Version: 8.0.0
Date: Tue Jan 28 2025
Vps35UAS.D650N
FB:FBal0316903Drosophila melanogaster
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Vps35UAS.D650N

Species
Drosophila melanogaster
Symbol
Vps35UAS.D650N
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Vps35[Scer\UAS.D650N]
  • Vps35[UAS.D650N]
Description
UASt regulatory sequences drive expression of a mutated form of Vps35 that carries an amino acid substitution equivalent to D620N in the orthologous human VPS35 gene, a change identified in a number of families with dominantly inherited, late-onset Parkinson's disease. (FlyBase curator comment: the mutation in the Vps35 gene is given as D650N in FBrf0229809, however analysis of the release 6.32 annotated gene model indicates the change to be D647N)
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
PBac{UAS-Vps35.D650N}
Expressed Components
Knock-down Targets
None
Regulatory Regions
  • UASt
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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