Gene

sesB

Species
Drosophila melanogaster
Symbol
sesB
Name
stress-sensitive B
Synonyms
  • A/A-T
  • A/A-T/sesB
Biotype
protein coding gene
Automated Description
Enables ATP:ADP antiporter activity. Involved in several processes, including determination of adult lifespan; intracellular calcium ion homeostasis; and muscle cell cellular homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adult head; adult heart; adult main segment of Malpighian tubule; adult midgut; and gonad. Used to study epilepsy and mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45635
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
10.781M10.782M10.783M10.784M10.785M10.786M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions