Version: 8.0.0
Date: Tue Jan 28 2025
14,395 results for nedd4l

Nedd4l

(Rattus norvegicus)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: neural precursor cell expressed, developmentally down-regulated gene 4-like, neural precursor cell expressed, developmentally down-regulated 4-like, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase, Nedd4-2, MGC105877, E3 ubiquitin-protein ligase NEDD4-like
Source: RGD:735047
Biotype: protein coding gene
Symbol: Nedd4l (Rno)
Symbol: Nedd4l
Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase); PARTICIPATES IN transforming growth
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l

Nedd4l

(Mus musculus)
Gene
Name: neural precursor cell expressed, developmentally down-regulated gene 4-like
Synonyms: 1300012C07Rik, neural precursor cell expressed, developmentally down-regulated gene 4b, Nedd4-2, Nedd4b, RIKEN cDNA 1300012C07 gene
Source: MGI:1933754
Biotype: protein coding gene
Symbol: Nedd4l (Mmu)
Symbol: Nedd4l
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l
Alleles: Nedd4l (Mmu)...Nedd4l (Mmu)...Nedd4l (Mmu)...Nedd4l (Mmu)...Nedd4l (Mmu)

NEDD4L

(Homo sapiens)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: NEDD4-2, RSP5, NEDD4.2, neural precursor cell expressed, developmentally down-regulated gene 4-like, HECT-type E3 ubiquitin transferase NED4L, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase, hNedd4-2, FLJ33870, ubiquitin-protein ligase NEDD4-like, PVNH7, KIAA0439, ubiquitin-protein ligase Rsp5, E3 ubiquitin-protein ligase NEDD4-like
Source: HGNC:7728
Biotype: protein coding gene
Symbol: NEDD4L (Hsa)
Symbol: NEDD4L
Strict Orthology Symbols: nedd4l

nedd4l

(Danio rerio)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: nedd4b
Source: ZFIN:ZDB-GENE-051118-2
Biotype: protein coding gene
Symbol: nedd4l (Dre)
Symbol: nedd4l
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l

nedd4l

(Xenopus tropicalis)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: NEDD4 like E3 ubiquitin protein ligase, nedd4-2, nedd4l
Source: Xenbase:XB-GENE-489248
Biotype: gene
Symbol: nedd4l
Symbol: nedd4l (Xtr)
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Synonyms: nedd4l...nedd4l...nedd4l
Strict Orthology Symbols: nedd4l

nedd4l.L

(Xenopus laevis)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: NEDD4 like E3 ubiquitin protein ligase, nedd4-2, nedd4l.L
Source: Xenbase:XB-GENE-17343422
Biotype: gene
Symbol: nedd4l.L (Xla)
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l
Symbol: nedd4l.L

nedd4l.S

(Xenopus laevis)
Gene
Name: NEDD4 like E3 ubiquitin protein ligase
Synonyms: nedd4l.S, NEDD4 like E3 ubiquitin protein ligase, nedd4-2
Source: Xenbase:XB-GENE-865849
Biotype: gene
Symbol: nedd4l.S (Xla)
Automated Gene Synopsis: Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l
Symbol: nedd4l.S

Nedd4ltm1Shkr

(Mus musculus)
Allele/Variant
Source: MGI:5546607
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1Shkr

Nedd4ltm1.1Blyg

(Mus musculus)
Allele/Variant
Source: MGI:3846430
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1.1Blyg

Nedd4ltm1Toish

(Mus musculus)
Allele/Variant
Source: MGI:7432853
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1Toish

Nedd4lem3Cya

(Mus musculus)
Allele/Variant
Source: MGI:7585285
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lem3Cya

Nedd4landi

(Mus musculus)
Allele/Variant
Source: MGI:4836397
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4landi

Nedd4lem1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7302926
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lem1Gpt

Nedd4ltm1.1Hkb

(Mus musculus)
Allele/Variant
Source: MGI:4940977
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1.1Hkb

Nedd4ltm1a(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:4363447
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1a(KOMP)Wtsi

Nedd4ltm1e(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:4362848
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1e(KOMP)Wtsi

Nedd4lem1Cya

(Mus musculus)
Allele/Variant
Source: MGI:6693451
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lem1Cya

Nedd4ltm1.2Blyg

(Mus musculus)
Allele/Variant
Source: MGI:3846431
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1.2Blyg

Nedd4lem2Cya

(Mus musculus)
Allele/Variant
Source: MGI:7585284
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lem2Cya

Nedd4lem1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7262907
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lem1Smoc

Nedd4lGt(CA0066)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:3871793
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4lGt(CA0066)Wtsi

Nedd4ltm1b(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:5637104
Genes: Nedd4l (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nedd4l (Mmu)
Genes: Nedd4l (Mmu)
Symbol: Nedd4ltm1b(KOMP)Wtsi

Nedd4ltm1b(KOMP)Wtsi/Nedd4ltm1b(KOMP)Wtsi [background:] C57BL/6N-Nedd4ltm1b(KOMP)Wtsi/H

(Mus musculus)
Model
Id: MGI:5757412
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l [background:] C57BL/6N-Nedd4l/H (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l [background:] C57BL/6N-Nedd4l/H

Nedd4ltm1.2Blyg/Nedd4ltm1.2Blyg [background:] involves: 129X1/SvJ * C57BL/6J

(Mus musculus)
Model
Id: MGI:3846434
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l [background:] involves: 129X1/SvJ * C57BL/6J (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l [background:] involves: 129X1/SvJ * C57BL/6J

Nedd4ltm1Shkr/Nedd4ltm1Shkr [background:] involves: C57BL/6 * C57BL/6J

(Mus musculus)
Model
Id: MGI:5546610
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l [background:] involves: C57BL/6 * C57BL/6J (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l [background:] involves: C57BL/6 * C57BL/6J

Nedd4ltm1.1Hkb/Nedd4ltm1.1Hkb Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 [background:] involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

(Mus musculus)
Model
Id: MGI:4941006
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 [background:] involves: 129P2
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 [background:] involves: 129P2

Nedd4landi/Nedd4landi [background:] BALB/cByJ-Nedd4landi/EiJ

(Mus musculus)
Model
Id: MGI:4836960
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l [background:] BALB/cByJ-Nedd4l/EiJ (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l [background:] BALB/cByJ-Nedd4l/EiJ

Nedd4ltm1Shkr/Nedd4ltm1Shkr [background:] involves: 129 * C57BL/6 * C57BL/6J

(Mus musculus)
Model
Id: MGI:5546611
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l [background:] involves: 129 * C57BL/6 * C57BL/6J (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l [background:] involves: 129 * C57BL/6 * C57BL/6J

Nedd4ltm1Shkr/Nedd4l+ [background:] involves: C57BL/6 * C57BL/6J

(Mus musculus)
Model
Id: MGI:5546612
Synonyms: Not Available
Symbol: Nedd4l/Nedd4l<+> [background:] involves: C57BL/6 * C57BL/6J (Mmu)
Genes: Nedd4l (Mmu)
Alleles: Nedd4l (Mmu)
Name: Nedd4l/Nedd4l<+> [background:] involves: C57BL/6 * C57BL/6J

Y92H12A.2

(Caenorhabditis elegans)
Gene
Name: E3 ubiquitin-protein ligase
Synonyms: CELE_Y92H12A.2
Source: WB:WBGene00022358
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human NEDD4 (NEDD4 E3 ubiquitin protein ligase) and NEDD4L (NEDD4 like E3 ubiquitin
Automated Gene Synopsis: Orthologous to human NEDD4 (NEDD4 E3 ubiquitin protein ligase) and NEDD4L (NEDD4 like E3 ubiquitin protein
Strict Orthology Symbols: nedd4l

RSP5

(Saccharomyces cerevisiae)
Gene
Name: Reverses Spt- Phenotype
Synonyms: UBY1, MUT2, HPG1, SMM1, YER125W, MDP1, NPI1
Source: SGD:S000000927
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human NEDD4 (NEDD4 E3 ubiquitin protein ligase); NEDD4L (NEDD4 like E3 ubiquitin protein
Strict Orthology Symbols: nedd4l

Nedd4

(Drosophila melanogaster)
Gene
Name: Nedd4
Synonyms: nedd4, ACN62428.1, CG32184, CG7555, NEDD4, dNedd4, dNedd4-1, DNedd4, CG42279
Source: FB:FBgn0259174
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to several human genes including NEDD4L (NEDD4 like E3 ubiquitin protein ligase).
Strict Orthology Symbols: nedd4l

periventricular nodular heterotopia

Disease
Source: DOID:0050454
Definition: A congenital nervous system abnormality characterized by non proper migration of neurons during the early development of the fetal brain.
Genes: nedd4l (Dre)...nedd4l.S (Xla)...NEDD4L (Hsa)...nedd4l.L (Xla)...nedd4l (Xtr)

negative regulation of sodium ion transmembrane transport

Gene Ontology
Source: GO:1902306
Synonyms:
  • down regulation of sodium ion membrane transport
  • down regulation of sodium ion transmembrane transport
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

sodium channel inhibitor activity

Gene Ontology
Source: GO:0019871
Synonyms: Not Available
Branch: molecular function
Genes: nedd4l (Dre)...NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of potassium ion transmembrane transporter activity

Gene Ontology
Source: GO:1901017
Synonyms:
  • down regulation of potassium ion transmembrane transporter activity
  • down regulation of potassium transporter activity
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

positive regulation of caveolin-mediated endocytosis

Gene Ontology
Source: GO:2001288
Synonyms:
  • positive regulation of caveolae-dependent endocytosis
  • positive regulation of caveolae-mediated endocytosis
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

regulation of potassium ion transmembrane transporter activity

Gene Ontology
Source: GO:1901016
Synonyms:
  • regulation of potassium transporter activity
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

regulation of sodium ion transmembrane transport

Gene Ontology
Source: GO:1902305
Synonyms:
  • regulation of sodium ion membrane transport
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

regulation protein catabolic process at postsynapse

Gene Ontology
Source: GO:0140252
Synonyms: Not Available
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

positive regulation of cation channel activity

Gene Ontology
Source: GO:2001259
Synonyms:
  • positive regulation of cation diffusion facilitator activity
  • positive regulation of nonselective cation channel activity
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of sodium ion transmembrane transporter activity

Gene Ontology
Source: GO:2000650
Synonyms:
  • negative regulation of sodium transporter activity
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

regulation of membrane depolarization

Gene Ontology
Source: GO:0003254
Synonyms: Not Available
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of sodium ion import across plasma membrane

Gene Ontology
Source: GO:1903783
Synonyms:
  • down regulation of sodium ion import across plasma membrane
  • down-regulation of sodium ion import across plasma membrane
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)

Liddle syndrome

Disease
Source: DOID:0050477
Definition: A renal tubular transport disease that is characterized by hypertension and hypokalemia caused by dysregulation of epithelial sodium channels causing over expression of the channel.
Genes: nedd4l (Dre)...NEDD4L (Hsa)...nedd4l (Xtr)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of sodium ion transport

Gene Ontology
Source: GO:0010766
Synonyms: Not Available
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

potassium channel inhibitor activity

Gene Ontology
Source: GO:0019870
Synonyms: Not Available
Branch: molecular function
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

regulation of bicellular tight junction assembly

Gene Ontology
Source: GO:2000810
Synonyms:
  • regulation of tight junction formation
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of potassium ion transmembrane transport

Gene Ontology
Source: GO:1901380
Synonyms:
  • down regulation of potassium ion transmembrane transport
  • down-regulation of potassium ion transmembrane transport
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)

negative regulation of protein localization to cell surface

Gene Ontology
Source: GO:2000009
Synonyms:
  • negative regulation of protein localisation at cell surface
  • negative regulation of protein localization at cell surface
Branch: biological process
Genes: NEDD4L (Hsa)...Nedd4l (Rno)...Nedd4l (Mmu)