Version: 8.0.0
Date: Tue Jan 28 2025
795 results for strap

Strap

(Rattus norvegicus)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: LOC297699, UNR-interacting protein, LOC100910575, serine-threonine kinase receptor-associated protein, serine-threonine kinase receptor-associated protein-like
Source: RGD:1311114
Biotype: protein coding gene
Symbol: Strap (Rno)
Symbol: Strap
Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein); PARTICIPATES IN transforming
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap

STRAP

(Homo sapiens)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: MAWD, MAPK activator with WD repeats, UNRIP, mitogen-activated protein kinase activator with WD repeats, unr-interacting protein, MAP activator with WD repeats, PT-WD, serine-threonine kinase receptor-associated protein, WD-40 repeat protein PT-WD
Source: HGNC:30796
Biotype: protein coding gene
Symbol: STRAP (Hsa)
Symbol: STRAP
Strict Orthology Symbols: strap

Strap

(Mus musculus)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: C78091, Unrip, expressed sequence AW557906, EST C78091, C79202, expressed sequence C79202, AW557906
Source: MGI:1329037
Biotype: protein coding gene
Symbol: Strap (Mmu)
Symbol: Strap
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap
Alleles: Strap (Mmu)...Strap (Mmu)...Strap (Mmu)...Strap (Mmu)...Strap (Mmu)

strap

(Danio rerio)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: zgc:56677, zgc:77604
Source: ZFIN:ZDB-GENE-040426-1110
Biotype: protein coding gene
Symbol: strap (Dre)
Symbol: strap
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap

strap

(Xenopus tropicalis)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: mawd, unrip, pt-wd, strap, serine/threonine kinase receptor associated protein
Source: Xenbase:XB-GENE-996947
Biotype: gene
Symbol: strap
Symbol: strap (Xtr)
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Synonyms: strap...strap...strap
Strict Orthology Symbols: strap

strap.L

(Xenopus laevis)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: mawd, unrip, pt-wd, strap.L, serine/threonine kinase receptor associated protein
Source: Xenbase:XB-GENE-996950
Biotype: gene
Symbol: strap.L (Xla)
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap
Symbol: strap.L

strap.S

(Xenopus laevis)
Gene
Name: serine/threonine kinase receptor associated protein
Synonyms: mawd, unrip, strap.S, pt-wd, serine/threonine kinase receptor associated protein
Source: Xenbase:XB-GENE-17338920
Biotype: gene
Symbol: strap.S (Xla)
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap
Symbol: strap.S

StrapGt(ROSA)71Sor

(Mus musculus)
Allele/Variant
Source: MGI:3526891
Genes: Strap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Strap (Mmu)
Genes: Strap (Mmu)
Symbol: StrapGt(ROSA)71Sor

Strapem2Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7306955
Genes: Strap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Strap (Mmu)
Genes: Strap (Mmu)
Symbol: Strapem2Gpt

Strapem1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7306954
Genes: Strap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Strap (Mmu)
Genes: Strap (Mmu)
Symbol: Strapem1Gpt

Strapem1Pkda

(Mus musculus)
Allele/Variant
Source: MGI:6257855
Genes: Strap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Strap (Mmu)
Genes: Strap (Mmu)
Symbol: Strapem1Pkda

Strapem2Pkda

(Mus musculus)
Allele/Variant
Source: MGI:7432303
Genes: Strap (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Strap (Mmu)
Genes: Strap (Mmu)
Symbol: Strapem2Pkda

Strapem1Pkda/Strap+ [background:] involves: C57BL/6

(Mus musculus)
Model
Id: MGI:6257857
Synonyms: Not Available
Symbol: Strap/Strap<+> [background:] involves: C57BL/6 (Mmu)
Genes: Strap (Mmu)
Alleles: Strap (Mmu)
Name: Strap/Strap<+> [background:] involves: C57BL/6

StrapGt(ROSA)71Sor/StrapGt(ROSA)71Sor [background:] involves: 129S4/SvJaeSor

(Mus musculus)
Model
Id: MGI:3527250
Synonyms: Not Available
Symbol: Strap/Strap [background:] involves: 129S4/SvJaeSor (Mmu)
Genes: Strap (Mmu)
Alleles: Strap (Mmu)
Name: Strap/Strap [background:] involves: 129S4/SvJaeSor

straphg113/hg113

(Danio rerio)
Model
Id: ZFIN:ZDB-FISH-210621-14
Synonyms: Not Available
Symbol: strap (Dre)
Genes: strap (Dre)
Name: strap

Ttc5

(Rattus norvegicus)
Gene
Name: tetratricopeptide repeat domain 5
Synonyms: stress-responsive activator of p300, LOC305837, TPR repeat protein 5, tetratricopeptide repeat protein 5, MGC108914, strap
Source: RGD:1311284
Biotype: protein coding gene
Synonyms: strap...strap...strap

wmd

(Drosophila melanogaster)
Gene
Name: wing morphogenesis defect
Synonyms: Unrip, pter, pterodactyl, CG3957, CG3957/wmd, Wing morphogenesis defect, WMD
Source: FB:FBgn0034876
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human STRAP (serine/threonine kinase receptor associated protein).
Strict Orthology Symbols: strap

TTC5

(Homo sapiens)
Gene
Name: tetratricopeptide repeat domain 5
Synonyms: stress-responsive activator of p300, TPR repeat protein 5, Strap, tetratricopeptide repeat protein 5, NEDCAFD
Source: HGNC:19274
Biotype: protein coding gene
Synonyms: Strap...Strap

SRFBP1

(Homo sapiens)
Gene
Name: serum response factor binding protein 1
Synonyms: serum response factor-binding protein 1, FLJ25286, P49, BUD22, BUD22 homolog, STRAP, SRF-dependent transcription regulation associated protein, p49/STRAP, SRF-dependent transcription regulation-associated protein, Rlb1
Source: HGNC:26333
Biotype: protein coding gene
Synonyms: STRAP...STRAP

large cell carcinoma

Disease
Source: DOID:4552
Definition: A carcinoma that is composed of large, monotonous rounded or overtly polygonal-shaped cells with abundant cytoplasm.
Genes: strap (Dre)...strap.S (Xla)...Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

squamous cell neoplasm

Disease
Source: DOID:3168
Definition: A cell type benign neoplasm composed_of epithelial cells located_in the ectodermal or endodermal cells linking body cavities.
Genes: STRAP (Hsa)...strap (Dre)...Strap (Rno)...Strap (Mmu)...strap (Xtr)

U2 snRNP binding

Gene Ontology
Source: GO:1990447
Synonyms: Not Available
Branch: molecular function
Genes: STRAP (Hsa)...Strap (Rno)...Strap (Mmu)

SMN complex

Gene Ontology
Source: GO:0032797
Synonyms:
  • SMN core complex
  • survival motor neuron complex
Branch: cellular component
Genes: Strap (Rno)...strap (Dre)...STRAP (Hsa)...Strap (Mmu)

hg113

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-190402-9
Genes: strap (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: strap (Dre)

protein-RNA complex assembly

Gene Ontology
Source: GO:0022618
Synonyms:
  • RNA-protein complex assembly
  • RNP complex assembly
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

adenocarcinoma

Disease
Source: DOID:299
Definition: A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue.
Genes: Strap (Rno)...strap.L (Xla)...strap.S (Xla)...STRAP (Hsa)...strap (Xtr)

maintenance of gastrointestinal epithelium

Gene Ontology
Source: GO:0030277
Synonyms: Not Available
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

lung carcinoma

Disease
Source: DOID:3905
Definition: A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis.
Genes: Strap (Rno)...strap.L (Xla)...strap.S (Xla)...STRAP (Hsa)...strap (Xtr)

anatomical structure development

Gene Ontology
Source: GO:0048856
Synonyms:
  • development of an anatomical structure
Branch: biological process
Genes: Strap (Mmu)

Next generation sequencing facilitates quantitative analysis of STRAP-dependent alternative splicing events

(Mus musculus)
HTP Dataset Index
High-Throughput (HTP) Dataset Index metadata provided by MGI
ID: ArrayExpress:GSE131471
Tags: baseline, developmental stage
Summary: We report the application of next generation sequencing for evaluating alternative splicing (AS) events on lineage-committed WT and Strap-KO embryoid body (EB) cells. We also analyzed AS during mouse embryo development using RNA-seq data. Of all STRAP-regulated AS, exon-skipping events were the most frequent ones with significant changes in 49% (240 out of 489) cases. Retained introns were also overrepresented (20%, 97 out of 489) as compared to other types of AS STRAP appears to function in promoting both exon inclusion and skipping at different exons. GO function revealed STRAP-regulated AS events involve in protein catabolism, molecular binding and cell motility. More specifically, they included neuronal migration and development. Together, these analyses uncovered the previous unknown role of STRAP involved in the substantial transcriptional diversity at the exon level in certain development stage. Our study also represents the first detailed analysis of AS events in the mouse early organogenesis with biologic replicates, generated by RNA-seq technology. Examination of STRAP- and development-regulated AS events, respectively.
Symbol: Next generation sequencing facilitates quantitative analysis of STRAP-dependent alternative splicing

SMN-Sm protein complex

Gene Ontology
Source: GO:0034719
Synonyms:
  • SMN-containing protein complex
Branch: cellular component
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

alternative mRNA splicing, via spliceosome

Gene Ontology
Source: GO:0000380
Synonyms:
  • alternative nuclear mRNA splicing, via spliceosome
  • splice site selection
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

spliceosomal snRNP assembly

Gene Ontology
Source: GO:0000387
Synonyms:
  • spliceosomal snRNP biogenesis
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...strap (Dre)...Strap (Mmu)

Hsap\STRAPUAS.Tag:HA

(Drosophila melanogaster)
Allele/Variant
Source: FB:FBal0340003
Genes: Not Available
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Hsap\STRAP
Construct Expressed Component: STRAP (Hsa)

Gemin6-Gemin7-unrip complex

Gene Ontology
Source: GO:0034717
Synonyms: Not Available
Branch: cellular component
Definition: A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a

colorectal carcinoma

Disease
Source: DOID:0080199
Definition: A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa.
Genes: strap (Xtr)...Strap (Rno)...STRAP (Hsa)...Strap (Mmu)...strap (Dre)

negative regulation of transforming growth factor beta receptor signaling pathway

Gene Ontology
Source: GO:0030512
Synonyms:
  • down regulation of transforming growth factor beta receptor signaling pathway
  • down-regulation of transforming growth factor beta receptor signaling pathway
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

RNA splicing

Gene Ontology
Source: GO:0008380
Synonyms:
  • pre-mRNA splicing factor activity
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...strap (Dre)

neuron differentiation

Gene Ontology
Source: GO:0030182
Synonyms: Not Available
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

mRNA binding

Gene Ontology
Source: GO:0003729
Synonyms:
  • base pairing with mRNA
Branch: molecular function
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

mRNA processing

Gene Ontology
Source: GO:0006397
Synonyms:
  • mRNA maturation
Branch: biological process
Genes: Strap (Rno)...STRAP (Hsa)...strap (Dre)

signaling receptor binding

Gene Ontology
Source: GO:0005102
Synonyms:
  • receptor binding
  • receptor ligand
Branch: molecular function
Genes: Strap (Rno)...STRAP (Hsa)...Strap (Mmu)

(GRCh38)14:20299427G>A

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.20299427G>A
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: stop_gained, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20299427G>A
Gene Synonyms: Strap

(GRCh38)14:20305896C>G

(Homo sapiens)
Allele/Variant
Source: rs34675160
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 5_prime_UTR_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20305896C>G
Gene Synonyms: Strap

(GRCh38)14:20295416G>A

(Homo sapiens)
Allele/Variant
Source: rs117492206
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20295416G>A
Gene Synonyms: Strap

(GRCh38)14:20295740G>A

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.20295740G>A
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20295740G>A
Gene Synonyms: Strap

(GRCh38)14:20301938G>A

(Homo sapiens)
Allele/Variant
Source: rs552581393
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, stop_gained, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20301938G>A
Gene Synonyms: Strap

(GRCh38)14:20295725T>C

(Homo sapiens)
Allele/Variant
Source: rs147409941
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20295725T>C
Gene Synonyms: Strap

(GRCh38)14:20296394G>A

(Homo sapiens)
Allele/Variant
Source: rs749799203
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20296394G>A
Gene Synonyms: Strap

(GRCh38)14:20289656T>C

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.20289656T>C
Genes: TTC5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)14:20289656T>C
Gene Synonyms: Strap