Version: 8.0.0
Date: Tue Jan 28 2025
qua
Drosophila melanogasterFB:FBgn0003187
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

qua

Species
Drosophila melanogaster
Symbol
qua
Name
quail
Synonyms
  • anon-WO0140519.71
  • CG6433
Biotype
protein coding gene
Automated Description
Enables actin binding activity. Involved in imaginal disc-derived wing hair organization. Located in cytoplasm. Colocalizes with actin filament. Is expressed in several structures, including border follicle cell; dorsal epidermis primordium; germline cell; gonad; and gut section. Human ortholog(s) of this gene implicated in Finnish type amyloidosis and nephrotic syndrome type 21. Orthologous to several human genes including AVIL (advillin); CAPG (capping actin protein, gelsolin like); and GSN (gelsolin).
FB Description
quail (qua) encodes a member of the Villin family of F-actin crosslinking proteins. It is involved in wing hair growth and oogenesis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11977
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
            Viewer Help
            17.487M17.488M17.489M17.490M17.491M17.492M17.493M17.494M17.495M17.496M17.497M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            qua molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              qua role
              qua genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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