Version: 8.0.0
Date: Tue Jan 28 2025
ST2 diffuse large B-cell lymphoma
DOID:0081068
SummaryAssociated GenesAssociated AllelesAssociated Models
Disease

ST2 diffuse large B-cell lymphoma

Definition
A diffuse large B-cell lymphoma that is categorized as ST2 with high probability by the LymphGen algorithm. This is based on a combination of genetic features and ST2 DLBCLs often, but do not always, have missense or nonsense mutations affecting TET2 and NFKBIA. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting some combination of SGK1, ZFP36L1, SOCS1, HIST1H1E and CD83, which can be coding or non-coding.
Synonyms
  • ST2 DLBCL
Cross References
Not Available
Parent Terms
Child Terms
None
Sources of Associations

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      Associated Models

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