Version: 8.0.0Date: Tue Jan 28 2025
Category
WARS2
(Homo sapiens)Gene
Name: tryptophanyl tRNA synthetase 2, mitochondrial
Synonyms: tryptophan--tRNA ligase, tryptophanyl-tRNA synthetase, mitochondrial, NEMMLAS, mtTrpRS, (Mt)TrpRS, PKDYS3, TrpRS, tryptophan tRNA ligase 2, mitochondrial, tryptophan--tRNA ligase, mitochondrial, tryptophan-tRNA ligase
Source: HGNC:12730
Biotype: protein coding gene
Symbol: WARS2 (Hsa)
Symbol: WARS2
Strict Orthology Symbols: wars2
wars2
(Danio rerio)Gene
Name: tryptophanyl tRNA synthetase 2, mitochondrial
Synonyms: zgc:110828
Source: ZFIN:ZDB-GENE-050306-26
Biotype: protein coding gene
Symbol: wars2 (Dre)
Symbol: wars2
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
Wars2
(Mus musculus)Gene
Name: tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms: 5730427B17Rik, TrpRS, expressed sequence AI413375, RIKEN cDNA 5730427B17 gene, AI413375, 9430020O07Rik, RIKEN cDNA 9430020O07 gene
Source: MGI:1917810
Biotype: protein coding gene
Symbol: Wars2 (Mmu)
Symbol: Wars2
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
Alleles: Wars2
Wars2
(Rattus norvegicus)Gene
Name: tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms: LOC690654, tryptophan--tRNA ligase, mitochondrial, similar to mitochondrial tryptophanyl tRNA synthetase 2
Source: RGD:1593417
Biotype: protein coding gene
Symbol: Wars2 (Rno)
Symbol: Wars2
Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial); PARTICIPATES IN tryptophan
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
wars2
(Xenopus tropicalis)Gene
Name: tryptophanyl tRNA synthetase 2, mitochondrial
Synonyms: tryptophanyl tRNA synthetase 2, mitochondrial, wars2
Source: Xenbase:XB-GENE-958813
Biotype: gene
Symbol: wars2
Symbol: wars2 (Xtr)
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Synonyms: wars2...wars2...wars2
Strict Orthology Symbols: wars2
WARS2-IT1
(Homo sapiens)Gene
Name: WARS2 intronic transcript 1
Synonyms: Not Available
Source: HGNC:41393
Biotype: ncRNA gene
Symbol: WARS2-IT1 (Hsa)
Symbol: WARS2-IT1
WARS2-AS1
(Homo sapiens)Gene
Name: WARS2 antisense RNA 1
Synonyms: Not Available
Source: HGNC:40612
Biotype: ncRNA gene
Symbol: WARS2-AS1 (Hsa)
Symbol: WARS2-AS1
wars2.L
(Xenopus laevis)Gene
Name: tryptophanyl tRNA synthetase 2, mitochondrial
Synonyms: tryptophanyl tRNA synthetase 2, mitochondrial, wars2.L
Source: Xenbase:XB-GENE-6487175
Biotype: gene
Symbol: wars2.L (Xla)
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
Symbol: wars2.L
wars2.S
(Xenopus laevis)Gene
Name: tryptophanyl tRNA synthetase 2, mitochondrial
Synonyms: tryptophanyl tRNA synthetase 2, mitochondrial, wars2.S
Source: Xenbase:XB-GENE-17339860
Biotype: gene
Symbol: wars2.S (Xla)
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
Symbol: wars2.S
Wars2em1Gpt
(Mus musculus)Allele/Variant
Source: MGI:7308565
Genes: Wars2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Wars2
Genes: Wars2 (Mmu)
Symbol: Wars2em1Gpt
Wars2tm1(KOMP)Vlcg
(Mus musculus)Allele/Variant
Source: MGI:4951215
Genes: Wars2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Wars2
Genes: Wars2 (Mmu)
Symbol: Wars2tm1(KOMP)Vlcg
Wars2em14Gpt
(Mus musculus)Allele/Variant
Source: MGI:7308564
Genes: Wars2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Wars2
Genes: Wars2 (Mmu)
Symbol: Wars2em14Gpt
Wars2tm1.1(KOMP)Vlcg
(Mus musculus)Allele/Variant
Source: MGI:5468955
Genes: Wars2 (Mmu)
Synonyms: Not Available
Variant Type: unreported
Molecular Consequence: Not Available
Diseases: Not Available
Variant Name: Not Available
Symbol: Wars2
Genes: Wars2 (Mmu)
Symbol: Wars2tm1.1(KOMP)Vlcg
WARS2P1
(Homo sapiens)Gene
Name: tryptophanyl tRNA synthetase 2 pseudogene 1
Synonyms: Not Available
Source: HGNC:45116
Biotype: pseudogene
Symbol: WARS2P1 (Hsa)
Symbol: WARS2P1
Id: MGI:5792426
Synonyms: Not Available
Symbol: Wars2/Wars2 [background:] involves: BALB/c * C3H/HeH * C57BL/6J (Mmu)
Genes: Wars2 (Mmu)
Alleles: Wars2
Name: Wars2/Wars2 [background:] involves: BALB/c * C3H/HeH * C57BL/6J
Model
Id: MGI:5759533
Synonyms: Not Available
Symbol: Wars2/Wars2<+> [background:] C57BL/6N-Wars2/J (Mmu)
Genes: Wars2 (Mmu)
Alleles: Wars2
Name: Wars2/Wars2<+> [background:] C57BL/6N-Wars2/J
Wars2tm1.1(KOMP)Vlcg/Wars2tm1.1(KOMP)Vlcg [background:] C57BL/6N-Wars2tm1.1(KOMP)Vlcg/J
(Mus musculus)Model
Id: MGI:5631679
Synonyms: Not Available
Symbol: Wars2/Wars2 [background:] C57BL/6N-Wars2/J (Mmu)
Genes: Wars2 (Mmu)
Alleles: Wars2
Name: Wars2/Wars2 [background:] C57BL/6N-Wars2/J
Wars2mpc151H
(Mus musculus)Allele/Variant
Source: MGI:5791998
Genes: Wars2 (Mmu)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_region_variant, missense_variant
Diseases: Not Available
Variant Name: Not Available
Symbol: Wars2
Genes: Wars2 (Mmu)
Symbol: Wars2mpc151H
prx-10
(Caenorhabditis elegans)Gene
Name: PeRoXisome assembly factor 10
Synonyms: CELE_C34E10.4, C34E10.4, wars-2, wrs-2
Source: WB:WBGene00006946
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
TrpRS-m
(Drosophila melanogaster)Gene
Name: Tryptophanyl-tRNA synthetase, mitochondrial
Synonyms: dmWARS2, CG7441, GH31, BEST:CK01295
Source: FB:FBgn0036763
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
MSW1
(Saccharomyces cerevisiae)Gene
Name: Mitochondrial aminoacyl-tRNA Synthetase, tryptophan (W)
Synonyms: YDR268W
Source: SGD:S000002676
Biotype: protein coding gene
Automated Gene Synopsis: Orthologous to human WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial).
Strict Orthology Symbols: wars2
Gene Ontology
Source: GO:0070183
Synonyms: Not Available
Branch: biological process
Genes: WARS2 (Hsa)...Wars2 (Mmu)...wars2 (Dre)...Wars2 (Rno)
Gene Ontology
Source: GO:0004830
Synonyms:
- L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity
- L-tryptophan-tRNATrp ligase (AMP-forming)
Branch: molecular function
Genes: wars2 (Dre)...WARS2 (Hsa)...Wars2 (Mmu)...Wars2 (Rno)
Gene Ontology
Source: GO:0006436
Synonyms: Not Available
Branch: biological process
Genes: wars2 (Dre)...WARS2 (Hsa)...Wars2 (Mmu)
Disease
Source: DOID:480
Definition: A brain disease that is characterized by a clinical syndrome of either hyperkinetic movement or hyperkinetic movement unrelated to weakness or spasticity.
Genes: WARS2 (Hsa)...Wars2 (Rno)...wars2 (Dre)...wars2 (Xtr)...Wars2 (Mmu)
bw18Tg; bw19Tg + MO1-wars2
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-171016-8
Synonyms: Not Available
Genes: wars2 (Dre)
Name: bw18Tg; bw19Tg + MO1-wars2
WT + MO1-wars2
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-171016-4
Synonyms: Not Available
Genes: wars2 (Dre)
Name: WT + MO1-wars2
bw17Tg + MO1-wars2
(Danio rerio)Model
Id: ZFIN:ZDB-FISH-171016-7
Synonyms: Not Available
Genes: wars2 (Dre)
Name: bw17Tg + MO1-wars2
SHR-Tg(EEF1A1-Wars2)Ipcv
(Rattus norvegicus)Model
Id: RGD:150429988
Synonyms: SHR-Tg(Ef1a-Wars2)Ipcv, SHR-Wars2
Name: SHR-Tg(EEF1A1-Wars2)Ipcv
Source: DOID:700
Definition: An inherited metabolic disorder that involves mitochondrial metabolism dysfunction.
Genes: WARS2 (Hsa)...Wars2 (Rno)...wars2 (Xtr)...wars2 (Dre)...Wars2 (Mmu)
Gene Ontology
Source: GO:0006418
Synonyms:
- tRNA charging
Branch: biological process
Genes: WARS2 (Hsa)...wars2 (Dre)
Gene Ontology
Source: GO:0004812
Synonyms:
- aminoacyl-tRNA synthetase activity
- aminoacyl-tRNA synthetase auxiliary protein activity
Branch: molecular function
Genes: WARS2 (Hsa)...wars2 (Dre)
Gene Ontology
Source: GO:0001570
Synonyms:
- vascular morphogenesis
Branch: biological process
Genes: WARS2 (Hsa)...Wars2 (Rno)...Wars2 (Mmu)
Gene Ontology
Source: GO:0045766
Synonyms:
- activation of angiogenesis
- stimulation of angiogenesis
Branch: biological process
Genes: Wars2 (Mmu)...WARS2 (Hsa)...Wars2 (Rno)
Gene Ontology
Source: GO:0002040
Synonyms: Not Available
Branch: biological process
Genes: wars2 (Dre)
Gene Ontology
Source: GO:0005759
Synonyms:
- mitochondrial lumen
- mitochondrial stroma
Branch: cellular component
Genes: wars2 (Dre)...Wars2 (Mmu)...WARS2 (Hsa)...Wars2 (Rno)
Gene Ontology
Source: GO:0016874
Synonyms:
- synthetase activity
Branch: molecular function
Genes: wars2 (Dre)
sa41400
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-160601-7406
Genes: wars2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: splice_donor_variant
Diseases: Not Available
Variant Name: Not Available
Genes: wars2 (Dre)
sa41399
(Danio rerio)Allele/Variant
Source: ZFIN:ZDB-ALT-161003-17093
Genes: wars2 (Dre)
Synonyms: Not Available
Variant Type: point_mutation
Molecular Consequence: stop_gained
Diseases: Not Available
Variant Name: Not Available
Genes: wars2 (Dre)
Gene Ontology
Source: GO:0005654
Synonyms: Not Available
Branch: cellular component
Genes: Wars2 (Mmu)...WARS2 (Hsa)...Wars2 (Rno)
Gene Ontology
Source: GO:0006412
Synonyms:
- protein anabolism
- protein biosynthesis
Branch: biological process
Genes: WARS2 (Hsa)...wars2 (Dre)
(GRCh38)1:119076551C>G
(Homo sapiens)Allele/Variant
Source: rs139975529
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: non_coding_transcript_exon_variant, synonymous_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119076551C>G
(GRCh38)1:119076555T>C
(Homo sapiens)Allele/Variant
Source: rs1296437426
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119076555T>C
(GRCh38)1:119032981C>G
(Homo sapiens)Allele/Variant
Source: rs1370759242
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119032981C>G
(GRCh38)1:119032984A>G
(Homo sapiens)Allele/Variant
Source: rs1448970558
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119032984A>G
(GRCh38)1:119033006G>A
(Homo sapiens)Allele/Variant
Source: NC_000001.11:g.119033006G>A
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119033006G>A
(GRCh38)1:119033038C>T
(Homo sapiens)Allele/Variant
Source: rs376728283
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119033038C>T
(GRCh38)1:119076381G>A
(Homo sapiens)Allele/Variant
Source: rs753188889
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119076381G>A
(GRCh38)1:119076493C>G
(Homo sapiens)Allele/Variant
Source: NC_000001.11:g.119076493C>G
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, non_coding_transcript_exon_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119076493C>G
(GRCh38)1:119033197G>A
(Homo sapiens)Allele/Variant
Source: rs368914534
Genes: WARS2 (Hsa)
Synonyms: Not Available
Variant Type: SNP
Molecular Consequence: missense_variant, 3_prime_UTR_variant
Diseases: Not Available
Variant Name: (GRCh38)1:119033197G>A