Version: 8.0.0Date: Tue Jan 28 2025
Category
nphp3
(Danio rerio)Gene
Name: nephronophthisis 3
Synonyms: si:dkey-56l10.1
Source: ZFIN:ZDB-GENE-091204-117
Biotype: protein coding gene
Symbol: nphp3 (Dre)
Symbol: nphp3
Automated Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3).
Strict Orthology Symbols: nphp3
NPHP3
(Homo sapiens)Gene
Name: nephrocystin 3
Synonyms: cilia and flagella associated protein 31, RHPD1, DKFZp781K1312, MGC78666, MKS7, NPH3, KIAA2000, SLSN3, Meckel syndrome, type 7, RHPD, DKFZp667K242, FLJ36696, nephrocystin-3, nephronophthisis 3 (adolescent), FLJ30691, CFAP31
Source: HGNC:7907
Biotype: protein coding gene
Symbol: NPHP3 (Hsa)
Symbol: NPHP3
Strict Orthology Symbols: nphp3
Nphp3
(Rattus norvegicus)Gene
Name: nephrocystin 3
Synonyms: LOC363126, nephrocystin-3, nephronophthisis 3 (adolescent), similar to nephrocystin 3, RGD1563856
Source: RGD:1563856
Biotype: protein coding gene
Symbol: Nphp3 (Rno)
Symbol: Nphp3
Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3); INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; cadmium
Automated Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3).
Strict Orthology Symbols: nphp3
Nphp3
(Mus musculus)Gene
Name: nephronophthisis 3 (adolescent)
Synonyms: RIKEN cDNA 3632410F03 gene, expressed sequence AI550417, polycystic kidney disease, AI550417, pcy, 3632410F03Rik, D330020E01Rik, nephrocystin 3, RGD1563856, RIKEN cDNA D330020E01 gene
Source: MGI:1921275
Biotype: protein coding gene
Symbol: Nphp3 (Mmu)
Symbol: Nphp3
Automated Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3).
Strict Orthology Symbols: nphp3
Alleles: Nphp3
nphp3
(Xenopus tropicalis)Gene
Name: nephronophthisis 3 (adolescent)
Synonyms: nephrocystin-3, nephronophthisis 3 (adolescent), nphp3, nph3
Source: Xenbase:XB-GENE-487873
Biotype: gene
Symbol: nphp3
Symbol: nphp3 (Xtr)
Automated Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3).
Synonyms: nphp3...nphp3...nphp3
Strict Orthology Symbols: nphp3
NPHP3-ACAD11
(Homo sapiens)Gene
Name: NPHP3-ACAD11 readthrough (NMD candidate)
Synonyms: NPHP3
Source: HGNC:48351
Biotype: ncRNA gene
Symbol: NPHP3-ACAD11 (Hsa)
Gene Synopsis: This locus represents naturally occurring read-through transcription between the neighboring NPHP3 (nephronophthisis
Synonyms: NPHP3...NPHP3
Symbol: NPHP3-ACAD11
NPHP3-AS1
(Homo sapiens)Gene
Name: NPHP3 antisense RNA 1
Synonyms: NCRNA00119
Source: HGNC:24129
Biotype: ncRNA gene
Symbol: NPHP3-AS1 (Hsa)
Symbol: NPHP3-AS1
nphp3.L
(Xenopus laevis)Gene
Name: nephronophthisis 3 (adolescent)
Synonyms: nephrocystin-3, nephronophthisis 3 (adolescent), nph3, nphp3.L
Source: Xenbase:XB-GENE-865745
Biotype: gene
Symbol: nphp3.L (Xla)
Automated Gene Synopsis: Orthologous to human NPHP3 (nephrocystin 3).
Strict Orthology Symbols: nphp3
Symbol: nphp3.L
Nphp3em1(IMPC)J
(Mus musculus)Allele/Variant
Source: MGI:6273809
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3em1(IMPC)J
Nphp3em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7462229
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3em1Gpt
Nphp3pol
(Mus musculus)Allele/Variant
Source: MGI:3847130
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3pol
Nphp3tm1Cbe
(Mus musculus)Allele/Variant
Source: MGI:3809285
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3tm1Cbe
Nphp3pcy
(Mus musculus)Allele/Variant
Source: MGI:1856987
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: autosomal dominant polycystic kidney disease, nephronophthisis 3
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3pcy
Nphp3tm1.1Nakaj
(Mus musculus)Allele/Variant
Source: MGI:6159873
Genes: Nphp3 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Nphp3
Genes: Nphp3 (Mmu)
Symbol: Nphp3tm1.1Nakaj
Nphp3pcy/Nphp3pcy [background:] D2.KK-Nphp3pcy
(Mus musculus)Model
Id: MGI:3800130
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] D2.KK-Nphp3 (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] D2.KK-Nphp3
Id: MGI:6492988
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] C57BL/6NJ-Nphp3/Mmjax (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] C57BL/6NJ-Nphp3/Mmjax
Nphp3pcy/Nphp3pcy [background:] either: D2.KK-Nphp3pcy or (involves: DBA/2Fg * DBA/2J * KK)
(Mus musculus)Model
Id: MGI:3583124
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] either: D2.KK-Nphp3 or (involves: DBA/2Fg * DBA/2J * KK) (Mmu
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] either: D2.KK-Nphp3 or (involves: DBA/2Fg * DBA/2J * KK)
Nphp3pcy/Nphp3pcy [background:] involves: DBA/2Fg * KK
(Mus musculus)Model
Id: MGI:3583122
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] involves: DBA/2Fg * KK (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] involves: DBA/2Fg * KK
Model
Id: MGI:3847131
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] C57BL/6JSfdAnu-Nphp3/Anu (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] C57BL/6JSfdAnu-Nphp3/Anu
Model
Id: MGI:3809288
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] involves: C57BL/6 * CD-1 * KK/Upj (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] involves: C57BL/6 * CD-1 * KK/Upj
Model
Id: MGI:3809286
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] B6.129P2-Nphp3 (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] B6.129P2-Nphp3
Id: MGI:3800129
Synonyms: Not Available
Symbol: Nphp3/Nphp3 Tg(MtTGFA)42Lmb/0 [background:] involves: CD-1 * DBA/2Fg * KK (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 Tg(MtTGFA)42Lmb/0 [background:] involves: CD-1 * DBA/2Fg * KK
Model
Id: MGI:6696837
Synonyms: Not Available
Symbol: Nphp3/Nphp3<+> [background:] C57BL/6NJ-Nphp3/Mmjax (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3<+> [background:] C57BL/6NJ-Nphp3/Mmjax
Nphp3pcy/Nphp3pcy [background:] KK-Nphp3pcy
(Mus musculus)Model
Id: MGI:3583121
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] KK-Nphp3 (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] KK-Nphp3
Nphp3pcy/Nphp3pcy [background:] involves: KK
(Mus musculus)Model
Id: MGI:3583125
Synonyms: Not Available
Symbol: Nphp3/Nphp3 [background:] involves: KK (Mmu)
Genes: Nphp3 (Mmu)
Alleles: Nphp3
Name: Nphp3/Nphp3 [background:] involves: KK
Disease
Source: DOID:0111114
Definition: A nephronophthisis that has_material_basis_in homozygous or compound heterozygous mutation in the NPHP3 gene on chromosome 3q22.
Genes: nphp3.L (Xla)...Nphp3 (Rno)...Nphp3 (Mmu)...nphp3 (Dre)...nphp3 (Xtr)
Synonyms: NPHP3...NPHP3
Alleles: Nphp3
ACAD11
(Homo sapiens)Gene
Name: acyl-CoA dehydrogenase family member 11
Synonyms: acyl-Coenzyme A dehydrogenase family, member 11, MGC150619, ACAD-11, FLJ12592, acyl-CoA dehydrogenase family, member 11, putative acyl-CoA dehydrogenase, 62113 protein
Source: HGNC:30211
Biotype: protein coding gene
Gene Synopsis: Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis
Gene Ontology
Source: GO:0071909
Synonyms: Not Available
Branch: biological process
Genes: Nphp3 (Rno)...Nphp3 (Mmu)...NPHP3 (Hsa)
Disease
Source: DOID:0070121
Definition: A Meckel syndrome that has_material_basis_in an autosomal recessive mutation of the NPHP3 gene on chromosome 3q22.1.
Genes: nphp3.L (Xla)...Nphp3 (Rno)...Nphp3 (Mmu)...nphp3 (Dre)...nphp3 (Xtr)
Source: DOID:0060259
Definition: A physical disorder characterized by pancreatic fibrosis, renal dysplasia and hepatic dysgenesis; it is usual fatal soon after birth.
Genes: nphp3 (Dre)...nphp3 (Xtr)...NPHP3 (Hsa)...Nphp3 (Rno)...Nphp3 (Mmu)
Gene Ontology
Source: GO:0048496
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Rno)...Nphp3 (Mmu)
Source: GO:2000095
Synonyms:
- regulation of PCP pathway
- regulation of Wnt receptor signaling pathway, planar cell polarity pathway
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Rno)...Nphp3 (Mmu)
Gene Ontology
Source: GO:0072189
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Rno)...Nphp3 (Mmu)
Gene Ontology
Source: GO:0071908
Synonyms: Not Available
Branch: biological process
Genes: Nphp3 (Rno)...Nphp3 (Mmu)...NPHP3 (Hsa)
Gene Ontology
Source: GO:0097543
Synonyms:
- Inv compartment of the cilium
- cilial inversin compartment
Branch: cellular component
Genes: nphp3 (Dre)...NPHP3 (Hsa)...Nphp3 (Rno)...Nphp3 (Mmu)
WT + MO3-nphp3
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-2870
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: WT + MO3-nphp3
Disease
Source: DOID:12712
Definition: A kidney disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy).
Genes: nphp3 (Dre)...nphp3 (Xtr)...Nphp3 (Mmu)...Nphp3 (Rno)...NPHP3 (Hsa)
Gene Ontology
Source: GO:0071910
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Mmu)...Nphp3 (Rno)
sa45010
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-190123-630
Genes: nphp3 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: nphp3 (Dre)
WT + MO2-nphp3
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-17358
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: WT + MO2-nphp3
WT + MO1-nphp3 + MO2-invs
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-5547
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: WT + MO1-nphp3 + MO2-invs
li1Tg + MO2-nphp3
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-19467
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: li1Tg + MO2-nphp3
Gene Ontology
Source: GO:0003283
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Mmu)...Nphp3 (Rno)
Gene Ontology
Source: GO:0035469
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Mmu)...Nphp3 (Rno)
WT + MO1-nphp3
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-20987
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: WT + MO1-nphp3
li1Tg + MO1-anks6 + MO2-nphp3
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-14073
Synonyms: Not Available
Genes: nphp3 (Dre)
Name: li1Tg + MO1-anks6 + MO2-nphp3
Gene Ontology
Source: GO:0060993
Synonyms: Not Available
Branch: biological process
Genes: NPHP3 (Hsa)...Nphp3 (Mmu)...Nphp3 (Rno)
Gene Ontology
Source: GO:0060026
Synonyms: Not Available
Branch: biological process
Genes: nphp3 (Dre)...Nphp3 (Mmu)...Nphp3 (Rno)...NPHP3 (Hsa)
Gene Ontology
Source: GO:0060027
Synonyms: Not Available
Branch: biological process
Genes: Nphp3 (Mmu)...Nphp3 (Rno)...NPHP3 (Hsa)
Source: DOID:898
Definition: A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion.
Genes: Nphp3 (Mmu)...nphp3 (Xtr)...nphp3 (Dre)...Nphp3 (Rno)...NPHP3 (Hsa)
Alleles: Nphp3