Disease

core binding factor acute myeloid leukemia

Definition
An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis.
Synonyms
None
Cross References
Parent Terms
Child Terms
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Sources of Associations

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