Version: 8.2.0
Date: Wed Aug 27 2025
311 results for scc-2

scc-2

(Caenorhabditis elegans)
Gene
Name: yeast SCC (mitotic condensin subunit) homolog 2
Synonyms: CELE_Y43H11AL.3, pqn-85, Y43H11AL.a, Y43H11AL.b, Y43H11AL.e, Y43H11AL.f, Y43H11AL.3
Source: WB:WBGene00004166
Biotype: protein coding gene
Symbol: scc-2 (Cel)
Symbol: scc-2
Cross References: WB:scc-2...scc-2...scc-2

NIPBL

(Homo sapiens)
Gene
Name: NIPBL cohesin loading factor
Synonyms: Nipped-B homolog (Drosophila), IDN3-B, IDN3, NIPBL, cohesin loading factor, FLJ13648, FLJ11203, SCC2 homolog, FLJ13354, FLJ12597, nipped-B-like protein, FLJ44854, delangin, CDLS, DKFZp434L1319, sister chromatid cohesion 2 homolog, Scc2, CDLS1, Nipped-B homolog
Source: HGNC:28862
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

nipbla

(Danio rerio)
Gene
Name: NIPBL cohesin loading factor a
Synonyms: si:ch73-311f13.1, si:ch211-234b6.2
Source: ZFIN:ZDB-GENE-060526-121
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

Nipbl

(Rattus norvegicus)
Gene
Name: NIPBL, cohesin loading factor
Synonyms: Nipped-B homolog (Drosophila), nipped-B-like protein, IDN3, delangin, Nipped-B homolog
Source: RGD:1306393
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

Nipbl

(Mus musculus)
Gene
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, IDN3, RIKEN cDNA 4933421G18 gene, C79399, 4921518A06Rik, RIKEN cDNA 4921518A06 gene, expressed sequence C79399
Source: MGI:1913976
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

nipblb

(Danio rerio)
Gene
Name: NIPBL cohesin loading factor b
Synonyms: nipbl, wu:fi33d08, wu:fc12g03, fc12g03
Source: ZFIN:ZDB-GENE-030131-6070
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

SCC2

(Saccharomyces cerevisiae)
Gene
Name: Sister Chromatid Cohesion
Synonyms: YDR180W
Source: SGD:S000002588
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

Nipped-B

(Drosophila melanogaster)
Gene
Name: Nipped-B
Synonyms: NIPPED-B, CG17704, Nip-B, CG40281, nipped-B, NipB, l(2)02047, NippedB, Nipped, Nipped B
Source: FB:FBgn0026401
Biotype: protein coding gene
Strict Orthology Symbols: scc-2

nipbl

(Xenopus tropicalis)
Gene
Name: NIPBL, cohesin loading factor
Synonyms: nipbl, nipbl-a, delangin, nipbl-b, NIPBL, cohesin loading factor, scc2-2, scc2
Source: Xenbase:XB-GENE-853274
Biotype: gene
Strict Orthology Symbols: scc-2

positive regulation of synaptonemal complex assembly

Gene Ontology
Source: GO:1905088
Synonyms:
  • activation of synaptonemal complex assembly
  • activation of synaptonemal complex formation
Branch: biological process
Genes: scc-2 (Cel)

SMC loading complex

Gene Ontology
Source: GO:0032116
Synonyms:
  • SCC2/SCC4 loading complex
  • chromatin loading complex
Branch: cellular component
Genes: scc-2 (Cel)

cohesin loader activity

Gene Ontology
Source: GO:0061775
Synonyms:
  • cohesin loading activity
Branch: molecular function
Genes: scc-2 (Cel)

Cornelia de Lange syndrome 1

Disease
Source: DOID:0080505
Definition: A Cornelia de Lange syndrome characterized by facial dysmorphism, including low anterior hairline, arched eyebrows, synophrys, anteverted nares, maxillary prognathism, long philtrum, thin lips, and 'carp' mouth, in association with prenatal and postnatal growth retardation, impaired intellectual development, and, in many cases, upper limb anomalies that has_material_basis_in heterozygous mutation in the NIPBL gene, which encodes a component of the cohesin complex, on chromosome 5p13.
Genes: scc-2 (Cel)

Scc2-Scc4 cohesin loading complex

Gene Ontology
Source: GO:0090694
Synonyms:
  • Mis4-Ssl3 cohesin loading complex
Branch: cellular component
Genes: scc-2 (Cel)

establishment of protein localization to chromatin

Gene Ontology
Source: GO:0071169
Synonyms:
  • establishment of protein localisation to chromatin
Branch: biological process
Genes: scc-2 (Cel)

maintenance of mitotic sister chromatid cohesion

Gene Ontology
Source: GO:0034088
Synonyms:
  • mitotic cohesion stability
Branch: biological process
Genes: scc-2 (Cel)

chromosome organization involved in meiotic cell cycle

Gene Ontology
Source: GO:0070192
Synonyms:
  • chromosome organisation involved in meiosis
  • meiotic chromosome organization
Branch: biological process
Genes: scc-2 (Cel)

establishment of mitotic sister chromatid cohesion

Gene Ontology
Source: GO:0034087
Synonyms: Not Available
Branch: biological process
Genes: scc-2 (Cel)

meiotic sister chromatid cohesion

Gene Ontology
Source: GO:0051177
Synonyms: Not Available
Branch: biological process
Genes: scc-2 (Cel)

replication-born double-strand break repair via sister chromatid exchange

Gene Ontology
Source: GO:1990414
Synonyms:
  • replication-born DSB repair by SCE
Branch: biological process
Genes: scc-2 (Cel)

chromatin looping

Gene Ontology
Source: GO:0140588
Synonyms:
  • DNA loop extrusion
  • DNA looping
Branch: biological process
Genes: scc-2 (Cel)

Cornelia de Lange syndrome

Disease
Source: DOID:11725
Definition: A syndrome that is characterized by slow growth before and after birth, intellectual disability that is usually severe to profound, skeletal abnormalities involving the arms and hands, and distinctive facial features.
Genes: scc-2 (Cel)

double-strand break repair involved in meiotic recombination

Gene Ontology
Source: GO:1990918
Synonyms: Not Available
Branch: biological process
Genes: scc-2 (Cel)

regulation of DNA damage checkpoint

Gene Ontology
Source: GO:2000001
Synonyms:
  • regulation of DNA damage response, signal transduction resulting in cell cycle arrest
Branch: biological process
Genes: scc-2 (Cel)

mitotic sister chromatid segregation

Gene Ontology
Source: GO:0000070
Synonyms:
  • mitotic chromosome segregation
  • mitotic sister-chromatid adhesion release
Branch: biological process
Genes: scc-2 (Cel)

embryo development ending in birth or egg hatching

Gene Ontology
Source: GO:0009792
Synonyms:
  • embryogenesis
Branch: biological process
Genes: scc-2 (Cel)

regulation of gene expression

Gene Ontology
Source: GO:0010468
Synonyms:
  • gene regulation
  • regulation of gene product expression
Branch: biological process
Genes: scc-2 (Cel)

cancer

Disease
Source: DOID:162
Definition: A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis.
Genes: scc-2 (Cel)

chromatin binding

Gene Ontology
Source: GO:0003682
Synonyms:
  • lamin/chromatin binding
  • microtubule/chromatin interaction
Branch: molecular function
Genes: scc-2 (Cel)

chromosome

Gene Ontology
Source: GO:0005694
Synonyms:
  • chromatid
  • interphase chromosome
Branch: cellular component
Genes: scc-2 (Cel)

tm2338

(Caenorhabditis elegans)
Allele/Variant
Source: WB:WBVar00251239
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: deletion
Molecular Consequence: coding_sequence_variant, splice_donor_variant, splice_acceptor_variant, intron_variant
Diseases: Not Available
Variant Name: Not Available
Genes: scc-2 (Cel)

(WBcel235)II:255227C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.255227C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:255227C>T
Gene Cross References: scc-2

(WBcel235)II:254609C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.254609C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:254609C>T
Gene Cross References: scc-2

(WBcel235)II:240867G>A

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.240867G>A
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)II:240867G>A
Gene Cross References: scc-2

(WBcel235)II:248825T>A

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.248825T>A
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:248825T>A
Gene Cross References: scc-2

(WBcel235)II:245849C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.245849C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)II:245849C>T
Gene Cross References: scc-2

(WBcel235)II:241436C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.241436C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:241436C>T
Gene Cross References: scc-2

(WBcel235)II:245088C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.245088C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:245088C>T
Gene Cross References: scc-2

(WBcel235)II:242521G>A

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.242521G>A
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:242521G>A
Gene Cross References: scc-2

(WBcel235)II:248045A>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.248045A>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)II:248045A>T
Gene Cross References: scc-2

(WBcel235)II:248467G>A

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.248467G>A
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)II:248467G>A
Gene Cross References: scc-2

(WBcel235)II:255244C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.255244C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:255244C>T
Gene Cross References: scc-2

(WBcel235)II:253010C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.253010C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:253010C>T
Gene Cross References: scc-2

(WBcel235)II:242634A>G

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.242634A>G
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:242634A>G
Gene Cross References: scc-2

(WBcel235)II:243170C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.243170C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:243170C>T
Gene Cross References: scc-2

(WBcel235)II:241930G>C

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.241930G>C
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:241930G>C
Gene Cross References: scc-2

(WBcel235)II:242303C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.242303C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)II:242303C>T
Gene Cross References: scc-2

(WBcel235)II:246243C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.246243C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:246243C>T
Gene Cross References: scc-2

(WBcel235)II:250733G>A

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.250733G>A
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)II:250733G>A
Gene Cross References: scc-2

(WBcel235)II:247186C>T

(Caenorhabditis elegans)
Allele/Variant
Source: NC_003280.10:g.247186C>T
Genes: scc-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)II:247186C>T
Gene Cross References: scc-2