase:XB-GENE-991269

Biotype: gene

Symbol: lsm3.S (Xla)

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Synonyms: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Strict Orthology Symbols: lsm3

Symbol: lsm3.S

lsm3

(Xenopus tropicalis)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: lsm3, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Source: Xenbase:XB-GENE-991265

Biotype: gene

Symbol: lsm3 (Xtr)

Symbol: lsm3

Synonyms: lsm3...lsm3...LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated...lsm3

Strict Orthology Symbols: lsm3.S...lsm3.L

Disease (4)

lsm3.L

(Xenopus laevis)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Synonyms: lsm3.L, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Source: Xenbase:XB-GENE-17339515

Biotype: gene

Symbol: lsm3.L (Xla)

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Synonyms: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

Strict Orthology Symbols: lsm3

Symbol: lsm3.L

Lsm3^em1Caox

(Mus musculus)

Allele/Variant

Source: MGI:6194617

Genes: Lsm3 (Mmu)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: Lsm3 (Mmu)

Genes: Lsm3 (Mmu)

Symbol: Lsm3^em1Caox

lsm3-5002

(Saccharomyces cerevisiae)

Allele/Variant

Source: SGD:S000278316

Genes: LSM3 (Sce)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: lsm3-5002 (Sce)

Genes: LSM3 (Sce)

Symbol: lsm3-5002

Gene (1)

lsm3-5004

(Saccharomyces cerevisiae)

Allele/Variant

Source: SGD:S000348272

Genes: LSM3 (Sce)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: lsm3-5004 (Sce)

Genes: LSM3 (Sce)

Symbol: lsm3-5004

Gene (1)

LSm3^KK108972

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0235951

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: LSm3 (Dme)

Construct Knockdown Component: LSm3 (Dme)

Symbol: LSm3^KK108972

LSm3^GD13472

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0213862

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: LSm3 (Dme)

Construct Knockdown Component: LSm3 (Dme)

Symbol: LSm3^GD13472

lsm3-Δ

(Saccharomyces cerevisiae)

Allele/Variant

Source: SGD:S000308345

Genes: LSM3 (Sce)

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: lsm3-Δ (Sce)

Genes: LSM3 (Sce)

Symbol: lsm3-Δ

Gene (1)

LSm3^HMC04113

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0299163

Genes: Not Available

Synonyms: Not Available

Variant Type: unreported

Molecular Consequence: Not Available

Diseases: Not Available

Variant Name: Not Available

Symbol: LSm3 (Dme)

Construct Knockdown Component: LSm3 (Dme)

Symbol: LSm3^HMC04113

LSM3P5

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 5

Synonyms: Not Available

Source: HGNC:44350

Biotype: pseudogene

Symbol: LSM3P5 (Hsa)

Symbol: LSM3P5

LSM3P1

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 1

Synonyms: Not Available

Source: HGNC:44346

Biotype: pseudogene

Symbol: LSM3P1 (Hsa)

Symbol: LSM3P1

LSM3P2

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 2

Synonyms: Not Available

Source: HGNC:44347

Biotype: pseudogene

Symbol: LSM3P2 (Hsa)

Symbol: LSM3P2

LSM3P4

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 4

Synonyms: Not Available

Source: HGNC:44349

Biotype: pseudogene

Symbol: LSM3P4 (Hsa)

Symbol: LSM3P4

LSM3P3

(Homo sapiens)

Gene

Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 3

Synonyms: Not Available

Source: HGNC:44348

Biotype: pseudogene

Symbol: LSM3P3 (Hsa)

Symbol: LSM3P3

Lsm3^em1Caox/Lsm3^em1Caox [background:] involves: C57BL/6J

(Mus musculus)

Model

Id: MGI:6194662

Synonyms: Not Available

Symbol: Lsm3/Lsm3 [background:] involves: C57BL/6J (Mmu)

Genes: Lsm3 (Mmu)

Alleles: Lsm3 (Mmu)

Name: Lsm3/Lsm3 [background:] involves: C57BL/6J

Gene (1)

LSm3^EP996

(Drosophila melanogaster)

Allele/Variant

Source: FB:FBal0138558

Genes: LSm3 (Dme)

Synonyms: Not Available

Variant Type: insertion

Molecular Consequence: 5_prime_UTR_variant, 3_prime_UTR_variant

Diseases: Not Available

Variant Name: Not Available

Symbol: LSm3 (Dme)

Gene Synonyms: Lsm3...LSm3

Genes: LSm3 (Dme)

Symbol: LSm3^EP996

lsm-3

(Caenorhabditis elegans)

Gene

Name: LSM Sm-like protein 3

Synonyms: CELE_Y62E10A.12, Y62E10A.12

Source: WB:WBGene00003077

Biotype: protein coding gene

Gene Synopsis: Is an ortholog of human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Automated Gene Synopsis: Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).

Strict Orthology Symbols: lsm3

ABCA12

(Homo sapiens)

Gene

Name: ATP binding cassette subfamily A member 12

Synonyms: ichthyosis congenita V, Sjogren-Larsson-like, ATP-binding cassette transporter 12, DKFZp434G232, ARCI4A, ARCI4B, ICR2B, glucosylceramide transporter ABCA12, ichthyosis congenita II, lamellar ichthyosis B, LI2, FLJ41584, ATP-binding cassette sub-family A member 12, ATP-binding cassette, sub-family A (ABC1), member 12, ICR5

Source: HGNC:14637

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

Abca3

(Drosophila melanogaster)

Gene

Name: ATP binding cassette subfamily A member 3

Synonyms: ATP binding cassette subfamily A, DmCG1718, ABCA, CG1718, dABCA

Source: FB:FBgn0031170

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

abca12

(Danio rerio)

Gene

Name: ATP-binding cassette, sub-family A (ABC1), member 12

Synonyms: si:dkey-95p16.1, cb352, sb:cb352

Source: ZFIN:ZDB-GENE-030131-9790

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

CG6052

(Drosophila melanogaster)

Gene

Name: Not Available

Synonyms: DmCG6052

Source: FB:FBgn0036747

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

abt-4

(Caenorhabditis elegans)

Gene

Name: ABC Transporter family 4

Synonyms: Y39D8C.1, CELE_Y39D8C.1

Source: WB:WBGene00000022

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

Lsm1-7-Pat1 complex

Gene Ontology

Source: GO:1990726

Synonyms: Not Available

Branch: cellular component

Genes: Lsm3 (Mmu)...lsm3 (Dre)...LSM3 (Sce)...LSm3 (Dme)...LSM3 (Hsa)

Definition: A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5,

Genes Annotated with this GO Term (39)

U6 snRNP

Gene Ontology

Source: GO:0005688

Synonyms:

snRNP U6

Branch: cellular component

Genes: Lsm3 (Mmu)...Lsm3 (Rno)...lsm3 (Dre)...LSM3 (Sce)...LSm3 (Dme)

Genes Annotated with this GO Term (63)

U6 snRNA 3'-end binding

Gene Ontology

Source: GO:0030629

Synonyms:

U6 snRNA 3' end binding

Branch: molecular function

Genes: Lsm3 (Rno)...Lsm3 (Mmu)...LSM3 (Hsa)

Genes Annotated with this GO Term (7)

Abca12

(Rattus norvegicus)

Gene

Name: ATP binding cassette subfamily A member 12

Synonyms: ATP-binding cassette, subfamily A (ABC1), member 12, ATP-binding cassette sub-family A member 12, ATP-binding cassette, sub-family A (ABC1), member 12, LOC301482, glucosylceramide transporter ABCA12

Source: RGD:1304586

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

Abca12

(Mus musculus)

Gene

Name: ATP-binding cassette, sub-family A member 12

Synonyms: 4832428G11Rik, RIKEN cDNA 4833417A11 gene, RIKEN cDNA 4832428G11 gene, 4833417A11Rik

Source: MGI:2676312

Biotype: protein coding gene

Strict Orthology Symbols: lsm3

Sm-like protein family complex

Gene Ontology

Source: GO:0120114

Synonyms: Not Available

Branch: cellular component

Genes: LSM3 (Sce)...LSM3 (Hsa)

Genes Annotated with this GO Term (619)

Lsm2-8 complex

Gene Ontology

Source: GO:0120115

Synonyms: Not Available

Branch: cellular component

Genes: LSM3 (Hsa)...Lsm3 (Rno)...Lsm3 (Mmu)

Definition: A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8,

Genes Annotated with this GO Term (21)

P-body assembly

Gene Ontology

Source: GO:0033962

Synonyms:

P body assembly
P body biogenesis

Branch: biological process

Genes: Lsm3 (Mmu)...Lsm3 (Rno)...lsm3 (Dre)...LSM3 (Sce)...LSm3 (Dme)

Genes Annotated with this GO Term (79)

Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes

HTP Dataset Index

High-Throughput (HTP) Dataset Index metadata provided by SGD

ID: GEO:GSE254761

Tags: transcriptional regulation

Summary: This SuperSeries is composed of the SubSeries listed below.

Symbol: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes

Name: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes

Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [ChIP-seq]

HTP Dataset Index

High-Throughput (HTP) Dataset Index metadata provided by SGD

ID: GEO:GSE254759

Tags: transcriptional regulation

Summary: Mediator is a well-known transcriptional co-regulator and serves as an adaptor between gene-specific regulatory proteins and RNA polymerase II. Studies on the chromatin-bound form of Mediator revealed interactions with additional protein complexes involved in various transcription-related processes, such as the Lsm2-8 complex which is part of the spliceosomal U6 snRNP complex. Here we employ ChIP-seq of chromatin associated with the Lsm3 protein and the Med1 or Med15 Mediator subunits. We identify 86 genes co-occupied by both Lsm3 and Mediator of which 73 were intron-containing ribosomal protein genes. In logarithmically growing cells, Mediator primarily binds to their promoter regions but also shows a second, less pronounced occupancy at their 3´-exons. During late exponential phase, we observe a near complete transition of Mediator from these promoters to a position in their 3´-ends, overlapping the Lsm3 binding sites approximately 250 bp downstream of their last intron-exon boundaries. Using an unbiased RNA-seq approach we show that transition of Mediator from promoters to the last exon of these genes correlates to reduction of both their mRNA levels and splicing ratios, indicating that the Mediator and Lsm complexes co-operate to control growth-regulated expression of intron-containing ribosomal protein genes at the levels of transcription initiation and splicing.

Symbol: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [ChIP-seq]

Name: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [ChIP-seq]

autosomal recessive congenital ichthyosis 4A

Disease

Source: DOID:0060712

Definition: An autosomal recessive congenital ichthyosis characterized by generalized ichthyosis and ectropion that has_material_basis_in homozygous or compound heterozygous mutation in the ABCA12 gene on chromosome 2q35.

Genes: lsm3 (Xtr)

Gene (8)

Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [RNA-seq]

HTP Dataset Index

High-Throughput (HTP) Dataset Index metadata provided by SGD

ID: GEO:GSE254760

Tags: transcriptional regulation

Symbol: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [RNA-seq]

Name: Growth regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes [RNA-seq]

autosomal recessive congenital ichthyosis 4B

Disease

Source: DOID:0060713

Definition: An autosomal recessive congenital ichthyosis characterized by severe neonatal ichthyosis with bilateral ectropion and eclabium, flattened and rudimentary nose and ears, constricting bands around the extremities and frequently lethality during infancy that has_material_basis_in homozygous or compound heterozygous mutation in the ABCA12 gene on chromosome 2q35.

Genes: lsm3 (Xtr)

U4/U6 x U5 tri-snRNP complex

Gene Ontology

Source: GO:0046540

Synonyms:

U4/U6.U5 snRNP complex

Branch: cellular component

Genes: lsm3 (Dre)...LSM3 (Hsa)...Lsm3 (Rno)...Lsm3 (Mmu)...LSM3 (Sce)

Genes Annotated with this GO Term (240)

U2-type precatalytic spliceosome

Gene Ontology

Source: GO:0071005

Synonyms:

GT-AG precatalytic spliceosome
major precatalytic spliceosome

Branch: cellular component

Genes: LSM3 (Hsa)...Lsm3 (Mmu)...Lsm3 (Rno)

Genes Annotated with this GO Term (170)

precatalytic spliceosome

Gene Ontology

Source: GO:0071011

Synonyms:

mammalian spliceosomal complex B
mammalian spliceosomal complex B1

Branch: cellular component

Genes: lsm3 (Dre)...LSM3 (Hsa)...Lsm3 (Rno)...Lsm3 (Mmu)...LSM3 (Sce)

Genes Annotated with this GO Term (378)

P-body

Gene Ontology

Source: GO:0000932

Synonyms:

P body
cytoplasmic foci

Branch: cellular component

Genes: LSM3 (Hsa)...Lsm3 (Mmu)...lsm3 (Dre)...Lsm3 (Rno)...LSM3 (Sce)

Genes Annotated with this GO Term (486)

autosomal recessive congenital ichthyosis 1

Disease

Source: DOID:0060656

Definition: An autosomal recessive congenital ichthyosis that is characterized by lamellar ichthyosis, ectropion, eclabium and hyperkeratosis that has_material_basis_in homozygous or compound heterozygous mutation in the TGM1 gene on chromosome 14q11.2.

Genes: lsm3 (Xtr)