Gene

C15

Species
Drosophila melanogaster
Symbol
C15
Name
C15
Synonyms
  • 311
  • 93Bal
Biotype
protein coding gene
Automated Description
Contributes to sequence-specific DNA binding activity. Involved in chaeta development; imaginal disc-derived appendage morphogenesis; and regulation of DNA-templated transcription. Part of protein-containing complex. Is expressed in several structures, including amnioserosa anlage; amnioserosa primordium; cardiogenic mesoderm; epithelium; and ganglia. Human ortholog(s) of this gene implicated in adult T-cell leukemia/lymphoma. Orthologous to several human genes including TLX2 (T cell leukemia homeobox 2).
FB Description
C15 (C15) encodes a transcription factor that regulates gene expression in the leg distal region.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45921
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            21.500M21.502M21.504M21.506M21.508M21.510M21.512M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            C15 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              C15 role
              C15 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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