Version: 8.1.0
Date: Fri Apr 18 2025
128 results for spd-2

spd-2

(Caenorhabditis elegans)
Gene
Name: SPindle Defective 2
Synonyms: F32H2.3, CELE_F32H2.3
Source: WB:WBGene00004953
Biotype: protein coding gene
Symbol: spd-2 (Cel)
Symbol: spd-2
Gene Synopsis: spd-2 encodes a protein with three predicted coiled-coil domains; SPD-2 activity is essential for centrosome...hence for proper mitotic spindle assembly; in regulating the early steps of centrosome maturation, SPD...the Aurora-A kinase AIR-1, and the cytoplasmic dynein DHC-1; in regulating centrosome duplication, SPD...-2 likely acts together with the ZYG-1 kinase; in both processes, SPD-2 may function to recruit centrosomal...and microtubule-nucleating gamma-tubulin complexes to the developing centrosome; within centrosomes, SPD
Cross References: spd-2...WB:spd-2...spd-2

spd-2

(Drosophila melanogaster)
Gene
Name: spindle defective 2
Synonyms: BcDNA:LD24702, dspd-2, DSpd-2, dSpd2, DSPD-2, DSpd2, Spd-2, Cep192, Spd2, SPD2, anon-73Ba, CG17286, Dspd-2, CEP192, Dspd2, SPD-2, CG17286-PA, D-SPD2, spd2, D-Spd2
Source: FB:FBgn0027500
Biotype: protein coding gene
Symbol: spd-2 (Dme)
Symbol: spd-2
Synonyms: Spd-2...SPD-2...Spd-2...SPD-2...Spd-2...SPD-2
Alleles: spd-2 (Dme)...spd-2 (Dme)...spd-2 (Dme)...spd-2 (Dme)

spd-2Ubi.cWa

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0399590
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi.cWa
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi.cWa
Constructs: Ubq-Spd-2

spd-2Cdk20A.Ubi

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0399592
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Cdk20A.Ubi
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Cdk20A.Ubi

spd-2UAS.mRFP1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0364086
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2UAS.mRFP1
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2UAS.mRFP1

spd-2Ubi.DsRed(Unk)

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0299651
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi.DsRed(Unk)
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi.DsRed(Unk)
Constructs: P{Ubi-RFP-spd-2}

spd-2ALL.Ubi.mCherry

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356218
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2ALL.Ubi.mCherry
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2ALL.Ubi.mCherry
Constructs: Ubq-Spd-2[ALL]-mCherry...Ubq-Spd-2ALL-mCherry

spd-2Ubi-p63E.mRFP1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0387463
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi-p63E.mRFP1
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi-p63E.mRFP1

spd-2Cdk20A.Ubi.mNeonGreen

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0399593
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Cdk20A.Ubi.mNeonGreen
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Cdk20A.Ubi.mNeonGreen

spd-2mNeonGreen

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0399375
Genes: spd-2 (Dme)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Gene Synonyms: Spd-2...SPD-2
Genes: spd-2 (Dme)
Name: spd-2mNeonGreen
Symbol: spd-2mNeonGreen

spd-2DE.UAS.mRFP1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0364087
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2DE.UAS.mRFP1
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2DE.UAS.mRFP1

spd-2CONS.Ubi.GFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356216
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2CONS.Ubi.GFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2CONS.Ubi.GFP
Constructs: Ubq-Spd-2CONS-GFP...Ubq-Spd-2[CONS]-GFP

spd-2ALL.Ubi.mKate2

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356219
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2ALL.Ubi.mKate2
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2ALL.Ubi.mKate2

spd-2::Dwil\spd-2AA-tail.UASp.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393143
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2::Dwil\spd-2A (Dme)
Name: spd-2::Dwil\spd-2AA-tail.UASp.EGFP
Symbol: spd-2::Dwil\spd-2AA-tail.UASp.EGFP
Constructs: UAS-Spd-2A-tail...P{UASp-spd-2::Dwil-spd-2A.A-tail.EGFP}...UAS-Spd-2[A-tail]

spd-2Δtail.UASp.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393136
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2<Δtail.UASp.EGFP> (Dme)
Name: spd-2Δtail.UASp.EGFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Δtail.UASp.EGFP
Constructs: UAS-Spd-2Δtail...UAS-Spd-2[Deltatail]

spd-2UASp.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393135
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2UASp.EGFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2UASp.EGFP
Constructs: UAS-Spd-2

spd-2::Dwil\spd-2Amel-tail.UASp.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393142
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2::Dwil\spd-2A (Dme)
Name: spd-2::Dwil\spd-2Amel-tail.UASp.EGFP
Symbol: spd-2::Dwil\spd-2Amel-tail.UASp.EGFP
Constructs: P{UASp-spd-2::Dwil-spd-2A.mel-tail.EGFP}

spd-2GD9532

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0213228
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Construct Knockdown Component: spd-2 (Dme)
Name: spd-2GD9532
Symbol: spd-2GD9532

spd-2fTRG01073.sfGFP-TVPTBF

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0339559
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2fTRG01073.sfGFP-TVPTBF
Construct Expressed Component: spd-2 (Dme)
Construct Regulatory Region: spd-2 (Dme)
Symbol: spd-2fTRG01073.sfGFP-TVPTBF

spd-2CONS.Ubi.mCherry

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356215
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2CONS.Ubi.mCherry
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2CONS.Ubi.mCherry
Constructs: Ubq-Spd-2CONS-mCherry...Ubq-Spd-2[CONS]-mCherry

spd-2AA.UAS.mRFP1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0364088
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2AA.UAS.mRFP1
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2AA.UAS.mRFP1

spd-2Ubi.GFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0240485
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi.GFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi.GFP

spd-2DK.Ubi-p63E.mRFP1

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0387464
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2DK.Ubi-p63E.mRFP1
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2DK.Ubi-p63E.mRFP1

spd-2KK110116

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0236658
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Construct Knockdown Component: spd-2 (Dme)
Name: spd-2KK110116
Symbol: spd-2KK110116

spd-2CONS.Ubi.mKate2

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356220
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2CONS.Ubi.mKate2
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2CONS.Ubi.mKate2

spd-2CT.Ubi.mKate2

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356223
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2CT.Ubi.mKate2
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2CT.Ubi.mKate2

spd-2NT.Ubi.mKate2

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356222
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2NT.Ubi.mKate2
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2NT.Ubi.mKate2

spd-2AA.Ubi.mKate2

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356221
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2AA.Ubi.mKate2
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2AA.Ubi.mKate2

spd-2ALL.Ubi.GFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356217
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2ALL.Ubi.GFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2ALL.Ubi.GFP
Constructs: Ubq-Spd-2ALL-GFP...Ubq-Spd-2[ALL]-GFP

spd-2Ubi.mCherry

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356214
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi.mCherry
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi.mCherry

spd-211A.Ubi.GFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0356213
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2<11A.Ubi.GFP> (Dme)
Name: spd-211A.Ubi.GFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-211A.Ubi.GFP
Constructs: Ubq-Spd-211A-GFP...Ubq-Spd-2[11A]-GFP

spd-2Ubi.mNeonGreen

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0399591
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2Ubi.mNeonGreen
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2Ubi.mNeonGreen

spd-2UASp.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0390943
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2UASp.Tag:HA
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2UASp.Tag:HA

spd-2DK.UAS.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0390942
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2DK.UAS.EGFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2DK.UAS.EGFP

spd-2UAS.EGFP

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0390941
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2UAS.EGFP
Construct Expressed Component: spd-2 (Dme)
Symbol: spd-2UAS.EGFP

spd-2GD14889

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0201820
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Construct Knockdown Component: spd-2 (Dme)
Name: spd-2GD14889
Symbol: spd-2GD14889

spd-2GFP,Tag:MYC

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0393134
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Name: spd-2GFP,Tag:MYC
Construct Expressed Component: spd-2 (Dme)
Construct Regulatory Region: spd-2 (Dme)
Symbol: spd-2GFP,Tag:MYC
Constructs: mel(p)-Spd-2

spd-2z3-5711

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0240470
Genes: spd-2 (Dme)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Gene Synonyms: Spd-2...SPD-2
Genes: spd-2 (Dme)
Name: spd-2z3-5711
Symbol: spd-2z3-5711

spd-2G20143

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0240486
Genes: spd-2 (Dme)
Synonyms: Not Available
Variant Type: insertion
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Gene Synonyms: Spd-2...SPD-2
Genes: spd-2 (Dme)
Name: spd-2G20143
Symbol: spd-2G20143

spd-2z3-3316

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0240471
Genes: spd-2 (Dme)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: spd-2 (Dme)
Gene Synonyms: Spd-2...SPD-2
Genes: spd-2 (Dme)
Name: spd-2z3-3316
Symbol: spd-2z3-3316

cep192

(Danio rerio)
Gene
Name: centrosomal protein 192
Synonyms: si:rp71-15i12.1, si:ch73-309n4.1
Source: ZFIN:ZDB-GENE-100922-163
Biotype: protein coding gene
Strict Orthology Symbols: spd-2

CEP192

(Homo sapiens)
Gene
Name: centrosomal protein 192
Synonyms: cep192/SPD-2, protein phosphatase 1, regulatory subunit 62, PPP1R62, centrosomal protein 192kDa, centrosomal protein of 192 kDa
Source: HGNC:25515
Biotype: protein coding gene
Synonyms: cep192/SPD-2

cep192

(Xenopus tropicalis)
Gene
Name: centrosomal protein 192kDa
Synonyms: centrosomal protein 192kDa, cep192
Source: Xenbase:XB-GENE-5880666
Biotype: gene
Strict Orthology Symbols: spd-2

or1089

(Caenorhabditis elegans)
Allele/Variant
Source: WB:WBVar00601055
Genes: spd-2 (Cel)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: spd-2 (Cel)

WH163

(Caenorhabditis elegans)
Model
Id: WB:WBStrain00040367
Synonyms: Not Available
Genes: spd-2 (Cel)

sperm aster formation

Gene Ontology
Source: GO:0035044
Synonyms: Not Available
Branch: biological process
Genes: spd-2 (Dme)

ADP-ribose diphosphatase activity

Gene Ontology
Source: GO:0047631
Synonyms:
  • ADP-ribose phosphohydrolase activity
  • ADP-ribose pyrophosphatase activity
Branch: molecular function
Genes: spd-2 (Dme)

pericentriolar material

Gene Ontology
Source: GO:0000242
Synonyms: Not Available
Branch: cellular component
Genes: spd-2 (Cel)...spd-2 (Dme)

astral microtubule organization

Gene Ontology
Source: GO:0030953
Synonyms:
  • astral microtubule organisation
  • astral microtubule organization and biogenesis
Branch: biological process
Genes: spd-2 (Dme)

sas-7

(Caenorhabditis elegans)
Gene
Name: Spindle ASsembly abnormal 7
Synonyms: T07C4.10, CELE_T07C4.10
Source: WB:WBGene00011562
Biotype: protein coding gene
Gene Synopsis: sas-7 encodes a predicted coiled-coil protein and centriole component that interacts with SPD-2 and regulates