Version: 8.0.0
Date: Tue Jan 28 2025
Cyp6a17
Drosophila melanogasterFB:FBgn0015714
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Cyp6a17

Species
Drosophila melanogaster
Symbol
Cyp6a17
Name
Cytochrome P450 6a17
Synonyms
  • 61D6S
  • 6a17
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Involved in thermosensory behavior. Is expressed in several structures, including adult head; adult mushroom body; adult pars intercerebralis; dorsal thoracic disc; and gut section. Human ortholog(s) of this gene implicated in familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43).
FB Description
Cytochrome P450-6a17 (Cyp6a17) encodes a member of the cytochrome P450 (CYP) family of proteins involved in the oxidation of diverse organic substrates. Cyp6a17 expression in the mushroom bodies of the brain is regulated by cAMP-dependent protein kinase (PKA) and is required for temperature preference behavior.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24292
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

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        Experimental condition
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          Cyp6a17 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
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            Genetic Interactions

            Cyp6a17 role
            Cyp6a17 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
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