Version: 8.1.0Date: Fri Apr 18 2025
Category
sptl-2
(Caenorhabditis elegans)Gene
Name: Serine Palmitoyl Transferase famiLy 2
Synonyms: CELE_F43H9.2, F43H9.2
Source: WB:WBGene00018398
Biotype: protein coding gene
Symbol: sptl-2 (Cel)
Symbol: sptl-2
Cross References: sptl-2...WB:sptl-2...sptl-2
SPTLC2
(Homo sapiens)Gene
Name: serine palmitoyltransferase long chain base subunit 2
Synonyms: long chain base biosynthesis protein 2, serine palmitoyltransferase 2, serine palmitoyltransferase, subunit II, LCB2, HSN1C, long chain base biosynthesis protein 2a, serine palmitoyltransferase, long chain base subunit 2, NSAN1C, KIAA0526, LCB 2, LCB2A, hLCB2a, SPT2, SPT 2, serine-palmitoyl-CoA transferase 2
Source: HGNC:11278
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
SPTLC3
(Homo sapiens)Gene
Name: serine palmitoyltransferase long chain base subunit 3
Synonyms: serine palmitoyltransferase 3, long chain base biosynthesis protein 3, dJ718P11.1, SPTLC2L, C20orf38, serine palmitoyltransferase, long chain base subunit 3, long chain base biosynthesis protein 2b, LCB3, LCB 3, dJ718P11, LCB2B, FLJ11112, hLCB2b, SPT3, serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2), SPT 3, serine-palmitoyl-CoA transferase 3, FLJ90790
Source: HGNC:16253
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
sptlc3
(Danio rerio)Gene
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: si:dkey-246k9.1
Source: ZFIN:ZDB-GENE-041210-281
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
LCB2
(Saccharomyces cerevisiae)Gene
Name: Long-Chain Base
Synonyms: SCS1, TSC1, YDR062W
Source: SGD:S000002469
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
sptlc2a
(Danio rerio)Gene
Name: serine palmitoyltransferase, long chain base subunit 2a
Synonyms: sptlc2, zgc:110661
Source: ZFIN:ZDB-GENE-050522-23
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
lace
(Drosophila melanogaster)Gene
Name: lace
Synonyms: l35Dc, SPT-II, CG4162, Serine palmitoyltransferase subunit II, serine palmitoyl-transferase, sphingosine palmitoyl transferase, l(2)35Dc, Lace, SPTLC2, SPT, dSpt2, BG:DS01845.3, anon-EST:Posey289, l(2)br36, Spt2, br36
Source: FB:FBgn0002524
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
Sptlc2
(Mus musculus)Gene
Name: serine palmitoyltransferase, long chain base subunit 2
Synonyms: LCB 2, LCB2, Pomt2, AI173915, expressed sequence AI173915, Spt2, SPT 2
Source: MGI:108074
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
sptlc2b
(Danio rerio)Gene
Name: serine palmitoyltransferase, long chain base subunit 2b
Synonyms: zgc:175221
Source: ZFIN:ZDB-GENE-080305-8
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
Sptlc2
(Rattus norvegicus)Gene
Name: serine palmitoyltransferase, long chain base subunit 2
Synonyms: long chain base biosynthesis protein 2, serine palmitoyltransferase 2, LCB 2, Pomt2, LOC366697, MGC124851, protein-O-mannosyltransferase 2, SPT 2, serine-palmitoyl-CoA transferase 2
Source: RGD:1305447
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
Sptlc3
(Mus musculus)Gene
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: RIKEN cDNA C130053K05 gene, C130053K05Rik, RGD1310030
Source: MGI:2444678
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
Sptlc3
(Rattus norvegicus)Gene
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: serine palmitoyltransferase 3, similar to dJ718P11.1.1 (novel class II aminotransferase similar to serine palmotyltransferase (isoform 1)), similar to RIKEN cDNA C130053K05 gene, LOC296188, RGD1310030
Source: RGD:1310030
Biotype: protein coding gene
Strict Orthology Symbols: sptl-2
sptlc2
(Xenopus tropicalis)Gene
Name: serine palmitoyltransferase, long chain base subunit 2
Synonyms: sptlc2, serine palmitoyltransferase, long chain base subunit 2
Source: Xenbase:XB-GENE-946143
Biotype: gene
Strict Orthology Symbols: sptl-2
Source: DOID:0070157
Definition: A hereditary sensory and autonomic neuropathy type 1 that has_material_basis_in heterozygous mutation in the SPTLC2 gene on chromosome 14q24.
Genes: sptl-2 (Cel)
sptlc3
(Xenopus tropicalis)Gene
Name: serine palmitoyltransferase, long chain base subunit 3
Synonyms: sptlc3, serine palmitoyltransferase, long chain base subunit 3
Source: Xenbase:XB-GENE-5791607
Biotype: gene
Strict Orthology Symbols: sptl-2
Source: DOID:0070162
Definition: A hereditary sensory neuropathy characterized by slowly progressing, prominent, predominantly distal sensory loss and autonomic disturbances with juvenile or adult onset and autosomal dominant inheritance.
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0004758
Synonyms:
- 3-oxosphinganine synthetase activity
- SPT
Branch: molecular function
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0017059
Synonyms:
- SPOTS complex
- SPT
Branch: cellular component
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0046512
Synonyms:
- sphingosine anabolism
- sphingosine biosynthesis
Branch: biological process
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0046513
Synonyms:
- ceramide anabolism
- ceramide biosynthesis
Branch: biological process
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0006665
Synonyms:
- sphingolipid metabolism
Branch: biological process
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0009058
Synonyms:
- anabolism
- biosynthesis
Branch: biological process
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0030170
Synonyms: Not Available
Branch: molecular function
Genes: sptl-2 (Cel)
Gene Ontology
Source: GO:0016746
Synonyms:
- transferase activity, transferring acyl groups
Branch: molecular function
Genes: sptl-2 (Cel)
Disease
Source: DOID:8893
Definition: A skin disease that is characterized by patches of thick red skin and silvery scales.
Genes: sptl-2 (Cel)
(WBcel235)V:8020825C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020825C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020825C>T
Gene Cross References: sptl-2
(WBcel235)V:8019711C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8019711C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8019711C>T
Gene Cross References: sptl-2
(WBcel235)V:8020850G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020850G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020850G>A
Gene Cross References: sptl-2
(WBcel235)V:8021030A>C
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8021030A>C
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8021030A>C
Gene Cross References: sptl-2
(WBcel235)V:8020116G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020116G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020116G>A
Gene Cross References: sptl-2
(WBcel235)V:8018306G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8018306G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8018306G>A
Gene Cross References: sptl-2
(WBcel235)V:8020726C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020726C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020726C>T
Gene Cross References: sptl-2
(WBcel235)V:8018582T>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8018582T>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8018582T>A
Gene Cross References: sptl-2
(WBcel235)V:8020906C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020906C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020906C>T
Gene Cross References: sptl-2
(WBcel235)V:8021177G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8021177G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8021177G>A
Gene Cross References: sptl-2
(WBcel235)V:8020492C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020492C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020492C>T
Gene Cross References: sptl-2
(WBcel235)V:8018502A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8018502A>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8018502A>T
Gene Cross References: sptl-2
(WBcel235)V:8018983G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8018983G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8018983G>A
Gene Cross References: sptl-2
(WBcel235)V:8019602G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8019602G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8019602G>A
Gene Cross References: sptl-2
(WBcel235)V:8020396C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020396C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020396C>T
Gene Cross References: sptl-2
(WBcel235)V:8017638G>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8017638G>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8017638G>T
Gene Cross References: sptl-2
(WBcel235)V:8017719G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8017719G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8017719G>A
Gene Cross References: sptl-2
(WBcel235)V:8018722G>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8018722G>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8018722G>T
Gene Cross References: sptl-2
(WBcel235)V:8021608A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8021608A>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8021608A>T
Gene Cross References: sptl-2
(WBcel235)V:8021646C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8021646C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8021646C>T
Gene Cross References: sptl-2
(WBcel235)V:8017330G>A
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8017330G>A
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8017330G>A
Gene Cross References: sptl-2
(WBcel235)V:8019626C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8019626C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8019626C>T
Gene Cross References: sptl-2
(WBcel235)V:8021239A>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8021239A>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8021239A>T
Gene Cross References: sptl-2
(WBcel235)V:8017354C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8017354C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8017354C>T
Gene Cross References: sptl-2
(WBcel235)V:8020587C>T
(Caenorhabditis elegans)Allele/Variant
Source: NC_003283.11:g.8020587C>T
Genes: sptl-2 (Cel)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (WBcel235)V:8020587C>T
Gene Cross References: sptl-2