Version: 8.0.0
Date: Tue Jan 28 2025
807 results for trmt5

Trmt5

(Mus musculus)
Gene
Name: TRM5 tRNA methyltransferase 5
Synonyms: RGD1306567, RIKEN cDNA 2610027O18 gene, 2610027O18Rik
Source: MGI:1923607
Biotype: protein coding gene
Symbol: Trmt5 (Mmu)
Symbol: Trmt5
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5
Alleles: Trmt5 (Mmu)...Trmt5 (Mmu)...Trmt5 (Mmu)

trmt5

(Danio rerio)
Gene
Name: tRNA methyltransferase 5
Synonyms: wu:fi28b08
Source: ZFIN:ZDB-GENE-030131-5978
Biotype: protein coding gene
Symbol: trmt5 (Dre)
Symbol: trmt5
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5

Trmt5

(Rattus norvegicus)
Gene
Name: tRNA methyltransferase 5
Synonyms: LOC362754, tRNA methyltransferase 5 homolog, TRM5 tRNA methyltransferase 5 homolog, tRNA methyltransferase 5 homolog (S. cerevisiae), RGD1306567, tRNA (guanine-N(1)-)-methyltransferase, similar to RIKEN cDNA 2610027O18, tRNA (guanine(37)-N1)-methyltransferase, TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
Source: RGD:1306567
Biotype: protein coding gene
Symbol: Trmt5 (Rno)
Symbol: Trmt5
Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5

TRMT5

(Homo sapiens)
Gene
Name: tRNA methyltransferase 5
Synonyms: TRM5, TRM5 tRNA methyltransferase 5 homolog, tRNA methyltransferase 5 homolog, M1G-methyltransferase, tRNA-N1G37 methyltransferase, tRNA [GM37] methyltransferase, PNSED, tRNA (guanine-N(1)-)-methyltransferase, COXPD26, MGC111453, tRNA (guanine(37)-N1)-methyltransferase, KIAA1393
Source: HGNC:23141
Biotype: protein coding gene
Symbol: TRMT5 (Hsa)
Symbol: TRMT5
Gene Synopsis: TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine
Strict Orthology Symbols: trmt5

trmt5

(Xenopus tropicalis)
Gene
Name: tRNA methyltransferase 5
Synonyms: trmt5, tRNA methyltransferase 5
Source: Xenbase:XB-GENE-957548
Biotype: gene
Symbol: trmt5
Symbol: trmt5 (Xtr)
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Synonyms: trmt5...trmt5...trmt5
Strict Orthology Symbols: trmt5

trmt5.L

(Xenopus laevis)
Gene
Name: tRNA methyltransferase 5
Synonyms: tRNA methyltransferase 5, trmt5.L
Source: Xenbase:XB-GENE-957552
Biotype: gene
Symbol: trmt5.L (Xla)
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5
Symbol: trmt5.L

Trmt5em1Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7307961
Genes: Trmt5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Trmt5 (Mmu)
Genes: Trmt5 (Mmu)
Symbol: Trmt5em1Gpt

Trmt5em1(IMPC)Bay

(Mus musculus)
Allele/Variant
Source: MGI:6414539
Genes: Trmt5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Trmt5 (Mmu)
Genes: Trmt5 (Mmu)
Symbol: Trmt5em1(IMPC)Bay

Trmt5em3Gpt

(Mus musculus)
Allele/Variant
Source: MGI:7307962
Genes: Trmt5 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Trmt5 (Mmu)
Genes: Trmt5 (Mmu)
Symbol: Trmt5em3Gpt

Trmt5em1(IMPC)Bay/Trmt5em1(IMPC)Bay [background:] C57BL/6N-Trmt5em1(IMPC)Bay/BayMmucd

(Mus musculus)
Model
Id: MGI:7388759
Synonyms: Not Available
Symbol: Trmt5/Trmt5 [background:] C57BL/6N-Trmt5/BayMmucd (Mmu)
Genes: Trmt5 (Mmu)
Alleles: Trmt5 (Mmu)
Name: Trmt5/Trmt5 [background:] C57BL/6N-Trmt5/BayMmucd

Trmt5em1(IMPC)Bay/Trmt5em1(IMPC)Bay [background:] C57BL/6N-Trmt5em1(IMPC)Bay/Mmmh

(Mus musculus)
Model
Id: MGI:7719977
Synonyms: Not Available
Symbol: Trmt5/Trmt5 [background:] C57BL/6N-Trmt5/Mmmh (Mmu)
Genes: Trmt5 (Mmu)
Alleles: Trmt5 (Mmu)
Name: Trmt5/Trmt5 [background:] C57BL/6N-Trmt5/Mmmh

CG32281

(Drosophila melanogaster)
Gene
Name: Not Available
Synonyms: CG12032
Source: FB:FBgn0052281
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5

TRM5

(Saccharomyces cerevisiae)
Gene
Name: tRNA Methyltransferase
Synonyms: YHR070W
Source: SGD:S000001112
Biotype: protein coding gene
Gene Synopsis: and mitochondria, and modifies both cytoplasmic and mitochondrial tRNAs; mutations in human ortholog TRMT5
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5

C53A5.17

(Caenorhabditis elegans)
Gene
Name: tRNA (guanine(37)-N(1))-methyltransferase
Synonyms: CELE_C53A5.17
Source: WB:WBGene00194707
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human TRMT5 (tRNA methyltransferase 5).
Automated Gene Synopsis: Orthologous to human TRMT5 (tRNA methyltransferase 5).
Strict Orthology Symbols: trmt5

mitochondrial tRNA methylation

Gene Ontology
Source: GO:0070901
Synonyms: Not Available
Branch: biological process
Genes: Trmt5 (Rno)...Trmt5 (Mmu)...TRMT5 (Hsa)...trmt5 (Dre)

combined oxidative phosphorylation deficiency 26

Disease
Source: DOID:0111490
Definition: A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the TRMT5 gene on chromosome 14q23.1.
Genes: trmt5 (Dre)...Trmt5 (Mmu)...Trmt5 (Rno)...trmt5 (Xtr)...TRMT5 (Hsa)

mitochondrial complex III deficiency

Disease
Source: DOID:0111139
Definition: A mitochondrial metabolism disease characterized by impaired function of one or more of the proteins making up the mitochondrial respiratory chain complex III.
Genes: Trmt5 (Rno)...trmt5 (Dre)...Trmt5 (Mmu)...trmt5 (Xtr)...TRMT5 (Hsa)

tRNA (guanine(37)-N1)-methyltransferase activity

Gene Ontology
Source: GO:0052906
Synonyms:
  • tRNA (guanine(37)-N(1))-methyltransferase activity
  • tRNA (guanosine(37)-N(1))-methyltransferase activity
Branch: molecular function
Genes: trmt5 (Dre)...Trmt5 (Mmu)...Trmt5 (Rno)...TRMT5 (Hsa)

tRNA N1-guanine methylation

Gene Ontology
Source: GO:0002939
Synonyms:
  • tRNA m1-guanine biosynthesis
Branch: biological process
Genes: Trmt5 (Rno)...Trmt5 (Mmu)...TRMT5 (Hsa)...trmt5 (Dre)

lcorl

(Xenopus tropicalis)
Gene
Name: ligand dependent nuclear receptor corepressor like
Synonyms: lcorl, LOC108698049, mlr1, ligand dependent nuclear receptor corepressor like
Source: Xenbase:XB-GENE-995017
Biotype: gene
Strict Orthology Symbols: trmt5

lactic acidosis

Disease
Source: DOID:3650
Definition: A metabolic acidosis characterized by buildup of lactate.
Genes: Trmt5 (Rno)...trmt5 (Dre)...Trmt5 (Mmu)...trmt5 (Xtr)...TRMT5 (Hsa)

hypercalcemia

Disease
Source: DOID:12678
Definition: Not Available
Genes: Trmt5 (Rno)...Trmt5 (Mmu)...TRMT5 (Hsa)...trmt5 (Dre)...trmt5 (Xtr)

tRNA methyltransferase activity

Gene Ontology
Source: GO:0008175
Synonyms: Not Available
Branch: molecular function
Genes: Trmt5 (Rno)...Trmt5 (Mmu)...TRMT5 (Hsa)...trmt5 (Dre)

mitochondrial complex I deficiency

Disease
Source: DOID:0060536
Definition: A mitochondrial metabolism disease characterized by a wide range of manifestations including marked and often fatal lactic acidosis, cardiomyopathy, leukoencephalopathy, pure myopathy and hepatopathy with tubulopathy. Among the numerous clinical phenotypes observed are Leigh syndrome, Leber hereditary optic neuropathy and MELAS syndrome. It can have material basis in mutations in multiple different genes, both nuclear-encoded and mitochondrial-encoded.
Genes: TRMT5 (Hsa)...trmt5 (Xtr)...Trmt5 (Rno)...Trmt5 (Mmu)...trmt5 (Dre)

mitochondrial myopathy

Disease
Source: DOID:699
Definition: A myopathy that is characterized by mitochondrial dysfunction.
Genes: TRMT5 (Hsa)...trmt5 (Xtr)...Trmt5 (Rno)...Trmt5 (Mmu)...trmt5 (Dre)

tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity

Gene Ontology
Source: GO:0102522
Synonyms: Not Available
Branch: molecular function
Genes: trmt5 (Dre)

cytochrome-c oxidase deficiency disease

Disease
Source: DOID:3762
Definition: A mitochondrial metabolism disease that is characterized by deficiency of cytochrome c oxidase, myopathy, hepatomegaly, hypertrophic cardiomyopathy, lactic acidosis, and Leigh syndrome, and is caused by mutations related to oxidative phosphorylation.
Genes: TRMT5 (Hsa)...trmt5 (Xtr)...Trmt5 (Rno)...Trmt5 (Mmu)...trmt5 (Dre)

tRNA methylation

Gene Ontology
Source: GO:0030488
Synonyms: Not Available
Branch: biological process
Genes: TRMT5 (Hsa)...trmt5 (Dre)

hypertrophic cardiomyopathy

Disease
Source: DOID:11984
Definition: An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause.
Genes: trmt5 (Dre)...trmt5 (Xtr)...Trmt5 (Rno)...TRMT5 (Hsa)...Trmt5 (Mmu)

tRNA processing

Gene Ontology
Source: GO:0008033
Synonyms:
  • tRNA maturation
Branch: biological process
Genes: trmt5 (Dre)...TRMT5 (Hsa)

methyltransferase activity

Gene Ontology
Source: GO:0008168
Synonyms:
  • methylase
Branch: molecular function
Genes: trmt5 (Dre)...TRMT5 (Hsa)

methylation

Gene Ontology
Source: GO:0032259
Synonyms: Not Available
Branch: biological process
Genes: trmt5 (Dre)...TRMT5 (Hsa)

mitochondrial matrix

Gene Ontology
Source: GO:0005759
Synonyms:
  • mitochondrial lumen
  • mitochondrial stroma
Branch: cellular component
Genes: trmt5 (Dre)...Trmt5 (Rno)...TRMT5 (Hsa)...Trmt5 (Mmu)

sa42236

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-160601-8049
Genes: trmt5 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_acceptor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: trmt5 (Dre)

sa2689

(Danio rerio)
Allele/Variant
Source: ZFIN:ZDB-ALT-161003-13021
Genes: trmt5 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: trmt5 (Dre)

transferase activity

Gene Ontology
Source: GO:0016740
Synonyms: Not Available
Branch: molecular function
Genes: trmt5 (Dre)

(GRCh38)14:60975662A>G

(Homo sapiens)
Allele/Variant
Source: rs773375066
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975662A>G

(GRCh38)14:60975748T>C

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.60975748T>C
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975748T>C

(GRCh38)14:60977506A>T

(Homo sapiens)
Allele/Variant
Source: rs764435470
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: splice_region_variant, intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60977506A>T

(GRCh38)14:60980755A>G

(Homo sapiens)
Allele/Variant
Source: rs76464913
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: intron_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60980755A>G

(GRCh38)14:60976122C>T

(Homo sapiens)
Allele/Variant
Source: rs575587861
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60976122C>T

(GRCh38)14:60977541T>G

(Homo sapiens)
Allele/Variant
Source: rs1594926285
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60977541T>G

(GRCh38)14:60977563C>A

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.60977563C>A
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60977563C>A

(GRCh38)14:60979263C>T

(Homo sapiens)
Allele/Variant
Source: rs114005374
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60979263C>T

(GRCh38)14:60979684A>G

(Homo sapiens)
Allele/Variant
Source: rs183355161
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60979684A>G

(GRCh38)14:60979829G>A

(Homo sapiens)
Allele/Variant
Source: rs1205147646
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60979829G>A

(GRCh38)14:60975114T>C

(Homo sapiens)
Allele/Variant
Source: rs1262546391
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975114T>C

(GRCh38)14:60975853C>T

(Homo sapiens)
Allele/Variant
Source: rs146619348
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975853C>T

(GRCh38)14:60975865A>G

(Homo sapiens)
Allele/Variant
Source: rs2139640838
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975865A>G

(GRCh38)14:60975956G>A

(Homo sapiens)
Allele/Variant
Source: NC_000014.9:g.60975956G>A
Genes: TRMT5 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)14:60975956G>A