Version: 8.0.0
Date: Tue Jan 28 2025
500 results for snx5

SNX5

(Homo sapiens)
Gene
Name: sorting nexin 5
Synonyms: sorting nexin-5, FLJ10931
Source: HGNC:14969
Biotype: protein coding gene
Symbol: SNX5 (Hsa)
Symbol: SNX5
Strict Orthology Symbols: snx5

snx5

(Danio rerio)
Gene
Name: sorting nexin 5
Synonyms: wu:fi28h04, wu:fa66c10, id:ibd5091, zgc:55769
Source: ZFIN:ZDB-GENE-040426-2857
Biotype: protein coding gene
Symbol: snx5 (Dre)
Symbol: snx5
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Strict Orthology Symbols: snx5

Snx5

(Rattus norvegicus)
Gene
Name: sorting nexin 5
Synonyms: sorting nexin-5, LOC296199
Source: RGD:1310190
Biotype: protein coding gene
Symbol: Snx5 (Rno)
Symbol: Snx5
Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5); PARTICIPATES IN retromer-mediated pathway; INTERACTS WITH
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Strict Orthology Symbols: snx5

Snx5

(Mus musculus)
Gene
Name: sorting nexin 5
Synonyms: expressed sequence AU019504, D2Ertd52e, DNA segment, Chr 2, ERATO Doi 52, expressed, AU019504, RIKEN cDNA 1810032P22 gene, 0910001N05Rik, RIKEN cDNA 0910001N05 gene, 1810032P22Rik
Source: MGI:1916428
Biotype: protein coding gene
Symbol: Snx5 (Mmu)
Symbol: Snx5
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Strict Orthology Symbols: snx5
Alleles: Snx5 (Mmu)...Snx5 (Mmu)

snx5

(Xenopus tropicalis)
Gene
Name: sorting nexin 5
Synonyms: snx5, sorting nexin 5
Source: Xenbase:XB-GENE-947018
Biotype: gene
Symbol: snx5
Symbol: snx5 (Xtr)
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Synonyms: snx5...snx5...snx5
Strict Orthology Symbols: snx5

snx5.S

(Xenopus laevis)
Gene
Name: sorting nexin 5
Synonyms: sorting nexin 5, snx5.S
Source: Xenbase:XB-GENE-947023
Biotype: gene
Symbol: snx5.S (Xla)
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Strict Orthology Symbols: snx5
Symbol: snx5.S

snx5.L

(Xenopus laevis)
Gene
Name: sorting nexin 5
Synonyms: snx5.L, sorting nexin 5
Source: Xenbase:XB-GENE-17345844
Biotype: gene
Symbol: snx5.L (Xla)
Automated Gene Synopsis: Orthologous to human SNX5 (sorting nexin 5).
Strict Orthology Symbols: snx5
Symbol: snx5.L

Snx5Gt(XA155)Byg

(Mus musculus)
Allele/Variant
Source: MGI:4123839
Genes: Snx5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Snx5 (Mmu)
Genes: Snx5 (Mmu)
Symbol: Snx5Gt(XA155)Byg

Snx5tm1a(KOMP)Wtsi

(Mus musculus)
Allele/Variant
Source: MGI:4362512
Genes: Snx5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Snx5 (Mmu)
Genes: Snx5 (Mmu)
Symbol: Snx5tm1a(KOMP)Wtsi

SNX5P2

(Homo sapiens)
Gene
Name: sorting nexin 5 pseudogene 2
Synonyms: Not Available
Source: HGNC:41513
Biotype: pseudogene
Symbol: SNX5P2 (Hsa)
Symbol: SNX5P2

SNX5P1

(Homo sapiens)
Gene
Name: sorting nexin 5 pseudogene 1
Synonyms: Not Available
Source: HGNC:41512
Biotype: pseudogene
Symbol: SNX5P1 (Hsa)
Symbol: SNX5P1

Snx5-ps1

(Rattus norvegicus)
Gene
Name: sorting nexin 5, pseudogene 1
Synonyms: LOC293740, similar to Sorting nexin-5
Source: RGD:1583864
Biotype: pseudogene
Symbol: Snx5-ps1 (Rno)
Symbol: Snx5-ps1

Snx5Gt(XA155)Byg/Snx5Gt(XA155)Byg [background:] B6.129P2-Snx5Gt(XA155)Byg

(Mus musculus)
Model
Id: MGI:5514059
Synonyms: Not Available
Symbol: Snx5/Snx5 [background:] B6.129P2-Snx5 (Mmu)
Genes: Snx5 (Mmu)
Alleles: Snx5 (Mmu)
Name: Snx5/Snx5 [background:] B6.129P2-Snx5

Snx5tm1a(KOMP)Wtsi/Snx5tm1a(KOMP)Wtsi [background:] B6JTyr;B6N-Snx5tm1a(KOMP)Wtsi/Wtsi

(Mus musculus)
Model
Id: MGI:5781759
Synonyms: Not Available
Symbol: Snx5/Snx5 [background:] B6JTyr;B6N-Snx5/Wtsi (Mmu)
Genes: Snx5 (Mmu)
Alleles: Snx5 (Mmu)
Name: Snx5/Snx5 [background:] B6JTyr;B6N-Snx5/Wtsi

snx-6

(Caenorhabditis elegans)
Gene
Name: Sorting NeXin 6
Synonyms: Y59A8B.g, CELE_Y59A8B.22, Y59A8B.22
Source: WB:WBGene00013354
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human SNX32 (sorting nexin 32); SNX5 (sorting nexin 5); and SNX6 (sorting nexin 6).
Automated Gene Synopsis: Orthologous to human SNX32 (sorting nexin 32); SNX5 (sorting nexin 5); and SNX6 (sorting nexin 6).
Strict Orthology Symbols: snx5

Snx6

(Drosophila melanogaster)
Gene
Name: Sorting nexin 6
Synonyms: DmSNX6, Dsnx6, snx6, Snx6, CG8282, SNX6
Source: FB:FBgn0032005
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human SNX32 (sorting nexin 32); SNX5 (sorting nexin 5); and SNX6 (sorting nexin 6).
Strict Orthology Symbols: snx5

macropinocytic cup

Gene Ontology
Source: GO:0070685
Synonyms:
  • crown
Branch: cellular component
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

epidermal growth factor catabolic process

Gene Ontology
Source: GO:0007174
Synonyms:
  • EGF breakdown
  • EGF catabolism
Branch: biological process
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

pinocytosis

Gene Ontology
Source: GO:0006907
Synonyms:
  • clathrin-independent pinocytosis
  • fluid-phase endocytosis
Branch: biological process
Genes: Snx5 (Rno)...Snx5 (Mmu)...snx5 (Dre)...SNX5 (Hsa)

cytoplasmic side of early endosome membrane

Gene Ontology
Source: GO:0098559
Synonyms:
  • external leaflet of early endosome membrane
  • external side of early endosome membrane
Branch: cellular component
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

tubular endosome

Gene Ontology
Source: GO:0097422
Synonyms:
  • coated tip
Branch: cellular component
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

dynactin binding

Gene Ontology
Source: GO:0034452
Synonyms: Not Available
Branch: molecular function
Genes: Snx5 (Rno)...Snx5 (Mmu)...snx5 (Dre)...SNX5 (Hsa)

zf531Tg + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-24801
Synonyms: Not Available
Genes: snx5 (Dre)
Name: zf531Tg + MO2-snx5

knu2Tg + MO1-snx5 + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-25718
Synonyms: Not Available
Genes: snx5 (Dre)
Name: knu2Tg + MO1-snx5 + MO2-snx5

mi2001Tg + MO1-dre-mir-216a + MO1-snx5 + MO2-dre-mir-216a + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-9324
Synonyms: Not Available
Genes: snx5 (Dre)
Name: mi2001Tg + MO1-dre-mir-216a + MO1-snx5 + MO2-dre-mir-216a + MO2-snx5

WT + MO1-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-17365
Synonyms: Not Available
Genes: snx5 (Dre)
Name: WT + MO1-snx5

D1 dopamine receptor binding

Gene Ontology
Source: GO:0031748
Synonyms:
  • D1 dopamine receptor ligand
  • D1A dopamine receptor binding
Branch: molecular function
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

la116Tg + MO1-snx5 + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-7596
Synonyms: Not Available
Genes: snx5 (Dre)
Name: la116Tg + MO1-snx5 + MO2-snx5

sd2Tg; y1Tg + MO1-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-6612
Synonyms: Not Available
Genes: snx5 (Dre)
Name: sd2Tg; y1Tg + MO1-snx5

mi2001Tg + MO1-snx5 + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-15685
Synonyms: Not Available
Genes: snx5 (Dre)
Name: mi2001Tg + MO1-snx5 + MO2-snx5

knu2Tg + MO1-dre-mir-216a + MO1-snx5 + MO2-dre-mir-216a + MO2-snx5

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-150901-20271
Synonyms: Not Available
Genes: snx5 (Dre)
Name: knu2Tg + MO1-dre-mir-216a + MO1-snx5 + MO2-dre-mir-216a + MO2-snx5

phosphatidylinositol-5-phosphate binding

Gene Ontology
Source: GO:0010314
Synonyms: Not Available
Branch: molecular function
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)

positive regulation of insulin receptor signaling pathway

Gene Ontology
Source: GO:0046628
Synonyms:
  • activation of insulin receptor signaling pathway
  • positive regulation of insulin receptor signalling pathway
Branch: biological process
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

Disruption of sorting nexin 5 causes respiratory failure associated with undifferentiated alveolar epithelial type I cells in mice

(Mus musculus)
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by MGI
ID: ArrayExpress:E-GEOD-37080, GEO:GSE37080
Tags: WT vs. mutant, genotype
Summary: Deletion of Snx5 leads to respiratory failure in neonatal mice. Here we analyzed the effect of depleted SNX5 in a lung. We used expression microarray to compare between wild lungs and mutant lungs at E18.5 and E18.5 after air-breathing test. Total RNA were extracted from embryonic 18.5 day (E18.5) wild and mutant mice lung. Also other total RNA samples were extracted after air-breathing test at E18.5.

retromer, tubulation complex

Gene Ontology
Source: GO:0030905
Synonyms:
  • SNX-BAR dimer
  • heterodimeric membrane-deforming retromer subcomplex
Branch: cellular component
Genes: SNX5 (Hsa)
Definition: The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6....The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.

retromer complex

Gene Ontology
Source: GO:0030904
Synonyms: Not Available
Branch: cellular component
Genes: Snx5 (Rno)...Snx5 (Mmu)...SNX5 (Hsa)
Definition: mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5...mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5

phagocytic cup

Gene Ontology
Source: GO:0001891
Synonyms: Not Available
Branch: cellular component
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

phosphatidylinositol-4-phosphate binding

Gene Ontology
Source: GO:0070273
Synonyms: Not Available
Branch: molecular function
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

negative regulation of blood pressure

Gene Ontology
Source: GO:0045776
Synonyms:
  • down regulation of blood pressure
  • down-regulation of blood pressure
Branch: biological process
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

phosphatidylinositol-3,5-bisphosphate binding

Gene Ontology
Source: GO:0080025
Synonyms:
  • PtdIns(3,5)P2 binding
Branch: molecular function
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

Hsap\SNX5UAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0338946
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\SNX5
Construct Expressed Component: SNX5 (Hsa)

gliogenesis

Gene Ontology
Source: GO:0042063
Synonyms:
  • glial cell generation
Branch: biological process
Genes: snx5 (Dre)

brush border

Gene Ontology
Source: GO:0005903
Synonyms: Not Available
Branch: cellular component
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

retrograde transport, endosome to Golgi

Gene Ontology
Source: GO:0042147
Synonyms:
  • retrograde (endosome to Golgi) transport
Branch: biological process
Genes: Snx5 (Rno)...SNX5 (Hsa)...snx5 (Dre)...Snx5 (Mmu)

ruffle

Gene Ontology
Source: GO:0001726
Synonyms:
  • membrane ruffle
Branch: cellular component
Genes: Snx5 (Rno)...SNX5 (Hsa)...Snx5 (Mmu)

phosphatidylinositol binding

Gene Ontology
Source: GO:0035091
Synonyms:
  • phosphoinositide binding
Branch: molecular function
Genes: SNX5 (Hsa)...snx5 (Dre)...Snx5 (Rno)...Snx5 (Mmu)

regulation of macroautophagy

Gene Ontology
Source: GO:0016241
Synonyms:
  • regulation of starvation-induced autophagy
Branch: biological process
Genes: SNX5 (Hsa)

cytoplasmic side of plasma membrane

Gene Ontology
Source: GO:0009898
Synonyms:
  • internal leaflet of plasma membrane
  • internal side of plasma membrane
Branch: cellular component
Genes: SNX5 (Hsa)...Snx5 (Rno)...Snx5 (Mmu)

blood vessel morphogenesis

Gene Ontology
Source: GO:0048514
Synonyms: Not Available
Branch: biological process
Genes: snx5 (Dre)

hemopoiesis

Gene Ontology
Source: GO:0030097
Synonyms:
  • blood cell biosynthesis
  • blood cell formation
Branch: biological process
Genes: snx5 (Dre)