Version: 8.0.0
Date: Tue Jan 28 2025
33 results for ppardb

ppardb

(Danio rerio)
Gene
Name: peroxisome proliferator-activated receptor delta b
Synonyms: NUC1, wu:fk47c06, NR1C2-B, nr1c2b, pparb2, fk47c06, PPAR[b](II), fc59g04, FAAR, wu:fc59g04
Source: ZFIN:ZDB-GENE-000112-47
Biotype: protein coding gene
Symbol: ppardb (Dre)
Symbol: ppardb

PPARD

(Homo sapiens)
Gene
Name: peroxisome proliferator activated receptor delta
Synonyms: PPAR-delta, nuclear receptor subfamily 1 group C member 2, PPAR-beta, NUCI, peroxisome proliferator-activated receptor delta, peroxisome proliferator-activated receptor beta, FAAR, NR1C2, NUCII, NUC1, peroxisome proliferator-activated nuclear receptor beta/delta variant 2, nuclear hormone receptor 1, PPARB, MGC3931, PPARD/MYO1D fusion
Source: HGNC:9235
Biotype: protein coding gene
Strict Orthology Symbols: ppardb

Ppard

(Mus musculus)
Gene
Name: peroxisome proliferator activator receptor delta
Synonyms: PPAR-delta, PPARdelta/beta, NUC1, Nr1c2, Peroxisome proliferator-activated receptor beta, Pparb, Pparb/d
Source: MGI:101884
Biotype: protein coding gene
Strict Orthology Symbols: ppardb

nhr-2

(Caenorhabditis elegans)
Gene
Name: Nuclear Hormone Receptor family 2
Synonyms: crf-2, C32F10.6, CELE_C32F10.6
Source: WB:WBGene00003601
Biotype: protein coding gene
Strict Orthology Symbols: ppardb

Ppard

(Rattus norvegicus)
Gene
Name: peroxisome proliferator-activated receptor delta
Synonyms: Peroxisome proliferator activator receptor delta, peroxisome proliferator activated receptor delta, peroxisome proliferator activator receptor, delta, peroxisome proliferator activator receptor beta, Pparb
Source: RGD:3370
Biotype: protein coding gene
Strict Orthology Symbols: ppardb

ppard

(Xenopus tropicalis)
Gene
Name: peroxisome proliferator activated receptor delta
Synonyms: peroxisome proliferator activated receptor delta, xPPAR beta, PPAR-beta, ppard, pparb
Source: Xenbase:XB-GENE-481495
Biotype: gene
Strict Orthology Symbols: ppardb

la016313Tg

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-120806-8692
Genes: ppardb (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: ppardb (Dre)

positive regulation of fatty acid metabolic process

Gene Ontology
Source: GO:0045923
Synonyms:
  • activation of fatty acid metabolic process
  • positive regulation of fatty acid metabolism
Branch: biological process
Genes: ppardb (Dre)

biliary tract cancer

Disease
Source: DOID:4607
Definition: A hepatobiliary system cancer that results_in malignant growth located_in the gallbladder or located_in the bile duct.
Genes: ppardb (Dre)

negative regulation of cholesterol storage

Gene Ontology
Source: GO:0010887
Synonyms:
  • negative regulation of cholesterol sequestration
Branch: biological process
Genes: ppardb (Dre)

hormone-mediated signaling pathway

Gene Ontology
Source: GO:0009755
Synonyms:
  • hormone mediated signalling
Branch: biological process
Genes: ppardb (Dre)

intracellular receptor signaling pathway

Gene Ontology
Source: GO:0030522
Synonyms:
  • intracellular receptor mediated signaling pathway
  • intracellular receptor-mediated signaling pathway
Branch: biological process
Genes: ppardb (Dre)

nuclear receptor activity

Gene Ontology
Source: GO:0004879
Synonyms:
  • 1,25-(OH)2D3 receptor activity
  • 9-cis retinoic acid receptor activity
Branch: molecular function
Genes: ppardb (Dre)

fatty acid metabolic process

Gene Ontology
Source: GO:0006631
Synonyms:
  • fatty acid metabolism
Branch: biological process
Genes: ppardb (Dre)

negative regulation of inflammatory response

Gene Ontology
Source: GO:0050728
Synonyms:
  • anti-inflammatory response
  • down regulation of inflammatory response
Branch: biological process
Genes: ppardb (Dre)

Huntington's disease

Disease
Source: DOID:12858
Definition: A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.
Genes: ppardb (Dre)

DNA-binding transcription repressor activity, RNA polymerase II-specific

Gene Ontology
Source: GO:0001227
Synonyms:
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
  • RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription
Branch: molecular function
Genes: ppardb (Dre)

pancreatic cancer

Disease
Source: DOID:1793
Definition: An endocrine gland cancer located_in the pancreas.
Genes: ppardb (Dre)

sequence-specific DNA binding

Gene Ontology
Source: GO:0043565
Synonyms:
  • sequence specific DNA binding
Branch: molecular function
Genes: ppardb (Dre)

sa34394

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-3079
Genes: ppardb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_acceptor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: ppardb (Dre)

sa2434

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-11909
Genes: ppardb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: ppardb (Dre)

sa41198

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-7250
Genes: ppardb (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: ppardb (Dre)

DNA-binding transcription factor activity

Gene Ontology
Source: GO:0003700
Synonyms:
  • DNA binding transcription factor activity
  • bacterial-type DNA binding transcription factor activity
Branch: molecular function
Genes: ppardb (Dre)

cell differentiation

Gene Ontology
Source: GO:0030154
Synonyms: Not Available
Branch: biological process
Genes: ppardb (Dre)

type 2 diabetes mellitus

Disease
Source: DOID:9352
Definition: A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Genes: ppardb (Dre)

positive regulation of transcription by RNA polymerase II

Gene Ontology
Source: GO:0045944
Synonyms:
  • activation of global transcription from RNA polymerase II promoter
  • activation of transcription from RNA polymerase II promoter
Branch: biological process
Genes: ppardb (Dre)

regulation of DNA-templated transcription

Gene Ontology
Source: GO:0006355
Synonyms:
  • regulation of cellular transcription, DNA-dependent
  • regulation of gene-specific transcription
Branch: biological process
Genes: ppardb (Dre)

RNA polymerase II cis-regulatory region sequence-specific DNA binding

Gene Ontology
Source: GO:0000978
Synonyms:
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • RNA polymerase II distal enhancer sequence-specific DNA binding
Branch: molecular function
Genes: ppardb (Dre)

zinc ion binding

Gene Ontology
Source: GO:0008270
Synonyms:
  • Zn binding
  • zinc binding
Branch: molecular function
Genes: ppardb (Dre)

DNA binding

Gene Ontology
Source: GO:0003677
Synonyms:
  • microtubule/chromatin interaction
  • plasmid binding
Branch: molecular function
Genes: ppardb (Dre)

nucleus

Gene Ontology
Source: GO:0005634
Synonyms:
  • cell nucleus
  • horsetail nucleus
Branch: cellular component
Genes: ppardb (Dre)

negative regulation of transcription by RNA polymerase II

Gene Ontology
Source: GO:0000122
Synonyms:
  • down regulation of global transcription from RNA polymerase II promoter
  • down regulation of transcription from RNA polymerase II promoter
Branch: biological process
Genes: ppardb (Dre)

metal ion binding

Gene Ontology
Source: GO:0046872
Synonyms:
  • heavy metal binding
  • metal binding
Branch: molecular function
Genes: ppardb (Dre)