Version: 8.0.0
Date: Tue Jan 28 2025
MCD diffuse large B-cell lymphoma
DOID:0081066
SummaryAssociated GenesAssociated AllelesAssociated Models
Disease

MCD diffuse large B-cell lymphoma

Definition
A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding.
Synonyms
  • MCD DLBCL
Cross References
Parent Terms
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Sources of Associations

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