Version: 8.0.0
Date: Tue Jan 28 2025
Lewy body dementia
DOID:12217
SummaryAssociated GenesAssociated AllelesAssociated Models
Disease

Lewy body dementia

Definition
A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies.
Synonyms
  • Dementia with Lewy bodies
  • Diffuse Lewy body disease
Cross References
Parent Terms
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Sources of Associations

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