Version: 8.0.0
Date: Tue Jan 28 2025
495 results for vps4a

Vps4a

(Rattus norvegicus)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: vacuolar protein sorting protein 4a, vacuolar protein sorting 4a, vacuolar protein sorting-associated protein 4A, vacuolar protein sorting 4a (yeast), vacuolar protein sorting 4 homolog A (S. cerevisiae)
Source: RGD:628810
Biotype: protein coding gene
Symbol: Vps4a (Rno)
Symbol: Vps4a
Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A); PARTICIPATES IN autophagy pathway;
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Strict Orthology Symbols: vps4a

Vps4a

(Mus musculus)
Gene
Name: vacuolar protein sorting 4A
Synonyms: 4930589C15Rik, expressed sequence AI325971, AI325971, MGC:11698, RIKEN cDNA 4930589C15 gene, AW553189, expressed sequence AW553189
Source: MGI:1890520
Biotype: protein coding gene
Symbol: Vps4a (Mmu)
Symbol: Vps4a
Gene Synopsis: PHENOTYPE: Mouse embryonic fibroblasts from mice heterozygous for Vps4a and Vps4b null alleles exhibit
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Strict Orthology Symbols: vps4a
Alleles: Vps4a (Mmu)...Vps4a (Mmu)...Vps4a (Mmu)...Vps4a (Mmu)...Vps4a (Mmu)

VPS4A

(Homo sapiens)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: SKD2, FLJ22197, hVPS4, SKD1, SKD1A, vacuolar protein sorting factor 4A, vacuolar protein sorting 4 homolog A (S. cerevisiae), VPS4-1, vacuolar sorting protein 4, VPS4, vacuolar protein sorting-associated protein 4A, SKD1-homolog, CIMDAG
Source: HGNC:13488
Biotype: protein coding gene
Symbol: VPS4A (Hsa)
Symbol: VPS4A
Strict Orthology Symbols: vps4a

vps4a

(Danio rerio)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: zgc:153907
Source: ZFIN:ZDB-GENE-060929-388
Biotype: protein coding gene
Symbol: vps4a (Dre)
Symbol: vps4a
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Strict Orthology Symbols: vps4a

vps4a

(Xenopus tropicalis)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: vps4a, vacuolar protein sorting 4 homolog A
Source: Xenbase:XB-GENE-970546
Biotype: gene
Symbol: vps4a
Symbol: vps4a (Xtr)
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Synonyms: vps4a...vps4a...vps4a
Strict Orthology Symbols: vps4a

vps4a.S

(Xenopus laevis)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: vps4a.S, vacuolar protein sorting 4 homolog A
Source: Xenbase:XB-GENE-17341123
Biotype: gene
Symbol: vps4a.S (Xla)
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Strict Orthology Symbols: vps4a
Symbol: vps4a.S

vps4a.L

(Xenopus laevis)
Gene
Name: vacuolar protein sorting 4 homolog A
Synonyms: vacuolar protein sorting 4 homolog A, vps4a.L
Source: Xenbase:XB-GENE-970551
Biotype: gene
Symbol: vps4a.L (Xla)
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A).
Strict Orthology Symbols: vps4a
Symbol: vps4a.L

Vps4atm1.2Thkn

(Mus musculus)
Allele/Variant
Source: MGI:6459252
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4atm1.2Thkn

Vps4aGt(OST18566)Lex

(Mus musculus)
Allele/Variant
Source: MGI:3530230
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4aGt(OST18566)Lex

Vps4aem1Smoc

(Mus musculus)
Allele/Variant
Source: MGI:7626996
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4aem1Smoc

Vps4atm1.1Thkn

(Mus musculus)
Allele/Variant
Source: MGI:6459251
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4atm1.1Thkn

Vps4atm1a(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:5300810
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4atm1a(EUCOMM)Hmgu

Vps4atm1b(EUCOMM)Hmgu

(Mus musculus)
Allele/Variant
Source: MGI:5561562
Genes: Vps4a (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Vps4a (Mmu)
Genes: Vps4a (Mmu)
Symbol: Vps4atm1b(EUCOMM)Hmgu

Vps4atm1.2Thkn/Vps4a+ Vps4btm1Thkn/Vps4b+ [background:] B6.129S2(Cg)-Vps4btm1Thkn Vps4atm1.2Thkn

(Mus musculus)
Model
Id: MGI:6459272
Synonyms: Not Available
Symbol: Vps4a/Vps4a<+> Vps4b/Vps4b<+> [background:] B6.129S2(Cg)-Vps4b Vps4a
Genes: Vps4a (Mmu)
Alleles: Vps4a (Mmu)
Name: Vps4a/Vps4a<+> Vps4b/Vps4b<+> [background:] B6.129S2(Cg)-Vps4b Vps4a

Vps4atm1b(EUCOMM)Hmgu/Vps4a+ [background:] C57BL/6N-Vps4atm1b(EUCOMM)Hmgu/Bay

(Mus musculus)
Model
Id: MGI:5757880
Synonyms: Not Available
Symbol: Vps4a/Vps4a<+> [background:] C57BL/6N-Vps4a/Bay (Mmu)
Genes: Vps4a (Mmu)
Alleles: Vps4a (Mmu)
Name: Vps4a/Vps4a<+> [background:] C57BL/6N-Vps4a/Bay

Vps4atm1b(EUCOMM)Hmgu/Vps4atm1b(EUCOMM)Hmgu [background:] C57BL/6N-Vps4atm1b(EUCOMM)Hmgu/Bay

(Mus musculus)
Model
Id: MGI:5757881
Synonyms: Not Available
Symbol: Vps4a/Vps4a [background:] C57BL/6N-Vps4a/Bay (
Genes: Vps4a (Mmu)
Alleles: Vps4a (Mmu)
Name: Vps4a/Vps4a [background:] C57BL/6N-Vps4a/Bay

vps-4

(Caenorhabditis elegans)
Gene
Name: related to yeast Vacuolar Protein Sorting factor 4
Synonyms: CELE_Y34D9A.10, phi-25, Y34D9A.b, Y34D9A.10
Source: WB:WBGene00021334
Biotype: protein coding gene
Gene Synopsis: Is an ortholog of human VPS4A (vacuolar protein sorting 4 homolog A) and VPS4B (vacuolar protein sorting
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A) and VPS4B (vacuolar protein sorting
Strict Orthology Symbols: vps4a

Vps4

(Drosophila melanogaster)
Gene
Name: Vacuolar protein sorting 4
Synonyms: CG6842, BcDNA:GH02678, 3B1, bcDNA:GH02678, dvps4, Vps4B, DmBcDNA.GH02678, vacuolar protein sorting 4, Dvps4, vps4
Source: FB:FBgn0283469
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human VPS4A (vacuolar protein sorting 4 homolog A) and VPS4B (vacuolar protein sorting
Strict Orthology Symbols: vps4a

VPS4

(Saccharomyces cerevisiae)
Gene
Name: Vacuolar Protein Sorting
Synonyms: CSC1, GRD13, DID6, VPT10, YPR173C, VPL4, END13
Source: SGD:S000006377
Biotype: protein coding gene
Strict Orthology Symbols: vps4a

vesicle uncoating

Gene Ontology
Source: GO:0072319
Synonyms:
  • vesicle coat disassembly
Branch: biological process
Genes: Vps4a (Mmu)...Vps4a (Rno)...VPS4A (Hsa)

positive regulation of viral budding via host ESCRT complex

Gene Ontology
Source: GO:1903774
Synonyms:
  • activation of viral budding through the ESCRT machinery
  • activation of viral budding via host ESCRT complex
Branch: biological process
Genes: Vps4a (Mmu)...Vps4a (Rno)...VPS4A (Hsa)

late endosome to lysosome transport via multivesicular body sorting pathway

Gene Ontology
Source: GO:0061764
Synonyms: Not Available
Branch: biological process
Genes: Vps4a (Mmu)...VPS4A (Hsa)

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway

Gene Ontology
Source: GO:0090611
Synonyms: Not Available
Branch: biological process
Genes: Vps4a (Mmu)...Vps4a (Rno)...VPS4A (Hsa)

late endosomal microautophagy

Gene Ontology
Source: GO:0061738
Synonyms: Not Available
Branch: biological process
Genes: Vps4a (Mmu)...Vps4a (Rno)...VPS4A (Hsa)

mitotic cytokinesis checkpoint signaling

Gene Ontology
Source: GO:0044878
Synonyms:
  • cytokinesis after mitosis checkpoint
  • defective cytokinesis checkpoint
Branch: biological process
Genes: Vps4a (Mmu)...Vps4a (Rno)...VPS4A (Hsa)

negative regulation of cytokinesis

Gene Ontology
Source: GO:0032466
Synonyms:
  • down regulation of cytokinesis
  • down-regulation of cytokinesis
Branch: biological process
Genes: Vps4a (Mmu)...VPS4A (Hsa)...Vps4a (Rno)

viral budding from plasma membrane

Gene Ontology
Source: GO:0046761
Synonyms:
  • plasma membrane viral budding
  • plasma membrane viral budding during viral capsid envelopment
Branch: biological process
Genes: Vps4a (Mmu)...VPS4A (Hsa)...Vps4a (Rno)

positive regulation of exosomal secretion

Gene Ontology
Source: GO:1903543
Synonyms:
  • activation of exosomal protein secretion
  • activation of exosomal secretion
Branch: biological process
Genes: Vps4a (Mmu)...VPS4A (Hsa)...Vps4a (Rno)

ESCRT complex disassembly

Gene Ontology
Source: GO:1904896
Synonyms:
  • endosomal sorting complex required for transport disassembly
Branch: biological process
Genes: VPS4A (Hsa)

vacuole organization

Gene Ontology
Source: GO:0007033
Synonyms:
  • vacuolar assembly
  • vacuole biogenesis
Branch: biological process
Genes: VPS4A (Hsa)...vps4a (Dre)...Vps4a (Mmu)...Vps4a (Rno)

viral budding via host ESCRT complex

Gene Ontology
Source: GO:0039702
Synonyms:
  • host-assisted viral budding
  • viral budding through the ESCRT machinery
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

intracellular cholesterol transport

Gene Ontology
Source: GO:0032367
Synonyms: Not Available
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

multivesicular body assembly

Gene Ontology
Source: GO:0036258
Synonyms:
  • MVB biogenesis
  • MVB formation
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

ATPase complex

Gene Ontology
Source: GO:1904949
Synonyms:
  • VPS4 complex
Branch: cellular component
Genes: Vps4a (Mmu)...VPS4A (Hsa)

abscission

Gene Ontology
Source: GO:0009838
Synonyms: Not Available
Branch: biological process
Genes: Vps4a (Mmu)

vesicle budding from membrane

Gene Ontology
Source: GO:0006900
Synonyms:
  • membrane evagination
  • nonselective vesicle assembly
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

endosomal vesicle fusion

Gene Ontology
Source: GO:0034058
Synonyms:
  • endosome vesicle fusion
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

ATP-dependent protein disaggregase activity

Gene Ontology
Source: GO:0140545
Synonyms:
  • protein disaggregase activity
  • protein unfoldase activity
Branch: molecular function
Genes: VPS4A (Hsa)

Vps4b

(Mus musculus)
Gene
Name: vacuolar protein sorting 4B
Synonyms: suppressor of K+ transport defect 1, Skd1, 8030489C12Rik, RIKEN cDNA 8030489C12 gene
Source: MGI:1100499
Biotype: protein coding gene
Gene Synopsis: Mouse embryonic fibroblasts from mice heterozygous for Vps4a and Vps4b null alleles exhibit increased

midbody abscission

Gene Ontology
Source: GO:0061952
Synonyms:
  • cell separation during cytokinesis
  • cytokinetic abscission
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

ESCRT III complex disassembly

Gene Ontology
Source: GO:1904903
Synonyms: Not Available
Branch: biological process
Genes: VPS4A (Hsa)

nuclear membrane reassembly

Gene Ontology
Source: GO:0031468
Synonyms:
  • nuclear envelope reassembly
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)

actomyosin contractile ring contraction

Gene Ontology
Source: GO:0000916
Synonyms:
  • actomyosin contractile ring constriction
  • contractile ring contraction involved in cell cycle cytokinesis
Branch: biological process
Genes: VPS4A (Hsa)

protein targeting to lysosome

Gene Ontology
Source: GO:0006622
Synonyms:
  • protein-lysosome targeting
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

nucleus organization

Gene Ontology
Source: GO:0006997
Synonyms:
  • nuclear morphology
  • nuclear organisation
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

membrane fission

Gene Ontology
Source: GO:0090148
Synonyms:
  • membrane scission
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)

Flemming body

Gene Ontology
Source: GO:0090543
Synonyms:
  • Midbody ring
Branch: cellular component
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

regulation of protein localization to plasma membrane

Gene Ontology
Source: GO:1903076
Synonyms:
  • regulation of establishment of protein localisation in plasma membrane
  • regulation of establishment of protein localization in plasma membrane
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Gene Ontology
Source: GO:0043162
Synonyms:
  • ubiquitin-dependent protein breakdown via the multivesicular body pathway
  • ubiquitin-dependent protein catabolic process via the MVB pathway
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)...Vps4a (Rno)

multivesicular body sorting pathway

Gene Ontology
Source: GO:0071985
Synonyms: Not Available
Branch: biological process
Genes: VPS4A (Hsa)...Vps4a (Mmu)