Version: 8.0.0Date: Tue Jan 28 2025
Category
tdp2b
(Danio rerio)Gene
Name: tyrosyl-DNA phosphodiesterase 2b
Synonyms: ttrapl, tdp2, ttrap
Source: ZFIN:ZDB-GENE-050816-1
Biotype: protein coding gene
Symbol: tdp2b (Dre)
Symbol: tdp2b
TDP2
(Homo sapiens)Gene
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: TRAF and TNF receptor associated protein, tyrosyl-RNA phosphodiesterase, TTRAP, RP1-30M3.3, ETS1-associated protein II, 5'-Tyr-DNA phosphodiesterase, ETS1-associated protein 2, MGC9099, tyr-DNA phosphodiesterase 2, MGC111021, 5'-tyrosyl-DNA phosphodiesterase, TRAF and TNF receptor-associated protein, hTDP2, VPg unlinkase, EAP2, AD022, EAPII, dJ30M3.3
Source: HGNC:17768
Biotype: protein coding gene
Strict Orthology Symbols: tdp2b
tdpt-1
(Caenorhabditis elegans)Gene
Name: Tyrosyl-DNA Phosphodiesterase Two homolog 1
Synonyms: Y63D3A.4, TDP2, CELE_Y63D3A.4
Source: WB:WBGene00013405
Biotype: protein coding gene
Strict Orthology Symbols: tdp2b
Tdp2
(Rattus norvegicus)Gene
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: 5'-Tyr-DNA phosphodiesterase, LOC498749, Traf and Tnf receptor associated protein, tyr-DNA phosphodiesterase 2, Ttrap, 5'-tyrosyl-DNA phosphodiesterase, TRAF and TNF receptor-associated protein, similar to putative TRAF and TNF receptor associated protein, MGC124734
Source: RGD:1560342
Biotype: protein coding gene
Strict Orthology Symbols: tdp2b
Tdp2
(Mus musculus)Gene
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: TRAF and TNF receptor associated protein, D13Ertd656e, Ttrap, DNA segment, Chr 13, ERATO Doi 656, expressed
Source: MGI:1860486
Biotype: protein coding gene
Strict Orthology Symbols: tdp2b
WT + MO1-tdp2b + MO2-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-10052
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO1-tdp2b + MO2-tdp2b
Gene Ontology
Source: GO:0070259
Synonyms: Not Available
Branch: molecular function
Genes: tdp2b (Dre)
WT + MO1-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-60
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO1-tdp2b
WT + MO1-smad2 + MO1-tdp2b + MO2-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-26372
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO1-smad2 + MO1-tdp2b + MO2-tdp2b
tdp2
(Xenopus tropicalis)Gene
Name: tyrosyl-DNA phosphodiesterase 2
Synonyms: eap2, tdp2, tyrosyl-DNA phosphodiesterase 2, ttrap, ad022
Source: Xenbase:XB-GENE-967013
Biotype: gene
Strict Orthology Symbols: tdp2b
WT + MO2-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-27311
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO2-tdp2b
WT + MO3-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-61
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO3-tdp2b
WT + MO1-smad3b + MO1-tdp2b + MO2-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-1891
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO1-smad3b + MO1-tdp2b + MO2-tdp2b
Gene Ontology
Source: GO:0070260
Synonyms: Not Available
Branch: molecular function
Genes: tdp2b (Dre)
la010924Tg
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-120130-481
Genes: tdp2b (Dre)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Genes: tdp2b (Dre)
WT + MO1-snai1a + MO1-tdp2b
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-150901-12801
Synonyms: Not Available
Genes: tdp2b (Dre)
Name: WT + MO1-snai1a + MO1-tdp2b
Source: DOID:0111613
Definition: An autosomal recessive cerebellar ataxia characterized by epilepsy, intellectual disability, and gait ataxia that has_material_basis_in homozygous or compound heterozygous mutation in the TDP2 gene on chromosome 6p22.3.
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0060027
Synonyms: Not Available
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0007369
Synonyms: Not Available
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0008081
Synonyms:
- phosphodiesterase
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0004518
Synonyms: Not Available
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0030145
Synonyms:
- Mn binding
- manganese binding
Branch: molecular function
Genes: tdp2b (Dre)
Source: GO:0030512
Synonyms:
- down regulation of transforming growth factor beta receptor signaling pathway
- down-regulation of transforming growth factor beta receptor signaling pathway
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0016605
Synonyms:
- ND10
- PML NB
Branch: cellular component
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0006302
Synonyms: Not Available
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0007368
Synonyms:
- determination of left/right asymmetry
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0003697
Synonyms:
- ssDNA binding
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0003824
Synonyms:
- enzyme activity
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0000287
Synonyms:
- Mg binding
- magnesium binding
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0006974
Synonyms:
- cellular DNA damage response
- cellular response to DNA damage stimulus
Branch: biological process
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0046872
Synonyms:
- heavy metal binding
- metal binding
Branch: molecular function
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0005634
Synonyms:
- cell nucleus
- horsetail nucleus
Branch: cellular component
Genes: tdp2b (Dre)
Gene Ontology
Source: GO:0006281
Synonyms: Not Available
Branch: biological process
Genes: tdp2b (Dre)
(GRCz11)19:31575550G>A
(Danio rerio)Allele/Variant
Source: ss5199321030
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31575550G>A
(GRCz11)19:31569759A>G
(Danio rerio)Allele/Variant
Source: ss5199320920
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31569759A>G
(GRCz11)19:31570339T>C
(Danio rerio)Allele/Variant
Source: ss5199320971
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31570339T>C
(GRCz11)19:31572349A>G
(Danio rerio)Allele/Variant
Source: ss5199320922
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31572349A>G
(GRCz11)19:31572588G>C
(Danio rerio)Allele/Variant
Source: ss5199320909
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31572588G>C
(GRCz11)19:31573487G>A
(Danio rerio)Allele/Variant
Source: ss5199320904
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31573487G>A
(GRCz11)19:31574026G>T
(Danio rerio)Allele/Variant
Source: ss5199320960
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31574026G>T
(GRCz11)19:31574027A>G
(Danio rerio)Allele/Variant
Source: ss5199320997
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31574027A>G
(GRCz11)19:31574272G>A
(Danio rerio)Allele/Variant
Source: ss5199320952
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31574272G>A
(GRCz11)19:31571750G>T
(Danio rerio)Allele/Variant
Source: ss5199320987
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31571750G>T
(GRCz11)19:31576055T>C
(Danio rerio)Allele/Variant
Source: ss5199321058
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: 5_prime_UTR_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31576055T>C
(GRCz11)19:31575816T>A
(Danio rerio)Allele/Variant
Source: ss5199321034
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31575816T>A
(GRCz11)19:31575989C>T
(Danio rerio)Allele/Variant
Source: ss5199321083
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31575989C>T
(GRCz11)19:31569392C>T
(Danio rerio)Allele/Variant
Source: ss5199320943
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31569392C>T
(GRCz11)19:31570344C>G
(Danio rerio)Allele/Variant
Source: ss5199320949
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31570344C>G
(GRCz11)19:31571893G>T
(Danio rerio)Allele/Variant
Source: ss5199320940
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31571893G>T
(GRCz11)19:31572582C>T
(Danio rerio)Allele/Variant
Source: ss5199320996
Genes: tdp2b (Dre), gmnn (Dre)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCz11)19:31572582C>T