Version: 8.0.0
Date: Tue Jan 28 2025
1,492 results for mto1

Mto1

(Mus musculus)
Gene
Name: mitochondrial tRNA translation optimization 1
Synonyms: RIKEN cDNA 2310039H01 gene, 2310039H01Rik, RIKEN cDNA 5730419A02 gene, 5730419A02Rik
Source: MGI:1915541
Biotype: protein coding gene
Symbol: Mto1 (Mmu)
Symbol: Mto1
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Strict Orthology Symbols: mto1
Alleles: Mto1 (Mmu)...Mto1 (Mmu)...Mto1 (Mmu)...Mto1 (Mmu)...Mto1 (Mmu)

mto1

(Danio rerio)
Gene
Name: mitochondrial tRNA translation optimization 1
Synonyms: zgc:158782
Source: ZFIN:ZDB-GENE-070209-253
Biotype: protein coding gene
Symbol: mto1 (Dre)
Symbol: mto1
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Strict Orthology Symbols: MTO1...Mto1

MTO1

(Homo sapiens)
Gene
Name: mitochondrial tRNA translation optimization 1
Synonyms: COXPD10, homolog of yeast Mto1, CGI-02, mitochondrial translation optimization 1 homolog, mitochondrial MTO1-3, protein MTO1 homolog, mitochondrial
Source: HGNC:19261
Biotype: protein coding gene
Symbol: MTO1 (Hsa)
Symbol: MTO1
Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial
Strict Orthology Symbols: mto1

Mto1

(Rattus norvegicus)
Gene
Name: mitochondrial tRNA translation optimization 1
Synonyms: mitochondrial translation optimization 1 homolog (S. cerevisiae), LOC300852, mitochondrial translation optimization 1 homolog, protein MTO1 homolog, mitochondrial
Source: RGD:1308830
Biotype: protein coding gene
Symbol: Mto1 (Rno)
Symbol: Mto1
Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1); INTERACTS WITH 2,6-dinitrotoluene
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Synonyms: protein MTO1 homolog, mitochondrial
Strict Orthology Symbols: mto1

MTO1

(Saccharomyces cerevisiae)
Gene
Name: Mitochondrial Translation Optimization
Synonyms: YGL236C, IPS1
Source: SGD:S000003205
Biotype: protein coding gene
Symbol: MTO1 (Sce)
Symbol: MTO1
Gene Synopsis: mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants; human homolog MTO1
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Strict Orthology Symbols: mto1
Alleles: mto1-Δ (Sce)...mto1-M356I (Sce)

Mto1tm1a(EUCOMM)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:4432793
Genes: Mto1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Mto1 (Mmu)
Genes: Mto1 (Mmu)
Symbol: Mto1tm1a(EUCOMM)Wtsi

Mto1Gt(G019A03)Wrst

(Mus musculus)
Allele/Variant
Source: MGI:4336382
Genes: Mto1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: combined oxidative phosphorylation deficiency
Variant Name: Not Available
Symbol: Mto1 (Mmu)
Genes: Mto1 (Mmu)
Symbol: Mto1Gt(G019A03)Wrst

Mto1Gt(OST444607)Lex

(Mus musculus)
Allele/Variant
Source: MGI:4319640
Genes: Mto1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Mto1 (Mmu)
Genes: Mto1 (Mmu)
Symbol: Mto1Gt(OST444607)Lex

Mto1tm1Tomik

(Mus musculus)
Allele/Variant
Source: MGI:6281142
Genes: Mto1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Mto1 (Mmu)
Genes: Mto1 (Mmu)
Symbol: Mto1tm1Tomik

mto1-M356I

(Saccharomyces cerevisiae)
Allele/Variant
Source: SGD:S000301613
Genes: MTO1 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: mto1-M356I (Sce)
Genes: MTO1 (Sce)
Symbol: mto1-M356I

mto1-Δ

(Saccharomyces cerevisiae)
Allele/Variant
Source: SGD:S000281277
Genes: MTO1 (Sce)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: mto1-Δ (Sce)
Genes: MTO1 (Sce)
Symbol: mto1-Δ

Mto1tm2Tomik

(Mus musculus)
Allele/Variant
Source: MGI:6281144
Genes: Mto1 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Mto1 (Mmu)
Genes: Mto1 (Mmu)
Symbol: Mto1tm2Tomik

mto1zf3385/+ (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-230405-6
Synonyms: Not Available
Symbol: mto1 (AB) (Dre)
Genes: mto1 (Dre)
Name: mto1 (AB)

Mto1Gt(G019A03)Wrst/Mto1Gt(G019A03)Wrst [background:] involves: 129S2/SvPas * C57BL/6J

(Mus musculus)
Model
Id: MGI:5659847
Synonyms: Not Available
Symbol: Mto1/Mto1 [background:] involves: 129S2/SvPas * C57BL/6J (Mmu)
Genes: Mto1 (Mmu)
Alleles: Mto1 (Mmu)
Name: Mto1/Mto1 [background:] involves: 129S2/SvPas * C57BL/6J

mto1zf3385/zf3385 (AB)

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-230405-5
Synonyms: Not Available
Symbol: mto1 (AB) (Dre)
Genes: mto1 (Dre)
Name: mto1 (AB)

mtcu-2

(Caenorhabditis elegans)
Gene
Name: nuclear encoded Mitochondrial TRNA Carboxymethyl-amino-methyl modification of Uridine residues 2
Synonyms: F52H3.2, CELE_F52H3.2
Source: WB:WBGene00009944
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Strict Orthology Symbols: mto1

CG4610

(Drosophila melanogaster)
Gene
Name: Not Available
Synonyms: Not Available
Source: FB:FBgn0034735
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human MTO1 (mitochondrial tRNA translation optimization 1).
Strict Orthology Symbols: mto1

mitochondrial tRNA wobble uridine modification

Gene Ontology
Source: GO:0070899
Synonyms: Not Available
Branch: biological process
Genes: Mto1 (Mmu)...Mto1 (Rno)...mto1 (Dre)...MTO1 (Sce)...MTO1 (Hsa)

combined oxidative phosphorylation deficiency 10

Disease
Source: DOID:0111480
Definition: A combined oxidative phosphorylation deficiency characterized by hypertrophic cardiomyopathy and lactic acidosis that has_material_basis_in homozygous or compound heterozygous mutation in the MTO1 gene on chromosome 6q13.
Genes: Mto1 (Mmu)...Mto1 (Rno)...mto1 (Dre)...MTO1 (Sce)...MTO1 (Hsa)
Synonyms: mitochondrial hypertrophic cardiomyopathy with lactic acidosis due to MTO1 deficiency

combined oxidative phosphorylation deficiency

Disease
Source: DOID:0060286
Definition: A mitochondrial metabolism disease that is characterized by growth retardation, microcephaly, hypertonia, encephalopathy, cardiomyopathy and liver dysfunction.
Genes: Mto1 (Mmu)...mto1 (Dre)...MTO1 (Sce)...MTO1 (Hsa)...Mto1 (Rno)
Alleles: Mto1 (Mmu)

nonsyndromic deafness

Disease
Source: DOID:0050563
Definition: An auditory system disease that is associated with permanent hearing loss caused by damage to structures in the inner ear and/or the middle ear, which is not associated with other signs and symptoms.
Genes: mto1 (Dre)...Mto1 (Rno)...Mto1 (Mmu)...MTO1 (Sce)...MTO1 (Hsa)

tRNA wobble uridine modification

Gene Ontology
Source: GO:0002098
Synonyms: Not Available
Branch: biological process
Genes: Mto1 (Rno)...MTO1 (Hsa)...mto1 (Dre)...Mto1 (Mmu)...MTO1 (Sce)

zf3385

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-220217-4
Genes: mto1 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: mto1 (Dre)

tRNA methylation

Gene Ontology
Source: GO:0030488
Synonyms: Not Available
Branch: biological process
Genes: Mto1 (Rno)...MTO1 (Hsa)...mto1 (Dre)...Mto1 (Mmu)...MTO1 (Sce)

flavin adenine dinucleotide binding

Gene Ontology
Source: GO:0050660
Synonyms:
  • FAD or FADH2 binding
  • flavine-adenine dinucleotide binding
Branch: molecular function
Genes: MTO1 (Hsa)...mto1 (Dre)...MTO1 (Sce)...Mto1 (Rno)...Mto1 (Mmu)

tRNA processing

Gene Ontology
Source: GO:0008033
Synonyms:
  • tRNA maturation
Branch: biological process
Genes: MTO1 (Hsa)...mto1 (Dre)...MTO1 (Sce)

(GRCh38)6:73461810C>A

(Homo sapiens)
Allele/Variant
Source: rs375406465
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73461810C>A
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73466229T>C

(Homo sapiens)
Allele/Variant
Source: rs1408974756
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73466229T>C
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73473355T>G

(Homo sapiens)
Allele/Variant
Source: rs572893491
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73473355T>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73492276A>C

(Homo sapiens)
Allele/Variant
Source: rs1215865193
Genes: EEF1A1 (Hsa), MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, 3_prime_UTR_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73492276A>C
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73480708G>A

(Homo sapiens)
Allele/Variant
Source: rs947813456
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73480708G>A
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73480770A>G

(Homo sapiens)
Allele/Variant
Source: rs1344099573
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73480770A>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482085C>T

(Homo sapiens)
Allele/Variant
Source: rs144134827
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482085C>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482476A>G

(Homo sapiens)
Allele/Variant
Source: rs1417044275
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482476A>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482478C>T

(Homo sapiens)
Allele/Variant
Source: rs1322658068
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: stop_gained, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482478C>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482132T>G

(Homo sapiens)
Allele/Variant
Source: rs557440944
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, 3_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482132T>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73466567G>A

(Homo sapiens)
Allele/Variant
Source: rs989384303
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73466567G>A
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73497778A>G

(Homo sapiens)
Allele/Variant
Source: NC_000006.12:g.73497778A>G
Genes: EEF1A1 (Hsa), MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73497778A>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482259A>T

(Homo sapiens)
Allele/Variant
Source: NC_000006.12:g.73482259A>T
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482259A>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73473560C>T

(Homo sapiens)
Allele/Variant
Source: rs761373532
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73473560C>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73482237A>G

(Homo sapiens)
Allele/Variant
Source: rs1771522951
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73482237A>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73479864G>T

(Homo sapiens)
Allele/Variant
Source: NC_000006.12:g.73479864G>T
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73479864G>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73473642A>G

(Homo sapiens)
Allele/Variant
Source: rs771313508
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73473642A>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73473647G>C

(Homo sapiens)
Allele/Variant
Source: rs2150031602
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73473647G>C
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73479746G>T

(Homo sapiens)
Allele/Variant
Source: rs749351702
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73479746G>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73479771C>G

(Homo sapiens)
Allele/Variant
Source: NC_000006.12:g.73479771C>G
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73479771C>G
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73461934G>T

(Homo sapiens)
Allele/Variant
Source: rs2150024378
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant, non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73461934G>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73461950C>T

(Homo sapiens)
Allele/Variant
Source: rs938648582
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73461950C>T
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73461959G>A

(Homo sapiens)
Allele/Variant
Source: rs769700432
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73461959G>A
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial

(GRCh38)6:73473378A>C

(Homo sapiens)
Allele/Variant
Source: NC_000006.12:g.73473378A>C
Genes: MTO1 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, non_coding_transcript_variant, synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)6:73473378A>C
Gene Synonyms: homolog of yeast Mto1...protein MTO1 homolog, mitochondrial