Enables ATP:ADP antiporter activity. Involved in several processes, including determination of adult lifespan; intracellular calcium ion homeostasis; and muscle cell cellular homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adult head; adult heart; adult main segment of Malpighian tubule; adult midgut; and gonad. Used to study epilepsy and mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6).