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Date: Tue Jan 28 2025
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Gene
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HTP Dataset Index
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264
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for
mmp21
Page 1 of 6
MMP21
(
Homo sapiens
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
matrix metalloproteinase 21, matrix metalloproteinase-21, HTX7, MMP-21
Source:
HGNC:14357
Biotype:
protein coding gene
Symbol:
MMP21
(Hsa)
Symbol:
MMP21
Strict Orthology Symbols:
mmp21
Disease (1)
Allele/Variant (96)
mmp21
(
Danio rerio
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
Not Available
Source:
ZFIN:ZDB-GENE-100226-2
Biotype:
protein coding gene
Symbol:
mmp21
(Dre)
Symbol:
mmp21
Automated Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21).
Strict Orthology Symbols:
mmp21
Disease (1)
Model (7)
Mmp21
(
Rattus norvegicus
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
matrix metalloproteinase 21, matrix metalloproteinase-21, LOC293573
Source:
RGD:1309332
Biotype:
protein coding gene
Symbol:
Mmp21
(Rno)
Symbol:
Mmp21
Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21); INTERACTS WITH bisphenol A; cadmium dichloride
Automated Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21).
Strict Orthology Symbols:
mmp21
Disease (1)
Allele/Variant (17)
Mmp21
(
Mus musculus
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
Mutant line 2458, b2b2458Clo, Mutant line 873, b2b873Clo
Source:
MGI:2664387
Biotype:
protein coding gene
Symbol:
Mmp21
(Mmu)
Symbol:
Mmp21
Automated Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21).
Strict Orthology Symbols:
mmp21
Alleles:
Mmp21
(Mmu)...
Mmp21
(Mmu)
Disease (1)
Allele/Variant (151)
Model (2)
mmp21
(
Xenopus tropicalis
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
matrix metallopeptidase 21, mmp21
Source:
Xenbase:XB-GENE-960304
Biotype:
gene
Symbol:
mmp21
Symbol:
mmp21
(Xtr)
Automated Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21).
Synonyms:
mmp21
...
mmp21
...
mmp21
Strict Orthology Symbols:
mmp21
Disease (1)
mmp21.L
(
Xenopus laevis
)
Gene
Name:
matrix metallopeptidase 21
Synonyms:
matrix metallopeptidase 21, mmp21.L
Source:
Xenbase:XB-GENE-960307
Biotype:
gene
Symbol:
mmp21.L
(Xla)
Automated Gene Synopsis:
Orthologous to human
MMP21
(matrix metallopeptidase 21).
Strict Orthology Symbols:
mmp21
Symbol:
mmp21.L
Disease (1)
Mmp21
b2b873Clo
/Mmp21
b2b873Clo
[background:] C57BL/6J-Mmp21
b2b873Clo
(
Mus musculus
)
Model
Id:
MGI:5313515
Synonyms:
Not Available
Symbol:
Mmp21
/Mmp21
[background:] C57BL/6J-Mmp21
(Mmu)
Genes:
Mmp21
(Mmu)
Alleles:
Mmp21
(Mmu)
Name:
Mmp21
/
Mmp21
[background:] C57BL/6J-
Mmp21
Gene (1)
Disease (1)
Mmp21
b2b2458Clo
/Mmp21
b2b2458Clo
[background:] C57BL/6J-Mmp21
b2b2458Clo
(
Mus musculus
)
Model
Id:
MGI:5555841
Synonyms:
Not Available
Symbol:
Mmp21
/Mmp21
[background:] C57BL/6J-Mmp21
(Mmu)
Genes:
Mmp21
(Mmu)
Alleles:
Mmp21
(Mmu)
Name:
Mmp21
/
Mmp21
[background:] C57BL/6J-
Mmp21
Gene (1)
Disease (1)
Mmp21
b2b873Clo
(
Mus musculus
)
Allele/Variant
Source:
MGI:5311376
Genes:
Mmp21 (Mmu)
Synonyms:
Not Available
Variant Type:
point_mutation
Molecular Consequence:
missense_variant
Diseases:
visceral heterotaxy
Variant Name:
Not Available
Symbol:
Mmp21
(Mmu)
Genes:
Mmp21
(Mmu)
Symbol:
Mmp21
b2b873Clo
Mmp21
b2b2458Clo
(
Mus musculus
)
Allele/Variant
Source:
MGI:5554438
Genes:
Mmp21 (Mmu)
Synonyms:
Not Available
Variant Type:
point_mutation
Molecular Consequence:
missense_variant
Diseases:
visceral heterotaxy
Variant Name:
Not Available
Symbol:
Mmp21
(Mmu)
Genes:
Mmp21
(Mmu)
Symbol:
Mmp21
b2b2458Clo
MMP23A
(
Homo sapiens
)
Gene
Name:
matrix metallopeptidase 23A (pseudogene)
Synonyms:
MIFR-1, MIFR, MMP21
Source:
HGNC:7170
Biotype:
pseudogene
Synonyms:
MMP21
...
MMP21
AB + MO1-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160208-2
Synonyms:
Not Available
Genes:
mmp21
(Dre)
Name:
AB + MO1-
mmp21
Gene (1)
WT + CRISPR1-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160210-8
Synonyms:
Not Available
Genes:
mmp21
(Dre)
Name:
WT + CRISPR1-
mmp21
Gene (1)
AB + MO3-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160208-3
Synonyms:
Not Available
Genes:
mmp21
(Dre)
Name:
AB + MO3-
mmp21
Gene (1)
twu34Tg + MO1-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160208-4
Synonyms:
Tg(cmlc2:GFP)
Genes:
mmp21
(Dre)
Name:
twu34Tg + MO1-
mmp21
Gene (1)
twu34Tg + MO3-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160208-5
Synonyms:
Tg(cmlc2:GFP)
Genes:
mmp21
(Dre)
Name:
twu34Tg + MO3-
mmp21
Gene (1)
AB + MO4-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-230316-1
Synonyms:
Not Available
Genes:
mmp21
(Dre)
Name:
AB + MO4-
mmp21
Gene (1)
WT + MO4-mmp21
(
Danio rerio
)
Model
Id:
ZFIN:ZDB-FISH-160210-7
Synonyms:
Not Available
Genes:
mmp21
(Dre)
Name:
WT + MO4-
mmp21
Gene (1)
regulation of heart looping
Gene Ontology
Source:
GO:1901207
Synonyms:
regulation of cardiac looping
Branch:
biological process
Genes:
mmp21
(Dre)
Genes Annotated with this GO Term (19)
determination of heart left/right asymmetry
Gene Ontology
Source:
GO:0061371
Synonyms:
determination of cardiac left/right asymmetry
Branch:
biological process
Genes:
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)...
mmp21
(Dre)
Genes Annotated with this GO Term (424)
collagen catabolic process
Gene Ontology
Source:
GO:0030574
Synonyms:
collagen breakdown
collagen catabolism
Show All 3
Branch:
biological process
Genes:
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)...
mmp21
(Dre)
Genes Annotated with this GO Term (142)
visceral heterotaxy
Disease
Source:
DOID:0050545
Definition:
A physical disorder characterized by the abnormal distribution of the major visceral organs within the chest and abdomen.
Genes:
mmp21
(Xtr)...
mmp21
(Dre)...
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)
Alleles:
Mmp21
(Mmu)...
Mmp21
(Mmu)
Gene (303)
Allele/Variant (77)
Model (90)
coronary vasculature development
Gene Ontology
Source:
GO:0060976
Synonyms:
cardiac blood vessel development
cardiac vasculature development
Show All 5
Branch:
biological process
Genes:
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (213)
embryonic heart tube left/right pattern formation
Gene Ontology
Source:
GO:0060971
Synonyms:
Not Available
Branch:
biological process
Genes:
mmp21
(Dre)
Genes Annotated with this GO Term (33)
determination of left/right symmetry
Gene Ontology
Source:
GO:0007368
Synonyms:
determination of left/right asymmetry
Branch:
biological process
Genes:
Mmp21
(Mmu)...
mmp21
(Dre)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (756)
hematopoietic progenitor cell differentiation
Gene Ontology
Source:
GO:0002244
Synonyms:
haematopoietic progenitor cell differentiation
haemopoietic progenitor cell differentiation
Show All 3
Branch:
biological process
Genes:
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (559)
metalloendopeptidase activity
Gene Ontology
Source:
GO:0004222
Synonyms:
metalloendoprotease activity
metalloendoproteinase activity
Branch:
molecular function
Genes:
Mmp21
(Mmu)...
mmp21
(Dre)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (634)
extracellular matrix organization
Gene Ontology
Source:
GO:0030198
Synonyms:
extracellular matrix organisation
extracellular matrix organization and biogenesis
Branch:
biological process
Genes:
Mmp21
(Mmu)...
mmp21
(Dre)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (1188)
metallopeptidase activity
Gene Ontology
Source:
GO:0008237
Synonyms:
metalloprotease activity
metalloproteinase activity
Branch:
molecular function
Genes:
Mmp21
(Mmu)...
mmp21
(Dre)...
MMP21
(Hsa)
Genes Annotated with this GO Term (1124)
extracellular matrix
Gene Ontology
Source:
GO:0031012
Synonyms:
matrisome
proteinaceous extracellular matrix
Branch:
cellular component
Genes:
mmp21
(Dre)...
Mmp21
(Mmu)...
MMP21
(Hsa)...
Mmp21
(Rno)
Genes Annotated with this GO Term (2235)
peptidase activity
Gene Ontology
Source:
GO:0008233
Synonyms:
hydrolase, acting on peptide bonds
peptidase activity, acting on D-amino acid peptides
Show All 6
Branch:
molecular function
Genes:
mmp21
(Dre)...
MMP21
(Hsa)
Genes Annotated with this GO Term (3822)
proteolysis
Gene Ontology
Source:
GO:0006508
Synonyms:
ATP-dependent proteolysis
peptidolysis
Branch:
biological process
Genes:
Mmp21
(Rno)...
Mmp21
(Mmu)...
MMP21
(Hsa)...
mmp21
(Dre)
Genes Annotated with this GO Term (6877)
zinc ion binding
Gene Ontology
Source:
GO:0008270
Synonyms:
Zn binding
zinc binding
Branch:
molecular function
Genes:
Mmp21
(Rno)...
Mmp21
(Mmu)...
MMP21
(Hsa)...
mmp21
(Dre)
Genes Annotated with this GO Term (4842)
extracellular region
Gene Ontology
Source:
GO:0005576
Synonyms:
extracellular
Branch:
cellular component
Genes:
Mmp21
(Mmu)...
MMP21
(Hsa)
Genes Annotated with this GO Term (10000)
metal ion binding
Gene Ontology
Source:
GO:0046872
Synonyms:
heavy metal binding
metal binding
Branch:
molecular function
Genes:
mmp21
(Dre)...
MMP21
(Hsa)
Genes Annotated with this GO Term (10000)
(GRCh38)10:125770488G>T
(
Homo sapiens
)
Allele/Variant
Source:
rs751441192
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125770488G>T
(GRCh38)10:125774120C>A
(
Homo sapiens
)
Allele/Variant
Source:
rs918224187
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
synonymous_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125774120C>A
(GRCh38)10:125770536G>A
(
Homo sapiens
)
Allele/Variant
Source:
rs775062496
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125770536G>A
(GRCh38)10:125770567G>T
(
Homo sapiens
)
Allele/Variant
Source:
NC_000010.11:g.125770567G>T
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, stop_gained
Diseases:
Not Available
Variant Name:
(GRCh38)10:125770567G>T
(GRCh38)10:125767569C>T
(
Homo sapiens
)
Allele/Variant
Source:
rs371284820
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, synonymous_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125767569C>T
(GRCh38)10:125772621C>T
(
Homo sapiens
)
Allele/Variant
Source:
rs1013112568
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125772621C>T
(GRCh38)10:125770348C>T
(
Homo sapiens
)
Allele/Variant
Source:
rs372562000
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125770348C>T
(GRCh38)10:125773971C>A
(
Homo sapiens
)
Allele/Variant
Source:
rs1312300020
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125773971C>A
(GRCh38)10:125775773C>T
(
Homo sapiens
)
Allele/Variant
Source:
rs1320474659
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125775773C>T
(GRCh38)10:125773821G>C
(
Homo sapiens
)
Allele/Variant
Source:
rs28381286
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
non_coding_transcript_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125773821G>C
(GRCh38)10:125766928G>A
(
Homo sapiens
)
Allele/Variant
Source:
rs148927347
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125766928G>A
(GRCh38)10:125767583C>T
(
Homo sapiens
)
Allele/Variant
Source:
rs376939361
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_exon_variant, synonymous_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125767583C>T
(GRCh38)10:125766855A>G
(
Homo sapiens
)
Allele/Variant
Source:
rs532423524
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant, non_coding_transcript_variant, intron_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125766855A>G
(GRCh38)10:125774172A>C
(
Homo sapiens
)
Allele/Variant
Source:
rs1251807420
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125774172A>C
(GRCh38)10:125774193A>G
(
Homo sapiens
)
Allele/Variant
Source:
NC_000010.11:g.125774193A>G
Genes:
MMP21
(Hsa)
Synonyms:
Not Available
Variant Type:
SNP
Molecular Consequence:
missense_variant
Diseases:
Not Available
Variant Name:
(GRCh38)10:125774193A>G
Page 1 of 6
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