Gene

Mlc2

Species
Drosophila melanogaster
Symbol
Mlc2
Name
Myosin light chain 2
Synonyms
  • CG2184
  • Dmlc
Biotype
protein coding gene
Automated Description
Predicted to enable myosin heavy chain binding activity. Involved in flight; muscle system process; and myofibril assembly. Located in myofibril. Is expressed in several structures, including adult head; adult heart; border follicle cell; larval muscle cell; and larval muscle system. Used to study hypertrophic cardiomyopathy 10. Human ortholog(s) of this gene implicated in distal arthrogryposis type 1C; familial hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 10. Orthologous to several human genes including MYL10 (myosin light chain 10); MYL11 (myosin light chain 11); and MYL2 (myosin light chain 2).
FB Description
Myosin light chain 2 (Mlc2) encodes a subunit of the myosin complex involved in myofibril assembly. It contributes to different flight-related processes including wing beat frequency, and indirect flight muscle contraction.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23049
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
30.1715M30.1720M30.1725M30.1730M30.1735M30.1740M30.1745M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions