Gene

Mbs

Species
Drosophila melanogaster
Symbol
Mbs
Name
Myosin binding subunit
Synonyms
  • 0573/06
  • 0953/04
Biotype
protein coding gene
Automated Description
Predicted to enable enzyme inhibitor activity and myosin phosphatase regulator activity. Involved in several processes, including germline ring canal formation; neuron differentiation; and regulation of compound eye photoreceptor development. Located in apical cortex. Colocalizes with apical junction complex. Is expressed in several structures, including embryonic/larval esophageal visceral muscle; female germline cyst; germarium; larval muscle cell; and larval muscle system. Orthologous to several human genes including PPP1R12B (protein phosphatase 1 regulatory subunit 12B).
FB Description
Myosin binding subunit (Mbs) encodes a regulatory subunit of myosin phosphatase. It interacts with the catalytic subunit of the myosin phosphatase encoded by flw. It is involved in cell movement in various biological processes and in the arrest of constriction of contractile rings and ring canals during oogenesis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24179
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
16.055M16.060M16.065M16.070M16.075M16.080M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions