Version: 8.0.0
Date: Tue Jan 28 2025
1,740 results for prpf6

prpf6

(Danio rerio)
Gene
Name: PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
Synonyms: fc12b02, zgc:65913, c20orf14, wu:fc12b02, wu:fa05f07
Source: ZFIN:ZDB-GENE-030131-2575
Biotype: protein coding gene
Symbol: prpf6 (Dre)
Symbol: prpf6
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6

Prpf6

(Rattus norvegicus)
Gene
Name: pre-mRNA processing factor 6
Synonyms: U5-102 kDa protein, PRP6 homolog, PRP6 pre-mRNA processing factor 6 homolog, pre-mRNA-processing factor 6, similar to RIKEN cDNA 1190003A07, LOC366276, U5 snRNP-associated 102 kDa protein, MGC156816, PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae), PRP6 pre-mRNA splicing factor 6 homolog, RGD1307103, PRP6 pre-mRNA splicing factor 6 homolog (S. cerevisiae)
Source: RGD:1307103
Biotype: protein coding gene
Symbol: Prpf6 (Rno)
Symbol: Prpf6
Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6); PARTICIPATES IN spliceosome pathway; INTERACTS
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6

Prpf6

(Mus musculus)
Gene
Name: pre-mRNA splicing factor 6
Synonyms: 1190003A07Rik, RIKEN cDNA 2610031L17 gene, ANT-1, MGC:38351, U5-102K, RIKEN cDNA 1190003A07 gene, 2610031L17Rik, MGC:11655, RGD1307103, MGC:36967
Source: MGI:1922946
Biotype: protein coding gene
Symbol: Prpf6 (Mmu)
Symbol: Prpf6
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6
Alleles: Prpf6 (Mmu)...Prpf6 (Mmu)...Prpf6 (Mmu)

PRPF6

(Homo sapiens)
Gene
Name: pre-mRNA processing factor 6
Synonyms: androgen receptor N-terminal domain transactivating protein-1, chromosome 20 open reading frame 14, C20orf14, p102 U5 small nuclear ribonucleoprotein particle-binding protein, Prp6, hPrp6, U5-102 kDa protein, PRP6 homolog, TOM, ANT-1, PRP6 pre-mRNA processing factor 6 homolog, pre-mRNA-processing factor 6, ANT1, putative mitochondrial outer membrane protein import receptor, U5-102K, U5 snRNP-associated 102 kDa protein, androgen receptor N-terminal domain-transactivating protein 1, RP60, SNRNP102
Source: HGNC:15860
Biotype: protein coding gene
Symbol: PRPF6 (Hsa)
Symbol: PRPF6
Strict Orthology Symbols: prpf6

prpf6

(Xenopus tropicalis)
Gene
Name: pre-mRNA processing factor 6
Synonyms: prpf6, pre-mRNA processing factor 6
Source: Xenbase:XB-GENE-997713
Biotype: gene
Symbol: prpf6
Symbol: prpf6 (Xtr)
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Synonyms: prpf6...prpf6...prpf6
Strict Orthology Symbols: prpf6

prpf6.L

(Xenopus laevis)
Gene
Name: pre-mRNA processing factor 6
Synonyms: prpf6.L, pre-mRNA processing factor 6
Source: Xenbase:XB-GENE-997718
Biotype: gene
Symbol: prpf6.L (Xla)
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6
Symbol: prpf6.L

prpf6.S

(Xenopus laevis)
Gene
Name: pre-mRNA processing factor 6
Synonyms: prpf6.S, pre-mRNA processing factor 6
Source: Xenbase:XB-GENE-17343407
Biotype: gene
Symbol: prpf6.S (Xla)
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6
Symbol: prpf6.S

Prpf6em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7304812
Genes: Prpf6 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Prpf6 (Mmu)
Genes: Prpf6 (Mmu)
Symbol: Prpf6em1Gpt

Prpf6tm1.1(KOMP)Vlcg

(Mus musculus)
Allele/Variant
Source: MGI:5447745
Genes: Prpf6 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Prpf6 (Mmu)
Genes: Prpf6 (Mmu)
Symbol: Prpf6tm1.1(KOMP)Vlcg

Prpf6tm1(KOMP)Vlcg

(Mus musculus)
Allele/Variant
Source: MGI:5008129
Genes: Prpf6 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Prpf6 (Mmu)
Genes: Prpf6 (Mmu)
Symbol: Prpf6tm1(KOMP)Vlcg

Prpf6tm1.1(KOMP)Vlcg/Prpf6tm1.1(KOMP)Vlcg [background:] C57BL/6N-Prpf6tm1.1(KOMP)Vlcg/J

(Mus musculus)
Model
Id: MGI:6263246
Synonyms: Not Available
Symbol: Prpf6/Prpf6 [background:] C57BL/6N-Prpf6/J (Mmu)
Genes: Prpf6 (Mmu)
Alleles: Prpf6 (Mmu)
Name: Prpf6/Prpf6 [background:] C57BL/6N-Prpf6/J

Prpf6tm1.1(KOMP)Vlcg/Prpf6+ [background:] C57BL/6N-Prpf6tm1.1(KOMP)Vlcg/J

(Mus musculus)
Model
Id: MGI:5757573
Synonyms: Not Available
Symbol: Prpf6/Prpf6<+> [background:] C57BL/6N-Prpf6/J (Mmu)
Genes: Prpf6 (Mmu)
Alleles: Prpf6 (Mmu)
Name: Prpf6/Prpf6<+> [background:] C57BL/6N-Prpf6/J

Prp6

(Drosophila melanogaster)
Gene
Name: pre-mRNA processing factor 6
Synonyms: BcDNA:LD43276, CG6841, Prp6
Source: FB:FBgn0036828
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6

prp-6

(Caenorhabditis elegans)
Gene
Name: yeast PRP (splicing factor) related 6
Synonyms: Y59A8B.6, Y59A8C.a, Y59A8B.o, CELE_Y59A8B.6
Source: WB:WBGene00013343
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human PRPF6 (pre-mRNA processing factor 6).
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6

PRP6

(Saccharomyces cerevisiae)
Gene
Name: Pre-mRNA Processing
Synonyms: RNA6, YBR055C, TSM7269
Source: SGD:S000000259
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human PRPF6 (pre-mRNA processing factor 6).
Strict Orthology Symbols: prpf6

retinitis pigmentosa 60

Disease
Source: DOID:0110411
Definition: A retinitis pigmentosa that has_material_basis_in mutation in the PRPF6 gene on chromosome 20q13.33.
Genes: Prpf6 (Mmu)...prpf6 (Dre)...prpf6.S (Xla)...Prpf6 (Rno)...prpf6 (Xtr)

RNA localization

Gene Ontology
Source: GO:0006403
Synonyms:
  • RNA localisation
  • establishment and maintenance of RNA localization
Branch: biological process
Genes: Prpf6 (Mmu)...Prpf6 (Rno)...PRPF6 (Hsa)

sa44995

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-190123-615
Genes: prpf6 (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: prpf6 (Dre)

spliceosomal tri-snRNP complex assembly

Gene Ontology
Source: GO:0000244
Synonyms:
  • assembly of spliceosomal tri-snRNP
  • assembly of spliceosomal tri-snRNP U4/U6.U5
Branch: biological process
Genes: prpf6 (Dre)...Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

U5 snRNP

Gene Ontology
Source: GO:0005682
Synonyms:
  • snRNP U5
Branch: cellular component
Genes: Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

ribonucleoprotein complex binding

Gene Ontology
Source: GO:0043021
Synonyms:
  • RNP binding
  • protein-RNA complex binding
Branch: molecular function
Genes: Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

U2-type precatalytic spliceosome

Gene Ontology
Source: GO:0071005
Synonyms:
  • GT-AG precatalytic spliceosome
  • major precatalytic spliceosome
Branch: cellular component
Genes: Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

RNA splicing, via transesterification reactions

Gene Ontology
Source: GO:0000375
Synonyms:
  • RNA splicing factor activity, transesterification mechanism
  • pre-mRNA splicing factor activity
Branch: biological process
Genes: PRPF6 (Hsa)

U4/U6 x U5 tri-snRNP complex

Gene Ontology
Source: GO:0046540
Synonyms:
  • U4/U6.U5 snRNP complex
Branch: cellular component
Genes: Prpf6 (Mmu)...PRPF6 (Hsa)...prpf6 (Dre)...Prpf6 (Rno)

nuclear androgen receptor binding

Gene Ontology
Source: GO:0050681
Synonyms:
  • AR binding
  • androgen receptor binding
Branch: molecular function
Genes: Prpf6 (Mmu)

spliceosomal complex assembly

Gene Ontology
Source: GO:0000245
Synonyms:
  • spliceosome assembly
Branch: biological process
Genes: PRPF6 (Hsa)

catalytic step 2 spliceosome

Gene Ontology
Source: GO:0071013
Synonyms:
  • mammalian spliceosomal complex C
  • mammalian spliceosomal complex C1
Branch: cellular component
Genes: prpf6 (Dre)...Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

protein-macromolecule adaptor activity

Gene Ontology
Source: GO:0030674
Synonyms:
  • protein binding, bridging
  • protein complex scaffold activity
Branch: molecular function
Genes: Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

mRNA splicing, via spliceosome

Gene Ontology
Source: GO:0000398
Synonyms:
  • mRNA splicing
  • nuclear mRNA splicing via U12-type spliceosome
Branch: biological process
Genes: prpf6 (Dre)...Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

nuclear speck

Gene Ontology
Source: GO:0016607
Synonyms:
  • nuclear speckle
  • nuclear speckles
Branch: cellular component
Genes: Prpf6 (Rno)...Prpf6 (Mmu)...PRPF6 (Hsa)

spliceosomal complex

Gene Ontology
Source: GO:0005681
Synonyms:
  • spliceosome
  • spliceosome complex
Branch: cellular component
Genes: PRPF6 (Hsa)

transcription coactivator activity

Gene Ontology
Source: GO:0003713
Synonyms:
  • RNA polymerase II transcription co-activator activity
  • RNA polymerase II transcription coactivator activity
Branch: molecular function
Genes: Prpf6 (Mmu)

RNA binding

Gene Ontology
Source: GO:0003723
Synonyms:
  • base pairing with RNA
  • poly(A) RNA binding
Branch: molecular function
Genes: Prpf6 (Mmu)...PRPF6 (Hsa)...Prpf6 (Rno)

identical protein binding

Gene Ontology
Source: GO:0042802
Synonyms:
  • isoform-specific homophilic binding
  • protein homopolymerization
Branch: molecular function
Genes: Prpf6 (Mmu)...PRPF6 (Hsa)...Prpf6 (Rno)

sa1110

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-10084
Genes: prpf6 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: prpf6 (Dre)

RNA splicing

Gene Ontology
Source: GO:0008380
Synonyms:
  • pre-mRNA splicing factor activity
Branch: biological process
Genes: PRPF6 (Hsa)

RNA processing

Gene Ontology
Source: GO:0006396
Synonyms: Not Available
Branch: biological process
Genes: prpf6 (Dre)

mRNA processing

Gene Ontology
Source: GO:0006397
Synonyms:
  • mRNA maturation
Branch: biological process
Genes: PRPF6 (Hsa)

positive regulation of transcription by RNA polymerase II

Gene Ontology
Source: GO:0045944
Synonyms:
  • activation of global transcription from RNA polymerase II promoter
  • activation of transcription from RNA polymerase II promoter
Branch: biological process
Genes: Prpf6 (Mmu)...PRPF6 (Hsa)...Prpf6 (Rno)

(GRCh38)20:63981293C>T

(Homo sapiens)
Allele/Variant
Source: rs748000228
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63981293C>T

(GRCh38)20:63983047C>T

(Homo sapiens)
Allele/Variant
Source: rs774832670
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63983047C>T

(GRCh38)20:63983192C>T

(Homo sapiens)
Allele/Variant
Source: NC_000020.11:g.63983192C>T
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63983192C>T

(GRCh38)20:63984975T>C

(Homo sapiens)
Allele/Variant
Source: rs1246773533
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63984975T>C

(GRCh38)20:63993437A>G

(Homo sapiens)
Allele/Variant
Source: rs2123001134
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63993437A>G

(GRCh38)20:63995448C>T

(Homo sapiens)
Allele/Variant
Source: NC_000020.11:g.63995448C>T
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63995448C>T

(GRCh38)20:63995499G>A

(Homo sapiens)
Allele/Variant
Source: rs2059137383
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63995499G>A

(GRCh38)20:63999032G>C

(Homo sapiens)
Allele/Variant
Source: rs780036288
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63999032G>C

(GRCh38)20:63999098G>C

(Homo sapiens)
Allele/Variant
Source: rs201487454
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63999098G>C

(GRCh38)20:64016764C>T

(Homo sapiens)
Allele/Variant
Source: rs367582115
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)20:64016764C>T

(GRCh38)20:63983032G>C

(Homo sapiens)
Allele/Variant
Source: rs370288680
Genes: PRPF6 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)20:63983032G>C