Gene

hry

Species
Drosophila melanogaster
Symbol
hry
Name
hairy
Synonyms
  • 8247
  • barrel
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and transcription corepressor binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; response to hypoxia; and salivary gland morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including adult CNS glial cell; anal pad; germ layer; gut section; and imaginal disc. Orthologous to human HES1 (hes family bHLH transcription factor 1).
FB Description
hairy (hry) encodes a bHLH transcriptional repressor that recruits the corepressor encoded by gro to target promoters. It is a pair-rule gene that contributes to embryonic segmentation and peripheral neurogenesis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10985
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
8.6760M8.6765M8.6770M8.6775M8.6780M8.6785M8.6790M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions